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The map label for this gene is hoxN [H]

Identifier: 119716355

GI number: 119716355

Start: 2271013

End: 2272056

Strand: Reverse

Name: hoxN [H]

Synonym: Noca_2124

Alternate gene names: 119716355

Gene position: 2272056-2271013 (Counterclockwise)

Preceding gene: 119716357

Following gene: 119716346

Centisome position: 45.57

GC content: 62.84

Gene sequence:

>1044_bases
ATGTCTCAGTCCCGCCGACAACTCACCTTGGTGGCCGTCGTCGCTCTGGCGCTCAATGTTGTTGGCTGGGGCACCCTCGT
TCTTGCGGTGCTTCCGCATGCCTACCAGATCGGCAACGCCGGTGTCTTCGGCCTGGGCGTAGGCGTGACCGCGTTCTTGC
TCGGCGCCCGCCACGCCTTCGATGCTGATCACATCACGATCATCGACAACGCGACCCGCAAGCTCGTCAATGACGGCAAG
GCTGCTCGCAGCACTGGCCTGTGGTTCGCTCTGGGCCATTCGAGCGTGGTCTTCGGGCTCGCCGCGGTCATCGCACTGGG
TGTTACGGCCGTCGCCGGGCCAGTGCAAGACGCCGACTCCCAGTTGCAGCACACCCTGGGGGTCATCGGCTCCTCTGCGG
CCGGGTTCTTCCTCGTCGCGGTCGGCCTCATGAACATGAACGCTCTGACGGGCATACTGCACGCCCGGCGTCACATCAAA
GCGGGAACATTCGACGAACATCGTCTCGAGCACCACCTCCACAGCCGCGGCATCCTGGCAAAGCTCTTCAGTCGCGTCAT
CAAGAAGATCGACAAGCCGTGGCACCTGTACCCTGCCGGTCTGCTGATGGGTCTCGGCTTCGACACAGCTACCCAGGTCG
CGCTTCTGGTCCTTGCCGGTGGAACGGCGGCGTACGCGCTTCCGTGGTACGCGGTGATGGTCCTGCCCGTGTTGTTCACC
GCCGGCATGGTGATCGGCGACAGCACCGACGGCATCGTCATGTCGCGTGCGTACGAGTGGTCCTCGGACGACCCGAAGCG
TCGGATCACGTACAACGCCGTCATCACGCTGCTGTCGGTGCTTATCGCACTTACCATAGGAACGATCCTGCTAGTGCAGC
TGGTGGCTGAGGAGTTCAGCATCAGCTGGCTTTCGGGATCGACAGCCCTCAATCTCGACTACGTGGGGTTCGGCATCGTC
GCCGTCTTCGTCATCGTTTGGACGGTGGGCCTTCTGACGATCAACGCCAGACGGTCACGGACGCTCATGGAGTCGGACAC
CTGA

Upstream 100 bases:

>100_bases
TGCACGACCCGGGCCGGCCACGGGAGGAGGGCGCGACGTGAGACACCCCTCAGCACCTATTGCGAACTGTTTGCAATAAC
ATTGTGGTGTGAATGACGCG

Downstream 100 bases:

>100_bases
AGTTCGGTAAACCGCGGAACGTCGGTCTCGTACTCGAACACCAGCGGGTGAGGTTGGCGACGGCGACGAGGATGTGCGCG
GCAGCCGCGTCTCGCGGAAT

Product: high-affinity nickel-transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 347; Mature: 346

Protein sequence:

>347_residues
MSQSRRQLTLVAVVALALNVVGWGTLVLAVLPHAYQIGNAGVFGLGVGVTAFLLGARHAFDADHITIIDNATRKLVNDGK
AARSTGLWFALGHSSVVFGLAAVIALGVTAVAGPVQDADSQLQHTLGVIGSSAAGFFLVAVGLMNMNALTGILHARRHIK
AGTFDEHRLEHHLHSRGILAKLFSRVIKKIDKPWHLYPAGLLMGLGFDTATQVALLVLAGGTAAYALPWYAVMVLPVLFT
AGMVIGDSTDGIVMSRAYEWSSDDPKRRITYNAVITLLSVLIALTIGTILLVQLVAEEFSISWLSGSTALNLDYVGFGIV
AVFVIVWTVGLLTINARRSRTLMESDT

Sequences:

>Translated_347_residues
MSQSRRQLTLVAVVALALNVVGWGTLVLAVLPHAYQIGNAGVFGLGVGVTAFLLGARHAFDADHITIIDNATRKLVNDGK
AARSTGLWFALGHSSVVFGLAAVIALGVTAVAGPVQDADSQLQHTLGVIGSSAAGFFLVAVGLMNMNALTGILHARRHIK
AGTFDEHRLEHHLHSRGILAKLFSRVIKKIDKPWHLYPAGLLMGLGFDTATQVALLVLAGGTAAYALPWYAVMVLPVLFT
AGMVIGDSTDGIVMSRAYEWSSDDPKRRITYNAVITLLSVLIALTIGTILLVQLVAEEFSISWLSGSTALNLDYVGFGIV
AVFVIVWTVGLLTINARRSRTLMESDT
>Mature_346_residues
SQSRRQLTLVAVVALALNVVGWGTLVLAVLPHAYQIGNAGVFGLGVGVTAFLLGARHAFDADHITIIDNATRKLVNDGKA
ARSTGLWFALGHSSVVFGLAAVIALGVTAVAGPVQDADSQLQHTLGVIGSSAAGFFLVAVGLMNMNALTGILHARRHIKA
GTFDEHRLEHHLHSRGILAKLFSRVIKKIDKPWHLYPAGLLMGLGFDTATQVALLVLAGGTAAYALPWYAVMVLPVLFTA
GMVIGDSTDGIVMSRAYEWSSDDPKRRITYNAVITLLSVLIALTIGTILLVQLVAEEFSISWLSGSTALNLDYVGFGIVA
VFVIVWTVGLLTINARRSRTLMESDT

Specific function: High-affinity nickel transporter responsible for nickel uptake. Necessary for high levels of activity of hydrogenase and urease [H]

COG id: COG3376

COG function: function code P; High-affinity nickel permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NiCoT transporter (TC 2.A.52) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004688
- InterPro:   IPR011541 [H]

Pfam domain/function: PF03824 NicO [H]

EC number: NA

Molecular weight: Translated: 36917; Mature: 36785

Theoretical pI: Translated: 9.58; Mature: 9.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQSRRQLTLVAVVALALNVVGWGTLVLAVLPHAYQIGNAGVFGLGVGVTAFLLGARHAF
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHCC
DADHITIIDNATRKLVNDGKAARSTGLWFALGHSSVVFGLAAVIALGVTAVAGPVQDADS
CCCCEEEEEHHHHHHHCCCCHHHHCCCEEEECCHHHHHHHHHHHHHHHHHHCCCCCCHHH
QLQHTLGVIGSSAAGFFLVAVGLMNMNALTGILHARRHIKAGTFDEHRLEHHLHSRGILA
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCHHH
KLFSRVIKKIDKPWHLYPAGLLMGLGFDTATQVALLVLAGGTAAYALPWYAVMVLPVLFT
HHHHHHHHHCCCCCEEEHHHHHHHCCCCHHHHHHHHHEECCCHHHHHHHHHHHHHHHHHH
AGMVIGDSTDGIVMSRAYEWSSDDPKRRITYNAVITLLSVLIALTIGTILLVQLVAEEFS
CCEEEECCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
ISWLSGSTALNLDYVGFGIVAVFVIVWTVGLLTINARRSRTLMESDT
EEEECCCCEEEEHHHHHHHHHHHHHHHHHHHHEECCHHCCCHHCCCC
>Mature Secondary Structure 
SQSRRQLTLVAVVALALNVVGWGTLVLAVLPHAYQIGNAGVFGLGVGVTAFLLGARHAF
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHCC
DADHITIIDNATRKLVNDGKAARSTGLWFALGHSSVVFGLAAVIALGVTAVAGPVQDADS
CCCCEEEEEHHHHHHHCCCCHHHHCCCEEEECCHHHHHHHHHHHHHHHHHHCCCCCCHHH
QLQHTLGVIGSSAAGFFLVAVGLMNMNALTGILHARRHIKAGTFDEHRLEHHLHSRGILA
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCHHH
KLFSRVIKKIDKPWHLYPAGLLMGLGFDTATQVALLVLAGGTAAYALPWYAVMVLPVLFT
HHHHHHHHHCCCCCEEEHHHHHHHCCCCHHHHHHHHHEECCCHHHHHHHHHHHHHHHHHH
AGMVIGDSTDGIVMSRAYEWSSDDPKRRITYNAVITLLSVLIALTIGTILLVQLVAEEFS
CCEEEECCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
ISWLSGSTALNLDYVGFGIVAVFVIVWTVGLLTINARRSRTLMESDT
EEEECCCCEEEEHHHHHHHHHHHHHHHHHHHHEECCHHCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1847142; 7896709; 12948488; 7934894 [H]