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The map label for this gene is yedX [H]

Identifier: 119715381

GI number: 119715381

Start: 1214782

End: 1215111

Strand: Reverse

Name: yedX [H]

Synonym: Noca_1143

Alternate gene names: 119715381

Gene position: 1215111-1214782 (Counterclockwise)

Preceding gene: 119715382

Following gene: 119715380

Centisome position: 24.37

GC content: 71.82

Gene sequence:

>330_bases
ATGACGACGCTGTCCACCCACGTCCTCGACGCCGGGCGCGGGGTGCCGGCCGAGGGCCTCGACGTCCGCCTCGCCGGCCA
CCTCGTCGCCGGCGACGGCACCCTGGCCACCTCGCGGACCGACGCCGACGGCCGGGTGCGCTTCGACGTCGAGCTCCAGA
GCGGGCCGCACCTGCTGACGTTCGAGACCGGCGCCTGGTTCGACGCCCAGGGACGCGACACCTTCTTCTCCCTGGTCAAC
GTCGCCTTCGAGGTCGACGCCGAGGAGGAGCACCACCACGTGGCGCTGCTGCTGAGCCCGTACTCCTACACGACCTACAA
GGGGAGCTGA

Upstream 100 bases:

>100_bases
TCCTCGAGCAGCGGCTCGCGAACGACCCCGAGACCGAGCTGGCCGTCACCGCGGACCAGCTGCGCGAGATCGCGCTGCTG
CGACTGGAAGGACTGTTCTC

Downstream 100 bases:

>100_bases
GATGGCCACCACGGACGGGTCGAGGATCGTGCTCGGCGCCAACCAGTACGGCAAGGCCGAGGTGCGGCTGCTGCGGGTCG
ACCGGGCGAGCGAGCGGCAC

Product: transthyretin

Products: NA

Alternate protein names: HIU hydrolase; HIUHase; Transthyretin-like protein; TLP; Transthyretin-related protein; TRP [H]

Number of amino acids: Translated: 109; Mature: 108

Protein sequence:

>109_residues
MTTLSTHVLDAGRGVPAEGLDVRLAGHLVAGDGTLATSRTDADGRVRFDVELQSGPHLLTFETGAWFDAQGRDTFFSLVN
VAFEVDAEEEHHHVALLLSPYSYTTYKGS

Sequences:

>Translated_109_residues
MTTLSTHVLDAGRGVPAEGLDVRLAGHLVAGDGTLATSRTDADGRVRFDVELQSGPHLLTFETGAWFDAQGRDTFFSLVN
VAFEVDAEEEHHHVALLLSPYSYTTYKGS
>Mature_108_residues
TTLSTHVLDAGRGVPAEGLDVRLAGHLVAGDGTLATSRTDADGRVRFDVELQSGPHLLTFETGAWFDAQGRDTFFSLVNV
AFEVDAEEEHHHVALLLSPYSYTTYKGS

Specific function: Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU) [H]

COG id: COG2351

COG function: function code R; Transthyretin-like protein

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788281, Length=109, Percent_Identity=38.5321100917431, Blast_Score=78, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI115534555, Length=110, Percent_Identity=33.6363636363636, Blast_Score=68, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI115532920, Length=112, Percent_Identity=33.0357142857143, Blast_Score=65, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI115532922, Length=112, Percent_Identity=33.0357142857143, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014306
- InterPro:   IPR000895 [H]

Pfam domain/function: PF00576 Transthyretin [H]

EC number: =3.5.2.17 [H]

Molecular weight: Translated: 11791; Mature: 11660

Theoretical pI: Translated: 4.63; Mature: 4.63

Prosite motif: PS00768 TRANSTHYRETIN_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTLSTHVLDAGRGVPAEGLDVRLAGHLVAGDGTLATSRTDADGRVRFDVELQSGPHLLT
CCCCCCEEEECCCCCCCCCEEEEEEEEEEECCCEEEECCCCCCCEEEEEEEECCCCEEEE
FETGAWFDAQGRDTFFSLVNVAFEVDAEEEHHHVALLLSPYSYTTYKGS
EECCCEEECCCCHHHEEEEEEEEEECCCCCCCEEEEEECCCEEEEEECC
>Mature Secondary Structure 
TTLSTHVLDAGRGVPAEGLDVRLAGHLVAGDGTLATSRTDADGRVRFDVELQSGPHLLT
CCCCCEEEECCCCCCCCCEEEEEEEEEEECCCEEEECCCCCCCEEEEEEEECCCCEEEE
FETGAWFDAQGRDTFFSLVNVAFEVDAEEEHHHVALLLSPYSYTTYKGS
EECCCEEECCCCHHHEEEEEEEEEECCCCCCCEEEEEECCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9723926 [H]