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The map label for this gene is copA [H]

Identifier: 119714577

GI number: 119714577

Start: 330706

End: 332175

Strand: Reverse

Name: copA [H]

Synonym: Noca_0310

Alternate gene names: 119714577

Gene position: 332175-330706 (Counterclockwise)

Preceding gene: 119714582

Following gene: 119714570

Centisome position: 6.66

GC content: 74.01

Gene sequence:

>1470_bases
TTGCGCGGGACCGCCGCGCTGGGCGGAGCGACGGCACTCGCCGGACTCGCCTCGTGCAGCCGGTCCGGCGGTACCGCCGT
CGGTCCCACCGCGCCGGCCGTGACGGCCGCCGAGGACGCCCGCCGTCGAGCCGGCGGCCAGCTGGTGACGGCACGGCTCA
CGCCCCGCCCGGTGACGCTCGACCTGGGCGGGCGAGCGGTCGATACCTGGGCGTACGGCGACGCGGTCCCGGGTCCGCTG
CTCCGCGCCCGGGCGGGGGACCTGCTGCGCGTCGAGGTCGACAACCAGCTGCCCGTCGACACCAGCGTCCACTGGCACGG
CATCGCGCTGCGCAACGACATGGACGGCGTCCCCGGGGTCACCCAGGACCCGATCGGCGCCGCCGCGACGTTCCGGTACG
AGTTCACGGTCCCGGACCCCGGCACCTACTTCTACCACCCGCACTCGGGCGTCCAGCTCGACCGCGGCCTGTACGGCGTC
CTCCTGGTCGACGGCCCCGACGAGGAGGATGCCGACCAGGAGTGGGTCGTCGTCCTCGACGACTGGGTCGACGGCACCGG
TCGCACCCCGGACCAGGTGCTCGAGAGCCTGCGCGCAGGCGGGGGCGGCGGGCACGGGTCGATGGCCGGCATGGACCACG
GCTCGATGATGGGGGGCGGCGGGGGCATGCAGTCCCGGCTGCTCGGTGGTAGCGGGGACGTGCGCTACCCGCTGTACCTG
GTCAACGGGCGCACCGCGGACGACCCGGCCACCCTGCGGGGTCGACCGGGCCAGAAGGTCCGGATCCGAGTCGTGAACGC
GGGCTCGGACACGGCCTTCCGGGTGGCCGTCGGTGGGCACCGCCTGACCGTCACCCACAGTGACGGCTTCCCCGTCACGC
CGGTGTCCACCGACGCGCTGCTGATCGGCATGGGTGAGCGCTTCGACGTCACGGTGACCCTCGGCGACGGCGTCTTCGCG
CTGGTCGCGGTCGCGGAGGGGAAGAACGGCGGCGGCCTGGCGGTCGTGCGGACGGGCGCCGGCACCACCCCGGGGCCCGA
CGCGTGGGCCCGGCACCGCGGCCAGCCGGCGCTGCTCGGAGCCGACCTGACTCCGACCGAGTCCGTCCGGCTGCCGGACC
GGGCGGTCGACCGACGCCACGACCTGGTCCTGGCCGGCACCATGGCGAGCTACCGGTGGTCGATCAACGGGCGGATGTTC
CCCGACGACGAGCCGCTACCGGTGGCCGAGGGCGAACGCGTCCGCCTGCGGTTCGTGAACCGGTCGATGATGTTCCATCC
CATGCACGTCCACGGCCACACGTTCGCCCTCGCCACGGGCGGCGCCCGCAAGGACACCGTGATCGTGCGCCCGATGGAAG
CCCTCGAGGTCGACCTCGACGCCGACAACCCGGGTCAGTGGGCGGCGCACTGCCACAACATCTACCACGCGGAGAGCGGG
ATGATGACGACGCTGTCCTACCGGGCGTAG

Upstream 100 bases:

>100_bases
GGCGCTACGGCCATCGTCCGGATCGGAGCTCGCACTGAGCCGGGCCACGGAGCCGGCGAGCCCGAGGAGCGACATTCCCC
CGATCACCCGCCGCGCCCTC

Downstream 100 bases:

>100_bases
CGCACTACCGGCTGATAGGTCGTGAGCTGCAGCTAGGTTCTGCGCCGGGCGAGGACGGGGCGCAGCACCAGCGCGACGAC
GAGGCCACCGGCACCGATCA

Product: multicopper oxidase, type 3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 489; Mature: 489

Protein sequence:

>489_residues
MRGTAALGGATALAGLASCSRSGGTAVGPTAPAVTAAEDARRRAGGQLVTARLTPRPVTLDLGGRAVDTWAYGDAVPGPL
LRARAGDLLRVEVDNQLPVDTSVHWHGIALRNDMDGVPGVTQDPIGAAATFRYEFTVPDPGTYFYHPHSGVQLDRGLYGV
LLVDGPDEEDADQEWVVVLDDWVDGTGRTPDQVLESLRAGGGGGHGSMAGMDHGSMMGGGGGMQSRLLGGSGDVRYPLYL
VNGRTADDPATLRGRPGQKVRIRVVNAGSDTAFRVAVGGHRLTVTHSDGFPVTPVSTDALLIGMGERFDVTVTLGDGVFA
LVAVAEGKNGGGLAVVRTGAGTTPGPDAWARHRGQPALLGADLTPTESVRLPDRAVDRRHDLVLAGTMASYRWSINGRMF
PDDEPLPVAEGERVRLRFVNRSMMFHPMHVHGHTFALATGGARKDTVIVRPMEALEVDLDADNPGQWAAHCHNIYHAESG
MMTTLSYRA

Sequences:

>Translated_489_residues
MRGTAALGGATALAGLASCSRSGGTAVGPTAPAVTAAEDARRRAGGQLVTARLTPRPVTLDLGGRAVDTWAYGDAVPGPL
LRARAGDLLRVEVDNQLPVDTSVHWHGIALRNDMDGVPGVTQDPIGAAATFRYEFTVPDPGTYFYHPHSGVQLDRGLYGV
LLVDGPDEEDADQEWVVVLDDWVDGTGRTPDQVLESLRAGGGGGHGSMAGMDHGSMMGGGGGMQSRLLGGSGDVRYPLYL
VNGRTADDPATLRGRPGQKVRIRVVNAGSDTAFRVAVGGHRLTVTHSDGFPVTPVSTDALLIGMGERFDVTVTLGDGVFA
LVAVAEGKNGGGLAVVRTGAGTTPGPDAWARHRGQPALLGADLTPTESVRLPDRAVDRRHDLVLAGTMASYRWSINGRMF
PDDEPLPVAEGERVRLRFVNRSMMFHPMHVHGHTFALATGGARKDTVIVRPMEALEVDLDADNPGQWAAHCHNIYHAESG
MMTTLSYRA
>Mature_489_residues
MRGTAALGGATALAGLASCSRSGGTAVGPTAPAVTAAEDARRRAGGQLVTARLTPRPVTLDLGGRAVDTWAYGDAVPGPL
LRARAGDLLRVEVDNQLPVDTSVHWHGIALRNDMDGVPGVTQDPIGAAATFRYEFTVPDPGTYFYHPHSGVQLDRGLYGV
LLVDGPDEEDADQEWVVVLDDWVDGTGRTPDQVLESLRAGGGGGHGSMAGMDHGSMMGGGGGMQSRLLGGSGDVRYPLYL
VNGRTADDPATLRGRPGQKVRIRVVNAGSDTAFRVAVGGHRLTVTHSDGFPVTPVSTDALLIGMGERFDVTVTLGDGVFA
LVAVAEGKNGGGLAVVRTGAGTTPGPDAWARHRGQPALLGADLTPTESVRLPDRAVDRRHDLVLAGTMASYRWSINGRMF
PDDEPLPVAEGERVRLRFVNRSMMFHPMHVHGHTFALATGGARKDTVIVRPMEALEVDLDADNPGQWAAHCHNIYHAESG
MMTTLSYRA

Specific function: Could be involved in copper resistance. May have oxidase activity [H]

COG id: COG2132

COG function: function code Q; Putative multicopper oxidases

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multicopper oxidase family. CopA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786314, Length=554, Percent_Identity=24.9097472924188, Blast_Score=95, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17539950, Length=245, Percent_Identity=27.7551020408163, Blast_Score=81, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6320714, Length=502, Percent_Identity=21.9123505976096, Blast_Score=103, Evalue=6e-23,
Organism=Saccharomyces cerevisiae, GI6323703, Length=471, Percent_Identity=23.1422505307856, Blast_Score=96, Evalue=1e-20,
Organism=Saccharomyces cerevisiae, GI6321067, Length=252, Percent_Identity=26.984126984127, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI221330000, Length=253, Percent_Identity=30.8300395256917, Blast_Score=110, Evalue=3e-24,
Organism=Drosophila melanogaster, GI24585842, Length=253, Percent_Identity=30.8300395256917, Blast_Score=110, Evalue=3e-24,
Organism=Drosophila melanogaster, GI221329998, Length=253, Percent_Identity=30.8300395256917, Blast_Score=109, Evalue=3e-24,
Organism=Drosophila melanogaster, GI281360167, Length=253, Percent_Identity=30.8300395256917, Blast_Score=109, Evalue=3e-24,
Organism=Drosophila melanogaster, GI28574104, Length=288, Percent_Identity=27.7777777777778, Blast_Score=99, Evalue=5e-21,
Organism=Drosophila melanogaster, GI24650186, Length=245, Percent_Identity=27.7551020408163, Blast_Score=89, Evalue=8e-18,
Organism=Drosophila melanogaster, GI18859919, Length=254, Percent_Identity=29.5275590551181, Blast_Score=84, Evalue=3e-16,

Paralogues:

None

Copy number: 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001117
- InterPro:   IPR011706
- InterPro:   IPR011707
- InterPro:   IPR006376
- InterPro:   IPR002355
- InterPro:   IPR008972
- InterPro:   IPR006311 [H]

Pfam domain/function: PF00394 Cu-oxidase; PF07731 Cu-oxidase_2; PF07732 Cu-oxidase_3 [H]

EC number: NA

Molecular weight: Translated: 51531; Mature: 51531

Theoretical pI: Translated: 6.27; Mature: 6.27

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00080 MULTICOPPER_OXIDASE2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRGTAALGGATALAGLASCSRSGGTAVGPTAPAVTAAEDARRRAGGQLVTARLTPRPVTL
CCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCEECHHHHHHHCCCEEEEEEECCCEEEE
DLGGRAVDTWAYGDAVPGPLLRARAGDLLRVEVDNQLPVDTSVHWHGIALRNDMDGVPGV
ECCCEEEEEEECCCCCCCCHHHHCCCCEEEEEECCCCCCCCCEEEEEEEEECCCCCCCCC
TQDPIGAAATFRYEFTVPDPGTYFYHPHSGVQLDRGLYGVLLVDGPDEEDADQEWVVVLD
CCCCCCCEEEEEEEEECCCCCCEEECCCCCCEECCCEEEEEEEECCCCCCCCCCEEEEEE
DWVDGTGRTPDQVLESLRAGGGGGHGSMAGMDHGSMMGGGGGMQSRLLGGSGDVRYPLYL
ECCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCEECCCCCCHHEEECCCCCEEEEEEE
VNGRTADDPATLRGRPGQKVRIRVVNAGSDTAFRVAVGGHRLTVTHSDGFPVTPVSTDAL
ECCCCCCCCCCCCCCCCCEEEEEEEECCCCCEEEEEECCEEEEEEECCCCCCCCCCCCEE
LIGMGERFDVTVTLGDGVFALVAVAEGKNGGGLAVVRTGAGTTPGPDAWARHRGQPALLG
EEECCCCEEEEEEECCCEEEEEEEECCCCCCCEEEEEECCCCCCCCCHHHHHCCCCEEEE
ADLTPTESVRLPDRAVDRRHDLVLAGTMASYRWSINGRMFPDDEPLPVAEGERVRLRFVN
CCCCCCCCEECCHHHHCCCCCEEEEEEEEEEEEEECCEECCCCCCCCCCCCCEEEEEEEC
RSMMFHPMHVHGHTFALATGGARKDTVIVRPMEALEVDLDADNPGQWAAHCHNIYHAESG
CCEEEEEEEECCEEEEEEECCCCCCEEEEEEHHHEEEEECCCCCCHHHHHHHHEEECCCC
MMTTLSYRA
CEEEEEECC
>Mature Secondary Structure
MRGTAALGGATALAGLASCSRSGGTAVGPTAPAVTAAEDARRRAGGQLVTARLTPRPVTL
CCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCEECHHHHHHHCCCEEEEEEECCCEEEE
DLGGRAVDTWAYGDAVPGPLLRARAGDLLRVEVDNQLPVDTSVHWHGIALRNDMDGVPGV
ECCCEEEEEEECCCCCCCCHHHHCCCCEEEEEECCCCCCCCCEEEEEEEEECCCCCCCCC
TQDPIGAAATFRYEFTVPDPGTYFYHPHSGVQLDRGLYGVLLVDGPDEEDADQEWVVVLD
CCCCCCCEEEEEEEEECCCCCCEEECCCCCCEECCCEEEEEEEECCCCCCCCCCEEEEEE
DWVDGTGRTPDQVLESLRAGGGGGHGSMAGMDHGSMMGGGGGMQSRLLGGSGDVRYPLYL
ECCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCEECCCCCCHHEEECCCCCEEEEEEE
VNGRTADDPATLRGRPGQKVRIRVVNAGSDTAFRVAVGGHRLTVTHSDGFPVTPVSTDAL
ECCCCCCCCCCCCCCCCCEEEEEEEECCCCCEEEEEECCEEEEEEECCCCCCCCCCCCEE
LIGMGERFDVTVTLGDGVFALVAVAEGKNGGGLAVVRTGAGTTPGPDAWARHRGQPALLG
EEECCCCEEEEEEECCCEEEEEEEECCCCCCCEEEEEECCCCCCCCCHHHHHCCCCEEEE
ADLTPTESVRLPDRAVDRRHDLVLAGTMASYRWSINGRMFPDDEPLPVAEGERVRLRFVN
CCCCCCCCEECCHHHHCCCCCEEEEEEEEEEEEEECCEECCCCCCCCCCCCCEEEEEEEC
RSMMFHPMHVHGHTFALATGGARKDTVIVRPMEALEVDLDADNPGQWAAHCHNIYHAESG
CCEEEEEEEECCEEEEEEECCCCCCEEEEEEHHHEEEEECCCCCCHHHHHHHHEEECCCC
MMTTLSYRA
CEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12928499 [H]