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The map label for this gene is mhpD [H]

Identifier: 119716286

GI number: 119716286

Start: 2199708

End: 2200487

Strand: Direct

Name: mhpD [H]

Synonym: Noca_2055

Alternate gene names: 119716286

Gene position: 2199708-2200487 (Clockwise)

Preceding gene: 119716285

Following gene: 119716290

Centisome position: 44.12

GC content: 75.51

Gene sequence:

>780_bases
GTGAATCCCCGCCACGCCGCCGACCTGCTCCGCGCCGCGCGGGTCGAGCACCGCACGCTCTCGCCCTTCACCGACGAGCA
CCCCGAGCTCGACGAGGACTGGGGGTACGCCGTGCAGGCGCTCGCCCTCGACGACCGGGTCGCTGCGGGCGACCCGGTCG
TGGGCGCGAAGCTGGGGCTGACCAGCCGCGCCAAGCAGGAGCGGATGGGGGTGGACCGCCCGATCGTCGGCTTCCTCACC
CGCTCGATGCTGCTCGAGCCCGACGGGGTCGGGGACTCCCTGGAGCACTGGGCCCAGCCGCGGATCGAGCCGGAGATCGC
GTTCGTCACCGGACGGGCCATCGACCGGGCGCTCGACGCCGACGAGGTGAGGGCCGGCGTCGCCAGCGTCGGCGTCGCGG
CCGAGATCCTCGACTCCCGGTGGACCGGCTACCGGTTCCGGCTGCCCGACGTCGTCGCCGACGAGACCAGCGCCGCCGGG
GTTCTCCTCGGTGCCTCGCCGGTCCCGTGGCCGGCCGACCTGGACCTGGCGTCGGCCCGCTGCGAGGTCGAGGTCGACGG
CGAGGTCGTCCACCGCTCGACCGGCGCCGCGATCCTGGGTGACCCGTGGCGCGCGCTCAGCCTGCTCTCCGAGCACCTCG
AGCGGCACGGGCGATCGCTCCCGGCCGGGTCGCTCGTGCTGGCCGGCGCGCTGACGGACGCCGTACCCCTGCAGGCCGGG
AGCCGCTATCGGCTCAGCGTCGAGGGCCTGGGCACGATCACGGTCGGGCCCACGGCGTAG

Upstream 100 bases:

>100_bases
CCCGCGGCATGGTGATGGTCTACGGCCCCCGCGACGCCGCGGAGCTCGAGGTCGTCGCCGGCATCGTGGCTGCCAGCCAC
GCCTACGCGACGATGGCCGG

Downstream 100 bases:

>100_bases
CGGTCAGTCGATCTCCTCCCCGGCCAGGGCCTTCGAGGCCAGCCGCTCCTCCTCGCTGACCTCCCAGACCTCCCAGGCGG
CGTGCGCGGCCAGCAGGATG

Product: 4-oxalocrotonate decarboxylase

Products: NA

Alternate protein names: 2-hydroxypentadienoic acid hydratase [H]

Number of amino acids: Translated: 259; Mature: 259

Protein sequence:

>259_residues
MNPRHAADLLRAARVEHRTLSPFTDEHPELDEDWGYAVQALALDDRVAAGDPVVGAKLGLTSRAKQERMGVDRPIVGFLT
RSMLLEPDGVGDSLEHWAQPRIEPEIAFVTGRAIDRALDADEVRAGVASVGVAAEILDSRWTGYRFRLPDVVADETSAAG
VLLGASPVPWPADLDLASARCEVEVDGEVVHRSTGAAILGDPWRALSLLSEHLERHGRSLPAGSLVLAGALTDAVPLQAG
SRYRLSVEGLGTITVGPTA

Sequences:

>Translated_259_residues
MNPRHAADLLRAARVEHRTLSPFTDEHPELDEDWGYAVQALALDDRVAAGDPVVGAKLGLTSRAKQERMGVDRPIVGFLT
RSMLLEPDGVGDSLEHWAQPRIEPEIAFVTGRAIDRALDADEVRAGVASVGVAAEILDSRWTGYRFRLPDVVADETSAAG
VLLGASPVPWPADLDLASARCEVEVDGEVVHRSTGAAILGDPWRALSLLSEHLERHGRSLPAGSLVLAGALTDAVPLQAG
SRYRLSVEGLGTITVGPTA
>Mature_259_residues
MNPRHAADLLRAARVEHRTLSPFTDEHPELDEDWGYAVQALALDDRVAAGDPVVGAKLGLTSRAKQERMGVDRPIVGFLT
RSMLLEPDGVGDSLEHWAQPRIEPEIAFVTGRAIDRALDADEVRAGVASVGVAAEILDSRWTGYRFRLPDVVADETSAAG
VLLGASPVPWPADLDLASARCEVEVDGEVVHRSTGAAILGDPWRALSLLSEHLERHGRSLPAGSLVLAGALTDAVPLQAG
SRYRLSVEGLGTITVGPTA

Specific function: Catalyzes the conversion of 2-hydroxypentadienoic acid (enolic form of 2-oxopent-4-enoate) to 4-hydroxy-2-ketopentanoic acid [H]

COG id: COG3971

COG function: function code Q; 2-keto-4-pentenoate hydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hydratase/decarboxylase family. MhpD subfamily [H]

Homologues:

Organism=Escherichia coli, GI87081722, Length=253, Percent_Identity=33.201581027668, Blast_Score=108, Evalue=4e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002529
- InterPro:   IPR011234 [H]

Pfam domain/function: PF01557 FAA_hydrolase [H]

EC number: =4.2.1.80 [H]

Molecular weight: Translated: 27567; Mature: 27567

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPRHAADLLRAARVEHRTLSPFTDEHPELDEDWGYAVQALALDDRVAAGDPVVGAKLGL
CCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCC
TSRAKQERMGVDRPIVGFLTRSMLLEPDGVGDSLEHWAQPRIEPEIAFVTGRAIDRALDA
CHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCHHHHHHCCCCCCCEEEEEECHHHHHHCCH
DEVRAGVASVGVAAEILDSRWTGYRFRLPDVVADETSAAGVLLGASPVPWPADLDLASAR
HHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHCCCCCCCEEEECCCCCCCCCCCCCCCCE
CEVEVDGEVVHRSTGAAILGDPWRALSLLSEHLERHGRSLPAGSLVLAGALTDAVPLQAG
EEEEECCEEEECCCCCEEECCHHHHHHHHHHHHHHHCCCCCCCCEEEEHHHHHHHCCCCC
SRYRLSVEGLGTITVGPTA
CEEEEEECCCEEEEECCCC
>Mature Secondary Structure
MNPRHAADLLRAARVEHRTLSPFTDEHPELDEDWGYAVQALALDDRVAAGDPVVGAKLGL
CCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCC
TSRAKQERMGVDRPIVGFLTRSMLLEPDGVGDSLEHWAQPRIEPEIAFVTGRAIDRALDA
CHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCHHHHHHCCCCCCCEEEEEECHHHHHHCCH
DEVRAGVASVGVAAEILDSRWTGYRFRLPDVVADETSAAGVLLGASPVPWPADLDLASAR
HHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHCCCCCCCEEEECCCCCCCCCCCCCCCCE
CEVEVDGEVVHRSTGAAILGDPWRALSLLSEHLERHGRSLPAGSLVLAGALTDAVPLQAG
EEEEECCEEEECCCCCEEECCHHHHHHHHHHHHHHHCCCCCCCCEEEEHHHHHHHCCCCC
SRYRLSVEGLGTITVGPTA
CEEEEEECCCEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA