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The map label for this gene is apr [H]

Identifier: 119716022

GI number: 119716022

Start: 1899776

End: 1901683

Strand: Reverse

Name: apr [H]

Synonym: Noca_1788

Alternate gene names: 119716022

Gene position: 1901683-1899776 (Counterclockwise)

Preceding gene: 119716025

Following gene: 119716017

Centisome position: 38.14

GC content: 74.58

Gene sequence:

>1908_bases
ATGCCATCCTCGCGCACCCGGCTGCTCGCGCTCACCAGCGCCCTCGCGGCCGTCCTCTCCCTCACCGGCGTCGCCTCCGC
GGCGGCGCCGGCGGCACCTGCGGCCGCCACGGTCGGCTCCGACCTCCAGGGCGCGCACCGCGGCCTGGACCGCCTGCTCG
CCGACGGTACGCCGAACCACCGGGCGATCGTCACGTTCGCCGCCGTGCCGACCAGCACCCAGATCGGCGCGCTGCAGGCC
CTCGGCCTCGTCGTGCAGCCGATGTCCCACCTGCCGCTCGCCCTCGTCGAGGGCCCGGTGCCCGCGATGGTGCAGGCGGT
CACGGCCGGCATCGGCCTCGACGTCTACCCCGACGAGCGGCTCCAGCTCCTCGACACCCCGTCGACCAACGCGATGTCGT
CGAGCCCGGCGGCGGCCCAGGCCCTGCGCACCCGCGGCTTCACCGGCAAGGGCGTGACCGTCGGCGTCGTCGACTCCGGC
TGCGACGCGACGCACTCCGACCTCGCCGACCACGTCGTGCACAACGTGAGCCTGCTCAGCCCCGAGTACGCCAACGCCGG
CACCGACCCGGCGATCGTCGTACCCGTCGACCAGGGCCCGGTGAGCAACACCGACCTCGGCAGCGGCCACGGGACGCACG
TCGCGGGCATCATCGCCGCCGACTCCTCCTCGGCCGAGGACGGCAGTCGGTACGGCGTCGCCCCGGACGCCGACCTCGCC
TGCTTCGCGATCGGCGCAGTGCTGTTCACGACCGCGGTCGTCACCGCCTACGACTACATGCTCGACCAGCCGGACCTGCT
CGGCATCGACGTCGTCAACAACTCCTGGGGCAACAGCTACCGCCAGTTCGACCCCGCCGACCCGGTCGCCGTCGCCACCA
AGGCCGTGGCCGACCGTGGCGTGACCGTGGTGTTCGCCGCCGGCAACTCCGGCAGCGGCGACGTCCCGATGAGCCTGAAC
CCGTTCTCCCAGTCGCCCTGGGTGATCTCCGTGGCGGCCGGCACCCTGGACCGGCACCGCGGCGACTTCTCCTCCAACGG
CCTGGTCCACGACAACTCGCAACCCACGGCCATCGGCACCGAGGGACACACCACCTACACCGGCGACCGGATCGGGCTGG
TGCACCCGGACCTCACCGCCCCCGGCGTCGACATCGGCTCGACCTGCGACAGCGCCGGCACCCTGATCGGGCCGTGCGGA
CCGGACGAGAACGCCTCGGCCTCGGGCACCTCGATGGCCTCGCCGCACATCGCCGGCGCGGCCGCGGTGCTGCTGCAGGC
CCAGCCCCGGCTCAGCCCGGAGCAGGTGCGGCTCGCCCTGCAGGCGACGGCGACGCCGGTCCAGGCGACGGGCGGCCCGG
CCGCGCTGCCGTTCTGGGAGGTCGGGTACGGCTACGCCAACCTCGACCGCGCGGTCCAGCTGGTGCGCTCCGACGGCTGG
CAGGGGCGGCTGCGTGCCGCCGCCCACCGGGCGGACCGCCGGGTGCTCGCCGCGGACGGCACCGCGGTCGTCCGATCCGA
CTTCTTCGTCCACGAGGCGCCCCCGGCGACCGCGGGCGGCAGTGACAGCGCGTCGTACGACGTGCCCGTGTCCGCGCGCA
CCCGCGGGCTCGCCGTGAGCCTGGCGTTCCCGTCCGGCGGCAGCGTCGGCGCCAGCCTGTTCAGCTACACCGTGCAGGTC
CTCGACCCCAGCGGGAAGGTGATCGCGACGACCACTTCGGACCCGGTCGCGGGCTCGGGCACCGCGCTGGCGACGGTCCG
GCTGCCCCAGGGCGCGGAGGCCGGGACGTACACGTTCGAGGTCACCGGCGACTACGCCGCCTCCGACCCGGACACCGTCG
ACAGCGACTCGCTGCTGGGCCGGTTCGTCACCCTGCACGTGGCCCAGCTGCGGAGCAGCCGGCGCTAG

Upstream 100 bases:

>100_bases
AGCAGGTCGACCAGAAGCAGCGCGACCAGAAGCCGGGCGACGACGTAACCCGCCGCGCGGTTGCGGCGTTGTCCGGGCAC
CTCACGAGATCGGATCATCC

Downstream 100 bases:

>100_bases
GAGAGGGCCCCTCGAGACGGCAGGGCCCTCAAGTGCCGCGTCCCACAAGTTCTTGGGCGCTTCGCGCCCACATGGCACGC
GCCTCGCTGCGTTGCCGACG

Product: peptidase S8/S53 subtilisin kexin sedolisin

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 635; Mature: 634

Protein sequence:

>635_residues
MPSSRTRLLALTSALAAVLSLTGVASAAAPAAPAAATVGSDLQGAHRGLDRLLADGTPNHRAIVTFAAVPTSTQIGALQA
LGLVVQPMSHLPLALVEGPVPAMVQAVTAGIGLDVYPDERLQLLDTPSTNAMSSSPAAAQALRTRGFTGKGVTVGVVDSG
CDATHSDLADHVVHNVSLLSPEYANAGTDPAIVVPVDQGPVSNTDLGSGHGTHVAGIIAADSSSAEDGSRYGVAPDADLA
CFAIGAVLFTTAVVTAYDYMLDQPDLLGIDVVNNSWGNSYRQFDPADPVAVATKAVADRGVTVVFAAGNSGSGDVPMSLN
PFSQSPWVISVAAGTLDRHRGDFSSNGLVHDNSQPTAIGTEGHTTYTGDRIGLVHPDLTAPGVDIGSTCDSAGTLIGPCG
PDENASASGTSMASPHIAGAAAVLLQAQPRLSPEQVRLALQATATPVQATGGPAALPFWEVGYGYANLDRAVQLVRSDGW
QGRLRAAAHRADRRVLAADGTAVVRSDFFVHEAPPATAGGSDSASYDVPVSARTRGLAVSLAFPSGGSVGASLFSYTVQV
LDPSGKVIATTTSDPVAGSGTALATVRLPQGAEAGTYTFEVTGDYAASDPDTVDSDSLLGRFVTLHVAQLRSSRR

Sequences:

>Translated_635_residues
MPSSRTRLLALTSALAAVLSLTGVASAAAPAAPAAATVGSDLQGAHRGLDRLLADGTPNHRAIVTFAAVPTSTQIGALQA
LGLVVQPMSHLPLALVEGPVPAMVQAVTAGIGLDVYPDERLQLLDTPSTNAMSSSPAAAQALRTRGFTGKGVTVGVVDSG
CDATHSDLADHVVHNVSLLSPEYANAGTDPAIVVPVDQGPVSNTDLGSGHGTHVAGIIAADSSSAEDGSRYGVAPDADLA
CFAIGAVLFTTAVVTAYDYMLDQPDLLGIDVVNNSWGNSYRQFDPADPVAVATKAVADRGVTVVFAAGNSGSGDVPMSLN
PFSQSPWVISVAAGTLDRHRGDFSSNGLVHDNSQPTAIGTEGHTTYTGDRIGLVHPDLTAPGVDIGSTCDSAGTLIGPCG
PDENASASGTSMASPHIAGAAAVLLQAQPRLSPEQVRLALQATATPVQATGGPAALPFWEVGYGYANLDRAVQLVRSDGW
QGRLRAAAHRADRRVLAADGTAVVRSDFFVHEAPPATAGGSDSASYDVPVSARTRGLAVSLAFPSGGSVGASLFSYTVQV
LDPSGKVIATTTSDPVAGSGTALATVRLPQGAEAGTYTFEVTGDYAASDPDTVDSDSLLGRFVTLHVAQLRSSRR
>Mature_634_residues
PSSRTRLLALTSALAAVLSLTGVASAAAPAAPAAATVGSDLQGAHRGLDRLLADGTPNHRAIVTFAAVPTSTQIGALQAL
GLVVQPMSHLPLALVEGPVPAMVQAVTAGIGLDVYPDERLQLLDTPSTNAMSSSPAAAQALRTRGFTGKGVTVGVVDSGC
DATHSDLADHVVHNVSLLSPEYANAGTDPAIVVPVDQGPVSNTDLGSGHGTHVAGIIAADSSSAEDGSRYGVAPDADLAC
FAIGAVLFTTAVVTAYDYMLDQPDLLGIDVVNNSWGNSYRQFDPADPVAVATKAVADRGVTVVFAAGNSGSGDVPMSLNP
FSQSPWVISVAAGTLDRHRGDFSSNGLVHDNSQPTAIGTEGHTTYTGDRIGLVHPDLTAPGVDIGSTCDSAGTLIGPCGP
DENASASGTSMASPHIAGAAAVLLQAQPRLSPEQVRLALQATATPVQATGGPAALPFWEVGYGYANLDRAVQLVRSDGWQ
GRLRAAAHRADRRVLAADGTAVVRSDFFVHEAPPATAGGSDSASYDVPVSARTRGLAVSLAFPSGGSVGASLFSYTVQVL
DPSGKVIATTTSDPVAGSGTALATVRLPQGAEAGTYTFEVTGDYAASDPDTVDSDSLLGRFVTLHVAQLRSSRR

Specific function: Subtilisin is an extracellular alkaline serine protease, it catalyzes the hydrolysis of proteins and peptide amides [H]

COG id: COG1404

COG function: function code O; Subtilisin-like serine proteases

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S8 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000209
- InterPro:   IPR022398
- InterPro:   IPR015500 [H]

Pfam domain/function: PF00082 Peptidase_S8 [H]

EC number: =3.4.21.62 [H]

Molecular weight: Translated: 64385; Mature: 64254

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: PS00136 SUBTILASE_ASP ; PS00137 SUBTILASE_HIS ; PS00138 SUBTILASE_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSSRTRLLALTSALAAVLSLTGVASAAAPAAPAAATVGSDLQGAHRGLDRLLADGTPNH
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCCHHHHHHHHHHHHHCCCCCC
RAIVTFAAVPTSTQIGALQALGLVVQPMSHLPLALVEGPVPAMVQAVTAGIGLDVYPDER
EEEEEEEECCCCCCHHHHHHHHHHHCCHHHCCEEEECCCHHHHHHHHHHCCCCCCCCCCC
LQLLDTPSTNAMSSSPAAAQALRTRGFTGKGVTVGVVDSGCDATHSDLADHVVHNVSLLS
EEEEECCCCCCCCCCCHHHHHHHHCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCC
PEYANAGTDPAIVVPVDQGPVSNTDLGSGHGTHVAGIIAADSSSAEDGSRYGVAPDADLA
CCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCHH
CFAIGAVLFTTAVVTAYDYMLDQPDLLGIDVVNNSWGNSYRQFDPADPVAVATKAVADRG
HHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHCCC
VTVVFAAGNSGSGDVPMSLNPFSQSPWVISVAAGTLDRHRGDFSSNGLVHDNSQPTAIGT
EEEEEECCCCCCCCCCEEECCCCCCCEEEEEECCCHHHHCCCCCCCCEEECCCCCCEECC
EGHTTYTGDRIGLVHPDLTAPGVDIGSTCDSAGTLIGPCGPDENASASGTSMASPHIAGA
CCCEEECCCEEEEECCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCHHHH
AAVLLQAQPRLSPEQVRLALQATATPVQATGGPAALPFWEVGYGYANLDRAVQLVRSDGW
HEEEEECCCCCCHHHEEEEEEECCCCEECCCCCCCCCHHHCCCCHHHHHHHHHHHHCCCC
QGRLRAAAHRADRRVLAADGTAVVRSDFFVHEAPPATAGGSDSASYDVPVSARTRGLAVS
CHHHHHHHHHCCCEEEEECCCEEEECCEEEECCCCCCCCCCCCCCEECCCCCCCCCEEEE
LAFPSGGSVGASLFSYTVQVLDPSGKVIATTTSDPVAGSGTALATVRLPQGAEAGTYTFE
EECCCCCCHHHHHHHEEEEEECCCCCEEEEECCCCCCCCCCEEEEEECCCCCCCCEEEEE
VTGDYAASDPDTVDSDSLLGRFVTLHVAQLRSSRR
EECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
PSSRTRLLALTSALAAVLSLTGVASAAAPAAPAAATVGSDLQGAHRGLDRLLADGTPNH
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCCHHHHHHHHHHHHHCCCCCC
RAIVTFAAVPTSTQIGALQALGLVVQPMSHLPLALVEGPVPAMVQAVTAGIGLDVYPDER
EEEEEEEECCCCCCHHHHHHHHHHHCCHHHCCEEEECCCHHHHHHHHHHCCCCCCCCCCC
LQLLDTPSTNAMSSSPAAAQALRTRGFTGKGVTVGVVDSGCDATHSDLADHVVHNVSLLS
EEEEECCCCCCCCCCCHHHHHHHHCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCC
PEYANAGTDPAIVVPVDQGPVSNTDLGSGHGTHVAGIIAADSSSAEDGSRYGVAPDADLA
CCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCHH
CFAIGAVLFTTAVVTAYDYMLDQPDLLGIDVVNNSWGNSYRQFDPADPVAVATKAVADRG
HHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHCCC
VTVVFAAGNSGSGDVPMSLNPFSQSPWVISVAAGTLDRHRGDFSSNGLVHDNSQPTAIGT
EEEEEECCCCCCCCCCEEECCCCCCCEEEEEECCCHHHHCCCCCCCCEEECCCCCCEECC
EGHTTYTGDRIGLVHPDLTAPGVDIGSTCDSAGTLIGPCGPDENASASGTSMASPHIAGA
CCCEEECCCEEEEECCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCHHHH
AAVLLQAQPRLSPEQVRLALQATATPVQATGGPAALPFWEVGYGYANLDRAVQLVRSDGW
HEEEEECCCCCCHHHEEEEEEECCCCEECCCCCCCCCHHHCCCCHHHHHHHHHHHHCCCC
QGRLRAAAHRADRRVLAADGTAVVRSDFFVHEAPPATAGGSDSASYDVPVSARTRGLAVS
CHHHHHHHHHCCCEEEEECCCEEEECCEEEECCCCCCCCCCCCCCEECCCCCCCCCEEEE
LAFPSGGSVGASLFSYTVQVLDPSGKVIATTTSDPVAGSGTALATVRLPQGAEAGTYTFE
EECCCCCCHHHHHHHEEEEEECCCCCEEEEECCCCCCCCCCEEEEEECCCCCCCCEEEEE
VTGDYAASDPDTVDSDSLLGRFVTLHVAQLRSSRR
EECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 6420308; 9826175 [H]