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The map label for this gene is dnaX [H]

Identifier: 119714652

GI number: 119714652

Start: 417907

End: 419064

Strand: Direct

Name: dnaX [H]

Synonym: Noca_0387

Alternate gene names: 119714652

Gene position: 417907-419064 (Clockwise)

Preceding gene: 119714651

Following gene: 119714653

Centisome position: 8.38

GC content: 74.53

Gene sequence:

>1158_bases
ATGACCGTCTGGGACGGCCTCGTCGGGCAGCATCGGCCGAGCGAGGCGCTGCGCGCGGCCGCCCACGGGCAGGGCATGAG
CCACGCCTTCCTCTTCACCGGCCCGCCCGGCTCGGGTCGGTCCAACGCGGCCGTCGCCTTCGCGGCGGCGCTGCAGTGCG
AACGCCCCGAGGACCGCGGGTGCGGCGAGTGCCACGAGTGCCACACGGTGCTGACCGGCAGCCACGCCGACGTGGCGGTG
ATCCGCACCGAGAAGCTCTCCATCGGGGTCGACGAGATGCGCGACCTGGTGCGCCGCTCGGCCCTCGCCCCGGTCGGCCG
GCGCTGGCAGATCATGATCGTCGAGGACGCCGACCGGCTCACCGAGCGGGCGTGGAACGCGCTGCTCAAGGCGATCGAGG
AGCCCGCGGACCGCACCGTGTGGATGCTGTGCGCTCCCACGGTCGAGGACGTGCTGCCCACGGTCCGGTCGCGCTGCCGG
CTGGTCACGCTCACGACCCCGACGACCGACGACGTCGCCTCGTTCCTGGTCCGTGCGGACGGGGTCGACGCCGCGGTGGC
GTCGTACGCCGCCCGCGCGAGCCAGGGCCACATCGGCCGCGCCCGGGCGCTGGCCCGCGACGAGGCGACCCGCAACCGGC
GCCGCGAGGTGGTCGCGCTGCCCGCCCGGCTGGTCTCGCTGCGCGCCTGCATGGAGGCCGCCACCAGCCTCGCCGAGGTC
GCCAAGCAGGAGGCCGAGCTGGTGACCGGCGAGCTGGACGCGCGCGAGAAGGCCGACCTGGACGCGGCGTACGGCGTGGT
CGAGCGCGGCCGCCGCCCGCGGGAGTACGCACCCGCGCTGCGCGACCTCGAGAAGGACCAGAAGACCCGCGCCAAGCGGC
GCTACCTCGACGTCGTCGACCGGGGCCTGATGGACCTGGTGTCGGTCTACCGCGACGCGATCGCGGTCGCGACCGGCGCC
GCCGGCCTCCTGGTCAACGAGGAGATCCGCGGCGACGTCGAGCTGCTCGCCCGGGTGTCGACCCCCGAGGTCAACCTGCG
CCGGATCGCGGCGATCTTCGAGGCCCGCGAGCAGATGCTGGAGTTCAACGTGCAGCCGATGCTGGCGCTGGAGTCGATGA
TGGTCGCGCTCGTCGCGCCGGAGGTGCGCACCGGGTGA

Upstream 100 bases:

>100_bases
CGGACCACTACCTGGTGCTCGACGCCCGGGGCGACCGCGAGGAGATCGCCGGCCGGGTCCGCGACCGCGTCGCCCCCCTG
CTCGACCGGGCGGCCCGGCG

Downstream 100 bases:

>100_bases
GGCGGCTGCTGGTCGTCCTGGTGGTGGTCGCGCTGGTGGTCGGCGTCGGCGGTGTCGCCGTGCTCGTCGCCCTCGGCCCC
GGCGACCCGAGTGACCCCGG

Product: DNA polymerase III subunit delta'

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 385; Mature: 384

Protein sequence:

>385_residues
MTVWDGLVGQHRPSEALRAAAHGQGMSHAFLFTGPPGSGRSNAAVAFAAALQCERPEDRGCGECHECHTVLTGSHADVAV
IRTEKLSIGVDEMRDLVRRSALAPVGRRWQIMIVEDADRLTERAWNALLKAIEEPADRTVWMLCAPTVEDVLPTVRSRCR
LVTLTTPTTDDVASFLVRADGVDAAVASYAARASQGHIGRARALARDEATRNRRREVVALPARLVSLRACMEAATSLAEV
AKQEAELVTGELDAREKADLDAAYGVVERGRRPREYAPALRDLEKDQKTRAKRRYLDVVDRGLMDLVSVYRDAIAVATGA
AGLLVNEEIRGDVELLARVSTPEVNLRRIAAIFEAREQMLEFNVQPMLALESMMVALVAPEVRTG

Sequences:

>Translated_385_residues
MTVWDGLVGQHRPSEALRAAAHGQGMSHAFLFTGPPGSGRSNAAVAFAAALQCERPEDRGCGECHECHTVLTGSHADVAV
IRTEKLSIGVDEMRDLVRRSALAPVGRRWQIMIVEDADRLTERAWNALLKAIEEPADRTVWMLCAPTVEDVLPTVRSRCR
LVTLTTPTTDDVASFLVRADGVDAAVASYAARASQGHIGRARALARDEATRNRRREVVALPARLVSLRACMEAATSLAEV
AKQEAELVTGELDAREKADLDAAYGVVERGRRPREYAPALRDLEKDQKTRAKRRYLDVVDRGLMDLVSVYRDAIAVATGA
AGLLVNEEIRGDVELLARVSTPEVNLRRIAAIFEAREQMLEFNVQPMLALESMMVALVAPEVRTG
>Mature_384_residues
TVWDGLVGQHRPSEALRAAAHGQGMSHAFLFTGPPGSGRSNAAVAFAAALQCERPEDRGCGECHECHTVLTGSHADVAVI
RTEKLSIGVDEMRDLVRRSALAPVGRRWQIMIVEDADRLTERAWNALLKAIEEPADRTVWMLCAPTVEDVLPTVRSRCRL
VTLTTPTTDDVASFLVRADGVDAAVASYAARASQGHIGRARALARDEATRNRRREVVALPARLVSLRACMEAATSLAEVA
KQEAELVTGELDAREKADLDAAYGVVERGRRPREYAPALRDLEKDQKTRAKRRYLDVVDRGLMDLVSVYRDAIAVATGAA
GLLVNEEIRGDVELLARVSTPEVNLRRIAAIFEAREQMLEFNVQPMLALESMMVALVAPEVRTG

Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria [H]

COG id: COG0470

COG function: function code L; ATPase involved in DNA replication

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786676, Length=157, Percent_Identity=29.9363057324841, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1787341, Length=202, Percent_Identity=33.1683168316832, Blast_Score=65, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003959
- InterPro:   IPR001270
- InterPro:   IPR008921
- InterPro:   IPR022754
- InterPro:   IPR012763 [H]

Pfam domain/function: PF00004 AAA; PF12169 DNA_pol3_gamma3 [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 42093; Mature: 41961

Theoretical pI: Translated: 6.42; Mature: 6.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVWDGLVGQHRPSEALRAAAHGQGMSHAFLFTGPPGSGRSNAAVAFAAALQCERPEDRG
CCCCCCCCCCCCCHHHHHHHHCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHCCCCCCCC
CGECHECHTVLTGSHADVAVIRTEKLSIGVDEMRDLVRRSALAPVGRRWQIMIVEDADRL
CCCHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCCCCEEEEEECCHHHH
TERAWNALLKAIEEPADRTVWMLCAPTVEDVLPTVRSRCRLVTLTTPTTDDVASFLVRAD
HHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHCCEEEEEECCCHHHHHHHHHHCC
GVDAAVASYAARASQGHIGRARALARDEATRNRRREVVALPARLVSLRACMEAATSLAEV
CCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AKQEAELVTGELDAREKADLDAAYGVVERGRRPREYAPALRDLEKDQKTRAKRRYLDVVD
HHHHHHHHHCCCCCHHHHCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
RGLMDLVSVYRDAIAVATGAAGLLVNEEIRGDVELLARVSTPEVNLRRIAAIFEAREQML
HHHHHHHHHHHHHHHHHCCCCCEEECHHHHCCHHHHHCCCCCCHHHHHHHHHHHHHHHHH
EFNVQPMLALESMMVALVAPEVRTG
HCCCCHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TVWDGLVGQHRPSEALRAAAHGQGMSHAFLFTGPPGSGRSNAAVAFAAALQCERPEDRG
CCCCCCCCCCCCHHHHHHHHCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHCCCCCCCC
CGECHECHTVLTGSHADVAVIRTEKLSIGVDEMRDLVRRSALAPVGRRWQIMIVEDADRL
CCCHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCCCCEEEEEECCHHHH
TERAWNALLKAIEEPADRTVWMLCAPTVEDVLPTVRSRCRLVTLTTPTTDDVASFLVRAD
HHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHCCEEEEEECCCHHHHHHHHHHCC
GVDAAVASYAARASQGHIGRARALARDEATRNRRREVVALPARLVSLRACMEAATSLAEV
CCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AKQEAELVTGELDAREKADLDAAYGVVERGRRPREYAPALRDLEKDQKTRAKRRYLDVVD
HHHHHHHHHCCCCCHHHHCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
RGLMDLVSVYRDAIAVATGAAGLLVNEEIRGDVELLARVSTPEVNLRRIAAIFEAREQML
HHHHHHHHHHHHHHHHHCCCCCEEECHHHHCCHHHHHCCCCCCHHHHHHHHHHHHHHHHH
EFNVQPMLALESMMVALVAPEVRTG
HCCCCHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2124672; 7584024; 9384377; 2452406; 2468993; 1698458 [H]