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The map label for this gene is moeZ [H]

Identifier: 119715710

GI number: 119715710

Start: 1560721

End: 1561932

Strand: Direct

Name: moeZ [H]

Synonym: Noca_1474

Alternate gene names: 119715710

Gene position: 1560721-1561932 (Clockwise)

Preceding gene: 119715706

Following gene: 119715711

Centisome position: 31.3

GC content: 67.9

Gene sequence:

>1212_bases
GTGTCCTACCCCGCGCTCGTGGAGCCCGCGGACGAGCTGAGCATCGACGAGGTACGTCGTTACAGCCGCCACCTGATCAT
CCCCGACGTCGGGATGACCGGCCAGAAGCGGCTCAAGAACGCCAAGGTGCTGGTCATCGGCGCCGGCGGCCTCGGCAGCC
CGGCGCTCCTGTACCTGGCCGCGGCCGGCGTGGGCACGATCGGCATCGCGGAGTTCGACGAGGTCGACGAGTCGAACCTG
CAGCGCCAGGTCATCCACGGCGTGTCCGACATCGGGAAGTCCAAGGCCCTCTCGGCCAAGGAGTCGATCGCCGAGATCAA
CCCGTACGTCGACGTGGTGCTCCACGAGCAGCGCCTCGACAACGACAACGTGATGGGCGTCTTCGAGGGCTACGACCTGA
TCCTCGACGGCACCGACAACTTCGCGACCCGCTACATGGTCAACGACGCGGCGTACTTCCTCGGCATCCCCTACGTGTGG
GGCTCGATCTACCGCTTCGACGGCCAGGCGTCCGTGTTCGCCCCGTCCCTCGCCGACGACGCCCCCTGCTACCGCTGCCT
CTACCCGGAGCCGCCGCCGCCGGGCATGGTCCCCAGCTGCGCCGAGGGCGGCGTGCTCGGCGTGCTGTGCGCGGCGATCG
GCTCGATCCAGGTCAACGAGGGGATCAAGCTGCTCACCGGCATCGGTGACCCGCTGGTCGGCCGGCTGATGATCTACGAC
GCCCTCGAGATGGAGTACCGCAAGCTCAAGGTTCGCAAGGACCCCAACTGCGCACTGTGCGGTGACAACCCGACCGTCAC
CGGGCTGATCGACTACGAGACGTTCTGCGGTGCGGTCTCCGAGGCCGCGGCCGATGCAGCGGCCGGCTCGACCATCTCGG
TCACCCAGCTCGAGCACATGCTCAAGGAGCGCGAGGAGGGCACCCGCGACTTCGTCCTCGTCGACGTGCGCGAGCCGAAC
GAGTACGAGATCAACCGGATCCCCGGCTCGGTGCTGATCCCCAAGGGCGAGTTCCTCAACGGCAGCGCCCTCGAGCAGCT
GACCTCGCTCACCGGCGGAGACAAGCAGATCGTCATGCACTGCAAGTCCGGTGTCCGCTCCGCGGAGACGCTGGCCATCG
TCAAGGGCGCCGGCTATGCCGACGCCGTGCACGTCGGTGGCGGCGTGGTCGCCTGGGTCAACCAGATCGACCCCTCCCAG
CCCTCCTACTGA

Upstream 100 bases:

>100_bases
CGCGGCCGTCGGCTGCTTGGTCCGGCGGGGGAACATGGCAGAGCCGGACGGTGTTGTGTCCAGCGTCGCCAGGCGAATCG
ACCAAGCCAAGGAGTACGCC

Downstream 100 bases:

>100_bases
ACCCGATCTCCTGCGCCGAGTCGGCGCAACCTGCCCGCCTGAACGCGCCGAGTCGGCGCGTCATGCCCACCTGAGCGGGC
ACGATGCGCCGACTGGGCGG

Product: UBA/THIF-type NAD/FAD binding protein

Products: NA

Alternate protein names: Sulfur carrier protein CysO adenylyltransferase; Sulfur carrier protein CysO sulfurtransferase [H]

Number of amino acids: Translated: 403; Mature: 402

Protein sequence:

>403_residues
MSYPALVEPADELSIDEVRRYSRHLIIPDVGMTGQKRLKNAKVLVIGAGGLGSPALLYLAAAGVGTIGIAEFDEVDESNL
QRQVIHGVSDIGKSKALSAKESIAEINPYVDVVLHEQRLDNDNVMGVFEGYDLILDGTDNFATRYMVNDAAYFLGIPYVW
GSIYRFDGQASVFAPSLADDAPCYRCLYPEPPPPGMVPSCAEGGVLGVLCAAIGSIQVNEGIKLLTGIGDPLVGRLMIYD
ALEMEYRKLKVRKDPNCALCGDNPTVTGLIDYETFCGAVSEAAADAAAGSTISVTQLEHMLKEREEGTRDFVLVDVREPN
EYEINRIPGSVLIPKGEFLNGSALEQLTSLTGGDKQIVMHCKSGVRSAETLAIVKGAGYADAVHVGGGVVAWVNQIDPSQ
PSY

Sequences:

>Translated_403_residues
MSYPALVEPADELSIDEVRRYSRHLIIPDVGMTGQKRLKNAKVLVIGAGGLGSPALLYLAAAGVGTIGIAEFDEVDESNL
QRQVIHGVSDIGKSKALSAKESIAEINPYVDVVLHEQRLDNDNVMGVFEGYDLILDGTDNFATRYMVNDAAYFLGIPYVW
GSIYRFDGQASVFAPSLADDAPCYRCLYPEPPPPGMVPSCAEGGVLGVLCAAIGSIQVNEGIKLLTGIGDPLVGRLMIYD
ALEMEYRKLKVRKDPNCALCGDNPTVTGLIDYETFCGAVSEAAADAAAGSTISVTQLEHMLKEREEGTRDFVLVDVREPN
EYEINRIPGSVLIPKGEFLNGSALEQLTSLTGGDKQIVMHCKSGVRSAETLAIVKGAGYADAVHVGGGVVAWVNQIDPSQ
PSY
>Mature_402_residues
SYPALVEPADELSIDEVRRYSRHLIIPDVGMTGQKRLKNAKVLVIGAGGLGSPALLYLAAAGVGTIGIAEFDEVDESNLQ
RQVIHGVSDIGKSKALSAKESIAEINPYVDVVLHEQRLDNDNVMGVFEGYDLILDGTDNFATRYMVNDAAYFLGIPYVWG
SIYRFDGQASVFAPSLADDAPCYRCLYPEPPPPGMVPSCAEGGVLGVLCAAIGSIQVNEGIKLLTGIGDPLVGRLMIYDA
LEMEYRKLKVRKDPNCALCGDNPTVTGLIDYETFCGAVSEAAADAAAGSTISVTQLEHMLKEREEGTRDFVLVDVREPNE
YEINRIPGSVLIPKGEFLNGSALEQLTSLTGGDKQIVMHCKSGVRSAETLAIVKGAGYADAVHVGGGVVAWVNQIDPSQP
SY

Specific function: Catalyzes the conversion of the sulfur carrier protein CysO to CysO-thiocarboxylate. The reaction is thought to proceed in two steps:first, ATP-dependent activation of CysO as acyl- adenylate (CysO-COOAMP), followed by sulfur transfer to give CysO- thioca

COG id: COG0476

COG function: function code H; Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 rhodanese domain [H]

Homologues:

Organism=Homo sapiens, GI7657339, Length=417, Percent_Identity=37.410071942446, Blast_Score=247, Evalue=2e-65,
Organism=Homo sapiens, GI4885649, Length=151, Percent_Identity=31.1258278145695, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI38045942, Length=179, Percent_Identity=31.2849162011173, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI38045944, Length=179, Percent_Identity=31.2849162011173, Blast_Score=74, Evalue=2e-13,
Organism=Escherichia coli, GI1787048, Length=250, Percent_Identity=38.8, Blast_Score=195, Evalue=5e-51,
Organism=Escherichia coli, GI87082356, Length=242, Percent_Identity=38.4297520661157, Blast_Score=171, Evalue=6e-44,
Organism=Caenorhabditis elegans, GI17540406, Length=402, Percent_Identity=38.5572139303483, Blast_Score=272, Evalue=2e-73,
Organism=Caenorhabditis elegans, GI193203301, Length=168, Percent_Identity=28.5714285714286, Blast_Score=82, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI71984476, Length=177, Percent_Identity=32.7683615819209, Blast_Score=77, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6321903, Length=407, Percent_Identity=38.5749385749386, Blast_Score=261, Evalue=1e-70,
Organism=Saccharomyces cerevisiae, GI6320598, Length=177, Percent_Identity=29.3785310734463, Blast_Score=85, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6322639, Length=208, Percent_Identity=26.9230769230769, Blast_Score=70, Evalue=7e-13,
Organism=Saccharomyces cerevisiae, GI6325438, Length=153, Percent_Identity=30.718954248366, Blast_Score=70, Evalue=8e-13,
Organism=Drosophila melanogaster, GI24582879, Length=399, Percent_Identity=39.5989974937343, Blast_Score=302, Evalue=3e-82,
Organism=Drosophila melanogaster, GI24660640, Length=155, Percent_Identity=34.1935483870968, Blast_Score=89, Evalue=7e-18,
Organism=Drosophila melanogaster, GI28573937, Length=190, Percent_Identity=26.3157894736842, Blast_Score=69, Evalue=7e-12,
Organism=Drosophila melanogaster, GI20129973, Length=174, Percent_Identity=28.735632183908, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007901
- InterPro:   IPR009036
- InterPro:   IPR016040
- InterPro:   IPR001763
- InterPro:   IPR000594 [H]

Pfam domain/function: PF05237 MoeZ_MoeB; PF00581 Rhodanese; PF00899 ThiF [H]

EC number: NA

Molecular weight: Translated: 43132; Mature: 43000

Theoretical pI: Translated: 4.38; Mature: 4.38

Prosite motif: PS50206 RHODANESE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYPALVEPADELSIDEVRRYSRHLIIPDVGMTGQKRLKNAKVLVIGAGGLGSPALLYLA
CCCCCCCCCHHHCCHHHHHHHHCEEEECCCCCCCHHHHCCCEEEEEECCCCCCHHHHHHH
AAGVGTIGIAEFDEVDESNLQRQVIHGVSDIGKSKALSAKESIAEINPYVDVVLHEQRLD
HCCCCEEECCCHHHCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCEEEEEEHHHCC
NDNVMGVFEGYDLILDGTDNFATRYMVNDAAYFLGIPYVWGSIYRFDGQASVFAPSLADD
CCCEEEEECCCEEEEECCCCCEEEEEECCCHHEEECHHHHCCEEEECCCCEEECCCCCCC
APCYRCLYPEPPPPGMVPSCAEGGVLGVLCAAIGSIQVNEGIKLLTGIGDPLVGRLMIYD
CCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHCCEEECCCEEEEECCCCHHHHHHHHHH
ALEMEYRKLKVRKDPNCALCGDNPTVTGLIDYETFCGAVSEAAADAAAGSTISVTQLEHM
HHHHHHHHEEECCCCCEEEECCCCCEEEEEEHHHHHHHHHHHHHHHHCCCEEEHHHHHHH
LKEREEGTRDFVLVDVREPNEYEINRIPGSVLIPKGEFLNGSALEQLTSLTGGDKQIVMH
HHHHHCCCCCEEEEEECCCCCEEEEECCCEEEECCCCCCCCHHHHHHHHHCCCCCEEEEE
CKSGVRSAETLAIVKGAGYADAVHVGGGVVAWVNQIDPSQPSY
EHHCCCCCCEEEEEECCCCCCEEECCCCEEEEEECCCCCCCCC
>Mature Secondary Structure 
SYPALVEPADELSIDEVRRYSRHLIIPDVGMTGQKRLKNAKVLVIGAGGLGSPALLYLA
CCCCCCCCHHHCCHHHHHHHHCEEEECCCCCCCHHHHCCCEEEEEECCCCCCHHHHHHH
AAGVGTIGIAEFDEVDESNLQRQVIHGVSDIGKSKALSAKESIAEINPYVDVVLHEQRLD
HCCCCEEECCCHHHCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCEEEEEEHHHCC
NDNVMGVFEGYDLILDGTDNFATRYMVNDAAYFLGIPYVWGSIYRFDGQASVFAPSLADD
CCCEEEEECCCEEEEECCCCCEEEEEECCCHHEEECHHHHCCEEEECCCCEEECCCCCCC
APCYRCLYPEPPPPGMVPSCAEGGVLGVLCAAIGSIQVNEGIKLLTGIGDPLVGRLMIYD
CCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHCCEEECCCEEEEECCCCHHHHHHHHHH
ALEMEYRKLKVRKDPNCALCGDNPTVTGLIDYETFCGAVSEAAADAAAGSTISVTQLEHM
HHHHHHHHEEECCCCCEEEECCCCCEEEEEEHHHHHHHHHHHHHHHHCCCEEEHHHHHHH
LKEREEGTRDFVLVDVREPNEYEINRIPGSVLIPKGEFLNGSALEQLTSLTGGDKQIVMH
HHHHHCCCCCEEEEEECCCCCEEEEECCCEEEECCCCCCCCHHHHHHHHHCCCCCEEEEE
CKSGVRSAETLAIVKGAGYADAVHVGGGVVAWVNQIDPSQPSY
EHHCCCCCCEEEEEECCCCCCEEECCCCEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]