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The map label for this gene is sigE [H]

Identifier: 119714642

GI number: 119714642

Start: 404073

End: 404597

Strand: Reverse

Name: sigE [H]

Synonym: Noca_0377

Alternate gene names: 119714642

Gene position: 404597-404073 (Counterclockwise)

Preceding gene: 119714654

Following gene: 119714641

Centisome position: 8.11

GC content: 74.48

Gene sequence:

>525_bases
ATGGAAGCCACGACGGACGCCCCGTCGCACCCCGACTTCGCGGACTTCGCGGCGGTGCAGAGCGGGCCGCTGCTGGGCCT
GGCCCACGCCCTGACGGCCAACCCGCACGACGCCTGGGACCTGACCCAGGAGACACTCGCGCGGATCGGCGAGCGGTGGG
GCCGGACCCGGATCGAGGAGCCGGCGGCGTACGCACGGACGGTGATGGTGCGCCTCAACATCGACCGGATCCGGCGGCTT
CGCCGCGAGCTCCCGCTCCTGGGGACGCCGCGGGAGGAGGCGCCGGTCGAGGTGGTGGGCCAGACCGACGCGTGGCTGGT
CGAGGCGCTCGCGACGCTGTCGCCGCGGCAGCGCACCGCGTTGGCGCTGCGCTACGTCGAGGACCTCGACGTGCGCGGCA
TCGCCCAGCGGATGGGCTGCTCGGAAGGCACCGTCAAGAGCCAGCTGTCCCGCGGGACCGAGCGGCTCCGAGAACACGCA
CGCGAGCACGGCCCGCTGCGCGCCGCGGCGACACGAGAGGACTGA

Upstream 100 bases:

>100_bases
TGCCGGGCGGCACCCATTCCCGAGCATCCGTCAACGTTTCGCTCCGGCCCCCCGTCAAGGAACAGTAGGCGAGCAGCCGA
CGACCCTCGGGAGGACCTGG

Downstream 100 bases:

>100_bases
AGCGATGACCGAGCAGCAGATCAAGGAGGGCTACGCGCGCCTGGGCGATGCGCTGGCCCCGCCGTTGGACGTCACCGCGC
GCGTGCAGCGCCGCGTGGGC

Product: sigma-70, region 4 type 2

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 174; Mature: 174

Protein sequence:

>174_residues
MEATTDAPSHPDFADFAAVQSGPLLGLAHALTANPHDAWDLTQETLARIGERWGRTRIEEPAAYARTVMVRLNIDRIRRL
RRELPLLGTPREEAPVEVVGQTDAWLVEALATLSPRQRTALALRYVEDLDVRGIAQRMGCSEGTVKSQLSRGTERLREHA
REHGPLRAAATRED

Sequences:

>Translated_174_residues
MEATTDAPSHPDFADFAAVQSGPLLGLAHALTANPHDAWDLTQETLARIGERWGRTRIEEPAAYARTVMVRLNIDRIRRL
RRELPLLGTPREEAPVEVVGQTDAWLVEALATLSPRQRTALALRYVEDLDVRGIAQRMGCSEGTVKSQLSRGTERLREHA
REHGPLRAAATRED
>Mature_174_residues
MEATTDAPSHPDFADFAAVQSGPLLGLAHALTANPHDAWDLTQETLARIGERWGRTRIEEPAAYARTVMVRLNIDRIRRL
RRELPLLGTPREEAPVEVVGQTDAWLVEALATLSPRQRTALALRYVEDLDVRGIAQRMGCSEGTVKSQLSRGTERLREHA
REHGPLRAAATRED

Specific function: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is required for normal cell wall integrity; it is recruited by RNA polymerase to transcribe genes with

COG id: COG1595

COG function: function code K; DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sigma-70 factor family. ECF subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014284
- InterPro:   IPR014325
- InterPro:   IPR000838
- InterPro:   IPR007627
- InterPro:   IPR013249
- InterPro:   IPR013325
- InterPro:   IPR013324
- InterPro:   IPR011991 [H]

Pfam domain/function: PF04542 Sigma70_r2; PF08281 Sigma70_r4_2 [H]

EC number: NA

Molecular weight: Translated: 19377; Mature: 19377

Theoretical pI: Translated: 6.69; Mature: 6.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEATTDAPSHPDFADFAAVQSGPLLGLAHALTANPHDAWDLTQETLARIGERWGRTRIEE
CCCCCCCCCCCCHHHHHHHCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCC
PAAYARTVMVRLNIDRIRRLRRELPLLGTPREEAPVEVVGQTDAWLVEALATLSPRQRTA
HHHHHHHHHHEECHHHHHHHHHHCCCCCCCCCCCCEEEECCCHHHHHHHHHHCCCHHHHH
LALRYVEDLDVRGIAQRMGCSEGTVKSQLSRGTERLREHAREHGPLRAAATRED
HHHHHHHHCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MEATTDAPSHPDFADFAAVQSGPLLGLAHALTANPHDAWDLTQETLARIGERWGRTRIEE
CCCCCCCCCCCCHHHHHHHCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCC
PAAYARTVMVRLNIDRIRRLRRELPLLGTPREEAPVEVVGQTDAWLVEALATLSPRQRTA
HHHHHHHHHHEECHHHHHHHHHHCCCCCCCCCCCCEEEECCCHHHHHHHHHHCCCHHHHH
LALRYVEDLDVRGIAQRMGCSEGTVKSQLSRGTERLREHAREHGPLRAAATRED
HHHHHHHHCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8052622; 10411727; 12000953 [H]