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The map label for this gene is livH [C]

Identifier: 119716378

GI number: 119716378

Start: 2296178

End: 2297050

Strand: Reverse

Name: livH [C]

Synonym: Noca_2147

Alternate gene names: 119716378

Gene position: 2297050-2296178 (Counterclockwise)

Preceding gene: 119716379

Following gene: 119716377

Centisome position: 46.07

GC content: 61.74

Gene sequence:

>873_bases
TTGCATACCTTTTGGGTCCTGCTAGTCGCAGGCATCACAAGTGGCGCGGTATATGGCCTACTCGCGGTAGCGATCTGCCT
CACCTATAGGGTCTCCAAGGTCATCAACGCGGCTATCGGTGAGTTGATGGTCCTTGGAGCCCTGATCGCATCGTCGCTGA
TCGGTAGGGGCTGGCCGCTCGCGATCGCTGTTGTGGTCGGCGTCGGCGTGGTCGGCCTGGTCGCGGCTGCCTTTAGTGGC
ATCATTCTTCGCCCAGCCATCAAGGCGAAGTCGACCATGAGTCAGCTGCTCCTCGTCACCTTCTCTCTCAGCATCCTCTT
GCAGGGCGTCATGCTCGTCGCCTACGGCCGAGACATTCACTCCGCGCCAGCGTGGATCGGCGGTGACGGGATGACGATCG
GCGGAGTGGTCCTCCAGCCCCAGCGGCTTCTGATCCTCGCCGCCACGCTCGCGCTGGGAACCGGCCTCGTCCTTTACTTC
TCCAGGTCGGTGCACGGCAGGGCGATGACCGCGACATCCCAGAACCCTGTGGGAGCAGCGCTTGTCGGAATCAGCGTGAG
CCGATTCCGAGACGTAGCGTTCGTTGGAACCGCCGTCATCGCCGCGCTCCTCGGCTGCATGCTTATCCCCATCACTCCCT
TCGTGTACAACGCAGGCCTGCCCCTCGCACTTGTCGGGATGGTGGGCGCCACACTCGCTCGATTCGTGAACATTGGCGTA
GCCATGGCTGCCGGCATCGTCATCGGCGTCCTTGAGCAGATGATTGCTCGCTACGTCTCTGCGGATCTGCAAACCTCACT
CGTCTACATCGTGCTGACCGTTCTTATGTTGGCGGTACCCAGCGCATTCGCCACAGCTAAGGCCAGGGCATGA

Upstream 100 bases:

>100_bases
CGCACTGGGCGGGTACGTCCTGGTGAAGTACGACGATGGTCAGTGGCACCCCATCGACGAATAGTAAAAACCCGAGTCCG
ATCCAGATTGAGGTTGAGAG

Downstream 100 bases:

>100_bases
ACGAATCGACCGTCCGTCATGCGCGGAGCGCAACTCCCGTACTGATCGCGATCGCAGTGTTCGCACTGCTGGTCGCGTCC
CTTGGAGACTCGTACCGAAC

Product: inner-membrane translocator

Products: ADP; phosphate; L-valine [Cytoplasm]; ADP; L-iso-leucine [Cytoplasm]; L-leucine [Cytoplasm] [C]

Alternate protein names: ABC Transporter Permease Protein; Branched Chain Amino Acid ABC Transporter Permease; ABC-Transporter Permease Component; Transmembrane Component Of ABC Transporter; Amino Acid Or Sugar ABC Transport System Permease Protein; Branched-Chain Amino Acid ABC Transporter Permease; Branched-Chain Amino Acid ABC Transporter Membrane Protein; Branched-Chain Amino Acid Transport System Permease; Branched Amino Acid Transport System Permease; Urea Or Short-Chain Amide ABC Transporter; Branched-Chain Amino Acid ABC Transporter; Amino Acid/Amide Abc Transporter Membrane Haat Family

Number of amino acids: Translated: 290; Mature: 290

Protein sequence:

>290_residues
MHTFWVLLVAGITSGAVYGLLAVAICLTYRVSKVINAAIGELMVLGALIASSLIGRGWPLAIAVVVGVGVVGLVAAAFSG
IILRPAIKAKSTMSQLLLVTFSLSILLQGVMLVAYGRDIHSAPAWIGGDGMTIGGVVLQPQRLLILAATLALGTGLVLYF
SRSVHGRAMTATSQNPVGAALVGISVSRFRDVAFVGTAVIAALLGCMLIPITPFVYNAGLPLALVGMVGATLARFVNIGV
AMAAGIVIGVLEQMIARYVSADLQTSLVYIVLTVLMLAVPSAFATAKARA

Sequences:

>Translated_290_residues
MHTFWVLLVAGITSGAVYGLLAVAICLTYRVSKVINAAIGELMVLGALIASSLIGRGWPLAIAVVVGVGVVGLVAAAFSG
IILRPAIKAKSTMSQLLLVTFSLSILLQGVMLVAYGRDIHSAPAWIGGDGMTIGGVVLQPQRLLILAATLALGTGLVLYF
SRSVHGRAMTATSQNPVGAALVGISVSRFRDVAFVGTAVIAALLGCMLIPITPFVYNAGLPLALVGMVGATLARFVNIGV
AMAAGIVIGVLEQMIARYVSADLQTSLVYIVLTVLMLAVPSAFATAKARA
>Mature_290_residues
MHTFWVLLVAGITSGAVYGLLAVAICLTYRVSKVINAAIGELMVLGALIASSLIGRGWPLAIAVVVGVGVVGLVAAAFSG
IILRPAIKAKSTMSQLLLVTFSLSILLQGVMLVAYGRDIHSAPAWIGGDGMTIGGVVLQPQRLLILAATLALGTGLVLYF
SRSVHGRAMTATSQNPVGAALVGISVSRFRDVAFVGTAVIAALLGCMLIPITPFVYNAGLPLALVGMVGATLARFVNIGV
AMAAGIVIGVLEQMIARYVSADLQTSLVYIVLTVLMLAVPSAFATAKARA

Specific function: Part Of The Binding-Protein-Dependent Transport System For Branched-Chain Amino Acids. Probably Responsible For The Translocation Of The Substrates Across The Membrane. [C]

COG id: COG0559

COG function: function code E; Branched-chain amino acid ABC-type transport system, permease components

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1789866, Length=294, Percent_Identity=25.5102040816327, Blast_Score=61, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 29740; Mature: 29740

Theoretical pI: Translated: 10.60; Mature: 10.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHTFWVLLVAGITSGAVYGLLAVAICLTYRVSKVINAAIGELMVLGALIASSLIGRGWPL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
AIAVVVGVGVVGLVAAAFSGIILRPAIKAKSTMSQLLLVTFSLSILLQGVMLVAYGRDIH
HHHHHHHHHHHHHHHHHHHCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
SAPAWIGGDGMTIGGVVLQPQRLLILAATLALGTGLVLYFSRSVHGRAMTATSQNPVGAA
CCCCEECCCCCEECCEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCHH
LVGISVSRFRDVAFVGTAVIAALLGCMLIPITPFVYNAGLPLALVGMVGATLARFVNIGV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
AMAAGIVIGVLEQMIARYVSADLQTSLVYIVLTVLMLAVPSAFATAKARA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCCC
>Mature Secondary Structure
MHTFWVLLVAGITSGAVYGLLAVAICLTYRVSKVINAAIGELMVLGALIASSLIGRGWPL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
AIAVVVGVGVVGLVAAAFSGIILRPAIKAKSTMSQLLLVTFSLSILLQGVMLVAYGRDIH
HHHHHHHHHHHHHHHHHHHCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
SAPAWIGGDGMTIGGVVLQPQRLLILAATLALGTGLVLYFSRSVHGRAMTATSQNPVGAA
CCCCEECCCCCEECCEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCHH
LVGISVSRFRDVAFVGTAVIAALLGCMLIPITPFVYNAGLPLALVGMVGATLARFVNIGV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
AMAAGIVIGVLEQMIARYVSADLQTSLVYIVLTVLMLAVPSAFATAKARA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-valine [Periplasm]; H2O; ATP; L-iso-leucine [Periplasm]; L-leucine [Periplasm] [C]

Specific reaction: ATP + L-valine [Periplasm] + H2O = ADP + phosphate + L-valine [Cytoplasm] ATP + L-iso-leucine [Periplasm] + H2O = ADP + phosphate + L-iso-leucine [Cytoplasm] ATP + L-leucine [Periplasm] + H2O = ADP + phosphate + L-leucine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA