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The map label for this gene is ycgM [C]

Identifier: 119715422

GI number: 119715422

Start: 1260194

End: 1261036

Strand: Direct

Name: ycgM [C]

Synonym: Noca_1186

Alternate gene names: 119715422

Gene position: 1260194-1261036 (Clockwise)

Preceding gene: 119715421

Following gene: 119715423

Centisome position: 25.28

GC content: 69.75

Gene sequence:

>843_bases
GTGAGGTACGTGACCTACGAGTCTCCGGAAGGCCGCGGTCGCCGGGTCGGGTACCTCGACGGCGACGCCGTGGTCGATGC
CGGGTTCGACGGCGACATGGTCGCGTTCATCGAGGCCGGGGCACCGGTCGGGACCACCCGGGGTGTCGCGAACGCGGTGC
TGCGGGCACCCTTGCGGCCACGCACGCTGCGTGACTTCCTCGCCTTCGAGGGCCATCTACTCAACGTCTTCCCGGCCCTC
GGCAAGGCGATACCGGAGGAGTGGTACCGGCTTCCGGCCTACTACAAGGGACTACCGGACACCGTGATCGGACCGGAGGA
CGAGATCCCGTGGCCGGCGTACACCCAGCGGCTCGACCACGAGCTCGAGCTCGCCGCGGTCATCGGCCGTCCGGGGAAGG
ACATCACCGAGGACAACGCCCTCGACCACGTCTTCGGCTACACGATCTGGAACGACCTCTCCGCGCGTGACGTCCAGGCG
GGCGAGCTGCCGGTGGGGATGGGTCCGGGCAAGGCGAAGGACTGGGACGGCTCGAACGTCCTCGGCCCCTGCATCGTCAC
CGCCGACGAGGTCGACCCGCACGACATCGAGCTCGAGGTCCGCGTCAACGGCGAGCGTTGGGGCGGCGCCAACACCCGGG
ACATGCACCATACGTTCGAGTCGATGATCGTCTACGCATCCCAGGCGCTGATGCTCCGACCCGGCGAGGTGCTCGGCTCC
GGCACGGCCACCGGGGGCAGCGGCGTGGAGCTGGGTCGCTGGCTCGCCCCCGCCGACACGGTCGAGATGGAGGCCTCCGG
CATCGGAGTACTCCGCAACGTCGTCGGGCACCGACCGGCCTGA

Upstream 100 bases:

>100_bases
GGCCTACGACTCCACCGGCCTCTACATGCTGCAGTCGCGGCCCGTCACGACGCTCTAGCGACCACCTGATGTCCATGGGC
GGAGCCGGGGAGGCCGGCCA

Downstream 100 bases:

>100_bases
CCCGAGATCACCACACCCATCCATCGAAGGAAGTAGAGGGAACGCACATGGCATTCGTCGTAGCCGCCATCTGGAAGGCC
AAGGAGGGCGAGCAGAAGCG

Product: fumarylacetoacetate (FAA) hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 280; Mature: 280

Protein sequence:

>280_residues
MRYVTYESPEGRGRRVGYLDGDAVVDAGFDGDMVAFIEAGAPVGTTRGVANAVLRAPLRPRTLRDFLAFEGHLLNVFPAL
GKAIPEEWYRLPAYYKGLPDTVIGPEDEIPWPAYTQRLDHELELAAVIGRPGKDITEDNALDHVFGYTIWNDLSARDVQA
GELPVGMGPGKAKDWDGSNVLGPCIVTADEVDPHDIELEVRVNGERWGGANTRDMHHTFESMIVYASQALMLRPGEVLGS
GTATGGSGVELGRWLAPADTVEMEASGIGVLRNVVGHRPA

Sequences:

>Translated_280_residues
MRYVTYESPEGRGRRVGYLDGDAVVDAGFDGDMVAFIEAGAPVGTTRGVANAVLRAPLRPRTLRDFLAFEGHLLNVFPAL
GKAIPEEWYRLPAYYKGLPDTVIGPEDEIPWPAYTQRLDHELELAAVIGRPGKDITEDNALDHVFGYTIWNDLSARDVQA
GELPVGMGPGKAKDWDGSNVLGPCIVTADEVDPHDIELEVRVNGERWGGANTRDMHHTFESMIVYASQALMLRPGEVLGS
GTATGGSGVELGRWLAPADTVEMEASGIGVLRNVVGHRPA
>Mature_280_residues
MRYVTYESPEGRGRRVGYLDGDAVVDAGFDGDMVAFIEAGAPVGTTRGVANAVLRAPLRPRTLRDFLAFEGHLLNVFPAL
GKAIPEEWYRLPAYYKGLPDTVIGPEDEIPWPAYTQRLDHELELAAVIGRPGKDITEDNALDHVFGYTIWNDLSARDVQA
GELPVGMGPGKAKDWDGSNVLGPCIVTADEVDPHDIELEVRVNGERWGGANTRDMHHTFESMIVYASQALMLRPGEVLGS
GTATGGSGVELGRWLAPADTVEMEASGIGVLRNVVGHRPA

Specific function: Unknown

COG id: COG0179

COG function: function code Q; 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAH family [H]

Homologues:

Organism=Homo sapiens, GI156231349, Length=296, Percent_Identity=31.7567567567568, Blast_Score=117, Evalue=1e-26,
Organism=Homo sapiens, GI40786394, Length=296, Percent_Identity=31.0810810810811, Blast_Score=112, Evalue=4e-25,
Organism=Homo sapiens, GI13654274, Length=148, Percent_Identity=34.4594594594595, Blast_Score=85, Evalue=8e-17,
Organism=Homo sapiens, GI215422413, Length=148, Percent_Identity=34.4594594594595, Blast_Score=85, Evalue=9e-17,
Organism=Homo sapiens, GI66348062, Length=148, Percent_Identity=34.4594594594595, Blast_Score=85, Evalue=9e-17,
Organism=Homo sapiens, GI4557587, Length=255, Percent_Identity=29.0196078431373, Blast_Score=69, Evalue=6e-12,
Organism=Escherichia coli, GI1787428, Length=167, Percent_Identity=31.7365269461078, Blast_Score=75, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17557057, Length=173, Percent_Identity=30.635838150289, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI28572127, Length=201, Percent_Identity=30.8457711442786, Blast_Score=94, Evalue=7e-20,
Organism=Drosophila melanogaster, GI24663695, Length=195, Percent_Identity=29.7435897435897, Blast_Score=85, Evalue=4e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002529
- InterPro:   IPR011234 [H]

Pfam domain/function: PF01557 FAA_hydrolase [H]

EC number: NA

Molecular weight: Translated: 30288; Mature: 30288

Theoretical pI: Translated: 4.51; Mature: 4.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRYVTYESPEGRGRRVGYLDGDAVVDAGFDGDMVAFIEAGAPVGTTRGVANAVLRAPLRP
CCEEECCCCCCCCCEEEEECCCEEEECCCCCCEEEEEECCCCCCCHHHHHHHHHHCCCCC
RTLRDFLAFEGHLLNVFPALGKAIPEEWYRLPAYYKGLPDTVIGPEDEIPWPAYTQRLDH
HHHHHHHHHCCHHHHHHHHHHHHCCHHHHHCCHHHCCCCCCCCCCCCCCCCCHHHHHCCC
ELELAAVIGRPGKDITEDNALDHVFGYTIWNDLSARDVQAGELPVGMGPGKAKDWDGSNV
HHEEEEEECCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
LGPCIVTADEVDPHDIELEVRVNGERWGGANTRDMHHTFESMIVYASQALMLRPGEVLGS
CCCEEEEECCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHEEECCCHHHCC
GTATGGSGVELGRWLAPADTVEMEASGIGVLRNVVGHRPA
CCCCCCCCCCHHHEECCCCCEEECCCCHHHHHHHHCCCCC
>Mature Secondary Structure
MRYVTYESPEGRGRRVGYLDGDAVVDAGFDGDMVAFIEAGAPVGTTRGVANAVLRAPLRP
CCEEECCCCCCCCCEEEEECCCEEEECCCCCCEEEEEECCCCCCCHHHHHHHHHHCCCCC
RTLRDFLAFEGHLLNVFPALGKAIPEEWYRLPAYYKGLPDTVIGPEDEIPWPAYTQRLDH
HHHHHHHHHCCHHHHHHHHHHHHCCHHHHHCCHHHCCCCCCCCCCCCCCCCCHHHHHCCC
ELELAAVIGRPGKDITEDNALDHVFGYTIWNDLSARDVQAGELPVGMGPGKAKDWDGSNV
HHEEEEEECCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
LGPCIVTADEVDPHDIELEVRVNGERWGGANTRDMHHTFESMIVYASQALMLRPGEVLGS
CCCEEEEECCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHEEECCCHHHCC
GTATGGSGVELGRWLAPADTVEMEASGIGVLRNVVGHRPA
CCCCCCCCCCHHHEECCCCCEEECCCCHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]