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The map label for this gene is fabR [H]

Identifier: 119715965

GI number: 119715965

Start: 1838364

End: 1838969

Strand: Reverse

Name: fabR [H]

Synonym: Noca_1730

Alternate gene names: 119715965

Gene position: 1838969-1838364 (Counterclockwise)

Preceding gene: 119715967

Following gene: 119715960

Centisome position: 36.88

GC content: 72.61

Gene sequence:

>606_bases
ATGGCCCGCAAGGAGCGCACCCGGCGGGCGATCCTCGACGCGGCCCTCGAGCTGTCCTCGGAGACCACGATGGCGGCCCT
CTCCTTGCGCCAGGTGGCGAAGGAGGTCGGCATCGTGCCGACCGCGTTCTACCGGCACTTCGACTCCGTCGAGGCGCTCG
GGGTCGCGCTCGTCGACGAGTCGTTCGTGTCGCTGCGCACGATGCTGCGCGACATCCGCCGCGGCGACCCGGCCCTGGCC
GACATCGTCGACCGCTCGATCGGGATCCTGGTGGACCACGTCCACCAGCAACGCGCGCACTTCTCGTTCATCGCCCGGGA
GCGGGCCGCCGGGTTGCCGGCGGTGCGGCGCGCGATCCGGGACCAGATCGCGTTGTTCGAGCACGAGCTGGCCAGCGACC
TGGCCCGGCTGCCGGGCACCGACACGTGGTCCGCGCGCGACCTGCGGATCCTCTCCGACCTGATCGTCACGGCCATGGTC
TCCACCGCCGAAGCGATCCTGACGGCCGACGGCCCGGCCGCCGAGCAGGCGCTCGTCGAGCAGGCGCGGGTGCAGCTGCG
GATGGTGCTGATCGGCGCCCTCAACTGGCGCTCGGGCCCGGCCTGA

Upstream 100 bases:

>100_bases
GTCGGAAGGGTCGGCTCCCTCACAGGGAGACGCGCACCACTAGCCTGACGTCATGCCTGAGGTGACGGCGGGGAGCGCGG
CGGCGGAGCCGATGTCGCGC

Downstream 100 bases:

>100_bases
CCACCACTTCCGGGATCGTCGCGTCGGCCGGCAGGTCGAGCACGTGCAGGATCGTGTCGGCGACGGTCTCGGGCCGGACC
CACCGGGCGGCGTCGTACTC

Product: regulatory protein TetR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 201; Mature: 200

Protein sequence:

>201_residues
MARKERTRRAILDAALELSSETTMAALSLRQVAKEVGIVPTAFYRHFDSVEALGVALVDESFVSLRTMLRDIRRGDPALA
DIVDRSIGILVDHVHQQRAHFSFIARERAAGLPAVRRAIRDQIALFEHELASDLARLPGTDTWSARDLRILSDLIVTAMV
STAEAILTADGPAAEQALVEQARVQLRMVLIGALNWRSGPA

Sequences:

>Translated_201_residues
MARKERTRRAILDAALELSSETTMAALSLRQVAKEVGIVPTAFYRHFDSVEALGVALVDESFVSLRTMLRDIRRGDPALA
DIVDRSIGILVDHVHQQRAHFSFIARERAAGLPAVRRAIRDQIALFEHELASDLARLPGTDTWSARDLRILSDLIVTAMV
STAEAILTADGPAAEQALVEQARVQLRMVLIGALNWRSGPA
>Mature_200_residues
ARKERTRRAILDAALELSSETTMAALSLRQVAKEVGIVPTAFYRHFDSVEALGVALVDESFVSLRTMLRDIRRGDPALAD
IVDRSIGILVDHVHQQRAHFSFIARERAAGLPAVRRAIRDQIALFEHELASDLARLPGTDTWSARDLRILSDLIVTAMVS
TAEAILTADGPAAEQALVEQARVQLRMVLIGALNWRSGPA

Specific function: Represses the transcription of fabB, involved in unsaturated fatty acid (UFA) biosynthesis. By controlling UFA production, fabR directly influences the physical properties of the membrane bilayer [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH tetR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI145693209, Length=205, Percent_Identity=34.6341463414634, Blast_Score=100, Evalue=7e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR015893
- InterPro:   IPR001647 [H]

Pfam domain/function: PF00440 TetR_N [H]

EC number: NA

Molecular weight: Translated: 22086; Mature: 21955

Theoretical pI: Translated: 7.10; Mature: 7.10

Prosite motif: PS50977 HTH_TETR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARKERTRRAILDAALELSSETTMAALSLRQVAKEVGIVPTAFYRHFDSVEALGVALVDE
CCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
SFVSLRTMLRDIRRGDPALADIVDRSIGILVDHVHQQRAHFSFIARERAAGLPAVRRAIR
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
DQIALFEHELASDLARLPGTDTWSARDLRILSDLIVTAMVSTAEAILTADGPAAEQALVE
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
QARVQLRMVLIGALNWRSGPA
HHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
ARKERTRRAILDAALELSSETTMAALSLRQVAKEVGIVPTAFYRHFDSVEALGVALVDE
CCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
SFVSLRTMLRDIRRGDPALADIVDRSIGILVDHVHQQRAHFSFIARERAAGLPAVRRAIR
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
DQIALFEHELASDLARLPGTDTWSARDLRILSDLIVTAMVSTAEAILTADGPAAEQALVE
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
QARVQLRMVLIGALNWRSGPA
HHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA