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The map label for this gene is murB [H]

Identifier: 119714920

GI number: 119714920

Start: 711522

End: 712544

Strand: Direct

Name: murB [H]

Synonym: Noca_0672

Alternate gene names: 119714920

Gene position: 711522-712544 (Clockwise)

Preceding gene: 119714919

Following gene: 119714924

Centisome position: 14.27

GC content: 74.58

Gene sequence:

>1023_bases
GTGCCTGATCTCGCCGACCACACGACGCTGCGGCTCGGCGGTCCGGCCGGCCGCTGGGTGCGCGCCACCTCCGAGGACGA
GCTCGTCGCGGCGGTGAGCGAGGCCGACGGCGCCGGCGAGCCCGTGCTGGTGCTCGGCGGCGGGAGCAACCTCGTCGTGT
CCGACGACGGCTTCCCGGGCACCGTCGTCGAGGTCGCCACGCGCGGCGTCGTACCCGACGTCGAGGACGGCGCCTCCTGC
GGCGGGGTCCTGGTCACGGTCGCAGCCGGCGAGACGTGGGACGACCTGGTCGCACTCGCCGTCGAGCGGGAGTGGTCCGG
GATCGAGGCGCTGTCCGGCATTCCCGGATCCGTGGGCGCCACGCCGATCCAGAACGTCGGCGCCTACGGCCAGGAGGTCG
CCCAGACGATCGCCAGCGTCCGGGTCTGGGACCGGACGCTGCGCGGGGTCCGCACGTTCGCCGGCGCCGACTGCGGCTTC
GGCTACCGCACCTCCCGGTTCAAGCAGGACCCCGGGCGGCACGTCGTGCTGTCGGTGACGTTCCAGTTCCGCCAGGGCTC
GCTCGGAGCGCCGGTGAGCTACGCCGAGCTGGCCCGCGCCGTGGGTGTGGAGGTCGGTCAGCGGGCCCCGTCGGCGCAGG
TGCGCCGGGCGGTCCTCTCCCTGCGGTCCGGCAAGGGCATGGTCCTCGACCCGGCCGACCACGACACCTGGAGTGCCGGG
TCGTTCTTCACCAACCCGGTCGTCCCCGCGGACGCCGTACCGGACGGAGCGCCGGCGTGGCCCCAGCCCGACGGCCGGGT
GAAGACCAGCGCCGCCTGGCTGATCGAGCAGGCCGGCTTCGGCAAGGGGTACGGCGCGGGCCCGGCGAGGCTGTCCGGGA
AGCACACACTGGCGCTGACGAACCGCGGCAGCGCGACGACCGCGGACCTGCTGCAACTCGCGCGCGAGGTGCGCGACGGG
GTCGAGGCGCGGTTCGGGATCCGGCTGGTCAACGAGCCGGTGCTGGTCGGTTGTGAGCTCTGA

Upstream 100 bases:

>100_bases
GTCGCCGGGGAAGCCGAGGAGGCCGACGGCGTGACGACCGTGAAGCTGACGGTCACCTGCGCGGGCCAGAAGGTCCTGGG
CATGCCGAAGGCCGTCCTCC

Downstream 100 bases:

>100_bases
CCCGCGGGGAGGATCCCCGGCTACGGGCTCGTGGTCGCGACCCCGACGAAGAGGGCGATGAAGGCGAGCACGATCACGAC
CGCGAGGGCCAGCAGGCCGG

Product: UDP-N-acetylenolpyruvoylglucosamine reductase

Products: NA

Alternate protein names: UDP-N-acetylmuramate dehydrogenase [H]

Number of amino acids: Translated: 340; Mature: 339

Protein sequence:

>340_residues
MPDLADHTTLRLGGPAGRWVRATSEDELVAAVSEADGAGEPVLVLGGGSNLVVSDDGFPGTVVEVATRGVVPDVEDGASC
GGVLVTVAAGETWDDLVALAVEREWSGIEALSGIPGSVGATPIQNVGAYGQEVAQTIASVRVWDRTLRGVRTFAGADCGF
GYRTSRFKQDPGRHVVLSVTFQFRQGSLGAPVSYAELARAVGVEVGQRAPSAQVRRAVLSLRSGKGMVLDPADHDTWSAG
SFFTNPVVPADAVPDGAPAWPQPDGRVKTSAAWLIEQAGFGKGYGAGPARLSGKHTLALTNRGSATTADLLQLAREVRDG
VEARFGIRLVNEPVLVGCEL

Sequences:

>Translated_340_residues
MPDLADHTTLRLGGPAGRWVRATSEDELVAAVSEADGAGEPVLVLGGGSNLVVSDDGFPGTVVEVATRGVVPDVEDGASC
GGVLVTVAAGETWDDLVALAVEREWSGIEALSGIPGSVGATPIQNVGAYGQEVAQTIASVRVWDRTLRGVRTFAGADCGF
GYRTSRFKQDPGRHVVLSVTFQFRQGSLGAPVSYAELARAVGVEVGQRAPSAQVRRAVLSLRSGKGMVLDPADHDTWSAG
SFFTNPVVPADAVPDGAPAWPQPDGRVKTSAAWLIEQAGFGKGYGAGPARLSGKHTLALTNRGSATTADLLQLAREVRDG
VEARFGIRLVNEPVLVGCEL
>Mature_339_residues
PDLADHTTLRLGGPAGRWVRATSEDELVAAVSEADGAGEPVLVLGGGSNLVVSDDGFPGTVVEVATRGVVPDVEDGASCG
GVLVTVAAGETWDDLVALAVEREWSGIEALSGIPGSVGATPIQNVGAYGQEVAQTIASVRVWDRTLRGVRTFAGADCGFG
YRTSRFKQDPGRHVVLSVTFQFRQGSLGAPVSYAELARAVGVEVGQRAPSAQVRRAVLSLRSGKGMVLDPADHDTWSAGS
FFTNPVVPADAVPDGAPAWPQPDGRVKTSAAWLIEQAGFGKGYGAGPARLSGKHTLALTNRGSATTADLLQLAREVRDGV
EARFGIRLVNEPVLVGCEL

Specific function: Cell wall formation [H]

COG id: COG0812

COG function: function code M; UDP-N-acetylmuramate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

Organism=Escherichia coli, GI1790407, Length=338, Percent_Identity=34.6153846153846, Blast_Score=150, Evalue=1e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR003170
- InterPro:   IPR011601
- InterPro:   IPR006094 [H]

Pfam domain/function: PF01565 FAD_binding_4; PF02873 MurB_C [H]

EC number: =1.1.1.158 [H]

Molecular weight: Translated: 35263; Mature: 35132

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDLADHTTLRLGGPAGRWVRATSEDELVAAVSEADGAGEPVLVLGGGSNLVVSDDGFPG
CCCCCCCCEEEECCCCCCEEEECCCCCEEEEECCCCCCCCCEEEEECCCEEEEECCCCCC
TVVEVATRGVVPDVEDGASCGGVLVTVAAGETWDDLVALAVEREWSGIEALSGIPGSVGA
HHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHCCCCCHHHHCCCCCCCCC
TPIQNVGAYGQEVAQTIASVRVWDRTLRGVRTFAGADCGFGYRTSRFKQDPGRHVVLSVT
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEEE
FQFRQGSLGAPVSYAELARAVGVEVGQRAPSAQVRRAVLSLRSGKGMVLDPADHDTWSAG
EEECCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCEECCCCCCCCCCC
SFFTNPVVPADAVPDGAPAWPQPDGRVKTSAAWLIEQAGFGKGYGAGPARLSGKHTLALT
CCCCCCCCCCCCCCCCCCCCCCCCCCEEHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEE
NRGSATTADLLQLAREVRDGVEARFGIRLVNEPVLVGCEL
CCCCCCHHHHHHHHHHHHHHHHHEECEEEECCCEEEEECC
>Mature Secondary Structure 
PDLADHTTLRLGGPAGRWVRATSEDELVAAVSEADGAGEPVLVLGGGSNLVVSDDGFPG
CCCCCCCEEEECCCCCCEEEECCCCCEEEEECCCCCCCCCEEEEECCCEEEEECCCCCC
TVVEVATRGVVPDVEDGASCGGVLVTVAAGETWDDLVALAVEREWSGIEALSGIPGSVGA
HHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHCCCCCHHHHCCCCCCCCC
TPIQNVGAYGQEVAQTIASVRVWDRTLRGVRTFAGADCGFGYRTSRFKQDPGRHVVLSVT
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEEE
FQFRQGSLGAPVSYAELARAVGVEVGQRAPSAQVRRAVLSLRSGKGMVLDPADHDTWSAG
EEECCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCEECCCCCCCCCCC
SFFTNPVVPADAVPDGAPAWPQPDGRVKTSAAWLIEQAGFGKGYGAGPARLSGKHTLALT
CCCCCCCCCCCCCCCCCCCCCCCCCCEEHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEE
NRGSATTADLLQLAREVRDGVEARFGIRLVNEPVLVGCEL
CCCCCCHHHHHHHHHHHHHHHHHEECEEEECCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA