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The map label for this gene is tcrA [H]

Identifier: 119715795

GI number: 119715795

Start: 1653232

End: 1653918

Strand: Direct

Name: tcrA [H]

Synonym: Noca_1559

Alternate gene names: 119715795

Gene position: 1653232-1653918 (Clockwise)

Preceding gene: 119715794

Following gene: 119715796

Centisome position: 33.16

GC content: 68.27

Gene sequence:

>687_bases
ATGAGGATTCTGGTGGCCGAGGACGATGTCCGCCTGGCCGGCCTGCTGGAGGAGTCACTGGCCGAGGCCGGGTGGCAGGT
CGAGGTGGTGCACAACGGCCGAGTCGCCTACGACCGGCTCCTGAGCGACACCAGCTTCGATGTGGCGCTCTTGGACTGGA
TGCTGCCCGGCATGGACGGCGTCACCGTTGCCCGCCGGCTGCGCGGCCTCGGGCTGGCGCTACCGATCCTGATGTTGACC
GCCCGAGGGGACGTGCGGGACCGCATCGACGGGCTCGACGCCGGTGCCGATGACTACCTCCCCAAGCCCTTCGACCTCGA
CGAGCTGCTGGCCCGCCTCCGGGCGCTGTACCGGCGTGGTGGCCTCGGCGGCGAGGCGCCGGTGCAGATCGGTGATCTGG
TCGTGGATCCAGGGGCTCGCAGGGTCTCCCGAGGCGGCGTCGAGATCATCTTGTCCACGCGTGAGTTCGACATCCTCTAT
CTGCTGGCCTCGCACGCCGGACAGGTGGTGACCCGGTTGACGATCCTCGACGAGGTCTGGGACGGCGAGACCGACCTGCG
CAGCAATGTCATCGACGTTCACCTCGCCGCCATCCGCGGCAAGATCGACAAGCCGTTTGGCACCGACACCATCACCACGC
TGCGGGGGGTCGGCTACCGGCTCGACATCCCAGCCGGGAAACGATGA

Upstream 100 bases:

>100_bases
CGCAGCAGTACCTGGTGCGGCACTACGTTGAGCAGGTGGCCTACGGCGACTGGCACATCTGGCGACGACTGGGCCAGCGC
GGCGGCATGGAGGCGGTGCG

Downstream 100 bases:

>100_bases
GCAGGCTCTGGGCACGCCTCTCCCGGTTGCCGCTGCGGGTCCGTCTGGTCGCCGGCTTCTCCGCCGCCAGCCTTGTGGTG
CTGATCGGTGCCGGGGTGTT

Product: response regulator receiver

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 228; Mature: 228

Protein sequence:

>228_residues
MRILVAEDDVRLAGLLEESLAEAGWQVEVVHNGRVAYDRLLSDTSFDVALLDWMLPGMDGVTVARRLRGLGLALPILMLT
ARGDVRDRIDGLDAGADDYLPKPFDLDELLARLRALYRRGGLGGEAPVQIGDLVVDPGARRVSRGGVEIILSTREFDILY
LLASHAGQVVTRLTILDEVWDGETDLRSNVIDVHLAAIRGKIDKPFGTDTITTLRGVGYRLDIPAGKR

Sequences:

>Translated_228_residues
MRILVAEDDVRLAGLLEESLAEAGWQVEVVHNGRVAYDRLLSDTSFDVALLDWMLPGMDGVTVARRLRGLGLALPILMLT
ARGDVRDRIDGLDAGADDYLPKPFDLDELLARLRALYRRGGLGGEAPVQIGDLVVDPGARRVSRGGVEIILSTREFDILY
LLASHAGQVVTRLTILDEVWDGETDLRSNVIDVHLAAIRGKIDKPFGTDTITTLRGVGYRLDIPAGKR
>Mature_228_residues
MRILVAEDDVRLAGLLEESLAEAGWQVEVVHNGRVAYDRLLSDTSFDVALLDWMLPGMDGVTVARRLRGLGLALPILMLT
ARGDVRDRIDGLDAGADDYLPKPFDLDELLARLRALYRRGGLGGEAPVQIGDLVVDPGARRVSRGGVEIILSTREFDILY
LLASHAGQVVTRLTILDEVWDGETDLRSNVIDVHLAAIRGKIDKPFGTDTITTLRGVGYRLDIPAGKR

Specific function: Member of the three-protein two-component system HK1/HK2/tcrA [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786784, Length=228, Percent_Identity=42.5438596491228, Blast_Score=176, Evalue=8e-46,
Organism=Escherichia coli, GI87082012, Length=221, Percent_Identity=40.2714932126697, Blast_Score=157, Evalue=4e-40,
Organism=Escherichia coli, GI1789809, Length=235, Percent_Identity=39.5744680851064, Blast_Score=149, Evalue=2e-37,
Organism=Escherichia coli, GI1789402, Length=221, Percent_Identity=38.0090497737557, Blast_Score=142, Evalue=2e-35,
Organism=Escherichia coli, GI1790552, Length=222, Percent_Identity=38.7387387387387, Blast_Score=139, Evalue=1e-34,
Organism=Escherichia coli, GI1786599, Length=225, Percent_Identity=34.2222222222222, Blast_Score=132, Evalue=1e-32,
Organism=Escherichia coli, GI1787375, Length=223, Percent_Identity=34.5291479820628, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI2367329, Length=227, Percent_Identity=38.3259911894273, Blast_Score=128, Evalue=3e-31,
Organism=Escherichia coli, GI1790860, Length=223, Percent_Identity=34.9775784753363, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI1786911, Length=179, Percent_Identity=38.5474860335196, Blast_Score=111, Evalue=3e-26,
Organism=Escherichia coli, GI1788394, Length=232, Percent_Identity=33.1896551724138, Blast_Score=111, Evalue=4e-26,
Organism=Escherichia coli, GI145693140, Length=230, Percent_Identity=31.7391304347826, Blast_Score=88, Evalue=5e-19,
Organism=Escherichia coli, GI1787229, Length=229, Percent_Identity=29.2576419213974, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1790863, Length=230, Percent_Identity=27.3913043478261, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1788550, Length=108, Percent_Identity=36.1111111111111, Blast_Score=78, Evalue=4e-16,
Organism=Escherichia coli, GI1790437, Length=126, Percent_Identity=34.1269841269841, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1790299, Length=109, Percent_Identity=37.6146788990826, Blast_Score=74, Evalue=8e-15,
Organism=Escherichia coli, GI145693157, Length=107, Percent_Identity=35.5140186915888, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 24949; Mature: 24949

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRILVAEDDVRLAGLLEESLAEAGWQVEVVHNGRVAYDRLLSDTSFDVALLDWMLPGMDG
CEEEEECCCCHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHCCCCCHHHHHHHHCCCCCH
VTVARRLRGLGLALPILMLTARGDVRDRIDGLDAGADDYLPKPFDLDELLARLRALYRRG
HHHHHHHHHCCHHHHHHHHHCCCCHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHC
GLGGEAPVQIGDLVVDPGARRVSRGGVEIILSTREFDILYLLASHAGQVVTRLTILDEVW
CCCCCCCEEECCEEECCCCHHHHCCCEEEEEECCCCCHHHEEHHHHHHHHHHHHHHHHHC
DGETDLRSNVIDVHLAAIRGKIDKPFGTDTITTLRGVGYRLDIPAGKR
CCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHCCCEEEECCCCCC
>Mature Secondary Structure
MRILVAEDDVRLAGLLEESLAEAGWQVEVVHNGRVAYDRLLSDTSFDVALLDWMLPGMDG
CEEEEECCCCHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHCCCCCHHHHHHHHCCCCCH
VTVARRLRGLGLALPILMLTARGDVRDRIDGLDAGADDYLPKPFDLDELLARLRALYRRG
HHHHHHHHHCCHHHHHHHHHCCCCHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHC
GLGGEAPVQIGDLVVDPGARRVSRGGVEIILSTREFDILYLLASHAGQVVTRLTILDEVW
CCCCCCCEEECCEEECCCCHHHHCCCEEEEEECCCCCHHHEEHHHHHHHHHHHHHHHHHC
DGETDLRSNVIDVHLAAIRGKIDKPFGTDTITTLRGVGYRLDIPAGKR
CCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHCCCEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230 [H]