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The map label for this gene is mhpF [C]

Identifier: 119715885

GI number: 119715885

Start: 1752772

End: 1753716

Strand: Reverse

Name: mhpF [C]

Synonym: Noca_1650

Alternate gene names: 119715885

Gene position: 1753716-1752772 (Counterclockwise)

Preceding gene: 119715886

Following gene: 119715884

Centisome position: 35.17

GC content: 70.79

Gene sequence:

>945_bases
GTGACTAGGACCAAGGTCGCGATCATCGGGTCCGGCAACATCGGCACCGACCTGATGATCAAGGTGCTGCGCACCAGCAA
GCACCTCGAGATGGGGGCCATGGTCGGCATCGACCCGGCCTCGGACGGGCTCGCCCGAGCCGGCCGGTTCGGTGTCCCGA
CAACGGCGGAGGGCGTCGAGGGCCTGGTCGCGCTGCCCGGCTTCGACGACATCGAGATCGTCTTCGACGCCACCTCGGCC
GGCGCGCACGTCGTGAACGCGGCCCGGCTCCTGCCCCTCGGCAAGCGCCTGATCGACCTGACCCCGGCCGCCCTCGGCCC
CTTCACGATCCCGGCGGTCAACCTCGAGGACCACCTCGAGGCACCGAACCTGAACATGGTGACCTGCGGCGGCCAGGCGA
CGATCCCGATCGTCGCGGCGATCTCGCGGGTGGTCCCGGTCGAGTACGCCGAGATCGTCGCCTCGATCGCGTCCCGGTCG
GCCGGCCCCGGCACCCGCGCCAACATCGACGAGTTCACCGAGACCACCTCGTCGGCCATCGTGGAGGTGGGGGGCGCCAC
GCGCGGCAAGGCGATCATCATCCTCAACCCGGCCGAGCCGCCGCTGATCATGCGGGACACGGTCTTCGCACTGGTCACGG
CCGCCGACCCCGACGTCCACGAACAGATCCGCGCGAGCGTCGACAAGATGGTGGCCGACGTTGCGGCCTACGTGCCCGGC
TACCGGCTCAAGCAGGCCGTCCAGGTCACGGAGATCCCGGCGGACCAGCCGGTGCACACCCTCCTCGCTCCCGACGCGGA
GCGCCCCACGCACCAGGTCTCGGTGTTCCTCGAGGTCGAGGGCGCCGCGCACTACCTCCCGGCGTACGCCGGGAACCTCG
ACATCATGACCTCCGCCGCGCTCCAGGTGGCCGAGCGGATCGCTGCAGGGAAGGCCGACCGGTGA

Upstream 100 bases:

>100_bases
GGCGCGCTCGGGCCGATGCGCCCGATCGCGCCGGGCCAGACCGTCCGTAGCACCGTGTCGGGCCTCGGCTCGGTGACCTT
CACCGTAGGGAGTGAGAACC

Downstream 100 bases:

>100_bases
ACGCACACCAGATCTTCGTCCAGGACGTCACGCTGCGCGACGGGATGCACGCCGTGCGGCACCGGATCGGGCTCGACGAC
GTGCGCCGCATCGTCGCCGC

Product: acetaldehyde dehydrogenase

Products: NA

Alternate protein names: Acetaldehyde dehydrogenase [acetylating] 1

Number of amino acids: Translated: 314; Mature: 313

Protein sequence:

>314_residues
MTRTKVAIIGSGNIGTDLMIKVLRTSKHLEMGAMVGIDPASDGLARAGRFGVPTTAEGVEGLVALPGFDDIEIVFDATSA
GAHVVNAARLLPLGKRLIDLTPAALGPFTIPAVNLEDHLEAPNLNMVTCGGQATIPIVAAISRVVPVEYAEIVASIASRS
AGPGTRANIDEFTETTSSAIVEVGGATRGKAIIILNPAEPPLIMRDTVFALVTAADPDVHEQIRASVDKMVADVAAYVPG
YRLKQAVQVTEIPADQPVHTLLAPDAERPTHQVSVFLEVEGAAHYLPAYAGNLDIMTSAALQVAERIAAGKADR

Sequences:

>Translated_314_residues
MTRTKVAIIGSGNIGTDLMIKVLRTSKHLEMGAMVGIDPASDGLARAGRFGVPTTAEGVEGLVALPGFDDIEIVFDATSA
GAHVVNAARLLPLGKRLIDLTPAALGPFTIPAVNLEDHLEAPNLNMVTCGGQATIPIVAAISRVVPVEYAEIVASIASRS
AGPGTRANIDEFTETTSSAIVEVGGATRGKAIIILNPAEPPLIMRDTVFALVTAADPDVHEQIRASVDKMVADVAAYVPG
YRLKQAVQVTEIPADQPVHTLLAPDAERPTHQVSVFLEVEGAAHYLPAYAGNLDIMTSAALQVAERIAAGKADR
>Mature_313_residues
TRTKVAIIGSGNIGTDLMIKVLRTSKHLEMGAMVGIDPASDGLARAGRFGVPTTAEGVEGLVALPGFDDIEIVFDATSAG
AHVVNAARLLPLGKRLIDLTPAALGPFTIPAVNLEDHLEAPNLNMVTCGGQATIPIVAAISRVVPVEYAEIVASIASRSA
GPGTRANIDEFTETTSSAIVEVGGATRGKAIIILNPAEPPLIMRDTVFALVTAADPDVHEQIRASVDKMVADVAAYVPGY
RLKQAVQVTEIPADQPVHTLLAPDAERPTHQVSVFLEVEGAAHYLPAYAGNLDIMTSAALQVAERIAAGKADR

Specific function: Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta- cleavage pathway for the degradation of aromatic compounds

COG id: COG4569

COG function: function code Q; Acetaldehyde dehydrogenase (acetylating)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetaldehyde dehydrogenase family

Homologues:

Organism=Escherichia coli, GI1786547, Length=316, Percent_Identity=65.5063291139241, Blast_Score=392, Evalue=1e-110,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACDH1_NOCSJ (A1SH78)

Other databases:

- EMBL:   CP000509
- RefSeq:   YP_922850.1
- ProteinModelPortal:   A1SH78
- SMR:   A1SH78
- STRING:   A1SH78
- GeneID:   4600029
- GenomeReviews:   CP000509_GR
- KEGG:   nca:Noca_1650
- eggNOG:   COG4569
- HOGENOM:   HBG300125
- OMA:   HVKNDAF
- ProtClustDB:   PRK08300
- BioCyc:   NSP35761:NOCA_1650-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01657
- InterPro:   IPR003361
- InterPro:   IPR015426
- InterPro:   IPR016040
- InterPro:   IPR000534
- Gene3D:   G3DSA:3.40.50.720
- PANTHER:   PTHR21123
- PIRSF:   PIRSF015689
- SMART:   SM00859
- TIGRFAMs:   TIGR03215

Pfam domain/function: PF09290 AcetDehyd-dimer; PF01118 Semialdhyde_dh

EC number: =1.2.1.10

Molecular weight: Translated: 32729; Mature: 32598

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: NA

Important sites: BINDING 292-292

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRTKVAIIGSGNIGTDLMIKVLRTSKHLEMGAMVGIDPASDGLARAGRFGVPTTAEGVE
CCCEEEEEEECCCCCHHHHHHHHHHCCCCCCCEEEECCCCCCHHHHCCCCCCCCCCCCCC
GLVALPGFDDIEIVFDATSAGAHVVNAARLLPLGKRLIDLTPAALGPFTIPAVNLEDHLE
CEEECCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCHHHHCC
APNLNMVTCGGQATIPIVAAISRVVPVEYAEIVASIASRSAGPGTRANIDEFTETTSSAI
CCCCEEEEECCCCHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHE
VEVGGATRGKAIIILNPAEPPLIMRDTVFALVTAADPDVHEQIRASVDKMVADVAAYVPG
EEECCCCCCCEEEEECCCCCCEEECCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCC
YRLKQAVQVTEIPADQPVHTLLAPDAERPTHQVSVFLEVEGAAHYLPAYAGNLDIMTSAA
HHHHHHHHHCCCCCCCCCHHHCCCCCCCCCEEEEEEEEECCCCCCCCHHCCCCHHHHHHH
LQVAERIAAGKADR
HHHHHHHHCCCCCC
>Mature Secondary Structure 
TRTKVAIIGSGNIGTDLMIKVLRTSKHLEMGAMVGIDPASDGLARAGRFGVPTTAEGVE
CCEEEEEEECCCCCHHHHHHHHHHCCCCCCCEEEECCCCCCHHHHCCCCCCCCCCCCCC
GLVALPGFDDIEIVFDATSAGAHVVNAARLLPLGKRLIDLTPAALGPFTIPAVNLEDHLE
CEEECCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCHHHHCC
APNLNMVTCGGQATIPIVAAISRVVPVEYAEIVASIASRSAGPGTRANIDEFTETTSSAI
CCCCEEEEECCCCHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHE
VEVGGATRGKAIIILNPAEPPLIMRDTVFALVTAADPDVHEQIRASVDKMVADVAAYVPG
EEECCCCCCCEEEEECCCCCCEEECCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCC
YRLKQAVQVTEIPADQPVHTLLAPDAERPTHQVSVFLEVEGAAHYLPAYAGNLDIMTSAA
HHHHHHHHHCCCCCCCCCHHHCCCCCCCCCEEEEEEEEECCCCCCCCHHCCCCHHHHHHH
LQVAERIAAGKADR
HHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA