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The map label for this gene is hcrA [H]

Identifier: 119715406

GI number: 119715406

Start: 1241056

End: 1243371

Strand: Direct

Name: hcrA [H]

Synonym: Noca_1169

Alternate gene names: 119715406

Gene position: 1241056-1243371 (Clockwise)

Preceding gene: 119715405

Following gene: 119715407

Centisome position: 24.89

GC content: 70.21

Gene sequence:

>2316_bases
ATGATCGAGCAGCAGGGCTCCGAACGGGAGGCACTGCGGACGGTGGGGGAGCCGATCCGACGCTACGGCGGTGCGGCCCG
GGTCGCCGGCCAGCAGGAGTTCCTGGCGGACCTCCACTTCCCCGACGCAGCCGCAGTGGCACTGGTCACCCTGCCGGTGG
CATGCGCGAGCGTCACCGGCGTCGACGGCAAGCGGGCCATGGAGATGCCCGGTGTGATCGCGGTGGTCAGCGCGGCCGAC
CTGCCGCAGCCGGTACCTCGCTTCGGCATCTCCCATCAGGATCGTCCGGTGCTCGCGGACGGGGAGGTCCTCTTCCACGG
CGAGCCGGTCGCGGCCGTGGTCGCGGAGACCCTCGACCAGGCCGAGGCCGGCGCGCGGGAGGTCGAGGTGACCTTCGAGG
AGAAGACGGGTGTCTACACCGTGGACGGGGCGTTGGCGGCCGGGGCCCCGCTCGTGAGGGACCCCTCCCTGCGCCCGGTG
GAGGACGAGAACCGCGACTCCAACGTCCTGGAGACCGCGTTGTACGAGTGGGGCGACACGGTGGCTGCCGCCGGCGAGGC
GGCGGTCATCGTGGAGAACACCTACACGTTCCCCATGGTGACCCACTTCCCGATCGAGCCGGGTGGCACCGTCGCGGTGC
CCACGGGCGCGGGCGGCCTCGACATCTACTCCCCGGTGCAGCACCCCTATCTGCTGCAACGCACCATTGCCACGGTCACC
GGTCTTCCGCTGTCCCAGGTCCGGGTCTTCGCCCCCGACCCGGGAGGTGGTTTCGGAGGCAAGCAGACCCCCAGGCTCGA
GCCGCTGCTGGCCTTCCTGGCGCTGCGGACCGGTCGAACCTGCCGGCTTGTGCTCTCGCTCGAGCAGACCTTCCAGATGA
TGCGCCGTGCGGCGTGCCGCGTGCAGGCACGCACGGGCTTCGCCGGCGACGGGGCGCTGATCTTCCACGAGCTGGAGTGT
GACTTCCTCATCGGGGCCTACGCCGACGTCGCTCCGCGGGTCATGACGAAGGGCAGCTACGTCGGCGCAGGTCCGTATCG
GATCCCCCGCGTCCGCACGGCCTCGCGCGCTGTCTTGTCGAACACCACGCCGAGCACCGCCTTCCGCGGCTTCGGCGCCC
CCCAGGTCGCGTGGGCGACCGAGTCGCAGCTGGATGCCGGTGCCCGGGCCCTGGGGTTGGACGGGCTCCAGATCCGCCGA
CGGAACCTCGTGAACATGGGTGAGGCGTTCTTCCGTGGCCCGTACGAGGCCACGGCGGACGGGCACTGGCACGAGGCGCT
GGAGAAAGCGGCCGAGCTGGTCGGGTGGGGTCAGCCGCTCGCGCCCGGTCGGGGCCGGGGCATCGCGGTCGCCATCAAGC
CCGGGGCGACCTCCGGTCTTTCCCAGAGCCTGGTGCGCTTCCTCGCGGACGGCAGCGCCATCGCCTACGCCGGCACCTCT
GACATGGGGCAGGGCGCTCGGACGCTCTGGCAGCAGATCCTCGCTGACGAGCTCGGCAGCCCGTTGGACAAGATCCGCGT
GGTGAGCGGGGACACCGGTGTCGTGCCCTTCGACCTGCAGACCTCGGCCAGCCGTTCCACGGTCTTCATGGGGAACGCGG
TCCTCGAGGCGTGCCGTGACATCAGGAAGCGAGTGCTGGCGCTCTACGCCGAGTCGACCGGGATCGACGAGGAGCTGCTG
TCCGAGGCCCCGGGCGTCCTGATCACCCCCGATGGCGAGCTCACCCTGCTCGAGGCGTCCCGCATCGCGCTGGGTGCTCT
CGGTGGCGAGTTCGTCGGACAGGGAACCGCTCGGATGCGAGGCCGCAAGGGACACCCGCTGGGTGGTGATGCCGCCTTCT
ACGAGTTCAACTGCACGGCGATCGAGGTGGAGGTCGACCTCGAGACCGGCGAGCTGCTGCTGCATCGGCACGTGTCGGTC
AGCGACGTCGGCACCGAGCTCAACCCCATCCAGGTCACCTCCCAGGACGAAGGCGCCTCGATCATGGGGCTCGGCCACAG
CCAGATGGAGCAGCTGCTCCTCGACGACCACGGAGTGATCCGCAACCTGGGAGCACTCGACTACCGGATCCCCACGTTCA
AGGACGTGCCCGTCGAGCTGATCACCCACGGGATCGAGAACCATGACGGACCTGGGCCGTACGGGTCGAAGGGGATCAGC
GAGGGCGCGTTGCTGTGCACAGCCGGCGCGCTGGGCTCAGCGGTCAGCGACGCGATCGGCACGCCGATCCGTGACCTGCC
GCTGACACCTGAGCGGGTCTGGACCGCGTTGCACCCTGATGTGACCGGCCGGCCAGGGGGTGAGGAGCACACCTAG

Upstream 100 bases:

>100_bases
AGGAGATTCGGGAAGGGATGTCGGGCAACCTGTGTCGCTGTGCGGGCTACCAGCGCATCGTCGCCGCAGTCGAACTGACC
TCGCGGAAGCGGGCGACCCG

Downstream 100 bases:

>100_bases
CAGCCGCGCGCCACGCAGCAGGCGAATCGACGACGTCGCCGCCGTGCGTGCCGCGCACGGACAGGGCCCGTGCCACCGCA
CCGGGGGCACCACACCGGAA

Product: xanthine dehydrogenase, molybdenum binding subunit apoprotein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 771; Mature: 771

Protein sequence:

>771_residues
MIEQQGSEREALRTVGEPIRRYGGAARVAGQQEFLADLHFPDAAAVALVTLPVACASVTGVDGKRAMEMPGVIAVVSAAD
LPQPVPRFGISHQDRPVLADGEVLFHGEPVAAVVAETLDQAEAGAREVEVTFEEKTGVYTVDGALAAGAPLVRDPSLRPV
EDENRDSNVLETALYEWGDTVAAAGEAAVIVENTYTFPMVTHFPIEPGGTVAVPTGAGGLDIYSPVQHPYLLQRTIATVT
GLPLSQVRVFAPDPGGGFGGKQTPRLEPLLAFLALRTGRTCRLVLSLEQTFQMMRRAACRVQARTGFAGDGALIFHELEC
DFLIGAYADVAPRVMTKGSYVGAGPYRIPRVRTASRAVLSNTTPSTAFRGFGAPQVAWATESQLDAGARALGLDGLQIRR
RNLVNMGEAFFRGPYEATADGHWHEALEKAAELVGWGQPLAPGRGRGIAVAIKPGATSGLSQSLVRFLADGSAIAYAGTS
DMGQGARTLWQQILADELGSPLDKIRVVSGDTGVVPFDLQTSASRSTVFMGNAVLEACRDIRKRVLALYAESTGIDEELL
SEAPGVLITPDGELTLLEASRIALGALGGEFVGQGTARMRGRKGHPLGGDAAFYEFNCTAIEVEVDLETGELLLHRHVSV
SDVGTELNPIQVTSQDEGASIMGLGHSQMEQLLLDDHGVIRNLGALDYRIPTFKDVPVELITHGIENHDGPGPYGSKGIS
EGALLCTAGALGSAVSDAIGTPIRDLPLTPERVWTALHPDVTGRPGGEEHT

Sequences:

>Translated_771_residues
MIEQQGSEREALRTVGEPIRRYGGAARVAGQQEFLADLHFPDAAAVALVTLPVACASVTGVDGKRAMEMPGVIAVVSAAD
LPQPVPRFGISHQDRPVLADGEVLFHGEPVAAVVAETLDQAEAGAREVEVTFEEKTGVYTVDGALAAGAPLVRDPSLRPV
EDENRDSNVLETALYEWGDTVAAAGEAAVIVENTYTFPMVTHFPIEPGGTVAVPTGAGGLDIYSPVQHPYLLQRTIATVT
GLPLSQVRVFAPDPGGGFGGKQTPRLEPLLAFLALRTGRTCRLVLSLEQTFQMMRRAACRVQARTGFAGDGALIFHELEC
DFLIGAYADVAPRVMTKGSYVGAGPYRIPRVRTASRAVLSNTTPSTAFRGFGAPQVAWATESQLDAGARALGLDGLQIRR
RNLVNMGEAFFRGPYEATADGHWHEALEKAAELVGWGQPLAPGRGRGIAVAIKPGATSGLSQSLVRFLADGSAIAYAGTS
DMGQGARTLWQQILADELGSPLDKIRVVSGDTGVVPFDLQTSASRSTVFMGNAVLEACRDIRKRVLALYAESTGIDEELL
SEAPGVLITPDGELTLLEASRIALGALGGEFVGQGTARMRGRKGHPLGGDAAFYEFNCTAIEVEVDLETGELLLHRHVSV
SDVGTELNPIQVTSQDEGASIMGLGHSQMEQLLLDDHGVIRNLGALDYRIPTFKDVPVELITHGIENHDGPGPYGSKGIS
EGALLCTAGALGSAVSDAIGTPIRDLPLTPERVWTALHPDVTGRPGGEEHT
>Mature_771_residues
MIEQQGSEREALRTVGEPIRRYGGAARVAGQQEFLADLHFPDAAAVALVTLPVACASVTGVDGKRAMEMPGVIAVVSAAD
LPQPVPRFGISHQDRPVLADGEVLFHGEPVAAVVAETLDQAEAGAREVEVTFEEKTGVYTVDGALAAGAPLVRDPSLRPV
EDENRDSNVLETALYEWGDTVAAAGEAAVIVENTYTFPMVTHFPIEPGGTVAVPTGAGGLDIYSPVQHPYLLQRTIATVT
GLPLSQVRVFAPDPGGGFGGKQTPRLEPLLAFLALRTGRTCRLVLSLEQTFQMMRRAACRVQARTGFAGDGALIFHELEC
DFLIGAYADVAPRVMTKGSYVGAGPYRIPRVRTASRAVLSNTTPSTAFRGFGAPQVAWATESQLDAGARALGLDGLQIRR
RNLVNMGEAFFRGPYEATADGHWHEALEKAAELVGWGQPLAPGRGRGIAVAIKPGATSGLSQSLVRFLADGSAIAYAGTS
DMGQGARTLWQQILADELGSPLDKIRVVSGDTGVVPFDLQTSASRSTVFMGNAVLEACRDIRKRVLALYAESTGIDEELL
SEAPGVLITPDGELTLLEASRIALGALGGEFVGQGTARMRGRKGHPLGGDAAFYEFNCTAIEVEVDLETGELLLHRHVSV
SDVGTELNPIQVTSQDEGASIMGLGHSQMEQLLLDDHGVIRNLGALDYRIPTFKDVPVELITHGIENHDGPGPYGSKGIS
EGALLCTAGALGSAVSDAIGTPIRDLPLTPERVWTALHPDVTGRPGGEEHT

Specific function: Catalyzes reductive dehydroxylation of 4-hydroxybenzoyl- CoA. Reaction is not reversible [H]

COG id: COG1529

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: To xanthine oxidases [H]

Homologues:

Organism=Homo sapiens, GI91823271, Length=778, Percent_Identity=26.6066838046273, Blast_Score=216, Evalue=4e-56,
Organism=Homo sapiens, GI71773480, Length=781, Percent_Identity=26.3764404609475, Blast_Score=198, Evalue=1e-50,
Organism=Escherichia coli, GI1789230, Length=773, Percent_Identity=28.7192755498059, Blast_Score=256, Evalue=5e-69,
Organism=Escherichia coli, GI1789246, Length=803, Percent_Identity=27.5217932752179, Blast_Score=243, Evalue=3e-65,
Organism=Escherichia coli, GI1786478, Length=771, Percent_Identity=27.367055771725, Blast_Score=155, Evalue=1e-38,
Organism=Caenorhabditis elegans, GI17540638, Length=788, Percent_Identity=25.761421319797, Blast_Score=187, Evalue=3e-47,
Organism=Caenorhabditis elegans, GI17539860, Length=763, Percent_Identity=23.8532110091743, Blast_Score=144, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI32566215, Length=756, Percent_Identity=23.2804232804233, Blast_Score=140, Evalue=3e-33,
Organism=Drosophila melanogaster, GI17737937, Length=787, Percent_Identity=26.6836086404066, Blast_Score=198, Evalue=1e-50,
Organism=Drosophila melanogaster, GI24647195, Length=762, Percent_Identity=24.6719160104987, Blast_Score=135, Evalue=2e-31,
Organism=Drosophila melanogaster, GI24647193, Length=777, Percent_Identity=24.7104247104247, Blast_Score=132, Evalue=1e-30,
Organism=Drosophila melanogaster, GI24647197, Length=758, Percent_Identity=24.802110817942, Blast_Score=129, Evalue=6e-30,
Organism=Drosophila melanogaster, GI24647199, Length=756, Percent_Identity=23.015873015873, Blast_Score=128, Evalue=2e-29,
Organism=Drosophila melanogaster, GI24647201, Length=771, Percent_Identity=23.4760051880674, Blast_Score=117, Evalue=2e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017607
- InterPro:   IPR000674
- InterPro:   IPR008274 [H]

Pfam domain/function: PF01315 Ald_Xan_dh_C; PF02738 Ald_Xan_dh_C2 [H]

EC number: =1.3.99.20 [H]

Molecular weight: Translated: 81452; Mature: 81452

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIEQQGSEREALRTVGEPIRRYGGAARVAGQQEFLADLHFPDAAAVALVTLPVACASVTG
CCCCCCCHHHHHHHHHHHHHHCCCCEEECCHHHHHHHCCCCCHHHHHHHHHHHHHHHCCC
VDGKRAMEMPGVIAVVSAADLPQPVPRFGISHQDRPVLADGEVLFHGEPVAAVVAETLDQ
CCCCHHHCCCCEEEEEECCCCCCCCHHCCCCCCCCCEEECCEEEECCCCHHHHHHHHHHH
AEAGAREVEVTFEEKTGVYTVDGALAAGAPLVRDPSLRPVEDENRDSNVLETALYEWGDT
HHCCCEEEEEEEECCCCEEEECCHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCH
VAAAGEAAVIVENTYTFPMVTHFPIEPGGTVAVPTGAGGLDIYSPVQHPYLLQRTIATVT
HHCCCCEEEEEECCCCCCEEEEECCCCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHHC
GLPLSQVRVFAPDPGGGFGGKQTPRLEPLLAFLALRTGRTCRLVLSLEQTFQMMRRAACR
CCCHHHEEEECCCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEEEEEHHHHHHHHHHHHHH
VQARTGFAGDGALIFHELECDFLIGAYADVAPRVMTKGSYVGAGPYRIPRVRTASRAVLS
EECCCCCCCCCEEEEEEECCCEEEECHHHHHHHHHCCCCEECCCCCCCCCCCHHHHHHHC
NTTPSTAFRGFGAPQVAWATESQLDAGARALGLDGLQIRRRNLVNMGEAFFRGPYEATAD
CCCCCHHHCCCCCCCEEECCCHHHCCCCHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCC
GHWHEALEKAAELVGWGQPLAPGRGRGIAVAIKPGATSGLSQSLVRFLADGSAIAYAGTS
CHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHCCCEEEEECCC
DMGQGARTLWQQILADELGSPLDKIRVVSGDTGVVPFDLQTSASRSTVFMGNAVLEACRD
CCCHHHHHHHHHHHHHHHCCCHHHEEEEECCCCEEEEECCCCCCCCEEEECHHHHHHHHH
IRKRVLALYAESTGIDEELLSEAPGVLITPDGELTLLEASRIALGALGGEFVGQGTARMR
HHHHHHHHHHHCCCCCHHHHHHCCCEEECCCCCEEEEECCHHHHCCCCCHHHCCCHHHHC
GRKGHPLGGDAAFYEFNCTAIEVEVDLETGELLLHRHVSVSDVGTELNPIQVTSQDEGAS
CCCCCCCCCCCEEEEEEEEEEEEEEECCCCCEEEEECCCHHHCCCCCCCEEEECCCCCCE
IMGLGHSQMEQLLLDDHGVIRNLGALDYRIPTFKDVPVELITHGIENHDGPGPYGSKGIS
EEECCHHHHHHHHHCCCHHHHHCCCCCEECCCCCCCCHHHHHHCCCCCCCCCCCCCCCCC
EGALLCTAGALGSAVSDAIGTPIRDLPLTPERVWTALHPDVTGRPGGEEHT
CCEEEEECCHHHHHHHHHHCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MIEQQGSEREALRTVGEPIRRYGGAARVAGQQEFLADLHFPDAAAVALVTLPVACASVTG
CCCCCCCHHHHHHHHHHHHHHCCCCEEECCHHHHHHHCCCCCHHHHHHHHHHHHHHHCCC
VDGKRAMEMPGVIAVVSAADLPQPVPRFGISHQDRPVLADGEVLFHGEPVAAVVAETLDQ
CCCCHHHCCCCEEEEEECCCCCCCCHHCCCCCCCCCEEECCEEEECCCCHHHHHHHHHHH
AEAGAREVEVTFEEKTGVYTVDGALAAGAPLVRDPSLRPVEDENRDSNVLETALYEWGDT
HHCCCEEEEEEEECCCCEEEECCHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCH
VAAAGEAAVIVENTYTFPMVTHFPIEPGGTVAVPTGAGGLDIYSPVQHPYLLQRTIATVT
HHCCCCEEEEEECCCCCCEEEEECCCCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHHC
GLPLSQVRVFAPDPGGGFGGKQTPRLEPLLAFLALRTGRTCRLVLSLEQTFQMMRRAACR
CCCHHHEEEECCCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEEEEEHHHHHHHHHHHHHH
VQARTGFAGDGALIFHELECDFLIGAYADVAPRVMTKGSYVGAGPYRIPRVRTASRAVLS
EECCCCCCCCCEEEEEEECCCEEEECHHHHHHHHHCCCCEECCCCCCCCCCCHHHHHHHC
NTTPSTAFRGFGAPQVAWATESQLDAGARALGLDGLQIRRRNLVNMGEAFFRGPYEATAD
CCCCCHHHCCCCCCCEEECCCHHHCCCCHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCC
GHWHEALEKAAELVGWGQPLAPGRGRGIAVAIKPGATSGLSQSLVRFLADGSAIAYAGTS
CHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHCCCEEEEECCC
DMGQGARTLWQQILADELGSPLDKIRVVSGDTGVVPFDLQTSASRSTVFMGNAVLEACRD
CCCHHHHHHHHHHHHHHHCCCHHHEEEEECCCCEEEEECCCCCCCCEEEECHHHHHHHHH
IRKRVLALYAESTGIDEELLSEAPGVLITPDGELTLLEASRIALGALGGEFVGQGTARMR
HHHHHHHHHHHCCCCCHHHHHHCCCEEECCCCCEEEEECCHHHHCCCCCHHHCCCHHHHC
GRKGHPLGGDAAFYEFNCTAIEVEVDLETGELLLHRHVSVSDVGTELNPIQVTSQDEGAS
CCCCCCCCCCCEEEEEEEEEEEEEEECCCCCEEEEECCCHHHCCCCCCCEEEECCCCCCE
IMGLGHSQMEQLLLDDHGVIRNLGALDYRIPTFKDVPVELITHGIENHDGPGPYGSKGIS
EEECCHHHHHHHHHCCCHHHHHCCCCCEECCCCCCCCHHHHHHCCCCCCCCCCCCCCCCC
EGALLCTAGALGSAVSDAIGTPIRDLPLTPERVWTALHPDVTGRPGGEEHT
CCEEEEECCHHHHHHHHHHCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9490068 [H]