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The map label for this gene is pheA [H]

Identifier: 119714437

GI number: 119714437

Start: 183811

End: 184674

Strand: Reverse

Name: pheA [H]

Synonym: Noca_0170

Alternate gene names: 119714437

Gene position: 184674-183811 (Counterclockwise)

Preceding gene: 119714440

Following gene: 119714436

Centisome position: 3.7

GC content: 70.25

Gene sequence:

>864_bases
GTGACCCGACGCATCGCCTACCAGGGGGAGCCCGGCTCCAACTCCCACCAGGTCTGCAAGCAGCACTACCCCGACTGGGA
GGCGGTGCCCTGCGCGTCGTTCGAGGACGTCTTCGCGGCCGTCGAGGGCGGTCCGGGAGTGGCGCCGGCCGCGGACCTCG
CGATGATCCCGATCGACAACTCGATCGCCGGCCGGGTCGCCGACATCCATCACTTCCTTCCCGGCTCGCGGCTGCACATC
ATCGCCGAGCACTTCCTGCGGATCCGCTTCCACCTGCTCGGGGTGCCCGGCTCCTCGCTGGACACGATCACGACCGTGCA
CAGCCACGTGCACGCCCTCGGCCAGTGCCGCAAGGTGATCCGCGAGCACGGCCTGAAGCCGGTGATCGCGGGCGACACCG
CCGGCGCGGCGCGCGAGGTCGCCGAGCTGGGCGACCCGACGCTGGCGGCGATCTCCCCGCCGCTGGCCGCGGAGATCTAC
GGCCTGGATGTGCTGGAGGAGGACGTCGAGGACGAGGAGCACAACACCACCCGGTTCGTCGTGCTCTCCCCCGACCTGGT
GCAGGCGCCGTCGGGCAACGGCCCGGTGGTCACCAGCTTCATCTTCAACGTCCGCAACCTCCCGGCGGCGCTCTACAAGG
CCCTCGGCGGGTTCGCGACCAACGGGGTGAACATGACCAAGCTGGAGAGCTACATGGTCGGCGGGGAGTTCGCCGCGACC
CAGTTCCTCGCCGAGGTCGACGGGCACCCCGACGACATCGGGGTGAAGCGCGCCCTGGAGGAGCTGGCGTTCTTCACCAC
CGACATCAAGGTCCTCGGCGTCTACCCCGCCGACCCCTTCCGCGCCGAGGTGTCCTCGCCCTGA

Upstream 100 bases:

>100_bases
ATGACGGGGCTCCGGACCCGGCCTGGCGTGCCGCGCGGGCGGATCCGACCGGCGGACGCCCGGGCCGGGCAGCCGGTCAC
TGCGTGGGACGATGAGCACC

Downstream 100 bases:

>100_bases
GCCCGACGCTCCTCCCTGGTCGGGCAACTCCTGCGCTCATCGGGTGGGGTGCCCGGCCAACCGTTCCGGTTTCCCCGGTT
AACCGGGGATGTTGGAACTG

Product: prephenate dehydratase

Products: NA

Alternate protein names: Chorismate mutase; CM; Prephenate dehydratase; PDT [H]

Number of amino acids: Translated: 287; Mature: 286

Protein sequence:

>287_residues
MTRRIAYQGEPGSNSHQVCKQHYPDWEAVPCASFEDVFAAVEGGPGVAPAADLAMIPIDNSIAGRVADIHHFLPGSRLHI
IAEHFLRIRFHLLGVPGSSLDTITTVHSHVHALGQCRKVIREHGLKPVIAGDTAGAAREVAELGDPTLAAISPPLAAEIY
GLDVLEEDVEDEEHNTTRFVVLSPDLVQAPSGNGPVVTSFIFNVRNLPAALYKALGGFATNGVNMTKLESYMVGGEFAAT
QFLAEVDGHPDDIGVKRALEELAFFTTDIKVLGVYPADPFRAEVSSP

Sequences:

>Translated_287_residues
MTRRIAYQGEPGSNSHQVCKQHYPDWEAVPCASFEDVFAAVEGGPGVAPAADLAMIPIDNSIAGRVADIHHFLPGSRLHI
IAEHFLRIRFHLLGVPGSSLDTITTVHSHVHALGQCRKVIREHGLKPVIAGDTAGAAREVAELGDPTLAAISPPLAAEIY
GLDVLEEDVEDEEHNTTRFVVLSPDLVQAPSGNGPVVTSFIFNVRNLPAALYKALGGFATNGVNMTKLESYMVGGEFAAT
QFLAEVDGHPDDIGVKRALEELAFFTTDIKVLGVYPADPFRAEVSSP
>Mature_286_residues
TRRIAYQGEPGSNSHQVCKQHYPDWEAVPCASFEDVFAAVEGGPGVAPAADLAMIPIDNSIAGRVADIHHFLPGSRLHII
AEHFLRIRFHLLGVPGSSLDTITTVHSHVHALGQCRKVIREHGLKPVIAGDTAGAAREVAELGDPTLAAISPPLAAEIYG
LDVLEEDVEDEEHNTTRFVVLSPDLVQAPSGNGPVVTSFIFNVRNLPAALYKALGGFATNGVNMTKLESYMVGGEFAATQ
FLAEVDGHPDDIGVKRALEELAFFTTDIKVLGVYPADPFRAEVSSP

Specific function: L-phenylalanine biosynthesis. [C]

COG id: COG0077

COG function: function code E; Prephenate dehydratase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 prephenate dehydratase domain [H]

Homologues:

Organism=Escherichia coli, GI1788951, Length=280, Percent_Identity=32.1428571428571, Blast_Score=134, Evalue=6e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008242
- InterPro:   IPR002701
- InterPro:   IPR020822
- InterPro:   IPR010952
- InterPro:   IPR001086
- InterPro:   IPR018528 [H]

Pfam domain/function: PF01817 CM_2; PF00800 PDT [H]

EC number: =5.4.99.5; =4.2.1.51 [H]

Molecular weight: Translated: 30719; Mature: 30588

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: PS00857 PREPHENATE_DEHYDR_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRRIAYQGEPGSNSHQVCKQHYPDWEAVPCASFEDVFAAVEGGPGVAPAADLAMIPIDN
CCCEEEECCCCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCEEEEECCC
SIAGRVADIHHFLPGSRLHIIAEHFLRIRFHLLGVPGSSLDTITTVHSHVHALGQCRKVI
CHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHHHHHHH
REHGLKPVIAGDTAGAAREVAELGDPTLAAISPPLAAEIYGLDVLEEDVEDEEHNTTRFV
HHCCCCEEEECCCCHHHHHHHHCCCCCEECCCCCHHHHHHHHHHHHHHCCCCCCCCEEEE
VLSPDLVQAPSGNGPVVTSFIFNVRNLPAALYKALGGFATNGVNMTKLESYMVGGEFAAT
EECCCCEECCCCCCCCHHHHHHHHHCCHHHHHHHHCCHHCCCCCHHHHHHHHCCCHHHHH
QFLAEVDGHPDDIGVKRALEELAFFTTDIKVLGVYPADPFRAEVSSP
HHHHHHCCCCCHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCC
>Mature Secondary Structure 
TRRIAYQGEPGSNSHQVCKQHYPDWEAVPCASFEDVFAAVEGGPGVAPAADLAMIPIDN
CCEEEECCCCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCEEEEECCC
SIAGRVADIHHFLPGSRLHIIAEHFLRIRFHLLGVPGSSLDTITTVHSHVHALGQCRKVI
CHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHHHHHHH
REHGLKPVIAGDTAGAAREVAELGDPTLAAISPPLAAEIYGLDVLEEDVEDEEHNTTRFV
HHCCCCEEEECCCCHHHHHHHHCCCCCEECCCCCHHHHHHHHHHHHHHCCCCCCCCEEEE
VLSPDLVQAPSGNGPVVTSFIFNVRNLPAALYKALGGFATNGVNMTKLESYMVGGEFAAT
EECCCCEECCCCCCCCHHHHHHHHHCCHHHHHHHHCCHHCCCCCHHHHHHHHCCCHHHHH
QFLAEVDGHPDDIGVKRALEELAFFTTDIKVLGVYPADPFRAEVSSP
HHHHHHCCCCCHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]