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The map label for this gene is pckG [H]

Identifier: 119714457

GI number: 119714457

Start: 200387

End: 202231

Strand: Reverse

Name: pckG [H]

Synonym: Noca_0190

Alternate gene names: 119714457

Gene position: 202231-200387 (Counterclockwise)

Preceding gene: 119714458

Following gene: 119714456

Centisome position: 4.06

GC content: 69.27

Gene sequence:

>1845_bases
ATGACCGCCGACACACAGGCTCCGATCAGCACGCCCACGTCCGACCTGTCGGGTCGGCCGAGCACCCATCCGGGCATCCT
CGAGTTCGTCTCCGAGGTCGCCGCCCTGACCCAACCGGACCGGATCCACTGGTGCACCGGCTCGGACGAGGAGTGGACCG
TCCTCACCGACGCCCTGGTGTCGACCGGGACCTTCACCCCCCTGAACCCGGATCTCAAGCCGAACTCCTTCCACGCCGCC
TCCGACCCGATGGACGTCGCGCGCGTCGAGGGCCGCACCTTCATCTGCTCGGTCGACGAGCGGGACGCGGGGCCCACCAA
CAACTGGATGGACCCGCAGGAGATGAAGGCGATCATGCGCGACCTCTACGCCGGCTGCATGCGCGGCCGGACGATGTACG
TGATCCCGTTCGTCATGGGCCACCTGGACGCCGAGCAGCCGATGTTCGGCATCGAGATCACCGACTCCGCCTACGTCACC
GCCTCGATGCGGGTGATGGCCCGGATGGGCAGCAACGTGCTGGAGCGGATGGAGGAGCTCGAGGCCGAGTTCGTGCCGGC
GCTGCACTCGGTCGGCCACCCGCTCGAGCCGGGCGAGGCGGACGTCGTGTGGCCGTGCAACGACACCAAGTACATCGTGC
AGTTCCCCGAGGAGCATGCGATCTGGTCCTACGGCTCCGGCTACGGCGGCAACGCGCTGCTGGGCAAGAAGTGCTATGCG
CTGCGCATCGCGAGCGTGATGGCCCGCGACGAGGGCTGGCTCGCCGAGCACATGCTGATCCTCAAGCTCACCTCGCCGCA
GGGCGTCGTGAAGTACGTCGCCGCCGCGTTCCCGAGCGCCTGCGGCAAGACGAACCTCGCGATGCTCCGGCCGACGATCC
CCGGCTGGAAGGTCGAGACCCTCGGCGACGACATCGCCTGGATGCGCGTCGGCGAGGACGGCCGGTTGTGGGCGGTCAAC
CCGGAGTATGGCTTCTTCGGGGTCGCGCCCGGCACCAACGAGCACACCAACCCCAACGCGATGACGACCATCAACAAGGG
CAACTCGGTGTTCACCAACGTCGCGCTGACCGAGGACGGCGACGTCTGGTGGGAGGGTCTGGAGAACCCGCCGGCCCGCG
CCACGTCCTGGACGGGCCAGCCCTGGACCCCGGAGTCCGAGGAGCCGTCCAGCCACCCCAACAGCCGCTACTGCACCCCG
ATCAAGCAGTGCGACATCCTCGCCGCGGAGTACGACGACCCGCGCGGCGTACCGATCGACGCGATCCTGTTCGGTGGGCG
CCGCGAGACCACCGTGCCGCTGGTCTTCGAGGCCCGGGACTGGACGCACGGGACCTTCCTCGGCGCCACGCTCTCCTCCG
AGACGACGGCGGCGGCCGTCGGCGCGGTGGGCGTGGTGCGCCGCGACCCGATGGCGATGCTGCCGTTCATCGGCTACAAC
GCCGGCGACTACTTCAACCACTGGATCACGGTCGGGAAGGACAACGACGAGGCCTTGCTCCCGCGGATCTTCTACGTGAA
CTGGTTCCGTCGCGACGCTGACGGCGGCTTCCTATGGCCGGGCTTCGGCGAGAACAGCCGGGTCCTGAAGTGGGTCGTCG
AGCGGATCGACGGCCAGGCGGCCGCCGTGGAGACCCCGATCGGCTACGTCCCGACGCCGGAGTCCCTCGACACCGATGGC
CTCGACCTCTCAGCCGAGGACCTGGCCGCGGCGCTCGCCGTCGACCCGGAGGAGTGGAGGGCGGAGGTCCCGCAGATCCA
GGAGTGGTTCGAGAAGTTCGGCGAGGACCTCCCGGCCGTGCTCTGGACCGAGCTGGACGGCCTGCGCGCTCGCCTCGGCT
CCTGA

Upstream 100 bases:

>100_bases
CGATCCAAGACCGACTCCACGACAGCCCGTCGACCGTGTCGACGGCCGGAGGCCCCGAGAGCCGGATGGCCACCGCGAAT
CCGCGAGAGGGAACCAGGCA

Downstream 100 bases:

>100_bases
CACCGGCCGCCCGTCGCCCGGATCACCACGGAAGGACCCCGTCCCGGCAGGGACGGGGTCCTCCCCGTTGCGGCACTGTG
GGATCATCGGCTCACGGGTT

Product: phosphoenolpyruvate carboxykinase

Products: NA

Alternate protein names: PEP carboxykinase; PEPCK; Phosphoenolpyruvate carboxylase [H]

Number of amino acids: Translated: 614; Mature: 613

Protein sequence:

>614_residues
MTADTQAPISTPTSDLSGRPSTHPGILEFVSEVAALTQPDRIHWCTGSDEEWTVLTDALVSTGTFTPLNPDLKPNSFHAA
SDPMDVARVEGRTFICSVDERDAGPTNNWMDPQEMKAIMRDLYAGCMRGRTMYVIPFVMGHLDAEQPMFGIEITDSAYVT
ASMRVMARMGSNVLERMEELEAEFVPALHSVGHPLEPGEADVVWPCNDTKYIVQFPEEHAIWSYGSGYGGNALLGKKCYA
LRIASVMARDEGWLAEHMLILKLTSPQGVVKYVAAAFPSACGKTNLAMLRPTIPGWKVETLGDDIAWMRVGEDGRLWAVN
PEYGFFGVAPGTNEHTNPNAMTTINKGNSVFTNVALTEDGDVWWEGLENPPARATSWTGQPWTPESEEPSSHPNSRYCTP
IKQCDILAAEYDDPRGVPIDAILFGGRRETTVPLVFEARDWTHGTFLGATLSSETTAAAVGAVGVVRRDPMAMLPFIGYN
AGDYFNHWITVGKDNDEALLPRIFYVNWFRRDADGGFLWPGFGENSRVLKWVVERIDGQAAAVETPIGYVPTPESLDTDG
LDLSAEDLAAALAVDPEEWRAEVPQIQEWFEKFGEDLPAVLWTELDGLRARLGS

Sequences:

>Translated_614_residues
MTADTQAPISTPTSDLSGRPSTHPGILEFVSEVAALTQPDRIHWCTGSDEEWTVLTDALVSTGTFTPLNPDLKPNSFHAA
SDPMDVARVEGRTFICSVDERDAGPTNNWMDPQEMKAIMRDLYAGCMRGRTMYVIPFVMGHLDAEQPMFGIEITDSAYVT
ASMRVMARMGSNVLERMEELEAEFVPALHSVGHPLEPGEADVVWPCNDTKYIVQFPEEHAIWSYGSGYGGNALLGKKCYA
LRIASVMARDEGWLAEHMLILKLTSPQGVVKYVAAAFPSACGKTNLAMLRPTIPGWKVETLGDDIAWMRVGEDGRLWAVN
PEYGFFGVAPGTNEHTNPNAMTTINKGNSVFTNVALTEDGDVWWEGLENPPARATSWTGQPWTPESEEPSSHPNSRYCTP
IKQCDILAAEYDDPRGVPIDAILFGGRRETTVPLVFEARDWTHGTFLGATLSSETTAAAVGAVGVVRRDPMAMLPFIGYN
AGDYFNHWITVGKDNDEALLPRIFYVNWFRRDADGGFLWPGFGENSRVLKWVVERIDGQAAAVETPIGYVPTPESLDTDG
LDLSAEDLAAALAVDPEEWRAEVPQIQEWFEKFGEDLPAVLWTELDGLRARLGS
>Mature_613_residues
TADTQAPISTPTSDLSGRPSTHPGILEFVSEVAALTQPDRIHWCTGSDEEWTVLTDALVSTGTFTPLNPDLKPNSFHAAS
DPMDVARVEGRTFICSVDERDAGPTNNWMDPQEMKAIMRDLYAGCMRGRTMYVIPFVMGHLDAEQPMFGIEITDSAYVTA
SMRVMARMGSNVLERMEELEAEFVPALHSVGHPLEPGEADVVWPCNDTKYIVQFPEEHAIWSYGSGYGGNALLGKKCYAL
RIASVMARDEGWLAEHMLILKLTSPQGVVKYVAAAFPSACGKTNLAMLRPTIPGWKVETLGDDIAWMRVGEDGRLWAVNP
EYGFFGVAPGTNEHTNPNAMTTINKGNSVFTNVALTEDGDVWWEGLENPPARATSWTGQPWTPESEEPSSHPNSRYCTPI
KQCDILAAEYDDPRGVPIDAILFGGRRETTVPLVFEARDWTHGTFLGATLSSETTAAAVGAVGVVRRDPMAMLPFIGYNA
GDYFNHWITVGKDNDEALLPRIFYVNWFRRDADGGFLWPGFGENSRVLKWVVERIDGQAAAVETPIGYVPTPESLDTDGL
DLSAEDLAAALAVDPEEWRAEVPQIQEWFEKFGEDLPAVLWTELDGLRARLGS

Specific function: Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle [H]

COG id: COG1274

COG function: function code C; Phosphoenolpyruvate carboxykinase (GTP)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family [H]

Homologues:

Organism=Homo sapiens, GI66346721, Length=615, Percent_Identity=50.8943089430894, Blast_Score=602, Evalue=1e-172,
Organism=Homo sapiens, GI187281517, Length=602, Percent_Identity=50.1661129568106, Blast_Score=591, Evalue=1e-169,
Organism=Homo sapiens, GI66346723, Length=386, Percent_Identity=52.5906735751295, Blast_Score=382, Evalue=1e-106,
Organism=Caenorhabditis elegans, GI17555492, Length=621, Percent_Identity=47.0209339774557, Blast_Score=543, Evalue=1e-155,
Organism=Caenorhabditis elegans, GI71989645, Length=606, Percent_Identity=46.039603960396, Blast_Score=540, Evalue=1e-154,
Organism=Caenorhabditis elegans, GI71989658, Length=606, Percent_Identity=46.039603960396, Blast_Score=540, Evalue=1e-153,
Organism=Caenorhabditis elegans, GI71989653, Length=594, Percent_Identity=46.2962962962963, Blast_Score=531, Evalue=1e-151,
Organism=Caenorhabditis elegans, GI32564411, Length=556, Percent_Identity=48.3812949640288, Blast_Score=516, Evalue=1e-146,
Organism=Caenorhabditis elegans, GI32564407, Length=525, Percent_Identity=49.7142857142857, Blast_Score=496, Evalue=1e-140,
Organism=Caenorhabditis elegans, GI71989649, Length=490, Percent_Identity=47.3469387755102, Blast_Score=453, Evalue=1e-127,
Organism=Caenorhabditis elegans, GI32564409, Length=369, Percent_Identity=49.3224932249323, Blast_Score=347, Evalue=1e-95,
Organism=Caenorhabditis elegans, GI17540956, Length=644, Percent_Identity=24.223602484472, Blast_Score=145, Evalue=4e-35,
Organism=Drosophila melanogaster, GI24655085, Length=602, Percent_Identity=51.328903654485, Blast_Score=619, Evalue=1e-177,
Organism=Drosophila melanogaster, GI24655082, Length=604, Percent_Identity=50, Blast_Score=592, Evalue=1e-169,
Organism=Drosophila melanogaster, GI161077226, Length=569, Percent_Identity=51.1423550087873, Blast_Score=564, Evalue=1e-161,
Organism=Drosophila melanogaster, GI24655088, Length=503, Percent_Identity=53.2803180914513, Blast_Score=551, Evalue=1e-157,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018091
- InterPro:   IPR013035
- InterPro:   IPR008209
- InterPro:   IPR008210 [H]

Pfam domain/function: PF00821 PEPCK [H]

EC number: =4.1.1.32 [H]

Molecular weight: Translated: 67601; Mature: 67469

Theoretical pI: Translated: 4.30; Mature: 4.30

Prosite motif: PS00505 PEPCK_GTP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTADTQAPISTPTSDLSGRPSTHPGILEFVSEVAALTQPDRIHWCTGSDEEWTVLTDALV
CCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCEEEEEHHHH
STGTFTPLNPDLKPNSFHAASDPMDVARVEGRTFICSVDERDAGPTNNWMDPQEMKAIMR
HCCCCCCCCCCCCCCCCCCCCCCCHHHEECCCEEEEECCCCCCCCCCCCCCHHHHHHHHH
DLYAGCMRGRTMYVIPFVMGHLDAEQPMFGIEITDSAYVTASMRVMARMGSNVLERMEEL
HHHHHHHCCCEEEEEEHHHHCCCCCCCEEEEEECCCEEEHHHHHHHHHHHHHHHHHHHHH
EAEFVPALHSVGHPLEPGEADVVWPCNDTKYIVQFPEEHAIWSYGSGYGGNALLGKKCYA
HHHHHHHHHHCCCCCCCCCCCEEECCCCCEEEEECCCCCCEEECCCCCCCCCCCCCHHHH
LRIASVMARDEGWLAEHMLILKLTSPQGVVKYVAAAFPSACGKTNLAMLRPTIPGWKVET
HHHHHHHHCCCCCCEEEEEEEEECCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCCEEEE
LGDDIAWMRVGEDGRLWAVNPEYGFFGVAPGTNEHTNPNAMTTINKGNSVFTNVALTEDG
CCCCEEEEEECCCCCEEEECCCCCEEECCCCCCCCCCCCEEEEEECCCEEEEEEEEECCC
DVWWEGLENPPARATSWTGQPWTPESEEPSSHPNSRYCTPIKQCDILAAEYDDPRGVPID
CHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCEEEECCCCCCCCEEE
AILFGGRRETTVPLVFEARDWTHGTFLGATLSSETTAAAVGAVGVVRRDPMAMLPFIGYN
EEEECCCCCCEEEEEEECCCCCCCEEEEEECCCCCHHHHHHHHHHHCCCCHHCCCCCCCC
AGDYFNHWITVGKDNDEALLPRIFYVNWFRRDADGGFLWPGFGENSRVLKWVVERIDGQA
CCCCCCCEEEECCCCCCHHCCEEEEEEEEEECCCCCEECCCCCCCHHHHHHHHHHHCCCE
AAVETPIGYVPTPESLDTDGLDLSAEDLAAALAVDPEEWRAEVPQIQEWFEKFGEDLPAV
EEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCHHHHHCCCHHHHHHHHHHCCCCCHH
LWTELDGLRARLGS
HHHHHHHHHHHCCC
>Mature Secondary Structure 
TADTQAPISTPTSDLSGRPSTHPGILEFVSEVAALTQPDRIHWCTGSDEEWTVLTDALV
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCEEEEEHHHH
STGTFTPLNPDLKPNSFHAASDPMDVARVEGRTFICSVDERDAGPTNNWMDPQEMKAIMR
HCCCCCCCCCCCCCCCCCCCCCCCHHHEECCCEEEEECCCCCCCCCCCCCCHHHHHHHHH
DLYAGCMRGRTMYVIPFVMGHLDAEQPMFGIEITDSAYVTASMRVMARMGSNVLERMEEL
HHHHHHHCCCEEEEEEHHHHCCCCCCCEEEEEECCCEEEHHHHHHHHHHHHHHHHHHHHH
EAEFVPALHSVGHPLEPGEADVVWPCNDTKYIVQFPEEHAIWSYGSGYGGNALLGKKCYA
HHHHHHHHHHCCCCCCCCCCCEEECCCCCEEEEECCCCCCEEECCCCCCCCCCCCCHHHH
LRIASVMARDEGWLAEHMLILKLTSPQGVVKYVAAAFPSACGKTNLAMLRPTIPGWKVET
HHHHHHHHCCCCCCEEEEEEEEECCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCCEEEE
LGDDIAWMRVGEDGRLWAVNPEYGFFGVAPGTNEHTNPNAMTTINKGNSVFTNVALTEDG
CCCCEEEEEECCCCCEEEECCCCCEEECCCCCCCCCCCCEEEEEECCCEEEEEEEEECCC
DVWWEGLENPPARATSWTGQPWTPESEEPSSHPNSRYCTPIKQCDILAAEYDDPRGVPID
CHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCEEEECCCCCCCCEEE
AILFGGRRETTVPLVFEARDWTHGTFLGATLSSETTAAAVGAVGVVRRDPMAMLPFIGYN
EEEECCCCCCEEEEEEECCCCCCCEEEEEECCCCCHHHHHHHHHHHCCCCHHCCCCCCCC
AGDYFNHWITVGKDNDEALLPRIFYVNWFRRDADGGFLWPGFGENSRVLKWVVERIDGQA
CCCCCCCEEEECCCCCCHHCCEEEEEEEEEECCCCCEECCCCCCCHHHHHHHHHHHCCCE
AAVETPIGYVPTPESLDTDGLDLSAEDLAAALAVDPEEWRAEVPQIQEWFEKFGEDLPAV
EEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCHHHHHCCCHHHHHHHHHHCCCCCHH
LWTELDGLRARLGS
HHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA