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The map label for this gene is cobC [C]

Identifier: 119716247

GI number: 119716247

Start: 2157505

End: 2158710

Strand: Direct

Name: cobC [C]

Synonym: Noca_2015

Alternate gene names: 119716247

Gene position: 2157505-2158710 (Clockwise)

Preceding gene: 119716246

Following gene: 119716249

Centisome position: 43.27

GC content: 73.88

Gene sequence:

>1206_bases
GTGACCAGAAGCGTCGTCGTCGAGGCGGACGGCGGATCGCGCGGCAACCCCGGCCCGGCGGCGTACGGCGCCGTCCTCCG
TGACGCCGAGACCGGCGCGGTGATCGCCGAGGACGCCACCGCGATCGGGATCGCCTCGAACAACGTCGCGGAGTACTCCG
GGCTGATCGCCGGGCTGCGGCTCGCCGAGCGGTTCGCGCCGGACGCCGACATCGAGGTCCGGATGGACTCCAAGCTCGTG
GTCGAGCAGATGTCCGGGCGCTGGAAGATCAAGCACCCCGACATGCGGCCGCTGGCGACCGAGGCGAGCCGGCTGGCCCC
GTTCGGGACGACGTACACCTGGGTGCCGCGCGAGCAGAACAAGCACGCCGACCGGCTCGCCAACGAGGCGCTCGACGGCT
TGCGCAGCGGTGTCTCGGTGCCCGCCGAGGCGGCCGAACCCGACTCGCTGATCGAGGAGGTCGAGTCACCGGAGGAGCGG
GCGGAGGCCGGTCAGGAGCAGCCCGCGTCGATCCAGAGCCAGGCCCGAGGGTGGGGCGGCGGGGGGACGCCGACGACGGT
GGTGCTGGTCCGCCACGGGGTCACCCCGCACACGACCGAGAAGCGCTTCTCGGGCGGCCTCGCCAGCGCCAACCCGGGCC
TGAGCGAGGAAGGCCGGGCGCAGGTGCGCGCCGTCGCCGACTGGCTCGCCCCGCTCGCCGAGCGGGTGGACGTCGTGCTC
TCCTCCCCGGTGCGGCGCACCCGGGAGTCCGCGGAGCTCGTCGCCGAGCGGCTCGGTCAGGAGGTCCGGGTCGAGCCCGG
GTTCGCCGAGATGGAGTTCGGCGCCTGGGACGGGCTGACCTTCGCCGAGGTGGGGGAGCGGCACCCCGAGGATCTCACGG
CGTGGCTGGGCTCCCTCGACGTCGCGCCCGGTGGCCCGCAGGGCGGTGGGGAGTCGTTCCGCGTGGTGCAGGAGCGGGTC
CTCGCGGGTCTGAGCCGACTGCTCGACGAGCACGCCGGCCGCACCGTCGTGGTCGTCAGCCACGTCACGCCGATCAAGAC
CCTGGTCGCCCACGCCCTCGACGCCCCGCTGGAGGCGGTGTTCCGGATGGAGCTCACCCCCGCGTCGGTGACCGTCGTGT
CCTACTACGACGACCGCCCGTCGCTGCGGATGTACAACGCGCTGCCGCCCGGCAACGACGTCTTCGGCGCCGCCAGCACC
TGGTAG

Upstream 100 bases:

>100_bases
ACAACGCCGAGCTCGCGGTGATCAAGGCGGCACCGGCCGACGAGGTGATCCGCTGCGAGGAGTGCCAGCGGATTCTGGTG
CGGACGCCCGAGTCCGGCCT

Downstream 100 bases:

>100_bases
CCGCCGACGCAGTCGCCCGGACTTCTCAGGCAGAACCGGAACTGTTGGGCCGAAGTTTCGGGCCAACAGTTCCGGTTTCC
CCGGTGAACCGGGGAAACCG

Product: phosphoglycerate mutase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 401; Mature: 400

Protein sequence:

>401_residues
MTRSVVVEADGGSRGNPGPAAYGAVLRDAETGAVIAEDATAIGIASNNVAEYSGLIAGLRLAERFAPDADIEVRMDSKLV
VEQMSGRWKIKHPDMRPLATEASRLAPFGTTYTWVPREQNKHADRLANEALDGLRSGVSVPAEAAEPDSLIEEVESPEER
AEAGQEQPASIQSQARGWGGGGTPTTVVLVRHGVTPHTTEKRFSGGLASANPGLSEEGRAQVRAVADWLAPLAERVDVVL
SSPVRRTRESAELVAERLGQEVRVEPGFAEMEFGAWDGLTFAEVGERHPEDLTAWLGSLDVAPGGPQGGGESFRVVQERV
LAGLSRLLDEHAGRTVVVVSHVTPIKTLVAHALDAPLEAVFRMELTPASVTVVSYYDDRPSLRMYNALPPGNDVFGAAST
W

Sequences:

>Translated_401_residues
MTRSVVVEADGGSRGNPGPAAYGAVLRDAETGAVIAEDATAIGIASNNVAEYSGLIAGLRLAERFAPDADIEVRMDSKLV
VEQMSGRWKIKHPDMRPLATEASRLAPFGTTYTWVPREQNKHADRLANEALDGLRSGVSVPAEAAEPDSLIEEVESPEER
AEAGQEQPASIQSQARGWGGGGTPTTVVLVRHGVTPHTTEKRFSGGLASANPGLSEEGRAQVRAVADWLAPLAERVDVVL
SSPVRRTRESAELVAERLGQEVRVEPGFAEMEFGAWDGLTFAEVGERHPEDLTAWLGSLDVAPGGPQGGGESFRVVQERV
LAGLSRLLDEHAGRTVVVVSHVTPIKTLVAHALDAPLEAVFRMELTPASVTVVSYYDDRPSLRMYNALPPGNDVFGAAST
W
>Mature_400_residues
TRSVVVEADGGSRGNPGPAAYGAVLRDAETGAVIAEDATAIGIASNNVAEYSGLIAGLRLAERFAPDADIEVRMDSKLVV
EQMSGRWKIKHPDMRPLATEASRLAPFGTTYTWVPREQNKHADRLANEALDGLRSGVSVPAEAAEPDSLIEEVESPEERA
EAGQEQPASIQSQARGWGGGGTPTTVVLVRHGVTPHTTEKRFSGGLASANPGLSEEGRAQVRAVADWLAPLAERVDVVLS
SPVRRTRESAELVAERLGQEVRVEPGFAEMEFGAWDGLTFAEVGERHPEDLTAWLGSLDVAPGGPQGGGESFRVVQERVL
AGLSRLLDEHAGRTVVVVSHVTPIKTLVAHALDAPLEAVFRMELTPASVTVVSYYDDRPSLRMYNALPPGNDVFGAASTW

Specific function: Converts N1-(5-Phospho-Alpha-D-Ribosyl)-5,6- Dimethylbenzimidazole Into N1-Alpha-D-Ribosyl-5,6- Dimethylbenzimidazole; Involved In The Assembly Of The Nucleotide Loop Of Cobalamin. [C]

COG id: COG0328

COG function: function code L; Ribonuclease HI

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 RNase H domain [H]

Homologues:

Organism=Escherichia coli, GI1786857, Length=203, Percent_Identity=25.615763546798, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013078
- InterPro:   IPR012337
- InterPro:   IPR014636
- InterPro:   IPR002156 [H]

Pfam domain/function: PF00300 PGAM; PF00075 RnaseH [H]

EC number: 3.1.3.73 [C]

Molecular weight: Translated: 42748; Mature: 42617

Theoretical pI: Translated: 4.62; Mature: 4.62

Prosite motif: PS50879 RNASE_H

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRSVVVEADGGSRGNPGPAAYGAVLRDAETGAVIAEDATAIGIASNNVAEYSGLIAGLR
CCCEEEEECCCCCCCCCCHHHHHHHHHCCCCCEEEECCCCEEEECCCCHHHHHHHHHHHH
LAERFAPDADIEVRMDSKLVVEQMSGRWKIKHPDMRPLATEASRLAPFGTTYTWVPREQN
HHHHHCCCCCEEEEECHHHHHHHHCCCEEECCCCCCCHHHHHHHCCCCCCCEEECCCCCC
KHADRLANEALDGLRSGVSVPAEAAEPDSLIEEVESPEERAEAGQEQPASIQSQARGWGG
HHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCHHHHHHCCCCCCCHHHHHHCCCCC
GGTPTTVVLVRHGVTPHTTEKRFSGGLASANPGLSEEGRAQVRAVADWLAPLAERVDVVL
CCCCEEEEEEECCCCCCCCHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
SSPVRRTRESAELVAERLGQEVRVEPGFAEMEFGAWDGLTFAEVGERHPEDLTAWLGSLD
HCHHHHHHHHHHHHHHHCCCCEEECCCCCEEECCCCCCCCHHHHHCCCHHHHHHHHHCCC
VAPGGPQGGGESFRVVQERVLAGLSRLLDEHAGRTVVVVSHVTPIKTLVAHALDAPLEAV
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHCCHHHHH
FRMELTPASVTVVSYYDDRPSLRMYNALPPGNDVFGAASTW
HHEECCCCEEEEEEEECCCCCEEEEECCCCCCCCCCCCCCC
>Mature Secondary Structure 
TRSVVVEADGGSRGNPGPAAYGAVLRDAETGAVIAEDATAIGIASNNVAEYSGLIAGLR
CCEEEEECCCCCCCCCCHHHHHHHHHCCCCCEEEECCCCEEEECCCCHHHHHHHHHHHH
LAERFAPDADIEVRMDSKLVVEQMSGRWKIKHPDMRPLATEASRLAPFGTTYTWVPREQN
HHHHHCCCCCEEEEECHHHHHHHHCCCEEECCCCCCCHHHHHHHCCCCCCCEEECCCCCC
KHADRLANEALDGLRSGVSVPAEAAEPDSLIEEVESPEERAEAGQEQPASIQSQARGWGG
HHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCHHHHHHCCCCCCCHHHHHHCCCCC
GGTPTTVVLVRHGVTPHTTEKRFSGGLASANPGLSEEGRAQVRAVADWLAPLAERVDVVL
CCCCEEEEEEECCCCCCCCHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
SSPVRRTRESAELVAERLGQEVRVEPGFAEMEFGAWDGLTFAEVGERHPEDLTAWLGSLD
HCHHHHHHHHHHHHHHHCCCCEEECCCCCEEECCCCCCCCHHHHHCCCHHHHHHHHHCCC
VAPGGPQGGGESFRVVQERVLAGLSRLLDEHAGRTVVVVSHVTPIKTLVAHALDAPLEAV
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHCCHHHHH
FRMELTPASVTVVSYYDDRPSLRMYNALPPGNDVFGAASTW
HHEECCCCEEEEEEEECCCCCEEEEECCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]