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The map label for this gene is ywaC [H]

Identifier: 119714541

GI number: 119714541

Start: 296357

End: 297100

Strand: Reverse

Name: ywaC [H]

Synonym: Noca_0274

Alternate gene names: 119714541

Gene position: 297100-296357 (Counterclockwise)

Preceding gene: 119714542

Following gene: 119714536

Centisome position: 5.96

GC content: 69.35

Gene sequence:

>744_bases
GTGACCGAGGCGGGGAGCGGCCAGGGCGGCGAGGACCTCCGGCGGTTCATGCTCGAGCACCGGTTCGGCATGGACGAGAT
CGTCACGAAGCTGACCATCCTGCGCGACGAGTTCACGCACCTGCGCGACTACAACCCGATCGAGTCGGTGTCCTCGCGCC
TGAAGTCGCCCGAGAGCCTCGTGGAGAAGATGCTCCGCAAGGGCCTGGTCCTCGACGAGCGGCCGTCGTTCGACCAGATC
CGAGCGACGGTCACCGACATCGCCGGGGTCCGGGTCGTCTGCAGCTTCGTCTCCGACGTCTACCGGGTCTTCGACATGCT
CGTGGAGCAGGAGGACGTCTCGACGGTCGAGGTGCGCGACTACATCGCCACGCCCAAGCCCAACGGCTACCGCAGCCTGC
ACGCGCTGGTCGAGGTGCCGGTCTTCCTCTCGGAGGGGCCGGTTCCCGTGCTCGTCGAGGTGCAGTTCCGCACGATCGCG
ATGGACTTCTGGGCCAGCCTCGAGCACAAGATCTACTACAAGTACCGCCGCGAGGTCCCCGCCGAGCTGCTCGAGCGGCT
GCACGACGCCGCGGAGACGGCGTACGCCCTCGACGCGACGATGGAGCGCCTGCACGAGGAGGTACGCGGCCTCGACGAGC
TCCCACCGGACGTGCTCGCTCAGCTCCGCGACGGCGGAGAGCGGCCCGACGCCGCCCTGCGGGAGGCGCTGCGCAAGCTG
GGCGCCACCCCCGAGACGGCCTGA

Upstream 100 bases:

>100_bases
CCCGAGCCGCCAGGAACGTCCGTGGGATGCCCAGGACGGCACCGGTTCCGGCGGCCAGGGCCGTTGAACGGCGCCCGACG
CACGTCCGTACGCTGGACAC

Downstream 100 bases:

>100_bases
CGCCGGCTACCCGGCGAGCTCCAGCTCGGCGACCGTCTCGTAGCGCGGCCGCCCGCGCGGGCCCTCGCCGAGGTACGACG
CCACCAGCTCGACCCGGTCG

Product: RelA/SpoT domain-containing protein

Products: NA

Alternate protein names: (p)ppGpp synthase ywaC; Small alarmone synthase 2; SAS 2 [H]

Number of amino acids: Translated: 247; Mature: 246

Protein sequence:

>247_residues
MTEAGSGQGGEDLRRFMLEHRFGMDEIVTKLTILRDEFTHLRDYNPIESVSSRLKSPESLVEKMLRKGLVLDERPSFDQI
RATVTDIAGVRVVCSFVSDVYRVFDMLVEQEDVSTVEVRDYIATPKPNGYRSLHALVEVPVFLSEGPVPVLVEVQFRTIA
MDFWASLEHKIYYKYRREVPAELLERLHDAAETAYALDATMERLHEEVRGLDELPPDVLAQLRDGGERPDAALREALRKL
GATPETA

Sequences:

>Translated_247_residues
MTEAGSGQGGEDLRRFMLEHRFGMDEIVTKLTILRDEFTHLRDYNPIESVSSRLKSPESLVEKMLRKGLVLDERPSFDQI
RATVTDIAGVRVVCSFVSDVYRVFDMLVEQEDVSTVEVRDYIATPKPNGYRSLHALVEVPVFLSEGPVPVLVEVQFRTIA
MDFWASLEHKIYYKYRREVPAELLERLHDAAETAYALDATMERLHEEVRGLDELPPDVLAQLRDGGERPDAALREALRKL
GATPETA
>Mature_246_residues
TEAGSGQGGEDLRRFMLEHRFGMDEIVTKLTILRDEFTHLRDYNPIESVSSRLKSPESLVEKMLRKGLVLDERPSFDQIR
ATVTDIAGVRVVCSFVSDVYRVFDMLVEQEDVSTVEVRDYIATPKPNGYRSLHALVEVPVFLSEGPVPVLVEVQFRTIAM
DFWASLEHKIYYKYRREVPAELLERLHDAAETAYALDATMERLHEEVRGLDELPPDVLAQLRDGGERPDAALREALRKLG
ATPETA

Specific function: Functions as a (p)ppGpp synthase. In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. activities in respo

COG id: COG2357

COG function: function code S; Uncharacterized protein conserved in bacteria

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the relA/spoT family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007685 [H]

Pfam domain/function: PF04607 RelA_SpoT [H]

EC number: =2.7.6.5 [H]

Molecular weight: Translated: 28076; Mature: 27945

Theoretical pI: Translated: 4.69; Mature: 4.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEAGSGQGGEDLRRFMLEHRFGMDEIVTKLTILRDEFTHLRDYNPIESVSSRLKSPESL
CCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHH
VEKMLRKGLVLDERPSFDQIRATVTDIAGVRVVCSFVSDVYRVFDMLVEQEDVSTVEVRD
HHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
YIATPKPNGYRSLHALVEVPVFLSEGPVPVLVEVQFRTIAMDFWASLEHKIYYKYRREVP
HHCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCH
AELLERLHDAAETAYALDATMERLHEEVRGLDELPPDVLAQLRDGGERPDAALREALRKL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHCCCHHHHHHHHCCCCCCCHHHHHHHHHH
GATPETA
CCCCCCC
>Mature Secondary Structure 
TEAGSGQGGEDLRRFMLEHRFGMDEIVTKLTILRDEFTHLRDYNPIESVSSRLKSPESL
CCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHH
VEKMLRKGLVLDERPSFDQIRATVTDIAGVRVVCSFVSDVYRVFDMLVEQEDVSTVEVRD
HHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
YIATPKPNGYRSLHALVEVPVFLSEGPVPVLVEVQFRTIAMDFWASLEHKIYYKYRREVP
HHCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCH
AELLERLHDAAETAYALDATMERLHEEVRGLDELPPDVLAQLRDGGERPDAALREALRKL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHCCCHHHHHHHHCCCCCCCHHHHHHHHHH
GATPETA
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7934828; 9384377 [H]