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The map label for this gene is etfA [H]

Identifier: 119716050

GI number: 119716050

Start: 1936809

End: 1937762

Strand: Direct

Name: etfA [H]

Synonym: Noca_1816

Alternate gene names: 119716050

Gene position: 1936809-1937762 (Clockwise)

Preceding gene: 119716049

Following gene: 119716052

Centisome position: 38.85

GC content: 70.23

Gene sequence:

>954_bases
GTGTCTGAAGTTCTCGTTCTCATCGACCACGTCGACGGTGCCGTCCGCAAGCCGACGTACGAGCTCCTGACCATCGCCAA
GCGGCTCGGCGAGCCCTCGGCGGTCTTCATCGGCAGCGGCGCCCAGGGCGCCGAGGTGGCCGAGAAGGTCAAGGCGTACG
GCGCGGCGAAGGTCTACGTCGTCGACGACGCCCAGATCAAGGGCTACTTGGTGGCGCCCAAGGCCGAGGCCCTCCAGCAG
CTGGTGGAGAAGACCTCGCCGGCGGCGGTCCTGATCTCCTCCACCTCCGAGGGCAAGGAGATCGCCGGTCGCCTCGCGGT
CAAGATCGAGTCAGGTCTGATCACGGACGCGGTCGACGTGGAGGCCGACGGCACCGCGACCCAGTCGGTGTTCGCGGGCA
ACTACACCCTGAAGGCCAAGGTCACGAAGGGCACCCCGATCATCACGGTCAAGCCGAACTCCGCCGCGCCGGAGGAGGCC
GCCGGTGCCGGGACGGTCGAGGAGTTCGCCGCGACCGTGTCCGACGCCGCGAAGGCCGCGCAGATCGTGGCGTCGCAGCC
GCGCAAGGCGACCGGGCGCCCCGAGCTGACCGAGGCCGCGATCGTGGTCGCCGGCGGTCGCGGCACGGGCGGCAGCTTCG
AGTCCGTCGAGGGCCTCGCCGACGCCCTGGGCGGCGCGGTCGGCGCCTCGCGTGCGGCCGTCGACTCCGGCTGGATCCCG
CACACCTTCCAGATCGGGCAGACCGGCAAGACCGTCTCGCCGCAGCTCTACATCGCCACCGGCATCTCCGGCGCCATCCA
GCACCGGGCCGGCATGCAGACCTCCAAGACGATCGTCGCGGTCAACAAGGACGAGGAGGCGCCGATCTTCGAGCTGGTCG
ACTTCGGCGTGGTGGGCGACCTGCACACCGTCCTTCCGGCCCTCACCGAGGAAGTCACCAAGCGCAAGGGCTGA

Upstream 100 bases:

>100_bases
GATCGTCAAGGACGAGGACGGCTCGGGCGCCACGGCGCTCGCCGAGTTCCTCGCCGCCAAGAAATTCATCTGAGCGAAGT
TCATCTGAGGAGCTGACCAA

Downstream 100 bases:

>100_bases
GTGAGCGCAGCCGTCCACGTCGACCCGTCCGGAGCCCTCCGGGCGGGTCGACGTGACTCTCCGTCGATCCGGGACTTCCG
ACTCGACCGGGAGGGGTCAA

Product: electron transfer flavoprotein subunit alpha

Products: NA

Alternate protein names: Alpha-ETF; Electron transfer flavoprotein large subunit; ETFLS [H]

Number of amino acids: Translated: 317; Mature: 316

Protein sequence:

>317_residues
MSEVLVLIDHVDGAVRKPTYELLTIAKRLGEPSAVFIGSGAQGAEVAEKVKAYGAAKVYVVDDAQIKGYLVAPKAEALQQ
LVEKTSPAAVLISSTSEGKEIAGRLAVKIESGLITDAVDVEADGTATQSVFAGNYTLKAKVTKGTPIITVKPNSAAPEEA
AGAGTVEEFAATVSDAAKAAQIVASQPRKATGRPELTEAAIVVAGGRGTGGSFESVEGLADALGGAVGASRAAVDSGWIP
HTFQIGQTGKTVSPQLYIATGISGAIQHRAGMQTSKTIVAVNKDEEAPIFELVDFGVVGDLHTVLPALTEEVTKRKG

Sequences:

>Translated_317_residues
MSEVLVLIDHVDGAVRKPTYELLTIAKRLGEPSAVFIGSGAQGAEVAEKVKAYGAAKVYVVDDAQIKGYLVAPKAEALQQ
LVEKTSPAAVLISSTSEGKEIAGRLAVKIESGLITDAVDVEADGTATQSVFAGNYTLKAKVTKGTPIITVKPNSAAPEEA
AGAGTVEEFAATVSDAAKAAQIVASQPRKATGRPELTEAAIVVAGGRGTGGSFESVEGLADALGGAVGASRAAVDSGWIP
HTFQIGQTGKTVSPQLYIATGISGAIQHRAGMQTSKTIVAVNKDEEAPIFELVDFGVVGDLHTVLPALTEEVTKRKG
>Mature_316_residues
SEVLVLIDHVDGAVRKPTYELLTIAKRLGEPSAVFIGSGAQGAEVAEKVKAYGAAKVYVVDDAQIKGYLVAPKAEALQQL
VEKTSPAAVLISSTSEGKEIAGRLAVKIESGLITDAVDVEADGTATQSVFAGNYTLKAKVTKGTPIITVKPNSAAPEEAA
GAGTVEEFAATVSDAAKAAQIVASQPRKATGRPELTEAAIVVAGGRGTGGSFESVEGLADALGGAVGASRAAVDSGWIPH
TFQIGQTGKTVSPQLYIATGISGAIQHRAGMQTSKTIVAVNKDEEAPIFELVDFGVVGDLHTVLPALTEEVTKRKG

Specific function: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) [H]

COG id: COG2025

COG function: function code C; Electron transfer flavoprotein, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ETF alpha-subunit/fixB family [H]

Homologues:

Organism=Homo sapiens, GI4503607, Length=317, Percent_Identity=38.801261829653, Blast_Score=195, Evalue=4e-50,
Organism=Homo sapiens, GI189181759, Length=271, Percent_Identity=40.9594095940959, Blast_Score=184, Evalue=7e-47,
Organism=Escherichia coli, GI1787990, Length=285, Percent_Identity=32.9824561403509, Blast_Score=131, Evalue=6e-32,
Organism=Escherichia coli, GI1786226, Length=305, Percent_Identity=30.8196721311475, Blast_Score=118, Evalue=5e-28,
Organism=Escherichia coli, GI87082157, Length=238, Percent_Identity=27.7310924369748, Blast_Score=81, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI17506929, Length=315, Percent_Identity=39.3650793650794, Blast_Score=197, Evalue=4e-51,
Organism=Saccharomyces cerevisiae, GI6325261, Length=318, Percent_Identity=35.5345911949685, Blast_Score=153, Evalue=4e-38,
Organism=Drosophila melanogaster, GI17136898, Length=312, Percent_Identity=39.7435897435897, Blast_Score=204, Evalue=6e-53,
Organism=Drosophila melanogaster, GI24652801, Length=312, Percent_Identity=39.7435897435897, Blast_Score=204, Evalue=6e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001308
- InterPro:   IPR014730
- InterPro:   IPR014731
- InterPro:   IPR018206
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01012 ETF; PF00766 ETF_alpha [H]

EC number: NA

Molecular weight: Translated: 32418; Mature: 32287

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: PS00696 ETF_ALPHA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
0.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
0.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEVLVLIDHVDGAVRKPTYELLTIAKRLGEPSAVFIGSGAQGAEVAEKVKAYGAAKVYV
CCCEEEEEECCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHCCCEEEEE
VDDAQIKGYLVAPKAEALQQLVEKTSPAAVLISSTSEGKEIAGRLAVKIESGLITDAVDV
EECCCCCEEEECCHHHHHHHHHHCCCCCEEEEECCCCCHHHHCEEEEEEECCCEECEEEE
EADGTATQSVFAGNYTLKAKVTKGTPIITVKPNSAAPEEAAGAGTVEEFAATVSDAAKAA
CCCCCCCCEEEECCEEEEEEEECCCEEEEECCCCCCCHHHCCCCCHHHHHHHHHHHHHHH
QIVASQPRKATGRPELTEAAIVVAGGRGTGGSFESVEGLADALGGAVGASRAAVDSGWIP
HHHHCCCCCCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCHHHHCCCCCC
HTFQIGQTGKTVSPQLYIATGISGAIQHRAGMQTSKTIVAVNKDEEAPIFELVDFGVVGD
CEEEECCCCCCCCCEEEEEECCCHHHHHHCCCCCCCEEEEECCCCCCCHHHHHHHCCCCH
LHTVLPALTEEVTKRKG
HHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SEVLVLIDHVDGAVRKPTYELLTIAKRLGEPSAVFIGSGAQGAEVAEKVKAYGAAKVYV
CCEEEEEECCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHCCCEEEEE
VDDAQIKGYLVAPKAEALQQLVEKTSPAAVLISSTSEGKEIAGRLAVKIESGLITDAVDV
EECCCCCEEEECCHHHHHHHHHHCCCCCEEEEECCCCCHHHHCEEEEEEECCCEECEEEE
EADGTATQSVFAGNYTLKAKVTKGTPIITVKPNSAAPEEAAGAGTVEEFAATVSDAAKAA
CCCCCCCCEEEECCEEEEEEEECCCEEEEECCCCCCCHHHCCCCCHHHHHHHHHHHHHHH
QIVASQPRKATGRPELTEAAIVVAGGRGTGGSFESVEGLADALGGAVGASRAAVDSGWIP
HHHHCCCCCCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCHHHHCCCCCC
HTFQIGQTGKTVSPQLYIATGISGAIQHRAGMQTSKTIVAVNKDEEAPIFELVDFGVVGD
CEEEECCCCCCCCCEEEEEECCCHHHHHHCCCCCCCEEEEECCCCCCCHHHHHHHCCCCH
LHTVLPALTEEVTKRKG
HHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]