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The map label for this gene is sigW [H]

Identifier: 119715446

GI number: 119715446

Start: 1283940

End: 1284632

Strand: Direct

Name: sigW [H]

Synonym: Noca_1210

Alternate gene names: 119715446

Gene position: 1283940-1284632 (Clockwise)

Preceding gene: 119715444

Following gene: 119715447

Centisome position: 25.75

GC content: 73.3

Gene sequence:

>693_bases
GTGAGGAAGGACAAGACCCTGTTCCCCCAGGCACGCAAGCGCCAGCAGCCCCTCCAGGAGGCACCCATGGACACGCCGGT
GACCCCCGCTGCGGGCGGTCCTGCCGACCGACCGGCCGAGGGCGTCCCGTCCTGGGAGGAGATCGTCGAGCAGCACTCCG
ACCGGGTGTTCCGGCTGGCCTACCGTCTGACCGGCAACCGCCACGACGCCGAGGACCTCACCCAGGAGGTCTTCGTCCGG
GTGTTCCGTTCGCTGTCCACCTACACCCCCGGCACCTTCGAGGGCTGGCTGCACCGCATCACCACGAACCTCTTCCTCGA
CCAGGCCCGGCGCAAGCAGCGGATCCGCTTCGACGCCCTCTCCGACGAGCGCGCCGACCGGCTCACCAGCTCCTCGCCGA
GCCCGGATGCGGCGTACGCCGACCGCACCTTCGACGACGACATCGAGCGTGCCCTCGCGACCCTGCCGCCGGACTTCCGC
GCCGCGGTCGTCCTCTGCGACGTCGAGGGGCTCGCCTACGAGGAGATCGCCGAGATCCTGGGCGCCAAGCTCGGCACCGT
CCGCTCCCGCATCCACCGCGGCCGCGCCATGCTGCGCTCCGCCCTCGCGCACCGGGCGCCGAGCGCCGGCCGGGTGCGGT
ACGCCGGTCCCGCGGCCGGGCCGCTGCTCTCGGGCTGGGGGTCCGCGACGTGA

Upstream 100 bases:

>100_bases
TGAGGTCGCACCGGCCTCGCGAGAGACCCGCACCACCCGCGCGAAGAGCAGGCGAAAGAGACACGATGCTCACAGGTTCC
TCTCAGCAGAGGTCTCTACG

Downstream 100 bases:

>100_bases
TCGGCCACCACCTGGGCTCGCGCACCAGCGCCCTGCTCGACGGTCAGCTCTCCACCGACGAGACCGAGCGGGCCTGGGCG
CACGTGCACGGCTGCCACGC

Product: RNA polymerase sigma factor SigE

Products: NA

Alternate protein names: Sigma-W factor [H]

Number of amino acids: Translated: 230; Mature: 230

Protein sequence:

>230_residues
MRKDKTLFPQARKRQQPLQEAPMDTPVTPAAGGPADRPAEGVPSWEEIVEQHSDRVFRLAYRLTGNRHDAEDLTQEVFVR
VFRSLSTYTPGTFEGWLHRITTNLFLDQARRKQRIRFDALSDERADRLTSSSPSPDAAYADRTFDDDIERALATLPPDFR
AAVVLCDVEGLAYEEIAEILGAKLGTVRSRIHRGRAMLRSALAHRAPSAGRVRYAGPAAGPLLSGWGSAT

Sequences:

>Translated_230_residues
MRKDKTLFPQARKRQQPLQEAPMDTPVTPAAGGPADRPAEGVPSWEEIVEQHSDRVFRLAYRLTGNRHDAEDLTQEVFVR
VFRSLSTYTPGTFEGWLHRITTNLFLDQARRKQRIRFDALSDERADRLTSSSPSPDAAYADRTFDDDIERALATLPPDFR
AAVVLCDVEGLAYEEIAEILGAKLGTVRSRIHRGRAMLRSALAHRAPSAGRVRYAGPAAGPLLSGWGSAT
>Mature_230_residues
MRKDKTLFPQARKRQQPLQEAPMDTPVTPAAGGPADRPAEGVPSWEEIVEQHSDRVFRLAYRLTGNRHDAEDLTQEVFVR
VFRSLSTYTPGTFEGWLHRITTNLFLDQARRKQRIRFDALSDERADRLTSSSPSPDAAYADRTFDDDIERALATLPPDFR
AAVVLCDVEGLAYEEIAEILGAKLGTVRSRIHRGRAMLRSALAHRAPSAGRVRYAGPAAGPLLSGWGSAT

Specific function: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Sigma-W controls genes involved in transport processes and detoxification [H]

COG id: COG1595

COG function: function code K; DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sigma-70 factor family. ECF subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788926, Length=134, Percent_Identity=32.8358208955224, Blast_Score=72, Evalue=3e-14,

Paralogues:

None

Copy number: <10 [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014284
- InterPro:   IPR014294
- InterPro:   IPR000838
- InterPro:   IPR007627
- InterPro:   IPR013249
- InterPro:   IPR013325
- InterPro:   IPR013324
- InterPro:   IPR011991 [H]

Pfam domain/function: PF04542 Sigma70_r2; PF08281 Sigma70_r4_2 [H]

EC number: NA

Molecular weight: Translated: 25567; Mature: 25567

Theoretical pI: Translated: 9.04; Mature: 9.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKDKTLFPQARKRQQPLQEAPMDTPVTPAAGGPADRPAEGVPSWEEIVEQHSDRVFRLA
CCCCCCCCHHHHHHHCCHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
YRLTGNRHDAEDLTQEVFVRVFRSLSTYTPGTFEGWLHRITTNLFLDQARRKQRIRFDAL
HHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SDERADRLTSSSPSPDAAYADRTFDDDIERALATLPPDFRAAVVLCDVEGLAYEEIAEIL
CHHHHHHHHCCCCCCCCHHCCCCCHHHHHHHHHHCCCCHHEEEEEECCCCCCHHHHHHHH
GAKLGTVRSRIHRGRAMLRSALAHRAPSAGRVRYAGPAAGPLLSGWGSAT
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCHHHCCCCCCC
>Mature Secondary Structure
MRKDKTLFPQARKRQQPLQEAPMDTPVTPAAGGPADRPAEGVPSWEEIVEQHSDRVFRLA
CCCCCCCCHHHHHHHCCHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
YRLTGNRHDAEDLTQEVFVRVFRSLSTYTPGTFEGWLHRITTNLFLDQARRKQRIRFDAL
HHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SDERADRLTSSSPSPDAAYADRTFDDDIERALATLPPDFRAAVVLCDVEGLAYEEIAEIL
CHHHHHHHHCCCCCCCCHHCCCCCHHHHHHHHHHCCCCHHEEEEEECCCCCCHHHHHHHH
GAKLGTVRSRIHRGRAMLRSALAHRAPSAGRVRYAGPAAGPLLSGWGSAT
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9274029; 9384377; 12207695 [H]