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The map label for this gene is frlC [C]

Identifier: 119714740

GI number: 119714740

Start: 507474

End: 508262

Strand: Direct

Name: frlC [C]

Synonym: Noca_0476

Alternate gene names: 119714740

Gene position: 507474-508262 (Clockwise)

Preceding gene: 119714739

Following gene: 119714741

Centisome position: 10.18

GC content: 70.85

Gene sequence:

>789_bases
ATGGCCCCACGCGTCGGACTCTCCACCGTCTCGGTCTACCCCGAGTCCTCCGCCCATGCCTTCGCCTACGCGAGTGCGCT
CGGTTACGACACCATCGAGGTGATGGTCGGGATCGACGCGCTCAGCCAGCAGACCTCCGCGATCCAGCAGCTCTCCGCAC
ACCACGGCGTACCGGTGTCCGCGGTGCACGCGCCCTGCCTGCTGTTCACGCAGCGGGTCTGGGGCACCGAGCCGTGGGGC
AAGCTCGAGCGCTCCGCGGAGATGGCGGCGGCGCTCGGGGCCGAGGTCGTCGTGGTCCATCCGCCGTTCCGCTGGCAGAA
GAGCTATGCCCGCGACTTCGTGGACGGCATCGCCGCGCTCGAGGAGTCCACCGGCATCGCGTTCGCGGTGGAGAACATGT
ATCCCTGGCGTGCCTCCAGCCGCGGCATGGAGATGTACCTGCCCGGCTGGGACCCCTCTTCCGAGCCGTACGCCAACACC
ACCATCGACCTCTCCCACGCGGCCATCGCGCGGTCCGACCCGGTCGGGATGGCCGAGCGTCTCGGCGACCGGTTGCGGCA
CATCCACCTGACCGACGGCACCGGCTCGGCCAAGGACGAGCACCTGGTCCCCGGTCGGGGATCGATCGGCGCCGCCGCGT
TCCTGCGGCACCTGGCGGCGGCCGGGTTCGGTGGTGAGATCGTCGTCGAGATCAACACCCGCAAGTGCCGCGACGCCGCG
GCCCGCGAGGTCGACCTGCGCGAGTCCCTCGAGTTCGCGCGCGAGCACTCCGTCGTGGGGACGCCGTGA

Upstream 100 bases:

>100_bases
TGGACATCTTCGGGCTCGAGCTCCTGGAGGTCTGCCCCTGGGCCCTGCGGGAGGGCGTGATCCTCGAACGGCTCGACCAG
ATCAGCGTGCTCGGCTAGCC

Downstream 100 bases:

>100_bases
CGGATCCCGCGACGCGGGCGGCCCCCCGTCGAGGTCGTCGGCCGGGGACCCCGGACACCCGTGCGGCGATCCTCGCCGCG
GCCCGGGAGCTCTTCGCGGC

Product: xylose isomerase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 262; Mature: 261

Protein sequence:

>262_residues
MAPRVGLSTVSVYPESSAHAFAYASALGYDTIEVMVGIDALSQQTSAIQQLSAHHGVPVSAVHAPCLLFTQRVWGTEPWG
KLERSAEMAAALGAEVVVVHPPFRWQKSYARDFVDGIAALEESTGIAFAVENMYPWRASSRGMEMYLPGWDPSSEPYANT
TIDLSHAAIARSDPVGMAERLGDRLRHIHLTDGTGSAKDEHLVPGRGSIGAAAFLRHLAAAGFGGEIVVEINTRKCRDAA
AREVDLRESLEFAREHSVVGTP

Sequences:

>Translated_262_residues
MAPRVGLSTVSVYPESSAHAFAYASALGYDTIEVMVGIDALSQQTSAIQQLSAHHGVPVSAVHAPCLLFTQRVWGTEPWG
KLERSAEMAAALGAEVVVVHPPFRWQKSYARDFVDGIAALEESTGIAFAVENMYPWRASSRGMEMYLPGWDPSSEPYANT
TIDLSHAAIARSDPVGMAERLGDRLRHIHLTDGTGSAKDEHLVPGRGSIGAAAFLRHLAAAGFGGEIVVEINTRKCRDAA
AREVDLRESLEFAREHSVVGTP
>Mature_261_residues
APRVGLSTVSVYPESSAHAFAYASALGYDTIEVMVGIDALSQQTSAIQQLSAHHGVPVSAVHAPCLLFTQRVWGTEPWGK
LERSAEMAAALGAEVVVVHPPFRWQKSYARDFVDGIAALEESTGIAFAVENMYPWRASSRGMEMYLPGWDPSSEPYANTT
IDLSHAAIARSDPVGMAERLGDRLRHIHLTDGTGSAKDEHLVPGRGSIGAAAFLRHLAAAGFGGEIVVEINTRKCRDAAA
REVDLRESLEFAREHSVVGTP

Specific function: Not Clear, May Be Involved In An Isomerization Step. [C]

COG id: COG1082

COG function: function code G; Sugar phosphate isomerases/epimerases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: To M.leprae ML2432 and M.tuberculosis Rv0498 [H]

Homologues:

None

Paralogues:

None

Copy number: 180 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013022
- InterPro:   IPR012307 [H]

Pfam domain/function: PF01261 AP_endonuc_2 [H]

EC number: NA

Molecular weight: Translated: 28192; Mature: 28061

Theoretical pI: Translated: 5.94; Mature: 5.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAPRVGLSTVSVYPESSAHAFAYASALGYDTIEVMVGIDALSQQTSAIQQLSAHHGVPVS
CCCCCCCEEEEECCCCCCHHHHHHHHHCCCHHHEEECHHHHHHHHHHHHHHHHHCCCCHH
AVHAPCLLFTQRVWGTEPWGKLERSAEMAAALGAEVVVVHPPFRWQKSYARDFVDGIAAL
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHH
EESTGIAFAVENMYPWRASSRGMEMYLPGWDPSSEPYANTTIDLSHAAIARSDPVGMAER
HHCCCEEEEECCCCCCCCCCCCCEEEECCCCCCCCCCCCCEEECHHHHHCCCCCCCHHHH
LGDRLRHIHLTDGTGSAKDEHLVPGRGSIGAAAFLRHLAAAGFGGEIVVEINTRKCRDAA
HHHHHEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEEECCCHHHHHH
AREVDLRESLEFAREHSVVGTP
HHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
APRVGLSTVSVYPESSAHAFAYASALGYDTIEVMVGIDALSQQTSAIQQLSAHHGVPVS
CCCCCCEEEEECCCCCCHHHHHHHHHCCCHHHEEECHHHHHHHHHHHHHHHHHCCCCHH
AVHAPCLLFTQRVWGTEPWGKLERSAEMAAALGAEVVVVHPPFRWQKSYARDFVDGIAAL
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHH
EESTGIAFAVENMYPWRASSRGMEMYLPGWDPSSEPYANTTIDLSHAAIARSDPVGMAER
HHCCCEEEEECCCCCCCCCCCCCEEEECCCCCCCCCCCCCEEECHHHHHCCCCCCCHHHH
LGDRLRHIHLTDGTGSAKDEHLVPGRGSIGAAAFLRHLAAAGFGGEIVVEINTRKCRDAA
HHHHHEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEEECCCHHHHHH
AREVDLRESLEFAREHSVVGTP
HHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]