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The map label for this gene is nuoE [H]

Identifier: 119714788

GI number: 119714788

Start: 554172

End: 554963

Strand: Direct

Name: nuoE [H]

Synonym: Noca_0524

Alternate gene names: 119714788

Gene position: 554172-554963 (Clockwise)

Preceding gene: 119714787

Following gene: 119714789

Centisome position: 11.11

GC content: 71.97

Gene sequence:

>792_bases
ATGAGCTTGACCCAGGAGACGTACGGCGAGCTGCAGGAGATCGCCGCCCGCTACCCGGAGCCCCGCTCCGGCCTGCTGCC
GATGCTCCACCTCGTCCAGTCCGCGGAGGGCCGGATCACGCCGGAGGGCATCGAGGCGTGTGCCGACCTGCTCGGCGTCA
CCGCAGCCGAGGTCAGCGGCGTCGCGACGTTCTACACCATGTACAAGCGCCGCCCGGTCGGCGACTACCACGTCGGCGTG
TGCACCAACACGCTGTGCGCGGTGATGGGCGGCGACGCGATCTTCGACCGGCTCAAGAGCGACCTGGGCGTCGGCAACGA
CGAGACGACCGAGGACGGCAAGATCACCCTCGAGCACATCGAGTGCAACGCGGCCTGCGACTACGCCCCTGTGATGATGG
TCAACTGGGAGTTCATGGACAACATGACCCCGGACACCGCCGCCCGGATCATCGACGACCTGCGCGCCGGCAACGAGGTC
CACTCGACCCGCGGCCCGCGGATCGTCACCTGGCGCGAGGCCGAGCGGGTCCTCGCCGGCTTCCCCGACGACCTCGCCGA
CGAGGGACCCGCGGCCGGGCGGGCCTCGCTGGTCGGTCTCGGCCTGGCCCGCGAGCGCGGCTGGGCCGCTCCCTCCTCCG
AGCAGGGTCCGGCCGCACACGACGTACCCGAGGAGCCGGCGCAGGTCGAGCAGGCAGCGGCCGACGCGAGCCCGCCGCCG
TCCGAGGCCGCCACGGTGGAGAAGGAGAGCGGCACGTCCGAGACGGCCGCCGAGAAGGGAGACGCCCAGTGA

Upstream 100 bases:

>100_bases
CCAACCTGCAGGCGACCAGCGTGATGGCCGAGGGCGGCATGGTCGCCGACGTCATCGTCGCGATCGCGTCCATCGATCCG
GTCATGGGAGGCGTCGACCG

Downstream 100 bases:

>100_bases
GCGATGCAGTGACCGACGTGCTCACTCCCGTCCTCACCGACAACTGGGACCAGGAGCGCTCCTGGACCCTGGCCGCCTAC
GAGTCACGCGGCGGCTACCG

Product: NADH dehydrogenase subunit E

Products: NA

Alternate protein names: NADH dehydrogenase I subunit E; NDH-1 subunit E [H]

Number of amino acids: Translated: 263; Mature: 262

Protein sequence:

>263_residues
MSLTQETYGELQEIAARYPEPRSGLLPMLHLVQSAEGRITPEGIEACADLLGVTAAEVSGVATFYTMYKRRPVGDYHVGV
CTNTLCAVMGGDAIFDRLKSDLGVGNDETTEDGKITLEHIECNAACDYAPVMMVNWEFMDNMTPDTAARIIDDLRAGNEV
HSTRGPRIVTWREAERVLAGFPDDLADEGPAAGRASLVGLGLARERGWAAPSSEQGPAAHDVPEEPAQVEQAAADASPPP
SEAATVEKESGTSETAAEKGDAQ

Sequences:

>Translated_263_residues
MSLTQETYGELQEIAARYPEPRSGLLPMLHLVQSAEGRITPEGIEACADLLGVTAAEVSGVATFYTMYKRRPVGDYHVGV
CTNTLCAVMGGDAIFDRLKSDLGVGNDETTEDGKITLEHIECNAACDYAPVMMVNWEFMDNMTPDTAARIIDDLRAGNEV
HSTRGPRIVTWREAERVLAGFPDDLADEGPAAGRASLVGLGLARERGWAAPSSEQGPAAHDVPEEPAQVEQAAADASPPP
SEAATVEKESGTSETAAEKGDAQ
>Mature_262_residues
SLTQETYGELQEIAARYPEPRSGLLPMLHLVQSAEGRITPEGIEACADLLGVTAAEVSGVATFYTMYKRRPVGDYHVGVC
TNTLCAVMGGDAIFDRLKSDLGVGNDETTEDGKITLEHIECNAACDYAPVMMVNWEFMDNMTPDTAARIIDDLRAGNEVH
STRGPRIVTWREAERVLAGFPDDLADEGPAAGRASLVGLGLARERGWAAPSSEQGPAAHDVPEEPAQVEQAAADASPPPS
EAATVEKESGTSETAAEKGDAQ

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be menaquinone. Couples the redox reaction to proton transloca

COG id: COG1905

COG function: function code C; NADH:ubiquinone oxidoreductase 24 kD subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 24 kDa subunit family [H]

Homologues:

Organism=Homo sapiens, GI222080062, Length=159, Percent_Identity=37.7358490566038, Blast_Score=119, Evalue=3e-27,
Organism=Escherichia coli, GI1788621, Length=139, Percent_Identity=32.3741007194245, Blast_Score=89, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17561328, Length=169, Percent_Identity=35.5029585798817, Blast_Score=113, Evalue=8e-26,
Organism=Drosophila melanogaster, GI18859877, Length=169, Percent_Identity=35.5029585798817, Blast_Score=115, Evalue=4e-26,
Organism=Drosophila melanogaster, GI21355353, Length=169, Percent_Identity=33.1360946745562, Blast_Score=101, Evalue=4e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002023
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF01257 Complex1_24kDa [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 27960; Mature: 27829

Theoretical pI: Translated: 4.13; Mature: 4.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLTQETYGELQEIAARYPEPRSGLLPMLHLVQSAEGRITPEGIEACADLLGVTAAEVSG
CCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
VATFYTMYKRRPVGDYHVGVCTNTLCAVMGGDAIFDRLKSDLGVGNDETTEDGKITLEHI
HHHHHHHHHCCCCCCEEHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCEEEEEE
ECNAACDYAPVMMVNWEFMDNMTPDTAARIIDDLRAGNEVHSTRGPRIVTWREAERVLAG
ECCCCCCCCCEEEEEHHHHCCCCHHHHHHHHHHHHCCCHHHHCCCCEEEEHHHHHHHHHC
FPDDLADEGPAAGRASLVGLGLARERGWAAPSSEQGPAAHDVPEEPAQVEQAAADASPPP
CCHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCC
SEAATVEKESGTSETAAEKGDAQ
CCCCEEECCCCCCHHHHCCCCCC
>Mature Secondary Structure 
SLTQETYGELQEIAARYPEPRSGLLPMLHLVQSAEGRITPEGIEACADLLGVTAAEVSG
CCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
VATFYTMYKRRPVGDYHVGVCTNTLCAVMGGDAIFDRLKSDLGVGNDETTEDGKITLEHI
HHHHHHHHHCCCCCCEEHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCEEEEEE
ECNAACDYAPVMMVNWEFMDNMTPDTAARIIDDLRAGNEVHSTRGPRIVTWREAERVLAG
ECCCCCCCCCEEEEEHHHHCCCCHHHHHHHHHHHHCCCHHHHCCCCEEEEHHHHHHHHHC
FPDDLADEGPAAGRASLVGLGLARERGWAAPSSEQGPAAHDVPEEPAQVEQAAADASPPP
CCHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCC
SEAATVEKESGTSETAAEKGDAQ
CCCCEEECCCCCCHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]