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The map label for this gene is dacC [H]

Identifier: 119714703

GI number: 119714703

Start: 470027

End: 471409

Strand: Direct

Name: dacC [H]

Synonym: Noca_0439

Alternate gene names: 119714703

Gene position: 470027-471409 (Clockwise)

Preceding gene: 119714701

Following gene: 119714704

Centisome position: 9.43

GC content: 78.24

Gene sequence:

>1383_bases
GTGGGCGGACGTGACCGAGACCACCCCACCCGGGGCGCCCGTCTCGCGGCCTGGCTGCCCGTCGCCCTGGTGCTCGCCGT
CCTGGCGGCGGCCGGCCTCGTGCTCTGGCTCGACCCGCCGGCCTCGCCGCCCGAGGAGGAGCCGGCCGCGGTCCCGCCGC
CCGCGGGGCTCACCGTCCAGCCCCTCGTGGCGCCGGACCCGGTCGCCGAGCCGGCGAGCGGGGTGCCCGATCCCGGGAAG
GTACGCCGGGCCCTCGCGCCGCTGCTCCGCGACGCCGACCTGGGCCCCCACGTCCTCGCCACCGTGGCCGGCCTCGACGG
CACGCTGCTCTACTCCAGCGGCACCGGCTCGGCCACGCCCGCCTCGACCCTCAAGCTGCTGACCGCGGCAGCGGCCCTCG
AGACCCTCGGCCCCGATCACACCTTCGCCACGACGGTCGTCGACGCCGGACCGCGGCGGGTCGTGCTGGTCGGCGGCGGC
GACCCGCTGCTCGACCGCAAGGACGTCACCCGGCTGGCCCGCGACACCGCCACCGCCCTCGCCGCCACGGGCCGCACGCG
CGTGCGGGTCGACTACGACACCGGCCTGTTCCGCGGCCCCGAGGTCAGCCCGCACTGGCCCGCCGGCTACCTGCCGGACG
GCGTCGTCGCGCCGATCACTCCGCTCTGGATCGACGAGGGTCGCCCCGAGGACGGCTTCGGCCGGGTCGCGGACCCAGCC
GCGGTCGCGGCAGCGGCGTACGCCAAGGCGCTGGCTCGCGCCGGCGTCACCGTGCTCGGGCCCCAGCGCGAGGCGGCGGC
GCCCGCCGACGTCGCGGAGCTGGCCCGCACCGACAGCCTCCCGCTCGACCGGATCGTCGAGCACACCCTGGCGACCAGCG
ACAACGAGGCCGCCGAGGTGCTCGCCCGCCACGTGGGCCTCGCGACCTCCGGCGACGGGTCGTTCGCCGGCGGCGCCCGG
GCCCTGCTGCGGGTGCTCGACGGGCTCGGGGTCCCCACGCAGGGCACCACGACGTACGACGGCAGTGGGCTCTCCCGGGA
GGACCGGCTCGACCCCGACACGCTCACGGCGGTGCTCGAGCTCGCCGCGTCGCCCGAGCAGCCCGACCTCCGGGCGGTGC
TCACCGGGCTGCCGGTCGCCGGCTTCACCGGCTCCCTCACCGAGCGGTTCGCCGGGCCCGACGACCAGGGCCGCGGCCTG
GTCCGGGCGAAGACCGGGACGCTGTCGGGGGTGAGCAGCCTGGCCGGGATCGTGACCGACCGCGAGGGCCGGCCGATGGT
GTTCGCGCTGCTCGCCGACCGGATCGACCTGGTCGACACCCTGGACGCCCGAGCCGCCCTGGACGGCGCGACCGGTGCCC
TCGCCGGCTGTCGCTGCGGCTGA

Upstream 100 bases:

>100_bases
TCGTCAAGGGCCATCGTCAAAGGTCTGTGGGCCCGCGCGACGGGCTGGGGTCAGTCTCGCGCACAATGGCAGCAATTGCG
CACCCGGGAAGGGGTCGTTC

Downstream 100 bases:

>100_bases
CTTCCTGGCCGGGCGTGTGGCGGACGCGGGTACCGTCACCGCATGAGTAAGCACTCCGGCCCCGAGCTGGTCGACTGGGA
CCTCGCGGTCGCCCTCGGCT

Product: D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase

Products: NA

Alternate protein names: DD-carboxypeptidase; DD-peptidase; Penicillin-binding protein 4a; PBP-4a [H]

Number of amino acids: Translated: 460; Mature: 459

Protein sequence:

>460_residues
MGGRDRDHPTRGARLAAWLPVALVLAVLAAAGLVLWLDPPASPPEEEPAAVPPPAGLTVQPLVAPDPVAEPASGVPDPGK
VRRALAPLLRDADLGPHVLATVAGLDGTLLYSSGTGSATPASTLKLLTAAAALETLGPDHTFATTVVDAGPRRVVLVGGG
DPLLDRKDVTRLARDTATALAATGRTRVRVDYDTGLFRGPEVSPHWPAGYLPDGVVAPITPLWIDEGRPEDGFGRVADPA
AVAAAAYAKALARAGVTVLGPQREAAAPADVAELARTDSLPLDRIVEHTLATSDNEAAEVLARHVGLATSGDGSFAGGAR
ALLRVLDGLGVPTQGTTTYDGSGLSREDRLDPDTLTAVLELAASPEQPDLRAVLTGLPVAGFTGSLTERFAGPDDQGRGL
VRAKTGTLSGVSSLAGIVTDREGRPMVFALLADRIDLVDTLDARAALDGATGALAGCRCG

Sequences:

>Translated_460_residues
MGGRDRDHPTRGARLAAWLPVALVLAVLAAAGLVLWLDPPASPPEEEPAAVPPPAGLTVQPLVAPDPVAEPASGVPDPGK
VRRALAPLLRDADLGPHVLATVAGLDGTLLYSSGTGSATPASTLKLLTAAAALETLGPDHTFATTVVDAGPRRVVLVGGG
DPLLDRKDVTRLARDTATALAATGRTRVRVDYDTGLFRGPEVSPHWPAGYLPDGVVAPITPLWIDEGRPEDGFGRVADPA
AVAAAAYAKALARAGVTVLGPQREAAAPADVAELARTDSLPLDRIVEHTLATSDNEAAEVLARHVGLATSGDGSFAGGAR
ALLRVLDGLGVPTQGTTTYDGSGLSREDRLDPDTLTAVLELAASPEQPDLRAVLTGLPVAGFTGSLTERFAGPDDQGRGL
VRAKTGTLSGVSSLAGIVTDREGRPMVFALLADRIDLVDTLDARAALDGATGALAGCRCG
>Mature_459_residues
GGRDRDHPTRGARLAAWLPVALVLAVLAAAGLVLWLDPPASPPEEEPAAVPPPAGLTVQPLVAPDPVAEPASGVPDPGKV
RRALAPLLRDADLGPHVLATVAGLDGTLLYSSGTGSATPASTLKLLTAAAALETLGPDHTFATTVVDAGPRRVVLVGGGD
PLLDRKDVTRLARDTATALAATGRTRVRVDYDTGLFRGPEVSPHWPAGYLPDGVVAPITPLWIDEGRPEDGFGRVADPAA
VAAAAYAKALARAGVTVLGPQREAAAPADVAELARTDSLPLDRIVEHTLATSDNEAAEVLARHVGLATSGDGSFAGGARA
LLRVLDGLGVPTQGTTTYDGSGLSREDRLDPDTLTAVLELAASPEQPDLRAVLTGLPVAGFTGSLTERFAGPDDQGRGLV
RAKTGTLSGVSSLAGIVTDREGRPMVFALLADRIDLVDTLDARAALDGATGALAGCRCG

Specific function: Catalyzes DD-carboxypeptidase and transpeptidation reactions [H]

COG id: COG2027

COG function: function code M; D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4)

Gene ontology:

Cell location: Secreted (Probable). Note=May be anchored in the membrane via a C-terminal amphiphatic alpha helix [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S13 family [H]

Homologues:

Organism=Escherichia coli, GI1789573, Length=199, Percent_Identity=35.678391959799, Blast_Score=85, Evalue=8e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR000667 [H]

Pfam domain/function: PF02113 Peptidase_S13 [H]

EC number: =3.4.16.4 [H]

Molecular weight: Translated: 46870; Mature: 46739

Theoretical pI: Translated: 4.64; Mature: 4.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
0.4 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.2 %Met     (Mature Protein)
0.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGGRDRDHPTRGARLAAWLPVALVLAVLAAAGLVLWLDPPASPPEEEPAAVPPPAGLTVQ
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCCCCCCCCEEE
PLVAPDPVAEPASGVPDPGKVRRALAPLLRDADLGPHVLATVAGLDGTLLYSSGTGSATP
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCEEEEECCCCCCCH
ASTLKLLTAAAALETLGPDHTFATTVVDAGPRRVVLVGGGDPLLDRKDVTRLARDTATAL
HHHHHHHHHHHHHHHCCCCCCEEEHEECCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHH
AATGRTRVRVDYDTGLFRGPEVSPHWPAGYLPDGVVAPITPLWIDEGRPEDGFGRVADPA
HHCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCHH
AVAAAAYAKALARAGVTVLGPQREAAAPADVAELARTDSLPLDRIVEHTLATSDNEAAEV
HHHHHHHHHHHHHCCCEEECCCHHCCCCHHHHHHHHCCCCCHHHHHHHHHCCCCCHHHHH
LARHVGLATSGDGSFAGGARALLRVLDGLGVPTQGTTTYDGSGLSREDRLDPDTLTAVLE
HHHHHCCEECCCCCCCHHHHHHHHHHHCCCCCCCCCEEECCCCCCHHCCCCHHHHHHHHH
LAASPEQPDLRAVLTGLPVAGFTGSLTERFAGPDDQGRGLVRAKTGTLSGVSSLAGIVTD
HHCCCCCCHHHHHHHCCCCCCCCCHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHHCC
REGRPMVFALLADRIDLVDTLDARAALDGATGALAGCRCG
CCCCCEEEEHHHHHHHHHHHHHHHHHHCCCCHHCCCCCCC
>Mature Secondary Structure 
GGRDRDHPTRGARLAAWLPVALVLAVLAAAGLVLWLDPPASPPEEEPAAVPPPAGLTVQ
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCCCCCCCCEEE
PLVAPDPVAEPASGVPDPGKVRRALAPLLRDADLGPHVLATVAGLDGTLLYSSGTGSATP
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCEEEEECCCCCCCH
ASTLKLLTAAAALETLGPDHTFATTVVDAGPRRVVLVGGGDPLLDRKDVTRLARDTATAL
HHHHHHHHHHHHHHHCCCCCCEEEHEECCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHH
AATGRTRVRVDYDTGLFRGPEVSPHWPAGYLPDGVVAPITPLWIDEGRPEDGFGRVADPA
HHCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCHH
AVAAAAYAKALARAGVTVLGPQREAAAPADVAELARTDSLPLDRIVEHTLATSDNEAAEV
HHHHHHHHHHHHHCCCEEECCCHHCCCCHHHHHHHHCCCCCHHHHHHHHHCCCCCHHHHH
LARHVGLATSGDGSFAGGARALLRVLDGLGVPTQGTTTYDGSGLSREDRLDPDTLTAVLE
HHHHHCCEECCCCCCCHHHHHHHHHHHCCCCCCCCCEEECCCCCCHHCCCCHHHHHHHHH
LAASPEQPDLRAVLTGLPVAGFTGSLTERFAGPDDQGRGLVRAKTGTLSGVSSLAGIVTD
HHCCCCCCHHHHHHHCCCCCCCCCHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHHCC
REGRPMVFALLADRIDLVDTLDARAALDGATGALAGCRCG
CCCCCEEEEHHHHHHHHHHHHHHHHHHCCCCHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7711903; 9384377 [H]