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The map label for this gene is ccdA [H]

Identifier: 119714766

GI number: 119714766

Start: 532958

End: 533719

Strand: Direct

Name: ccdA [H]

Synonym: Noca_0502

Alternate gene names: 119714766

Gene position: 532958-533719 (Clockwise)

Preceding gene: 119714765

Following gene: 119714767

Centisome position: 10.69

GC content: 72.44

Gene sequence:

>762_bases
ATGGGTGACTGGTTCCAGCAGACCGCGTTCTCCGGGTCGCTCGTCCTCGCCGTGCCGGTGGCCCTGATCGCCGGCCTGGT
GTCCTTCTTCTCCCCGTGCGTGATCCCGCTCCTGCCCGGCTACCTCTCCTACGCGACCGGCCTCTCCGGCGCCGACCTCG
CCACCGGCGCGGCCGGCACCCGGCGCGGCCGGATGCTACTCGGCTCGGTCCTGTTCGTGCTGGGCTTCTCGGTGGTCTTC
GTCGCCCTCGGCACCCTCTCCGGGGCGCTCGGGTCGTGGCTGGTCACCTGGCGCGACCAGATGACGTTCGTGCTCGGGCT
GCTGACGATCGTGCTCGGGCTGGCCTTCGCCGGCTGGCTGCCGTTCTTCCGGCGCGACTGGCGGGTGCACTCGGTGCCGG
CGGTCGGCCTCGCCGCCGCGCCGCTGCTCGGCTTCCTGTTCGGGCTCGGCTGGACGCCGTGCATCGGGCCCACTCTGAGC
GCGATCACCACGCTCTCCTTCACCGAGTCGACCGCCGGCCGCGGTGCCGTGCTCTCGGCCGTCTACGCCCTCGGCCTCGG
CCTGCCCTTCGTCCTCGCCGGCCTCGCCTACGAGAAGGCGCTCGCAACCGTCGGCTGGGTACGCCGCCACCAGGCCTGGG
TGATGCGCGCCGGCGGGCTGATGCTGGTGGCCGTCGGCCTGATGCTGGTGACCGGCTGGTGGGACCAGGCCGTCACCTGG
ATCCAGCTGCACCTGGTGAGCTCCTCGGAGACCGCGCTATGA

Upstream 100 bases:

>100_bases
GCCGTCATCACCGGGGAGATCCCCTCGAAGCAGACCCTGGTCGACGTCGTCGACGAGGTCGCTGCCAACGCCGCCGCGGA
GTCGGGCGGGGAGACCGCGG

Downstream 100 bases:

>100_bases
CCACCCCACGGCACCGCGCGCCTTCCCCCGCTCCGCTCCTCCAGCGCCCGGTTCCGCGGGGATCCCGGGTGAGGGCCGCA
CGATGAGCACCCCGACCCGC

Product: cytochrome c biogenesis protein, transmembrane region

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 253; Mature: 252

Protein sequence:

>253_residues
MGDWFQQTAFSGSLVLAVPVALIAGLVSFFSPCVIPLLPGYLSYATGLSGADLATGAAGTRRGRMLLGSVLFVLGFSVVF
VALGTLSGALGSWLVTWRDQMTFVLGLLTIVLGLAFAGWLPFFRRDWRVHSVPAVGLAAAPLLGFLFGLGWTPCIGPTLS
AITTLSFTESTAGRGAVLSAVYALGLGLPFVLAGLAYEKALATVGWVRRHQAWVMRAGGLMLVAVGLMLVTGWWDQAVTW
IQLHLVSSSETAL

Sequences:

>Translated_253_residues
MGDWFQQTAFSGSLVLAVPVALIAGLVSFFSPCVIPLLPGYLSYATGLSGADLATGAAGTRRGRMLLGSVLFVLGFSVVF
VALGTLSGALGSWLVTWRDQMTFVLGLLTIVLGLAFAGWLPFFRRDWRVHSVPAVGLAAAPLLGFLFGLGWTPCIGPTLS
AITTLSFTESTAGRGAVLSAVYALGLGLPFVLAGLAYEKALATVGWVRRHQAWVMRAGGLMLVAVGLMLVTGWWDQAVTW
IQLHLVSSSETAL
>Mature_252_residues
GDWFQQTAFSGSLVLAVPVALIAGLVSFFSPCVIPLLPGYLSYATGLSGADLATGAAGTRRGRMLLGSVLFVLGFSVVFV
ALGTLSGALGSWLVTWRDQMTFVLGLLTIVLGLAFAGWLPFFRRDWRVHSVPAVGLAAAPLLGFLFGLGWTPCIGPTLSA
ITTLSFTESTAGRGAVLSAVYALGLGLPFVLAGLAYEKALATVGWVRRHQAWVMRAGGLMLVAVGLMLVTGWWDQAVTWI
QLHLVSSSETAL

Specific function: Cytochrome c oxidase activity is partially restored by mutations in bdbC or bdbD that are defective in the synthesis of disulfide bond containing proteins. The same mutations abrogate the need for CcdA in sporulation [H]

COG id: COG0785

COG function: function code O; Cytochrome c biogenesis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DsbD family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003834 [H]

Pfam domain/function: PF02683 DsbD [H]

EC number: NA

Molecular weight: Translated: 26632; Mature: 26501

Theoretical pI: Translated: 9.69; Mature: 9.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHEEEECCCCCCC
>Mature Secondary Structure 
GDWFQQTAFSGSLVLAVPVALIAGLVSFFSPCVIPLLPGYLSYATGLSGADLATGAAGT
CCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHCCCCCC
RRGRMLLGSVLFVLGFSVVFVALGTLSGALGSWLVTWRDQMTFVLGLLTIVLGLAFAGWL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PFFRRDWRVHSVPAVGLAAAPLLGFLFGLGWTPCIGPTLSAITTLSFTESTAGRGAVLSA
HHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHH
VYALGLGLPFVLAGLAYEKALATVGWVRRHQAWVMRAGGLMLVAVGLMLVTGWWDQAVTW
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHH
IQLHLVSSSETAL
HHEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8969507; 9068642; 9384377; 10781554; 11844773 [H]