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The map label for this gene is 119714654

Identifier: 119714654

GI number: 119714654

Start: 420751

End: 422100

Strand: Reverse

Name: 119714654

Synonym: Noca_0389

Alternate gene names: NA

Gene position: 422100-420751 (Counterclockwise)

Preceding gene: 119714655

Following gene: 119714642

Centisome position: 8.47

GC content: 74.0

Gene sequence:

>1350_bases
GTGAGCGACGTCGTGGTGGTGGGCGCCGGGCTGTCCGGGCTGGCGGCCGCCCGGCGCCTGCAGGCGGCGGGCCGGTCCGT
CGTCGTGGTCGAGGCGCGGGACCGGGTCGGCGGGCGTACCGAGGCCGGGGCGCTCAGCGACGGGCAGTGGATCGAGCTCG
GTGGCCAGTGGGTCGGGCCCACCCAGGACCGGATGTACGAGCTCATCGCGGAGCTCGGCTTGGCGACGATCCCGACGTAC
AACGACGGCGACATCGTCTTCTCGCTGTGCGGGCGACACGGCCGGCTCGCCGGTCGCAAGGGCGCGGTGCCGCGGCTCAA
CCCGTTCGCGATCGCCGACCTCGCGCAGGGCACGCTGCGCTTCGCCCGGCTGGCCCGCCGGGTCGACCTCGACCGACCCT
GGGACACCGAGCGCGCCGCGGCCCTCGACGGGCAGACCTTCCGCACCTGGGTGCAGCGCAACCTGCGCACCCCGCAGGGC
CGCGCCTACTTCGAGCTCTACTGCGAGGCGGTCTTCTCCGCCGACCTCTCGGACCTCTCGCTGCTGCACGCGCTGTTCTA
CACGCACTCCGGCACCGACATGGACACGCTGATGGCTGTGGACCGGGGCGCGCAGCAGGACCGGATCGACGGCGGCTCGT
GGCGGATCAGCCAGCGCCTGGCGGAGGGTCTCGACGTCCGGCTCGGCCAGCCGGTCCGGTCGGTCGTCCAGGACGCGGCC
GGGGTCCGGGTCGTGACCCGTGACGGCACGTCGTACGACGCGGACCGGGTGATCATCACGCTCCCGCCGGCGCTCGCCGG
CCGGCTGGAGTACGACCCGCCGCTGCCCAGCTGGCGCGACCAGCTGACCCAGAAGGTGCCGGCCGGCAGCGTCTTCAAGG
TCTACGCCGTCTACCCGACGCCGTTCTGGCGCGAGGACGGGCTCAACGGGCAGGCCGGCTCGGACCTCGGCCCGGTGAAG
GTCACCTTCGACAACACCCCGCCCGGCTACGACCGTGGCATCCTGATGGGGTTCATCGAGGCCGCCGACGGCCGGGAGTG
GGCCCGCCGTACCCCTGAGGAGAGGCGGGCTGCGGTCGTCGACTGCTTCGTGCGCTACTTCGGTCCCCGGGCCGCCGAGC
CGCTGGAGTACGTCGAGCGCGACTGGATGGCCGAGGAGTTCACCCGCGGCTGCTACGGCGCCCACTTCGCTCCGGGCGTG
TGGACCGGGTTCGGCCACGCCCTGCGCGAGCCGGTCGGGCGGCTGCACTGGGCCGGCGCGGAGTGCTCGCCGGTCTGGAA
CGGCTACATGGAGGGCGCGGTCCGCTCGGGCGAGGCCACCGCCGACGAGGTGCACGCGCTGCTGGGGTGA

Upstream 100 bases:

>100_bases
GGGAGAAGTGGACCGCTGCGGCGGAGGCGGGGACCGGTGACACCCGGCCGGCGTGGGTGCGCCGGCGGTGGGCGGGCTTC
GAGCTGAAGGCGGTGGGTCG

Downstream 100 bases:

>100_bases
GCGGCGCCGCCGTACTGTAACGCCGTGTTACCCCGACTCCCGACCATGTTGCAACACGGTGGGAGGAGCGGGTAAACGGG
CGTTACAACAGATCGGCCGG

Product: amine oxidase

Products: RCHO; NH3; H2O2

Alternate protein names: NA

Number of amino acids: Translated: 449; Mature: 448

Protein sequence:

>449_residues
MSDVVVVGAGLSGLAAARRLQAAGRSVVVVEARDRVGGRTEAGALSDGQWIELGGQWVGPTQDRMYELIAELGLATIPTY
NDGDIVFSLCGRHGRLAGRKGAVPRLNPFAIADLAQGTLRFARLARRVDLDRPWDTERAAALDGQTFRTWVQRNLRTPQG
RAYFELYCEAVFSADLSDLSLLHALFYTHSGTDMDTLMAVDRGAQQDRIDGGSWRISQRLAEGLDVRLGQPVRSVVQDAA
GVRVVTRDGTSYDADRVIITLPPALAGRLEYDPPLPSWRDQLTQKVPAGSVFKVYAVYPTPFWREDGLNGQAGSDLGPVK
VTFDNTPPGYDRGILMGFIEAADGREWARRTPEERRAAVVDCFVRYFGPRAAEPLEYVERDWMAEEFTRGCYGAHFAPGV
WTGFGHALREPVGRLHWAGAECSPVWNGYMEGAVRSGEATADEVHALLG

Sequences:

>Translated_449_residues
MSDVVVVGAGLSGLAAARRLQAAGRSVVVVEARDRVGGRTEAGALSDGQWIELGGQWVGPTQDRMYELIAELGLATIPTY
NDGDIVFSLCGRHGRLAGRKGAVPRLNPFAIADLAQGTLRFARLARRVDLDRPWDTERAAALDGQTFRTWVQRNLRTPQG
RAYFELYCEAVFSADLSDLSLLHALFYTHSGTDMDTLMAVDRGAQQDRIDGGSWRISQRLAEGLDVRLGQPVRSVVQDAA
GVRVVTRDGTSYDADRVIITLPPALAGRLEYDPPLPSWRDQLTQKVPAGSVFKVYAVYPTPFWREDGLNGQAGSDLGPVK
VTFDNTPPGYDRGILMGFIEAADGREWARRTPEERRAAVVDCFVRYFGPRAAEPLEYVERDWMAEEFTRGCYGAHFAPGV
WTGFGHALREPVGRLHWAGAECSPVWNGYMEGAVRSGEATADEVHALLG
>Mature_448_residues
SDVVVVGAGLSGLAAARRLQAAGRSVVVVEARDRVGGRTEAGALSDGQWIELGGQWVGPTQDRMYELIAELGLATIPTYN
DGDIVFSLCGRHGRLAGRKGAVPRLNPFAIADLAQGTLRFARLARRVDLDRPWDTERAAALDGQTFRTWVQRNLRTPQGR
AYFELYCEAVFSADLSDLSLLHALFYTHSGTDMDTLMAVDRGAQQDRIDGGSWRISQRLAEGLDVRLGQPVRSVVQDAAG
VRVVTRDGTSYDADRVIITLPPALAGRLEYDPPLPSWRDQLTQKVPAGSVFKVYAVYPTPFWREDGLNGQAGSDLGPVKV
TFDNTPPGYDRGILMGFIEAADGREWARRTPEERRAAVVDCFVRYFGPRAAEPLEYVERDWMAEEFTRGCYGAHFAPGVW
TGFGHALREPVGRLHWAGAECSPVWNGYMEGAVRSGEATADEVHALLG

Specific function: Unknown

COG id: COG1231

COG function: function code E; Monoamine oxidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the flavin monoamine oxidase family [H]

Homologues:

Organism=Homo sapiens, GI38202207, Length=444, Percent_Identity=34.6846846846847, Blast_Score=266, Evalue=2e-71,
Organism=Homo sapiens, GI4557735, Length=455, Percent_Identity=33.1868131868132, Blast_Score=266, Evalue=2e-71,
Organism=Homo sapiens, GI116256451, Length=90, Percent_Identity=36.6666666666667, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001613
- InterPro:   IPR002937 [H]

Pfam domain/function: PF01593 Amino_oxidase [H]

EC number: 1.4.3.4

Molecular weight: Translated: 49225; Mature: 49094

Theoretical pI: Translated: 5.53; Mature: 5.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDVVVVGAGLSGLAAARRLQAAGRSVVVVEARDRVGGRTEAGALSDGQWIELGGQWVGP
CCCEEEECCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCEEEECCEECCC
TQDRMYELIAELGLATIPTYNDGDIVFSLCGRHGRLAGRKGAVPRLNPFAIADLAQGTLR
CHHHHHHHHHHCCCCCCCCCCCCCHHEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
FARLARRVDLDRPWDTERAAALDGQTFRTWVQRNLRTPQGRAYFELYCEAVFSADLSDLS
HHHHHHHCCCCCCCCCCHHHHCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCHHHHH
LLHALFYTHSGTDMDTLMAVDRGAQQDRIDGGSWRISQRLAEGLDVRLGQPVRSVVQDAA
HHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHCC
GVRVVTRDGTSYDADRVIITLPPALAGRLEYDPPLPSWRDQLTQKVPAGSVFKVYAVYPT
CEEEEEECCCCCCCCEEEEECCHHHHCCCCCCCCCCHHHHHHHHHCCCCCEEEEEEECCC
PFWREDGLNGQAGSDLGPVKVTFDNTPPGYDRGILMGFIEAADGREWARRTPEERRAAVV
CCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHCCCCHHHHCCCHHHHHHHH
DCFVRYFGPRAAEPLEYVERDWMAEEFTRGCYGAHFAPGVWTGFGHALREPVGRLHWAGA
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHEEECCC
ECSPVWNGYMEGAVRSGEATADEVHALLG
CCCHHHHHHHHHHCCCCCCCHHHHHHHCC
>Mature Secondary Structure 
SDVVVVGAGLSGLAAARRLQAAGRSVVVVEARDRVGGRTEAGALSDGQWIELGGQWVGP
CCEEEECCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCEEEECCEECCC
TQDRMYELIAELGLATIPTYNDGDIVFSLCGRHGRLAGRKGAVPRLNPFAIADLAQGTLR
CHHHHHHHHHHCCCCCCCCCCCCCHHEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
FARLARRVDLDRPWDTERAAALDGQTFRTWVQRNLRTPQGRAYFELYCEAVFSADLSDLS
HHHHHHHCCCCCCCCCCHHHHCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCHHHHH
LLHALFYTHSGTDMDTLMAVDRGAQQDRIDGGSWRISQRLAEGLDVRLGQPVRSVVQDAA
HHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHCC
GVRVVTRDGTSYDADRVIITLPPALAGRLEYDPPLPSWRDQLTQKVPAGSVFKVYAVYPT
CEEEEEECCCCCCCCEEEEECCHHHHCCCCCCCCCCHHHHHHHHHCCCCCEEEEEEECCC
PFWREDGLNGQAGSDLGPVKVTFDNTPPGYDRGILMGFIEAADGREWARRTPEERRAAVV
CCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHCCCCHHHHCCCHHHHHHHH
DCFVRYFGPRAAEPLEYVERDWMAEEFTRGCYGAHFAPGVWTGFGHALREPVGRLHWAGA
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHEEECCC
ECSPVWNGYMEGAVRSGEATADEVHALLG
CCCHHHHHHHHHHCCCCCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: RCH2NH2; H2O; O2

Specific reaction: RCH2NH2 + H2O + O2 = RCHO + NH3 + H2O2

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]