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The map label for this gene is xylB [H]

Identifier: 119715412

GI number: 119715412

Start: 1249339

End: 1250460

Strand: Reverse

Name: xylB [H]

Synonym: Noca_1176

Alternate gene names: 119715412

Gene position: 1250460-1249339 (Counterclockwise)

Preceding gene: 119715413

Following gene: 119715411

Centisome position: 25.08

GC content: 72.28

Gene sequence:

>1122_bases
GTGACCACCACGGCCACGTGTGCCGTCGTCCGCGAGACGGGCGGCCCGTTCCGGCTCGAGCAGGTCGAGCTCTCGGGGCC
TCGGCCGGACGAGGTTCTCGTCGAGGTGGTGGCCTCCGGCTTGTGCCACACCGACCTGCTGGTGCGCGACTCCCGGCCGG
ATTCCCTTCCCGCGGTGCTCGGTCACGAGGGAGCAGGGATCGTGAGGGAGACGGGAAGCGCGGTCCGCGAAGTCGGGGCC
GGTGACAAGGTGGTGCTCAGCTTCCCGTCCTGCGGCCGGTGCCGTCGCTGCCGCACCGGCTGGTCGGCGTACTGCGACTC
CATCGCGCAGCTGAAGTTCGGCTGCTGCCGCGCCGACGGCTCGGTGGCCACGACCGACCTGGACCACCGTCCGGTCGGGG
ACCATTTCTTCGGTCAATCCTCCTTCGGGACATTCTGCGTCGCCAACGCGCGCAGCGTCGTGAGAGTCCCGGACGACACC
GACCTGCGCATCGCCGGGCCGTTGGCCTGCGGGGTGCAGACCGGTGTCGGCGCCGTGCTCGACGTGCTCCGAGTGACCCC
CGGGTCCTCGGTGGCGGTCTACGGGACCGGCTCCGTCGGCCTGTGCGCCGTCATGGCGGCGCGGCTGTGCGGCGCGACCA
CGATCGTGGCGGTGAACCGCCGCGCCTCCCGGCTCGAGCTGGCGGCCGAGCTCGGGGCCACCCACCTGGTGTCGCCCGAG
GCGGTCGATCCGGTCGAGGCGATCCGGGAGGCGACCGGGGGCCGGGGCGTCGACTTCGCGCTCGAGACGACGGGCGTCCC
GACCGTCCTGACCCAGGCGGTGCGGTCGTTGGACTCCCTCGGCACCTGCGCCTTCGTCGGCACGGCACCGCCCGGCGCCA
CCGGGGGCATCGTGATGCTCGAGGCGATGACCAGGGGCCTGACCGTGCGCGGCGTCCTGCAGGGCGACAGCACTCCGAGC
CAGATGATCCCCCGCATGCTCACGCTGCACCAACGCGGCCTGCTCCCGTTCGACCGGTTGATCACCCACTACTCGTTCGA
CGAGATCAACCGGGCCGCCTCCGACTGCGTCAGCGGTGACGTGGTCAAGCCGGTGCTCCTGATGAGCGGCGGCCCGGCGT
GA

Upstream 100 bases:

>100_bases
GCGCCGTCCTCTTCTTCTGCACCGATGCCTCGTCCTTCGTGACCGGACAGCTGCTCACGCTCGACGGCGGCCTGACGGCC
ACCCAGTGAGTGATCCGTCC

Downstream 100 bases:

>100_bases
CGGGCGCACTCGACAGACAACCAGGCGTGGAGCACAGATGAGCGATCAGGTGACCGGCCCGGCGGCCCCCTCCCCCGGCC
TGGCCGTCTCTCCGCTGCTG

Product: alcohol dehydrogenase

Products: NA

Alternate protein names: Benzyl alcohol dehydrogenase; BADH [H]

Number of amino acids: Translated: 373; Mature: 372

Protein sequence:

>373_residues
MTTTATCAVVRETGGPFRLEQVELSGPRPDEVLVEVVASGLCHTDLLVRDSRPDSLPAVLGHEGAGIVRETGSAVREVGA
GDKVVLSFPSCGRCRRCRTGWSAYCDSIAQLKFGCCRADGSVATTDLDHRPVGDHFFGQSSFGTFCVANARSVVRVPDDT
DLRIAGPLACGVQTGVGAVLDVLRVTPGSSVAVYGTGSVGLCAVMAARLCGATTIVAVNRRASRLELAAELGATHLVSPE
AVDPVEAIREATGGRGVDFALETTGVPTVLTQAVRSLDSLGTCAFVGTAPPGATGGIVMLEAMTRGLTVRGVLQGDSTPS
QMIPRMLTLHQRGLLPFDRLITHYSFDEINRAASDCVSGDVVKPVLLMSGGPA

Sequences:

>Translated_373_residues
MTTTATCAVVRETGGPFRLEQVELSGPRPDEVLVEVVASGLCHTDLLVRDSRPDSLPAVLGHEGAGIVRETGSAVREVGA
GDKVVLSFPSCGRCRRCRTGWSAYCDSIAQLKFGCCRADGSVATTDLDHRPVGDHFFGQSSFGTFCVANARSVVRVPDDT
DLRIAGPLACGVQTGVGAVLDVLRVTPGSSVAVYGTGSVGLCAVMAARLCGATTIVAVNRRASRLELAAELGATHLVSPE
AVDPVEAIREATGGRGVDFALETTGVPTVLTQAVRSLDSLGTCAFVGTAPPGATGGIVMLEAMTRGLTVRGVLQGDSTPS
QMIPRMLTLHQRGLLPFDRLITHYSFDEINRAASDCVSGDVVKPVLLMSGGPA
>Mature_372_residues
TTTATCAVVRETGGPFRLEQVELSGPRPDEVLVEVVASGLCHTDLLVRDSRPDSLPAVLGHEGAGIVRETGSAVREVGAG
DKVVLSFPSCGRCRRCRTGWSAYCDSIAQLKFGCCRADGSVATTDLDHRPVGDHFFGQSSFGTFCVANARSVVRVPDDTD
LRIAGPLACGVQTGVGAVLDVLRVTPGSSVAVYGTGSVGLCAVMAARLCGATTIVAVNRRASRLELAAELGATHLVSPEA
VDPVEAIREATGGRGVDFALETTGVPTVLTQAVRSLDSLGTCAFVGTAPPGATGGIVMLEAMTRGLTVRGVLQGDSTPSQ
MIPRMLTLHQRGLLPFDRLITHYSFDEINRAASDCVSGDVVKPVLLMSGGPA

Specific function: Oxidizes primary alcohols with an aromatic or cyclohex- 1-ene ring. It is highly specific for benzyl alcohol [H]

COG id: COG1062

COG function: function code C; Zn-dependent alcohol dehydrogenases, class III

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI71565152, Length=371, Percent_Identity=34.2318059299191, Blast_Score=198, Evalue=6e-51,
Organism=Homo sapiens, GI34577061, Length=368, Percent_Identity=35.3260869565217, Blast_Score=188, Evalue=7e-48,
Organism=Homo sapiens, GI4501929, Length=371, Percent_Identity=33.1536388140162, Blast_Score=186, Evalue=2e-47,
Organism=Homo sapiens, GI156523966, Length=367, Percent_Identity=33.7874659400545, Blast_Score=186, Evalue=2e-47,
Organism=Homo sapiens, GI4501939, Length=351, Percent_Identity=34.4729344729345, Blast_Score=181, Evalue=9e-46,
Organism=Homo sapiens, GI4501933, Length=368, Percent_Identity=33.9673913043478, Blast_Score=179, Evalue=4e-45,
Organism=Homo sapiens, GI71565154, Length=371, Percent_Identity=30.4582210242588, Blast_Score=163, Evalue=2e-40,
Organism=Homo sapiens, GI71743840, Length=364, Percent_Identity=29.6703296703297, Blast_Score=155, Evalue=7e-38,
Organism=Homo sapiens, GI262073058, Length=364, Percent_Identity=29.9450549450549, Blast_Score=155, Evalue=8e-38,
Organism=Escherichia coli, GI1786552, Length=365, Percent_Identity=30.6849315068493, Blast_Score=142, Evalue=4e-35,
Organism=Escherichia coli, GI1786825, Length=380, Percent_Identity=28.6842105263158, Blast_Score=108, Evalue=6e-25,
Organism=Escherichia coli, GI1788073, Length=371, Percent_Identity=26.1455525606469, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI1788075, Length=329, Percent_Identity=26.7477203647416, Blast_Score=91, Evalue=9e-20,
Organism=Escherichia coli, GI1790045, Length=347, Percent_Identity=25.0720461095101, Blast_Score=88, Evalue=9e-19,
Organism=Escherichia coli, GI87081918, Length=227, Percent_Identity=29.0748898678414, Blast_Score=88, Evalue=9e-19,
Organism=Escherichia coli, GI1788407, Length=378, Percent_Identity=25.9259259259259, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI87082125, Length=283, Percent_Identity=26.5017667844523, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1787863, Length=351, Percent_Identity=23.9316239316239, Blast_Score=68, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI25146526, Length=370, Percent_Identity=31.6216216216216, Blast_Score=163, Evalue=1e-40,
Organism=Caenorhabditis elegans, GI71997431, Length=372, Percent_Identity=31.4516129032258, Blast_Score=159, Evalue=3e-39,
Organism=Caenorhabditis elegans, GI17565904, Length=347, Percent_Identity=31.4121037463977, Blast_Score=141, Evalue=5e-34,
Organism=Caenorhabditis elegans, GI17562876, Length=367, Percent_Identity=26.7029972752044, Blast_Score=94, Evalue=8e-20,
Organism=Caenorhabditis elegans, GI17562584, Length=318, Percent_Identity=26.7295597484277, Blast_Score=90, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI71988145, Length=301, Percent_Identity=28.5714285714286, Blast_Score=82, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17562878, Length=367, Percent_Identity=26.7029972752044, Blast_Score=81, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI17562582, Length=295, Percent_Identity=26.4406779661017, Blast_Score=73, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6320033, Length=372, Percent_Identity=32.5268817204301, Blast_Score=164, Evalue=2e-41,
Organism=Saccharomyces cerevisiae, GI6323961, Length=339, Percent_Identity=25.9587020648968, Blast_Score=84, Evalue=4e-17,
Organism=Saccharomyces cerevisiae, GI6323729, Length=341, Percent_Identity=26.6862170087977, Blast_Score=83, Evalue=7e-17,
Organism=Saccharomyces cerevisiae, GI6323099, Length=364, Percent_Identity=26.3736263736264, Blast_Score=83, Evalue=8e-17,
Organism=Saccharomyces cerevisiae, GI6319621, Length=334, Percent_Identity=25.748502994012, Blast_Score=80, Evalue=5e-16,
Organism=Saccharomyces cerevisiae, GI6324486, Length=339, Percent_Identity=25.6637168141593, Blast_Score=80, Evalue=8e-16,
Organism=Saccharomyces cerevisiae, GI6319257, Length=356, Percent_Identity=25.561797752809, Blast_Score=79, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6322619, Length=388, Percent_Identity=25, Blast_Score=76, Evalue=9e-15,
Organism=Saccharomyces cerevisiae, GI6319955, Length=388, Percent_Identity=25, Blast_Score=75, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6319258, Length=293, Percent_Identity=24.5733788395904, Blast_Score=70, Evalue=4e-13,
Organism=Drosophila melanogaster, GI17737895, Length=378, Percent_Identity=29.1005291005291, Blast_Score=152, Evalue=4e-37,
Organism=Drosophila melanogaster, GI17137530, Length=346, Percent_Identity=27.4566473988439, Blast_Score=78, Evalue=9e-15,
Organism=Drosophila melanogaster, GI17737897, Length=345, Percent_Identity=26.6666666666667, Blast_Score=75, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR002328
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.1.1.90 [H]

Molecular weight: Translated: 38705; Mature: 38573

Theoretical pI: Translated: 6.16; Mature: 6.16

Prosite motif: PS00059 ADH_ZINC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
3.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTTATCAVVRETGGPFRLEQVELSGPRPDEVLVEVVASGLCHTDLLVRDSRPDSLPAVL
CCCCEEEEEEECCCCCEEEEEEECCCCCHHHHHHHHHHHCCCHHHEEEECCCCCCCCHHH
GHEGAGIVRETGSAVREVGAGDKVVLSFPSCGRCRRCRTGWSAYCDSIAQLKFGCCRADG
CCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHCCCHHHHHHHHHHHHHHEEECCC
SVATTDLDHRPVGDHFFGQSSFGTFCVANARSVVRVPDDTDLRIAGPLACGVQTGVGAVL
CEEECCCCCCCCCCCCCCCCCCCCEEEECCCEEEECCCCCCEEEECCCHHCHHHHHHHHH
DVLRVTPGSSVAVYGTGSVGLCAVMAARLCGATTIVAVNRRASRLELAAELGATHLVSPE
HHHHCCCCCCEEEEECCCHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHCCCCCCCCC
AVDPVEAIREATGGRGVDFALETTGVPTVLTQAVRSLDSLGTCAFVGTAPPGATGGIVML
CCCHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHCCCEEEEECCCCCCCCCEEEE
EAMTRGLTVRGVLQGDSTPSQMIPRMLTLHQRGLLPFDRLITHYSFDEINRAASDCVSGD
EHHHCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCCHHHHHHHCCHHHHHHHHHHHCCCC
VVKPVLLMSGGPA
HHHHHHEECCCCC
>Mature Secondary Structure 
TTTATCAVVRETGGPFRLEQVELSGPRPDEVLVEVVASGLCHTDLLVRDSRPDSLPAVL
CCCEEEEEEECCCCCEEEEEEECCCCCHHHHHHHHHHHCCCHHHEEEECCCCCCCCHHH
GHEGAGIVRETGSAVREVGAGDKVVLSFPSCGRCRRCRTGWSAYCDSIAQLKFGCCRADG
CCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHCCCHHHHHHHHHHHHHHEEECCC
SVATTDLDHRPVGDHFFGQSSFGTFCVANARSVVRVPDDTDLRIAGPLACGVQTGVGAVL
CEEECCCCCCCCCCCCCCCCCCCCEEEECCCEEEECCCCCCEEEECCCHHCHHHHHHHHH
DVLRVTPGSSVAVYGTGSVGLCAVMAARLCGATTIVAVNRRASRLELAAELGATHLVSPE
HHHHCCCCCCEEEEECCCHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHCCCCCCCCC
AVDPVEAIREATGGRGVDFALETTGVPTVLTQAVRSLDSLGTCAFVGTAPPGATGGIVML
CCCHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHCCCEEEEECCCCCCCCCEEEE
EAMTRGLTVRGVLQGDSTPSQMIPRMLTLHQRGLLPFDRLITHYSFDEINRAASDCVSGD
EHHHCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCCHHHHHHHCCHHHHHHHHHHHCCCC
VVKPVLLMSGGPA
HHHHHHEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8496150; 1989592 [H]