Click here to switch to the map view.

The map label for this gene is cutS [H]

Identifier: 119714496

GI number: 119714496

Start: 245389

End: 245934

Strand: Direct

Name: cutS [H]

Synonym: Noca_0229

Alternate gene names: 119714496

Gene position: 245389-245934 (Clockwise)

Preceding gene: 119714495

Following gene: 119714497

Centisome position: 4.92

GC content: 70.15

Gene sequence:

>546_bases
ATGACGAGCTTGTTCGAAGAAGTTCCCGCGGCCGCGGCCGAAGGCGTCCCGGTCCGTCGGATCACCGTCCGCGTCAACGG
CACGCCGAGGACCGCCGACGTCGAGCCACGGCTGCTGCTCGCCCACCTGCTGCGCCAGGGCTTCAAGCTCACCGGCACCC
ACACCGGCTGCGACACCACGAACTGCGGCGCCTGCACCGTGCTGGTCGACGGGCTGCCGGTCAAGAGCTGCACGATGCTC
GCCGTCCAGGCGGACGGCCACGAGGTGACCACGGTCGAGGGACTGGCCGGACCGAGCGAGCTGCACCCGCTGCAGGAGGG
CTTCAAGGACGAGCACGGCCTGCAGTGCGGGTTCTGCACCCCGGGCATGATGCTCGCCGCCAAGGCGCTGCTCGCCGAGA
ACCCGGACCCGACCGAGGACGAGGTGCGGTTCGCGCTGTCCGGCAACCTGTGCCGCTGCACCGGCTACCAGAACATCGTG
AAGTCGGTGCTGTGGGCGGCCAAGCAGATGAACGGCGCCTCGGCTGACGAGGGGAGCGCGGAGTGA

Upstream 100 bases:

>100_bases
CCTCCGACCACCGTGGCAGCGCGTCGTACAAGCGGCACGTGATCCACACCTTCGTCACCCGGATCCTGACCCGGGTCACC
CAGACCAGCGAGGCTGCAGC

Downstream 100 bases:

>100_bases
CCGCCACCGAGCCCGCACCGACCACCAGCCGGGCGCTGGACGAGATCAAGATCGGCGGGATGGGCGCGAGCCGCAGGCGC
GTCGAGGACAACCGCTTCAT

Product: 2Fe-2S iron-sulfur cluster binding domain-containing protein

Products: NA

Alternate protein names: CO dehydrogenase subunit S; CO-DH S [H]

Number of amino acids: Translated: 181; Mature: 180

Protein sequence:

>181_residues
MTSLFEEVPAAAAEGVPVRRITVRVNGTPRTADVEPRLLLAHLLRQGFKLTGTHTGCDTTNCGACTVLVDGLPVKSCTML
AVQADGHEVTTVEGLAGPSELHPLQEGFKDEHGLQCGFCTPGMMLAAKALLAENPDPTEDEVRFALSGNLCRCTGYQNIV
KSVLWAAKQMNGASADEGSAE

Sequences:

>Translated_181_residues
MTSLFEEVPAAAAEGVPVRRITVRVNGTPRTADVEPRLLLAHLLRQGFKLTGTHTGCDTTNCGACTVLVDGLPVKSCTML
AVQADGHEVTTVEGLAGPSELHPLQEGFKDEHGLQCGFCTPGMMLAAKALLAENPDPTEDEVRFALSGNLCRCTGYQNIV
KSVLWAAKQMNGASADEGSAE
>Mature_180_residues
TSLFEEVPAAAAEGVPVRRITVRVNGTPRTADVEPRLLLAHLLRQGFKLTGTHTGCDTTNCGACTVLVDGLPVKSCTMLA
VQADGHEVTTVEGLAGPSELHPLQEGFKDEHGLQCGFCTPGMMLAAKALLAENPDPTEDEVRFALSGNLCRCTGYQNIVK
SVLWAAKQMNGASADEGSAE

Specific function: Catalyzes the oxidation of carbon monoxide to carbon dioxide [H]

COG id: COG2080

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI71773480, Length=91, Percent_Identity=46.1538461538462, Blast_Score=92, Evalue=2e-19,
Organism=Homo sapiens, GI91823271, Length=154, Percent_Identity=37.6623376623377, Blast_Score=87, Evalue=8e-18,
Organism=Escherichia coli, GI1786480, Length=186, Percent_Identity=40.3225806451613, Blast_Score=135, Evalue=2e-33,
Organism=Escherichia coli, GI1789232, Length=147, Percent_Identity=45.578231292517, Blast_Score=118, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI17540638, Length=140, Percent_Identity=45, Blast_Score=132, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI17539860, Length=159, Percent_Identity=37.1069182389937, Blast_Score=114, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI32566215, Length=168, Percent_Identity=34.5238095238095, Blast_Score=112, Evalue=1e-25,
Organism=Drosophila melanogaster, GI17737937, Length=149, Percent_Identity=40.2684563758389, Blast_Score=102, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24647201, Length=151, Percent_Identity=34.4370860927152, Blast_Score=84, Evalue=6e-17,
Organism=Drosophila melanogaster, GI24647199, Length=148, Percent_Identity=33.7837837837838, Blast_Score=82, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24647195, Length=158, Percent_Identity=33.5443037974684, Blast_Score=80, Evalue=7e-16,
Organism=Drosophila melanogaster, GI24647197, Length=158, Percent_Identity=33.5443037974684, Blast_Score=80, Evalue=7e-16,
Organism=Drosophila melanogaster, GI24647193, Length=159, Percent_Identity=32.7044025157233, Blast_Score=75, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002888
- InterPro:   IPR012675
- InterPro:   IPR001041 [H]

Pfam domain/function: PF00111 Fer2; PF01799 Fer2_2 [H]

EC number: =1.2.99.2 [H]

Molecular weight: Translated: 19094; Mature: 18963

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
7.2 %Cys+Met (Translated Protein)
4.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
6.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSLFEEVPAAAAEGVPVRRITVRVNGTPRTADVEPRLLLAHLLRQGFKLTGTHTGCDTT
CCCHHHHHCHHHHCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHCCCEECCCCCCCCCC
NCGACTVLVDGLPVKSCTMLAVQADGHEVTTVEGLAGPSELHPLQEGFKDEHGLQCGFCT
CCCEEEEEECCCCCCCEEEEEEECCCCEEEEECCCCCCHHHHHHHHCCCCCCCCEECCCC
PGMMLAAKALLAENPDPTEDEVRFALSGNLCRCTGYQNIVKSVLWAAKQMNGASADEGSA
CHHHHHHHHHHHCCCCCCHHHEEEEECCCEEEECCHHHHHHHHHHHHHHCCCCCCCCCCC
E
C
>Mature Secondary Structure 
TSLFEEVPAAAAEGVPVRRITVRVNGTPRTADVEPRLLLAHLLRQGFKLTGTHTGCDTT
CCHHHHHCHHHHCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHCCCEECCCCCCCCCC
NCGACTVLVDGLPVKSCTMLAVQADGHEVTTVEGLAGPSELHPLQEGFKDEHGLQCGFCT
CCCEEEEEECCCCCCCEEEEEEECCCCEEEEECCCCCCHHHHHHHHCCCCCCCCEECCCC
PGMMLAAKALLAENPDPTEDEVRFALSGNLCRCTGYQNIVKSVLWAAKQMNGASADEGSA
CHHHHHHHHHHHCCCCCCHHHEEEEECCCEEEECCHHHHHHHHHHHHHHCCCCCCCCCCC
E
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10482497; 2818128; 10966817; 11076018 [H]