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The map label for this gene is insF1 [H]

Identifier: 119716385

GI number: 119716385

Start: 2302776

End: 2303675

Strand: Direct

Name: insF1 [H]

Synonym: Noca_2154

Alternate gene names: 119716385

Gene position: 2302776-2303675 (Clockwise)

Preceding gene: 119716384

Following gene: 119716390

Centisome position: 46.19

GC content: 67.89

Gene sequence:

>900_bases
GTGACCCGCTTCCAGTTCGTCGCCGACCACCAGCACGCCTTCGAGGTGAAGCGGATGTGTGAGCTCGTCGAGATCGGACG
CTCGTCGTTCTACGCCTGGCAGGCTGCCGCGCCAGGCCGGGAGGCGCGGGCCGAGGCCGACGCCGAGCTCGCCGAGAAGA
TCCGGACGATCCACACCGAGGACAACACCATCGGAGCACCACGGGCGACCGCCGAGCTCAACGACGGCGTCGCGCCGAGC
GAACGGGTCAACCACAAGCGGGTCGCCCGGGTGATGCGTGAGCACGACATCCGCGGCTACCAACGCAAACGACGGGTCCG
GACCACGATCCCCGAGCCGTCGCAGCAGAAGGTGTCCGACCTGCTCAAGCGGGACTTCACCGCCGACGCGGCCAACCTCA
AGTACGTCGGCGACATCACGTACCTACCGATCGCGGACGGCACGAACCTGTACCTGGCCACCGTGATCGACTGCTACAGC
CGCCGAGTCGCGGGCTGGGCGGTCGCGGACCATATGCGCGTCGAGCTCGTCCAGGACGCCCTCAAGGCCGCCCAGCTCAC
CCGCGGCAGCCTCGCCGGCGCTGTGTTTCACAGCGACCACGGGTCGGTCTACACATCGAAGGACTACGCCAAGCTCTGCG
CCGACCTGGGCGTCACCCAGTCGATGGGTGCCGTCGGCACGAGCGCCGACAATGCACTCGCGGAGTCGTTCAACGCGACC
CTGAAACGCGAGGTCCTCCAAGACGCCAACGTGTGGCCTGACGAGACCACCTGCCGCCGCCAGGTGTTCCGGTGGCTCAT
CCGCTACAACAACCGCCGCCGGCACTCCTGGTGCCGCTACCAGTCCCCGGTCGCCTTCGAGACCGGCACCATCGCAGCTA
GGCTCCCGTCAGCTGCGTAA

Upstream 100 bases:

>100_bases
AGGCCAGGGTCCTCGAACTGGAGGTCAGCGAGCAGAAGCTCACCACCGAGCGTGAAATTCTCCGGTCGGCAGCCAAGTAT
TTCGCTGGGGAGACGCGCTG

Downstream 100 bases:

>100_bases
TCCAACCCCGTGTCCAAGAACCGGGGGTAAGGCCCGCCCTATCCCCGATCATGACGCAGGATGATCCATGCCTTATCGGG
CGCATTTCGTTGACCGGAAC

Product: integrase catalytic subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 299; Mature: 298

Protein sequence:

>299_residues
MTRFQFVADHQHAFEVKRMCELVEIGRSSFYAWQAAAPGREARAEADAELAEKIRTIHTEDNTIGAPRATAELNDGVAPS
ERVNHKRVARVMREHDIRGYQRKRRVRTTIPEPSQQKVSDLLKRDFTADAANLKYVGDITYLPIADGTNLYLATVIDCYS
RRVAGWAVADHMRVELVQDALKAAQLTRGSLAGAVFHSDHGSVYTSKDYAKLCADLGVTQSMGAVGTSADNALAESFNAT
LKREVLQDANVWPDETTCRRQVFRWLIRYNNRRRHSWCRYQSPVAFETGTIAARLPSAA

Sequences:

>Translated_299_residues
MTRFQFVADHQHAFEVKRMCELVEIGRSSFYAWQAAAPGREARAEADAELAEKIRTIHTEDNTIGAPRATAELNDGVAPS
ERVNHKRVARVMREHDIRGYQRKRRVRTTIPEPSQQKVSDLLKRDFTADAANLKYVGDITYLPIADGTNLYLATVIDCYS
RRVAGWAVADHMRVELVQDALKAAQLTRGSLAGAVFHSDHGSVYTSKDYAKLCADLGVTQSMGAVGTSADNALAESFNAT
LKREVLQDANVWPDETTCRRQVFRWLIRYNNRRRHSWCRYQSPVAFETGTIAARLPSAA
>Mature_298_residues
TRFQFVADHQHAFEVKRMCELVEIGRSSFYAWQAAAPGREARAEADAELAEKIRTIHTEDNTIGAPRATAELNDGVAPSE
RVNHKRVARVMREHDIRGYQRKRRVRTTIPEPSQQKVSDLLKRDFTADAANLKYVGDITYLPIADGTNLYLATVIDCYSR
RVAGWAVADHMRVELVQDALKAAQLTRGSLAGAVFHSDHGSVYTSKDYAKLCADLGVTQSMGAVGTSADNALAESFNATL
KREVLQDANVWPDETTCRRQVFRWLIRYNNRRRHSWCRYQSPVAFETGTIAARLPSAA

Specific function: Involved in the transposition of the insertion sequence IS3 [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 integrase catalytic domain [H]

Homologues:

Organism=Homo sapiens, GI310129419, Length=247, Percent_Identity=32.7935222672065, Blast_Score=118, Evalue=6e-27,
Organism=Escherichia coli, GI1788405, Length=292, Percent_Identity=33.2191780821918, Blast_Score=140, Evalue=1e-34,
Organism=Escherichia coli, GI1787263, Length=292, Percent_Identity=33.2191780821918, Blast_Score=140, Evalue=1e-34,
Organism=Escherichia coli, GI1786753, Length=292, Percent_Identity=33.2191780821918, Blast_Score=140, Evalue=1e-34,
Organism=Escherichia coli, GI1786570, Length=292, Percent_Identity=33.2191780821918, Blast_Score=140, Evalue=1e-34,
Organism=Escherichia coli, GI1786490, Length=292, Percent_Identity=33.2191780821918, Blast_Score=140, Evalue=1e-34,
Organism=Escherichia coli, GI1789981, Length=273, Percent_Identity=27.4725274725275, Blast_Score=100, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001584
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00665 rve [H]

EC number: NA

Molecular weight: Translated: 33542; Mature: 33411

Theoretical pI: Translated: 9.13; Mature: 9.13

Prosite motif: PS50994 INTEGRASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRFQFVADHQHAFEVKRMCELVEIGRSSFYAWQAAAPGREARAEADAELAEKIRTIHTE
CCCCEEECCHHHHHHHHHHHHHHHHCCHHHEEEECCCCCHHHHHHHHHHHHHHHHHHCCC
DNTIGAPRATAELNDGVAPSERVNHKRVARVMREHDIRGYQRKRRVRTTIPEPSQQKVSD
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCHHHHHH
LLKRDFTADAANLKYVGDITYLPIADGTNLYLATVIDCYSRRVAGWAVADHMRVELVQDA
HHHHCCCCCCCCEEEECCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LKAAQLTRGSLAGAVFHSDHGSVYTSKDYAKLCADLGVTQSMGAVGTSADNALAESFNAT
HHHHHHHHHHHHHHEEECCCCCEEECHHHHHHHHHCCCHHHHCCCCCCCHHHHHHHHHHH
LKREVLQDANVWPDETTCRRQVFRWLIRYNNRRRHSWCRYQSPVAFETGTIAARLPSAA
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHCCCCCEEECCCHHCCCCCCC
>Mature Secondary Structure 
TRFQFVADHQHAFEVKRMCELVEIGRSSFYAWQAAAPGREARAEADAELAEKIRTIHTE
CCCEEECCHHHHHHHHHHHHHHHHCCHHHEEEECCCCCHHHHHHHHHHHHHHHHHHCCC
DNTIGAPRATAELNDGVAPSERVNHKRVARVMREHDIRGYQRKRRVRTTIPEPSQQKVSD
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCHHHHHH
LLKRDFTADAANLKYVGDITYLPIADGTNLYLATVIDCYSRRVAGWAVADHMRVELVQDA
HHHHCCCCCCCCEEEECCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LKAAQLTRGSLAGAVFHSDHGSVYTSKDYAKLCADLGVTQSMGAVGTSADNALAESFNAT
HHHHHHHHHHHHHHEEECCCCCEEECHHHHHHHHHCCCHHHHCCCCCCCHHHHHHHHHHH
LKREVLQDANVWPDETTCRRQVFRWLIRYNNRRRHSWCRYQSPVAFETGTIAARLPSAA
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHCCCCCEEECCCHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2987844; 9278503 [H]