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The map label for this gene is mhpF [C]

Identifier: 119716381

GI number: 119716381

Start: 2299475

End: 2300419

Strand: Reverse

Name: mhpF [C]

Synonym: Noca_2150

Alternate gene names: 119716381

Gene position: 2300419-2299475 (Counterclockwise)

Preceding gene: 119716382

Following gene: 119716380

Centisome position: 46.14

GC content: 60.85

Gene sequence:

>945_bases
GTGACTGCATCAACGATTCCCCGTCAAATCGCCATCATCGGCTCCGGCAACATCGGTACTGATCTGATGATTAAGGTTCT
GCGGCTATCAAAGACGCTTGAGGTCGGAGCGATGGTTGGCATTGACCCCGATAGCGACGGGCTCGCACGCGCGAACCGGC
TCGGAGTACCTACGACCTCGGACGGGGTTGACGGCCTGATTCGCATGCCCAACTTCGAGGCCATCGACATCGTGCTCGAC
GCGACCTCTGCCCGCGCCCACGCTGCCAACTACACCGCCCTCAGGCGCTACCGCAAGCGAATGATCGACCTGACACCTGC
AGCCGTCGGACCGTTCGTAGTGCCCGCCGTCAACATGGGCGCGAGCCTCTCTGCAGACAACGTCAACATGGTGACGTGCG
GCGGGCAAGCCACTATCCCGATCGTCGCGGCAATTTCCCAAGTCACTCCTGTTGCGTATGCGGAAATCGTCGCTTCAATT
GCATCGAAGTCGGCGGGGCCTGGAACACGTCAGAACATCGATGAGTTCACCGAGACGACGGCCCACGCCATCGAGCAGGT
CGGCGGTGCCCGGAAGGGGAAGGCCATCATCATTCTGAACCCTGCGGAGCCACCTCTCATCATGCGTGACACGGTTCTTG
CGCTCATCGGACCTTCCGACCACGACGCGGTCAAGGGGTCCATACGTGCGATGGTTGATGCTGTTGCCGAGTACGTCCCC
GGGTATCGCCTCAAGCAGCGTATTGAAATTCAGCCGTTGGACGGACTGCCGGTCGGGACGCTCACCTCGGAGCCCGTCAC
ACACAAGGTGAGCGTCTTTCTGGAAGTAGAGGGCGCAGCGCACTACCTGCCGGCATATGCAGGCAATCTCGACATCATGA
CCTCCGCAGCGTTGCGTGTTGCGGAAGCGATGGCAGCCCAGAAACTCAGCGGAGCAGTGGCGTGA

Upstream 100 bases:

>100_bases
CTCTCGGTCCAATGGTCACCGTTCACCCGGGTATGACGGCCGTGGCCAACATCAACGGTCTCGGGACCGTGTCCGCATCT
TTCGGCATAGGAGAGAAGCC

Downstream 100 bases:

>100_bases
ACGAAACGCGTACGACTGTCTTTGTCCAGGACGTCACTCTCCGCGACGGCATGCACGCCATCCGACACCAGCTTGCGCCC
GGCGAGGTAGCCCAGATTGC

Product: acetaldehyde dehydrogenase

Products: NA

Alternate protein names: Acetaldehyde dehydrogenase [acetylating] 2

Number of amino acids: Translated: 314; Mature: 313

Protein sequence:

>314_residues
MTASTIPRQIAIIGSGNIGTDLMIKVLRLSKTLEVGAMVGIDPDSDGLARANRLGVPTTSDGVDGLIRMPNFEAIDIVLD
ATSARAHAANYTALRRYRKRMIDLTPAAVGPFVVPAVNMGASLSADNVNMVTCGGQATIPIVAAISQVTPVAYAEIVASI
ASKSAGPGTRQNIDEFTETTAHAIEQVGGARKGKAIIILNPAEPPLIMRDTVLALIGPSDHDAVKGSIRAMVDAVAEYVP
GYRLKQRIEIQPLDGLPVGTLTSEPVTHKVSVFLEVEGAAHYLPAYAGNLDIMTSAALRVAEAMAAQKLSGAVA

Sequences:

>Translated_314_residues
MTASTIPRQIAIIGSGNIGTDLMIKVLRLSKTLEVGAMVGIDPDSDGLARANRLGVPTTSDGVDGLIRMPNFEAIDIVLD
ATSARAHAANYTALRRYRKRMIDLTPAAVGPFVVPAVNMGASLSADNVNMVTCGGQATIPIVAAISQVTPVAYAEIVASI
ASKSAGPGTRQNIDEFTETTAHAIEQVGGARKGKAIIILNPAEPPLIMRDTVLALIGPSDHDAVKGSIRAMVDAVAEYVP
GYRLKQRIEIQPLDGLPVGTLTSEPVTHKVSVFLEVEGAAHYLPAYAGNLDIMTSAALRVAEAMAAQKLSGAVA
>Mature_313_residues
TASTIPRQIAIIGSGNIGTDLMIKVLRLSKTLEVGAMVGIDPDSDGLARANRLGVPTTSDGVDGLIRMPNFEAIDIVLDA
TSARAHAANYTALRRYRKRMIDLTPAAVGPFVVPAVNMGASLSADNVNMVTCGGQATIPIVAAISQVTPVAYAEIVASIA
SKSAGPGTRQNIDEFTETTAHAIEQVGGARKGKAIIILNPAEPPLIMRDTVLALIGPSDHDAVKGSIRAMVDAVAEYVPG
YRLKQRIEIQPLDGLPVGTLTSEPVTHKVSVFLEVEGAAHYLPAYAGNLDIMTSAALRVAEAMAAQKLSGAVA

Specific function: Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta- cleavage pathway for the degradation of aromatic compounds

COG id: COG4569

COG function: function code Q; Acetaldehyde dehydrogenase (acetylating)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetaldehyde dehydrogenase family

Homologues:

Organism=Escherichia coli, GI1786547, Length=306, Percent_Identity=65.359477124183, Blast_Score=377, Evalue=1e-106,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACDH2_NOCSJ (A1SIM4)

Other databases:

- EMBL:   CP000509
- RefSeq:   YP_923346.1
- ProteinModelPortal:   A1SIM4
- SMR:   A1SIM4
- STRING:   A1SIM4
- GeneID:   4599210
- GenomeReviews:   CP000509_GR
- KEGG:   nca:Noca_2150
- eggNOG:   COG4569
- HOGENOM:   HBG300125
- OMA:   ANAHRAN
- ProtClustDB:   PRK08300
- BioCyc:   NSP35761:NOCA_2150-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01657
- InterPro:   IPR003361
- InterPro:   IPR015426
- InterPro:   IPR016040
- InterPro:   IPR000534
- Gene3D:   G3DSA:3.40.50.720
- PANTHER:   PTHR21123
- PIRSF:   PIRSF015689
- SMART:   SM00859
- TIGRFAMs:   TIGR03215

Pfam domain/function: PF09290 AcetDehyd-dimer; PF01118 Semialdhyde_dh

EC number: =1.2.1.10

Molecular weight: Translated: 32725; Mature: 32594

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: BINDING 289-289

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTASTIPRQIAIIGSGNIGTDLMIKVLRLSKTLEVGAMVGIDPDSDGLARANRLGVPTTS
CCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCEEEECCCCCCCHHHHHCCCCCCCC
DGVDGLIRMPNFEAIDIVLDATSARAHAANYTALRRYRKRMIDLTPAAVGPFVVPAVNMG
CCCCCEEECCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCHHCCCEEEHHCCCC
ASLSADNVNMVTCGGQATIPIVAAISQVTPVAYAEIVASIASKSAGPGTRQNIDEFTETT
CCCCCCCEEEEEECCCCCHHHHHHHHHHCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
AHAIEQVGGARKGKAIIILNPAEPPLIMRDTVLALIGPSDHDAVKGSIRAMVDAVAEYVP
HHHHHHHCCCCCCCEEEEECCCCCCEEECCEEEEEECCCCCHHHHHHHHHHHHHHHHHCC
GYRLKQRIEIQPLDGLPVGTLTSEPVTHKVSVFLEVEGAAHYLPAYAGNLDIMTSAALRV
CCCHHHEEEEECCCCCCCCCCCCCCCCEEEEEEEEECCCCCCCCHHCCCCHHHHHHHHHH
AEAMAAQKLSGAVA
HHHHHHHHHHCCCC
>Mature Secondary Structure 
TASTIPRQIAIIGSGNIGTDLMIKVLRLSKTLEVGAMVGIDPDSDGLARANRLGVPTTS
CCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCEEEECCCCCCCHHHHHCCCCCCCC
DGVDGLIRMPNFEAIDIVLDATSARAHAANYTALRRYRKRMIDLTPAAVGPFVVPAVNMG
CCCCCEEECCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCHHCCCEEEHHCCCC
ASLSADNVNMVTCGGQATIPIVAAISQVTPVAYAEIVASIASKSAGPGTRQNIDEFTETT
CCCCCCCEEEEEECCCCCHHHHHHHHHHCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
AHAIEQVGGARKGKAIIILNPAEPPLIMRDTVLALIGPSDHDAVKGSIRAMVDAVAEYVP
HHHHHHHCCCCCCCEEEEECCCCCCEEECCEEEEEECCCCCHHHHHHHHHHHHHHHHHCC
GYRLKQRIEIQPLDGLPVGTLTSEPVTHKVSVFLEVEGAAHYLPAYAGNLDIMTSAALRV
CCCHHHEEEEECCCCCCCCCCCCCCCCEEEEEEEEECCCCCCCCHHCCCCHHHHHHHHHH
AEAMAAQKLSGAVA
HHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA