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The map label for this gene is gcvT [H]

Identifier: 119714890

GI number: 119714890

Start: 679574

End: 682021

Strand: Direct

Name: gcvT [H]

Synonym: Noca_0642

Alternate gene names: 119714890

Gene position: 679574-682021 (Clockwise)

Preceding gene: 119714884

Following gene: 119714891

Centisome position: 13.63

GC content: 63.28

Gene sequence:

>2448_bases
ATGGGAGAGCAGCAACAGCCGGCGCGCGCGCAGGTCGTCATCGTGGGTGGCGGCATCATTGGGACGAGCACTGCGTATCA
CCTGGCTTGCCGTGGTTGGACGGACGTTGTACTGCTTGAGCGCAACACCCTGACTTCGGGCACGACTTGGCACGCGGCAG
GGCTCGTGACCCAGGCGCGAGGGACATGGGGGACCCGCGAAGTCGTTCAGCGAAGTCTCGACGTGTTCCGCAACCTCGAA
CACGACACCGGCTTCTCTACCGGTTTCGTAAAGACCGGGACGATGAACCTCGCCACGTCCGCTGACCGGTTCGATGAGAT
GCGCCAGCTTGCAAGCGTCGTCCGCGGGAACGGTATCGATGCTGACCTTCTAGACGTCGACCGCACGCTCGAACTCCACC
CGCTCCTCAACAGCGATGGTCTCTACGGCAGCCTCTACTTCCCTGAGGACGGTCGCGGTAGCGCCACCGACACGACGATC
GCGCTGGCGCGCGGTGCGACTAGTCGCGGCGTGCGAATCATCGAGAACGTCGCTGTCGCCGGCGTCATGACAGCTGGCGA
CCGTGTTCGCGGAGTGCGTACGACAGCGGGGGACATCGAGGCCGAGTACGTGGTGAACGCGACCGGCATGTGGGGCCGCG
AGTTCGGGGAGATCGCAGGGGTCGACGTCCCCCTCCAAGCACTGGCCCATTACTACGTTGTAACTGAGGCCATCAAGGAC
CTGCCACGGAACCTCCCAACCATCAAGAGCGGCGACGAGTACTCGTACGTCAAGGACGAGGCAGGCGCACTCATGGTGGG
CTTTTTTGAGCCTGGAAGCTACGCATGGGCGTCGAGGGGCATCCCCGAGAGCGACGGCTACATCCGACTTCCCGAGGACT
GGGACCACCTCGGTGACTTCTACGAAAGGATGATGTATCGAGTCCCGGTCCTCGCCGATGCCGGCATACGCTTGCACTTC
TGCGGCCCCGAAAGCTTCACCCCGGACGGCCAGTACCACCTGGGCGAGGCGCCTAACCTGCGCAACTATTTCGTAGCTGC
CGGCTTCAATTCCGTCGGGTTCCTTTCCGGGCCTGGCGCCGGATCTGTTCTCGCTGACTGGATCGTTGACGGATACAGTC
CCGTCGACCTCCCAGAGACCGACCTCGGACGGGTCCAAACCCACGAGACCAACCGCAGATTCCTCGAAGAGCGAGTCGTT
GAGTCACTTGATATCTCTTACGAGATCCACTGGCCCTTCCAGCAGCGAGAATCCGCCCGCCAACTACGAGTGAGCCCGTT
GTACGAACGAACCGACGCGGCCGGCGCGGTATTCGGAGAGCTCGCCGGCTGGGAGCGCGCCAACTGGTACGCCCCCGCAG
GCGTCGTGCGCCGCTACGAGTACTCCTTCGGACGCCCGAACTGGTTCGAGCACTCGGCGGCCGAGCACAACGCCATTCGC
GAAGCCGTCGGAATGATCGACACCTCGTCCTTCGGCAAGCTCCTGGTTCAAGGACGCGACGCTGTGAGTGTGCTGAACCG
ACTCTCGGTGAACCAGGTCGACGTGCCGATCGGACGCATCGTCTACACCCAGTGGCTCAACGACAACGCGGGCATCGAAG
CCGACGTGACCATCACCCGGGTCGGCGAAACTGAGTTTCTCGTCCTGTCCGGCCCAGCAACCATCAACCGAGACCTCGCT
CATCTCCGACGGCACATCGGTGACCAGTTCTGCACCGTCGCCGATGTCACAGGGACCATGGCCATGCTTGCCGTCATGGG
CCCGAATGCCCGTGACCTCCTCGGCCCGCTCACCGATGCAGACTTGTCGACCGAGGCGTTCCCCTTTGGGACGTCTCGGC
AGATCGACCTCGGCTTGACCCACGTCAGGGCTACTCGCGTGACTTACGTGGGCGAACTGGGATGGGAACTCCTGATCCCG
TCCGAGAGTGCAAGGCACATCTGGGACACGATCATGGACGCCGGCGAGCCGCACGGTCTCCGCAACGTCGGTTATCACGC
GATGAACTCGTTGCGGCTAGAGAAGGCCTATCGAAGCTGGGGGCATGACATCTCCGCAGGCGACAACCCGATCCAGGCGG
GCCTCTCATTCACTGTCAAGTGGGACAAGTCGTCGGGATTCGTCGGCCGCGAAGCGCTGGAGAAGGTGAAGAGTGAGGGC
GTCGCACGGCGTCTCGTGCAGTTCGTCCTGGAGGATCCGGAACCGCTCCTCTTCCACGACGAACCCATCTATCGCTTCGG
CGAGTTGGTCGGACGCGTCGCATCCACCCAGTACGGCCACACCCTCGGCGGGGCTGTTGCGCTTGGCTGGGTCGAAGCGT
CTGAGGTTGTACCGCGCACCTGGTTCGAGTCCGAGCCGTACGAGATCGAGGTAGGCGGCCGGCGCGTCCCCGCTCGAGCT
TCCTTGAGTCCCATGTATGACCCGAAGTCCGAAAGGCCCAAGCAGTGA

Upstream 100 bases:

>100_bases
TGATCGATCGCACAGTTTGGATCACACCCTTCTGTCACTAGATGCATAGCGAGGCTCCTCGGGCGCGGGCACTGTTGCTA
CCTGATCGAGAGGTGGCCTC

Downstream 100 bases:

>100_bases
CGAACGACCTCATCCTTACCCTGTCCTGCAAGGACCGGCCCGGCATTGTCGCGGCCGTGGCCGGGTTCCTCGCGGATCGG
GGCTTCTCCATCCGGGACAG

Product: FAD dependent oxidoreductase

Products: NA

Alternate protein names: Glycine cleavage system T protein [H]

Number of amino acids: Translated: 815; Mature: 814

Protein sequence:

>815_residues
MGEQQQPARAQVVIVGGGIIGTSTAYHLACRGWTDVVLLERNTLTSGTTWHAAGLVTQARGTWGTREVVQRSLDVFRNLE
HDTGFSTGFVKTGTMNLATSADRFDEMRQLASVVRGNGIDADLLDVDRTLELHPLLNSDGLYGSLYFPEDGRGSATDTTI
ALARGATSRGVRIIENVAVAGVMTAGDRVRGVRTTAGDIEAEYVVNATGMWGREFGEIAGVDVPLQALAHYYVVTEAIKD
LPRNLPTIKSGDEYSYVKDEAGALMVGFFEPGSYAWASRGIPESDGYIRLPEDWDHLGDFYERMMYRVPVLADAGIRLHF
CGPESFTPDGQYHLGEAPNLRNYFVAAGFNSVGFLSGPGAGSVLADWIVDGYSPVDLPETDLGRVQTHETNRRFLEERVV
ESLDISYEIHWPFQQRESARQLRVSPLYERTDAAGAVFGELAGWERANWYAPAGVVRRYEYSFGRPNWFEHSAAEHNAIR
EAVGMIDTSSFGKLLVQGRDAVSVLNRLSVNQVDVPIGRIVYTQWLNDNAGIEADVTITRVGETEFLVLSGPATINRDLA
HLRRHIGDQFCTVADVTGTMAMLAVMGPNARDLLGPLTDADLSTEAFPFGTSRQIDLGLTHVRATRVTYVGELGWELLIP
SESARHIWDTIMDAGEPHGLRNVGYHAMNSLRLEKAYRSWGHDISAGDNPIQAGLSFTVKWDKSSGFVGREALEKVKSEG
VARRLVQFVLEDPEPLLFHDEPIYRFGELVGRVASTQYGHTLGGAVALGWVEASEVVPRTWFESEPYEIEVGGRRVPARA
SLSPMYDPKSERPKQ

Sequences:

>Translated_815_residues
MGEQQQPARAQVVIVGGGIIGTSTAYHLACRGWTDVVLLERNTLTSGTTWHAAGLVTQARGTWGTREVVQRSLDVFRNLE
HDTGFSTGFVKTGTMNLATSADRFDEMRQLASVVRGNGIDADLLDVDRTLELHPLLNSDGLYGSLYFPEDGRGSATDTTI
ALARGATSRGVRIIENVAVAGVMTAGDRVRGVRTTAGDIEAEYVVNATGMWGREFGEIAGVDVPLQALAHYYVVTEAIKD
LPRNLPTIKSGDEYSYVKDEAGALMVGFFEPGSYAWASRGIPESDGYIRLPEDWDHLGDFYERMMYRVPVLADAGIRLHF
CGPESFTPDGQYHLGEAPNLRNYFVAAGFNSVGFLSGPGAGSVLADWIVDGYSPVDLPETDLGRVQTHETNRRFLEERVV
ESLDISYEIHWPFQQRESARQLRVSPLYERTDAAGAVFGELAGWERANWYAPAGVVRRYEYSFGRPNWFEHSAAEHNAIR
EAVGMIDTSSFGKLLVQGRDAVSVLNRLSVNQVDVPIGRIVYTQWLNDNAGIEADVTITRVGETEFLVLSGPATINRDLA
HLRRHIGDQFCTVADVTGTMAMLAVMGPNARDLLGPLTDADLSTEAFPFGTSRQIDLGLTHVRATRVTYVGELGWELLIP
SESARHIWDTIMDAGEPHGLRNVGYHAMNSLRLEKAYRSWGHDISAGDNPIQAGLSFTVKWDKSSGFVGREALEKVKSEG
VARRLVQFVLEDPEPLLFHDEPIYRFGELVGRVASTQYGHTLGGAVALGWVEASEVVPRTWFESEPYEIEVGGRRVPARA
SLSPMYDPKSERPKQ
>Mature_814_residues
GEQQQPARAQVVIVGGGIIGTSTAYHLACRGWTDVVLLERNTLTSGTTWHAAGLVTQARGTWGTREVVQRSLDVFRNLEH
DTGFSTGFVKTGTMNLATSADRFDEMRQLASVVRGNGIDADLLDVDRTLELHPLLNSDGLYGSLYFPEDGRGSATDTTIA
LARGATSRGVRIIENVAVAGVMTAGDRVRGVRTTAGDIEAEYVVNATGMWGREFGEIAGVDVPLQALAHYYVVTEAIKDL
PRNLPTIKSGDEYSYVKDEAGALMVGFFEPGSYAWASRGIPESDGYIRLPEDWDHLGDFYERMMYRVPVLADAGIRLHFC
GPESFTPDGQYHLGEAPNLRNYFVAAGFNSVGFLSGPGAGSVLADWIVDGYSPVDLPETDLGRVQTHETNRRFLEERVVE
SLDISYEIHWPFQQRESARQLRVSPLYERTDAAGAVFGELAGWERANWYAPAGVVRRYEYSFGRPNWFEHSAAEHNAIRE
AVGMIDTSSFGKLLVQGRDAVSVLNRLSVNQVDVPIGRIVYTQWLNDNAGIEADVTITRVGETEFLVLSGPATINRDLAH
LRRHIGDQFCTVADVTGTMAMLAVMGPNARDLLGPLTDADLSTEAFPFGTSRQIDLGLTHVRATRVTYVGELGWELLIPS
ESARHIWDTIMDAGEPHGLRNVGYHAMNSLRLEKAYRSWGHDISAGDNPIQAGLSFTVKWDKSSGFVGREALEKVKSEGV
ARRLVQFVLEDPEPLLFHDEPIYRFGELVGRVASTQYGHTLGGAVALGWVEASEVVPRTWFESEPYEIEVGGRRVPARAS
LSPMYDPKSERPKQ

Specific function: The glycine cleavage system catalyzes the degradation of glycine [H]

COG id: COG0404

COG function: function code E; Glycine cleavage system T protein (aminomethyltransferase)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gcvT family [H]

Homologues:

Organism=Homo sapiens, GI197927446, Length=857, Percent_Identity=37.2228704784131, Blast_Score=527, Evalue=1e-149,
Organism=Homo sapiens, GI21361378, Length=857, Percent_Identity=37.2228704784131, Blast_Score=527, Evalue=1e-149,
Organism=Homo sapiens, GI194306651, Length=820, Percent_Identity=35.9756097560976, Blast_Score=498, Evalue=1e-140,
Organism=Homo sapiens, GI24797151, Length=820, Percent_Identity=33.6585365853659, Blast_Score=448, Evalue=1e-126,
Organism=Homo sapiens, GI257796258, Length=371, Percent_Identity=25.8760107816712, Blast_Score=92, Evalue=2e-18,
Organism=Homo sapiens, GI44662838, Length=371, Percent_Identity=25.8760107816712, Blast_Score=92, Evalue=2e-18,
Organism=Homo sapiens, GI257796256, Length=303, Percent_Identity=27.0627062706271, Blast_Score=83, Evalue=1e-15,
Organism=Homo sapiens, GI257796254, Length=208, Percent_Identity=29.8076923076923, Blast_Score=71, Evalue=4e-12,
Organism=Escherichia coli, GI1789272, Length=359, Percent_Identity=27.0194986072423, Blast_Score=105, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI32563613, Length=852, Percent_Identity=32.6291079812207, Blast_Score=378, Evalue=1e-105,
Organism=Caenorhabditis elegans, GI71994045, Length=826, Percent_Identity=29.2978208232446, Blast_Score=308, Evalue=9e-84,
Organism=Caenorhabditis elegans, GI71994052, Length=833, Percent_Identity=29.0516206482593, Blast_Score=305, Evalue=7e-83,
Organism=Caenorhabditis elegans, GI17560118, Length=399, Percent_Identity=23.3082706766917, Blast_Score=83, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17541536, Length=439, Percent_Identity=26.4236902050114, Blast_Score=82, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6320222, Length=237, Percent_Identity=26.1603375527426, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI28571104, Length=841, Percent_Identity=35.3151010701546, Blast_Score=501, Evalue=1e-141,
Organism=Drosophila melanogaster, GI20130091, Length=858, Percent_Identity=32.4009324009324, Blast_Score=422, Evalue=1e-118,
Organism=Drosophila melanogaster, GI20129441, Length=340, Percent_Identity=28.2352941176471, Blast_Score=102, Evalue=9e-22,

Paralogues:

None

Copy number: 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013977
- InterPro:   IPR006222
- InterPro:   IPR006223
- InterPro:   IPR022903 [H]

Pfam domain/function: PF01571 GCV_T; PF08669 GCV_T_C [H]

EC number: =2.1.2.10 [H]

Molecular weight: Translated: 89721; Mature: 89589

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGEQQQPARAQVVIVGGGIIGTSTAYHLACRGWTDVVLLERNTLTSGTTWHAAGLVTQAR
CCCCCCCCCEEEEEEECCEEECCCEEEEEECCCCEEEEEECCCCCCCCCEEHHCEEEECC
GTWGTREVVQRSLDVFRNLEHDTGFSTGFVKTGTMNLATSADRFDEMRQLASVVRGNGID
CCCCHHHHHHHHHHHHHCCCCCCCCCCCEEEECCEEECCCHHHHHHHHHHHHHHCCCCCC
ADLLDVDRTLELHPLLNSDGLYGSLYFPEDGRGSATDTTIALARGATSRGVRIIENVAVA
CHHCCCCCCEEEEECCCCCCCEEEEECCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHH
GVMTAGDRVRGVRTTAGDIEAEYVVNATGMWGREFGEIAGVDVPLQALAHYYVVTEAIKD
EEEECCCCCCCEEECCCCCEEEEEEECCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHH
LPRNLPTIKSGDEYSYVKDEAGALMVGFFEPGSYAWASRGIPESDGYIRLPEDWDHLGDF
HHHCCCCCCCCCCCCEEECCCCEEEEEEECCCCCCHHHCCCCCCCCEEECCCCHHHHHHH
YERMMYRVPVLADAGIRLHFCGPESFTPDGQYHLGEAPNLRNYFVAAGFNSVGFLSGPGA
HHHHHHHCCEEECCCEEEEEECCCCCCCCCCEECCCCCCCCCEEEEECCCCCCCCCCCCC
GSVLADWIVDGYSPVDLPETDLGRVQTHETNRRFLEERVVESLDISYEIHWPFQQRESAR
CHHHHHHHHCCCCCCCCCCCCCCCCEECHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHH
QLRVSPLYERTDAAGAVFGELAGWERANWYAPAGVVRRYEYSFGRPNWFEHSAAEHNAIR
HCCCCHHHHHCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHH
EAVGMIDTSSFGKLLVQGRDAVSVLNRLSVNQVDVPIGRIVYTQWLNDNAGIEADVTITR
HHHCCCCCCCHHHHEECCCHHHHHHHHCCCCCCCCCHHHEEEEEECCCCCCCEEEEEEEE
VGETEFLVLSGPATINRDLAHLRRHIGDQFCTVADVTGTMAMLAVMGPNARDLLGPLTDA
ECCEEEEEEECCCCCHHHHHHHHHHHCHHHEEHHHHHHHHHHHHHCCCCHHHHHCCCCCC
DLSTEAFPFGTSRQIDLGLTHVRATRVTYVGELGWELLIPSESARHIWDTIMDAGEPHGL
CCCCCCCCCCCCCEEECCCEEEEHHHEEEEECCCCEEEECCCHHHHHHHHHHCCCCCCCC
RNVGYHAMNSLRLEKAYRSWGHDISAGDNPIQAGLSFTVKWDKSSGFVGREALEKVKSEG
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEECCEEEEEEECCCCCCCCHHHHHHHHHHH
VARRLVQFVLEDPEPLLFHDEPIYRFGELVGRVASTQYGHTLGGAVALGWVEASEVVPRT
HHHHHHHHHHCCCCCEEECCCHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEHHHHCCCC
WFESEPYEIEVGGRRVPARASLSPMYDPKSERPKQ
CCCCCCEEEEECCEECCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
GEQQQPARAQVVIVGGGIIGTSTAYHLACRGWTDVVLLERNTLTSGTTWHAAGLVTQAR
CCCCCCCCEEEEEEECCEEECCCEEEEEECCCCEEEEEECCCCCCCCCEEHHCEEEECC
GTWGTREVVQRSLDVFRNLEHDTGFSTGFVKTGTMNLATSADRFDEMRQLASVVRGNGID
CCCCHHHHHHHHHHHHHCCCCCCCCCCCEEEECCEEECCCHHHHHHHHHHHHHHCCCCCC
ADLLDVDRTLELHPLLNSDGLYGSLYFPEDGRGSATDTTIALARGATSRGVRIIENVAVA
CHHCCCCCCEEEEECCCCCCCEEEEECCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHH
GVMTAGDRVRGVRTTAGDIEAEYVVNATGMWGREFGEIAGVDVPLQALAHYYVVTEAIKD
EEEECCCCCCCEEECCCCCEEEEEEECCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHH
LPRNLPTIKSGDEYSYVKDEAGALMVGFFEPGSYAWASRGIPESDGYIRLPEDWDHLGDF
HHHCCCCCCCCCCCCEEECCCCEEEEEEECCCCCCHHHCCCCCCCCEEECCCCHHHHHHH
YERMMYRVPVLADAGIRLHFCGPESFTPDGQYHLGEAPNLRNYFVAAGFNSVGFLSGPGA
HHHHHHHCCEEECCCEEEEEECCCCCCCCCCEECCCCCCCCCEEEEECCCCCCCCCCCCC
GSVLADWIVDGYSPVDLPETDLGRVQTHETNRRFLEERVVESLDISYEIHWPFQQRESAR
CHHHHHHHHCCCCCCCCCCCCCCCCEECHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHH
QLRVSPLYERTDAAGAVFGELAGWERANWYAPAGVVRRYEYSFGRPNWFEHSAAEHNAIR
HCCCCHHHHHCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHH
EAVGMIDTSSFGKLLVQGRDAVSVLNRLSVNQVDVPIGRIVYTQWLNDNAGIEADVTITR
HHHCCCCCCCHHHHEECCCHHHHHHHHCCCCCCCCCHHHEEEEEECCCCCCCEEEEEEEE
VGETEFLVLSGPATINRDLAHLRRHIGDQFCTVADVTGTMAMLAVMGPNARDLLGPLTDA
ECCEEEEEEECCCCCHHHHHHHHHHHCHHHEEHHHHHHHHHHHHHCCCCHHHHHCCCCCC
DLSTEAFPFGTSRQIDLGLTHVRATRVTYVGELGWELLIPSESARHIWDTIMDAGEPHGL
CCCCCCCCCCCCCEEECCCEEEEHHHEEEEECCCCEEEECCCHHHHHHHHHHCCCCCCCC
RNVGYHAMNSLRLEKAYRSWGHDISAGDNPIQAGLSFTVKWDKSSGFVGREALEKVKSEG
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEECCEEEEEEECCCCCCCCHHHHHHHHHHH
VARRLVQFVLEDPEPLLFHDEPIYRFGELVGRVASTQYGHTLGGAVALGWVEASEVVPRT
HHHHHHHHHHCCCCCEEECCCHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEHHHHCCCC
WFESEPYEIEVGGRRVPARASLSPMYDPKSERPKQ
CCCCCCEEEEECCEECCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA