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The map label for this gene is pleC [H]

Identifier: 119715984

GI number: 119715984

Start: 1860168

End: 1861976

Strand: Direct

Name: pleC [H]

Synonym: Noca_1749

Alternate gene names: 119715984

Gene position: 1860168-1861976 (Clockwise)

Preceding gene: 119715983

Following gene: 119715985

Centisome position: 37.31

GC content: 73.36

Gene sequence:

>1809_bases
GTGTGTGCGGGGAGTCCGTGCGTGGGGAGTCCGTGCGTGGACACTGTGGGAGTCGGCGCGTCCGTGGGGGACGCGCGAGG
GGTGTGGTCGAGCCATGAGCGAGCGCAGCGAGCGAGTACGCGCATGAGTGCGGGCCGTCCGGTCGCGCGGTTGGTCCAGC
CGGTGATCGTGCGCGTGACCGCGATGGCCGCGTTGATGGCTCTGATCGCGGTCCTCGGCGTCGTGCTGTCGACGGCGGCG
GTCAACCACCTCACCGACGACCTGCAGCCGGCGGCCGCCGCCAACCAGGACGTCTACCAGGACCTCACCGACATGTCCGC
CGCCGTGGAGTCGTGGTCGGCCTCCGGCCAGCGGGCCGCGGCCGATCGGTTCACGCAGGCACTGGTGCGGTTCCCGGCCG
ACCAGCAGAAGGTCCGCCGGTTCGCCGACGGCGACGACGAGCTGGAGATGCTGGTGACCCGCCAGGAGCGGGTCGCCCAG
GCCTGGATCGAGCGGTTCGCTCAGCCCCGGATCGACGCCGAGGGCGGGACCCCTCCCGCGGCCGGGCAGGTGCGGTCCGG
CGCCGCCGCGTTCGAGGCGGTCCGTAGCGCTCACCAGGACACCACCCAGGCCTTCGACAGCCGGGTGCGCCAGGCGCGCG
CCGACGCGTCGCTCCGCCTCAAGGGGACCGTGCTTGCCGTGGTCCTCCTCGCCGGCGCGGCCTGGTACGTGATCTCCCGC
TCCCGGCGCCGACTGATGACCGAGCTGTCCGAGCCGTTGCTGGCGCTGGAACAGGTGGTGCAGCGGATGGCCAAGCAGGA
CCACGACGTACGAGCCAAGGAGCTGGGGCCCAAGGAGGTGCGTGCGGTCGCGTCGGCGCTGAACGCCTTCGCCGACGCCC
AGGGCCGGGCCCGCGCCGTCGAGGGCCGGATCCAGAGCGAGCTGCGCAGCCTCGACACGGCGCGCGACGACTTCGTCTCC
AACGTCTCCCACGAGCTGCGCACGCCGCTGACCACGATCAGCGGCTACCTCGAGCTCGTCGCCGAGGAGTTCGAGGGCCG
GATGGATCCGCCGCACGAGCGGATGCTGGAGGCGACCCGGCGCAACGTGGCCCGCCTCAAGGCGCTGATCGACGACCTGC
TCGCCCTCTCGCGCGCCGAGGGCCGCCGCAGCGACTTCGAGCCGGTCGACCTCGCACTGCTGGTCCGGGAGGCGGTGACC
GACGTCCGCATCACCGCGGCCCGGCGCCGGATCCGCCTCGAGGTCGACACCCCCGAGGACGTCGTACCGGTGCTCGCCGA
TCGGGCCATGCTGCACCGCGCGTTGCTCAACGTGCTCAGCAACGCGGTGAAGTTCAGCCACGACGACGGCACGGTCGACG
TCGTGCTCACGGTCCTGGGCGGTCAGGTCGAGGTGCGGGTCACCGACCACGGCATCGGCATCCCGGGCGCCGAGATCGAG
CGGCTCGGCACCCGGTTCTTCCGGGCGTCGAACGCGGTGACGAACGAGATCGCCGGCACCGGGCTGGGCCTGCGGATCAC
CCAGACCATCATCGACCGCCACTCCGGCGAGGTCGTCATCGAGTCCGAGGAGGGCGAGGGCACCAGCGTCGTCGTCCGGC
TCCGTCGGCACGGCGACGGCCTGCCGCCACTGCTGCCCCACGAGATCGTGGCGGAGGAGGAGGCGCGCGCCGCCGCGCTG
CGGGCGCGCGGCGCCCGCGGTGCCGGTGTCGAGGTGGTCGACGCCGCCGACCCGGAACGCCCGGCGGGCGACACGGACGG
AACGGACGCACCGCCGCGGATCGTGCCGGCCTTCCCCCGGCGACGCTGA

Upstream 100 bases:

>100_bases
GGTGCAGGCACTGCTCACCCGTTCGGTCTGACCGAATCGGCACCGCGGGGAGCCCGGCGGCGATACGCTCCTCGGCAGGG
GTGCGGGGGGCACTCTGACG

Downstream 100 bases:

>100_bases
GCGGAGCCGCGCCAACGGTTCCGGTCCCGGCAGGGGAACAACGCGGATTACCGCGGCGTTGGGACCCGTGACACAATCGT
GTGCTGGCTCCGGTTCACGG

Product: ATPase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 602; Mature: 602

Protein sequence:

>602_residues
MCAGSPCVGSPCVDTVGVGASVGDARGVWSSHERAQRASTRMSAGRPVARLVQPVIVRVTAMAALMALIAVLGVVLSTAA
VNHLTDDLQPAAAANQDVYQDLTDMSAAVESWSASGQRAAADRFTQALVRFPADQQKVRRFADGDDELEMLVTRQERVAQ
AWIERFAQPRIDAEGGTPPAAGQVRSGAAAFEAVRSAHQDTTQAFDSRVRQARADASLRLKGTVLAVVLLAGAAWYVISR
SRRRLMTELSEPLLALEQVVQRMAKQDHDVRAKELGPKEVRAVASALNAFADAQGRARAVEGRIQSELRSLDTARDDFVS
NVSHELRTPLTTISGYLELVAEEFEGRMDPPHERMLEATRRNVARLKALIDDLLALSRAEGRRSDFEPVDLALLVREAVT
DVRITAARRRIRLEVDTPEDVVPVLADRAMLHRALLNVLSNAVKFSHDDGTVDVVLTVLGGQVEVRVTDHGIGIPGAEIE
RLGTRFFRASNAVTNEIAGTGLGLRITQTIIDRHSGEVVIESEEGEGTSVVVRLRRHGDGLPPLLPHEIVAEEEARAAAL
RARGARGAGVEVVDAADPERPAGDTDGTDAPPRIVPAFPRRR

Sequences:

>Translated_602_residues
MCAGSPCVGSPCVDTVGVGASVGDARGVWSSHERAQRASTRMSAGRPVARLVQPVIVRVTAMAALMALIAVLGVVLSTAA
VNHLTDDLQPAAAANQDVYQDLTDMSAAVESWSASGQRAAADRFTQALVRFPADQQKVRRFADGDDELEMLVTRQERVAQ
AWIERFAQPRIDAEGGTPPAAGQVRSGAAAFEAVRSAHQDTTQAFDSRVRQARADASLRLKGTVLAVVLLAGAAWYVISR
SRRRLMTELSEPLLALEQVVQRMAKQDHDVRAKELGPKEVRAVASALNAFADAQGRARAVEGRIQSELRSLDTARDDFVS
NVSHELRTPLTTISGYLELVAEEFEGRMDPPHERMLEATRRNVARLKALIDDLLALSRAEGRRSDFEPVDLALLVREAVT
DVRITAARRRIRLEVDTPEDVVPVLADRAMLHRALLNVLSNAVKFSHDDGTVDVVLTVLGGQVEVRVTDHGIGIPGAEIE
RLGTRFFRASNAVTNEIAGTGLGLRITQTIIDRHSGEVVIESEEGEGTSVVVRLRRHGDGLPPLLPHEIVAEEEARAAAL
RARGARGAGVEVVDAADPERPAGDTDGTDAPPRIVPAFPRRR
>Mature_602_residues
MCAGSPCVGSPCVDTVGVGASVGDARGVWSSHERAQRASTRMSAGRPVARLVQPVIVRVTAMAALMALIAVLGVVLSTAA
VNHLTDDLQPAAAANQDVYQDLTDMSAAVESWSASGQRAAADRFTQALVRFPADQQKVRRFADGDDELEMLVTRQERVAQ
AWIERFAQPRIDAEGGTPPAAGQVRSGAAAFEAVRSAHQDTTQAFDSRVRQARADASLRLKGTVLAVVLLAGAAWYVISR
SRRRLMTELSEPLLALEQVVQRMAKQDHDVRAKELGPKEVRAVASALNAFADAQGRARAVEGRIQSELRSLDTARDDFVS
NVSHELRTPLTTISGYLELVAEEFEGRMDPPHERMLEATRRNVARLKALIDDLLALSRAEGRRSDFEPVDLALLVREAVT
DVRITAARRRIRLEVDTPEDVVPVLADRAMLHRALLNVLSNAVKFSHDDGTVDVVLTVLGGQVEVRVTDHGIGIPGAEIE
RLGTRFFRASNAVTNEIAGTGLGLRITQTIIDRHSGEVVIESEEGEGTSVVVRLRRHGDGLPPLLPHEIVAEEEARAAAL
RARGARGAGVEVVDAADPERPAGDTDGTDAPPRIVPAFPRRR

Specific function: Member of the two-component regulatory system involved in the regulation of polar organelle development. PleC functions as a membrane-associated protein kinase that transfers phosphate to the response regulator pleD, leading to its activation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI145693157, Length=235, Percent_Identity=31.9148936170213, Blast_Score=111, Evalue=2e-25,
Organism=Escherichia coli, GI1786600, Length=230, Percent_Identity=32.6086956521739, Blast_Score=110, Evalue=3e-25,
Organism=Escherichia coli, GI1789149, Length=319, Percent_Identity=26.3322884012539, Blast_Score=102, Evalue=5e-23,
Organism=Escherichia coli, GI1788549, Length=219, Percent_Identity=29.2237442922374, Blast_Score=99, Evalue=1e-21,
Organism=Escherichia coli, GI87082128, Length=278, Percent_Identity=27.6978417266187, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI1790861, Length=317, Percent_Identity=29.9684542586751, Blast_Score=96, Evalue=8e-21,
Organism=Escherichia coli, GI1788393, Length=245, Percent_Identity=28.1632653061224, Blast_Score=94, Evalue=3e-20,
Organism=Escherichia coli, GI1790346, Length=262, Percent_Identity=28.2442748091603, Blast_Score=91, Evalue=3e-19,
Organism=Escherichia coli, GI48994928, Length=246, Percent_Identity=25.609756097561, Blast_Score=90, Evalue=4e-19,
Organism=Escherichia coli, GI1790436, Length=234, Percent_Identity=27.7777777777778, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1788713, Length=234, Percent_Identity=29.0598290598291, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1786912, Length=207, Percent_Identity=27.0531400966184, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1789808, Length=309, Percent_Identity=27.831715210356, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI1786783, Length=286, Percent_Identity=25.5244755244755, Blast_Score=75, Evalue=9e-15,
Organism=Escherichia coli, GI87081816, Length=352, Percent_Identity=26.4204545454545, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1787894, Length=234, Percent_Identity=25.2136752136752, Blast_Score=66, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 64986; Mature: 64986

Theoretical pI: Translated: 6.27; Mature: 6.27

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN ; PS00116 DNA_POLYMERASE_B

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCAGSPCVGSPCVDTVGVGASVGDARGVWSSHERAQRASTRMSAGRPVARLVQPVIVRVT
CCCCCCCCCCCCHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
AMAALMALIAVLGVVLSTAAVNHLTDDLQPAAAANQDVYQDLTDMSAAVESWSASGQRAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCHHHHHHHHHHHHHHHHHCCCCCHHH
ADRFTQALVRFPADQQKVRRFADGDDELEMLVTRQERVAQAWIERFAQPRIDAEGGTPPA
HHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
AGQVRSGAAAFEAVRSAHQDTTQAFDSRVRQARADASLRLKGTVLAVVLLAGAAWYVISR
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHH
SRRRLMTELSEPLLALEQVVQRMAKQDHDVRAKELGPKEVRAVASALNAFADAQGRARAV
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCHHHHHHHHHHHHHHHCCCCHHHHH
EGRIQSELRSLDTARDDFVSNVSHELRTPLTTISGYLELVAEEFEGRMDPPHERMLEATR
HHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
RNVARLKALIDDLLALSRAEGRRSDFEPVDLALLVREAVTDVRITAARRRIRLEVDTPED
HHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCEEEEECCCCHH
VVPVLADRAMLHRALLNVLSNAVKFSHDDGTVDVVLTVLGGQVEVRVTDHGIGIPGAEIE
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHEECCCEEEEEEECCCCCCCCHHHH
RLGTRFFRASNAVTNEIAGTGLGLRITQTIIDRHSGEVVIESEEGEGTSVVVRLRRHGDG
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCEEEECCCCCCCHHEEEEHHCCCC
LPPLLPHEIVAEEEARAAALRARGARGAGVEVVDAADPERPAGDTDGTDAPPRIVPAFPR
CCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCC
RR
CC
>Mature Secondary Structure
MCAGSPCVGSPCVDTVGVGASVGDARGVWSSHERAQRASTRMSAGRPVARLVQPVIVRVT
CCCCCCCCCCCCHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
AMAALMALIAVLGVVLSTAAVNHLTDDLQPAAAANQDVYQDLTDMSAAVESWSASGQRAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCHHHHHHHHHHHHHHHHHCCCCCHHH
ADRFTQALVRFPADQQKVRRFADGDDELEMLVTRQERVAQAWIERFAQPRIDAEGGTPPA
HHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
AGQVRSGAAAFEAVRSAHQDTTQAFDSRVRQARADASLRLKGTVLAVVLLAGAAWYVISR
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHH
SRRRLMTELSEPLLALEQVVQRMAKQDHDVRAKELGPKEVRAVASALNAFADAQGRARAV
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCHHHHHHHHHHHHHHHCCCCHHHHH
EGRIQSELRSLDTARDDFVSNVSHELRTPLTTISGYLELVAEEFEGRMDPPHERMLEATR
HHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
RNVARLKALIDDLLALSRAEGRRSDFEPVDLALLVREAVTDVRITAARRRIRLEVDTPED
HHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCEEEEECCCCHH
VVPVLADRAMLHRALLNVLSNAVKFSHDDGTVDVVLTVLGGQVEVRVTDHGIGIPGAEIE
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHEECCCEEEEEEECCCCCCCCHHHH
RLGTRFFRASNAVTNEIAGTGLGLRITQTIIDRHSGEVVIESEEGEGTSVVVRLRRHGDG
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCEEEECCCCCCCHHEEEEHHCCCC
LPPLLPHEIVAEEEARAAALRARGARGAGVEVVDAADPERPAGDTDGTDAPPRIVPAFPR
CCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCC
RR
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8421698; 11259647 [H]