Click here to switch to the map view.

The map label for this gene is accA1 [H]

Identifier: 119714415

GI number: 119714415

Start: 163348

End: 165252

Strand: Direct

Name: accA1 [H]

Synonym: Noca_0148

Alternate gene names: 119714415

Gene position: 163348-165252 (Clockwise)

Preceding gene: 119714414

Following gene: 119714416

Centisome position: 3.28

GC content: 72.76

Gene sequence:

>1905_bases
ATGACGAATTCCCTCGCAGCAGTCCTGGAGTCCGTGCTCGTCGCCAACCGCGGCGAGATCGCGCTGCGCGTCATGCGCGC
CTGCCGGAAGTACGGCGTGCGGACGATCGCGATCTACACCGACCTCGACGTCGACGCGCCGCACGTCCGGGCCGCGGACG
ATGCCGTGCACGTCTCGAGCTACCTGGACATCGACGCGGTCGTCGCCGCCGCCGTTGCGAGCGGGGCCACCGCGGTGCAC
CCCGGCTACGGCTTCCTCTCGGAACGGTCCGCGTTCGTTCGTGCGGTCGAGGCCGCCGGTGTCGTCTTCGTCGGACCGCC
CGCCGACGTCATGGACAAGATGGGCCGCAAGGACGCCGCCCGCGAGATCGCGGTCGCGGCCGGCGTGCCGGTCGTGCCGC
GGGGCGAGGACGCGGGCTTTCCCGTCCTGGTGAAGGCCGCCGCCGGAGGCGGCGGCAAGGGCATGCGCGTCGTTCGTGAG
GAGGCCGACCTCGAGGAGGCCAAGGCCGCCGCGGCCCGCGAGGCGCTCGCCGCGTTCGGCGACGACACCCTCCTGATCGA
GAAGTACGTCGAGCGCGGCCGGCACATCGAGGTCCAGATCATGGCCGACGCGCACGGCCACGTGGTCCACCTCGACGAGC
GGGACTGCTCCACCCAGCGCCGGCACCAGAAGGTGCTCGAGGAGGCGCCCGCGCCGACCATCAGCCCCGAGGTCCGCGAG
CTGGTCACCAGCAGCGCCGTGGCTCTGGCCAAGCAGGTGGGCTACGTGAACGCCGGCACCGTCGAGTTCCTCGTCGACGA
CGACACGGGTGAGGCGTACTTCCTGGAGATGAACACCCGGCTCCAGGTCGAGCACCCCGTCACCGAGCTGATCCACCACG
ACCTGGACCTCGTCCTCCACCAGCTCCTCGTCGCGCTCGGGCACCCCCTGGAGATCGAGCAGGACAACGTCCGGCCGTCC
GGGCACGCGATCGAGGCGCGGGTGTACGCCGAGGACTCCTTCGGCGGCTTCCTGCCCCAGGCCGGGCGCACGTCGATCGT
GCGCTGGCCGGCCGGGGTCCGCGTGGACCACGCGCTCGAGCCCGACCAGGTCGTCAGCACGTCGTACGACCCGATGCTTG
GCAAGGTCATCGTGCACGGCCCCGACCGAGAGTCCGCGCGCCGCGCCCTGGTCGACGCGCTGGACCGGACCGCGATCCTC
GGGCTCACGACCAACGTCGGGTTCCTGCGCGCGCTGGTGGCGAGCGAGGAGTTCCGCGACGCCGCCATCGACACCGCCTG
GCTGGACCGCAACAGCGTCCCGGCGCCCGACGACGACCTGCCGCGGGTCTTCGTCGCCTGGGTGAGCGCGATGCTTGCCG
CCGGGCACGACAGCGGGCAGCCGTTCCGGGCCGATGGCTGGCGCTCCGGCGCCGACCCCGCGCCGACCATCGTCGAGCTC
GACCGGCCGGTCGTGGTCGACCGGTTCGCGGGCCTGGTCGACGGCCGTGCGGTGCGGCAGGTCGCGGCCGCCGATCACGT
CCTCACCCTCGAGGTCGACGGGCGCGTGCACTCGGCGGTCGTCAACGTGCAGCCACACGTCGCCGAGGTCGTCCACCACG
GCCAGCGCTTCGTGTTCGAGCGGCCCGACGTGTTCGGTGACCACGCGGTCGACGTCGGCGACGGGGCGATCGCCGCACCG
ATGCCGGGTACCGTCTTGGACGTCCGCGTCGAGCCCGGCGCGACCGTCGTCGCCGGCGACGTGCTCGGCGTCCTGGAGGC
GATGAAGATGGAGCTGACCCTCAAGGCGCCCTTCGACGGCACGGTCAGCCAGGTCGGGGCCACCATCGGCGCCCAGGTCG
CGCTCGGCGCCCGGCTGTTCGTGGTCGAGCCGCACGCCGAGGCCGAGGAAGAGGAGGCCGGCTGA

Upstream 100 bases:

>100_bases
TTCCGGATGTGATCTCACCCCACGACGTTCTTCGCTCCCCCGCTCCGCTCCTCCGTGAACAACGCCGCGGGGACCCCGAC
ACCTCGGAGAAACCAGTCCT

Downstream 100 bases:

>100_bases
TGCGCACCCCTGCCGTCGTACCCGCCCTCCCGGTGTCGGCCGCGCCGATGCCGGACCGCGTCACGATCTACGAGGTCGGC
CCCCGCGACGGTCTCCAGAA

Product: carbamoyl-phosphate synthase L chain, ATP-binding

Products: NA

Alternate protein names: Biotin carboxylase; Biotin carboxyl carrier protein; BCCP [H]

Number of amino acids: Translated: 634; Mature: 633

Protein sequence:

>634_residues
MTNSLAAVLESVLVANRGEIALRVMRACRKYGVRTIAIYTDLDVDAPHVRAADDAVHVSSYLDIDAVVAAAVASGATAVH
PGYGFLSERSAFVRAVEAAGVVFVGPPADVMDKMGRKDAAREIAVAAGVPVVPRGEDAGFPVLVKAAAGGGGKGMRVVRE
EADLEEAKAAAAREALAAFGDDTLLIEKYVERGRHIEVQIMADAHGHVVHLDERDCSTQRRHQKVLEEAPAPTISPEVRE
LVTSSAVALAKQVGYVNAGTVEFLVDDDTGEAYFLEMNTRLQVEHPVTELIHHDLDLVLHQLLVALGHPLEIEQDNVRPS
GHAIEARVYAEDSFGGFLPQAGRTSIVRWPAGVRVDHALEPDQVVSTSYDPMLGKVIVHGPDRESARRALVDALDRTAIL
GLTTNVGFLRALVASEEFRDAAIDTAWLDRNSVPAPDDDLPRVFVAWVSAMLAAGHDSGQPFRADGWRSGADPAPTIVEL
DRPVVVDRFAGLVDGRAVRQVAAADHVLTLEVDGRVHSAVVNVQPHVAEVVHHGQRFVFERPDVFGDHAVDVGDGAIAAP
MPGTVLDVRVEPGATVVAGDVLGVLEAMKMELTLKAPFDGTVSQVGATIGAQVALGARLFVVEPHAEAEEEEAG

Sequences:

>Translated_634_residues
MTNSLAAVLESVLVANRGEIALRVMRACRKYGVRTIAIYTDLDVDAPHVRAADDAVHVSSYLDIDAVVAAAVASGATAVH
PGYGFLSERSAFVRAVEAAGVVFVGPPADVMDKMGRKDAAREIAVAAGVPVVPRGEDAGFPVLVKAAAGGGGKGMRVVRE
EADLEEAKAAAAREALAAFGDDTLLIEKYVERGRHIEVQIMADAHGHVVHLDERDCSTQRRHQKVLEEAPAPTISPEVRE
LVTSSAVALAKQVGYVNAGTVEFLVDDDTGEAYFLEMNTRLQVEHPVTELIHHDLDLVLHQLLVALGHPLEIEQDNVRPS
GHAIEARVYAEDSFGGFLPQAGRTSIVRWPAGVRVDHALEPDQVVSTSYDPMLGKVIVHGPDRESARRALVDALDRTAIL
GLTTNVGFLRALVASEEFRDAAIDTAWLDRNSVPAPDDDLPRVFVAWVSAMLAAGHDSGQPFRADGWRSGADPAPTIVEL
DRPVVVDRFAGLVDGRAVRQVAAADHVLTLEVDGRVHSAVVNVQPHVAEVVHHGQRFVFERPDVFGDHAVDVGDGAIAAP
MPGTVLDVRVEPGATVVAGDVLGVLEAMKMELTLKAPFDGTVSQVGATIGAQVALGARLFVVEPHAEAEEEEAG
>Mature_633_residues
TNSLAAVLESVLVANRGEIALRVMRACRKYGVRTIAIYTDLDVDAPHVRAADDAVHVSSYLDIDAVVAAAVASGATAVHP
GYGFLSERSAFVRAVEAAGVVFVGPPADVMDKMGRKDAAREIAVAAGVPVVPRGEDAGFPVLVKAAAGGGGKGMRVVREE
ADLEEAKAAAAREALAAFGDDTLLIEKYVERGRHIEVQIMADAHGHVVHLDERDCSTQRRHQKVLEEAPAPTISPEVREL
VTSSAVALAKQVGYVNAGTVEFLVDDDTGEAYFLEMNTRLQVEHPVTELIHHDLDLVLHQLLVALGHPLEIEQDNVRPSG
HAIEARVYAEDSFGGFLPQAGRTSIVRWPAGVRVDHALEPDQVVSTSYDPMLGKVIVHGPDRESARRALVDALDRTAILG
LTTNVGFLRALVASEEFRDAAIDTAWLDRNSVPAPDDDLPRVFVAWVSAMLAAGHDSGQPFRADGWRSGADPAPTIVELD
RPVVVDRFAGLVDGRAVRQVAAADHVLTLEVDGRVHSAVVNVQPHVAEVVHHGQRFVFERPDVFGDHAVDVGDGAIAAPM
PGTVLDVRVEPGATVVAGDVLGVLEAMKMELTLKAPFDGTVSQVGATIGAQVALGARLFVVEPHAEAEEEEAG

Specific function: This protein carries two functions:biotin carboxyl carrier protein and biotin carboxyltransferase [H]

COG id: COG4770

COG function: function code I; Acetyl/propionyl-CoA carboxylase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 biotinyl-binding domain [H]

Homologues:

Organism=Homo sapiens, GI116805327, Length=698, Percent_Identity=37.2492836676218, Blast_Score=400, Evalue=1e-111,
Organism=Homo sapiens, GI189095269, Length=674, Percent_Identity=37.8338278931751, Blast_Score=391, Evalue=1e-108,
Organism=Homo sapiens, GI65506442, Length=674, Percent_Identity=37.8338278931751, Blast_Score=390, Evalue=1e-108,
Organism=Homo sapiens, GI295821183, Length=653, Percent_Identity=38.43797856049, Blast_Score=374, Evalue=1e-103,
Organism=Homo sapiens, GI106049528, Length=451, Percent_Identity=47.8935698447894, Blast_Score=367, Evalue=1e-101,
Organism=Homo sapiens, GI106049295, Length=451, Percent_Identity=47.8935698447894, Blast_Score=367, Evalue=1e-101,
Organism=Homo sapiens, GI106049292, Length=451, Percent_Identity=47.8935698447894, Blast_Score=367, Evalue=1e-101,
Organism=Homo sapiens, GI38679971, Length=702, Percent_Identity=28.9173789173789, Blast_Score=242, Evalue=9e-64,
Organism=Homo sapiens, GI38679977, Length=702, Percent_Identity=28.9173789173789, Blast_Score=241, Evalue=1e-63,
Organism=Homo sapiens, GI38679967, Length=702, Percent_Identity=28.9173789173789, Blast_Score=241, Evalue=1e-63,
Organism=Homo sapiens, GI38679974, Length=702, Percent_Identity=28.9173789173789, Blast_Score=241, Evalue=1e-63,
Organism=Homo sapiens, GI38679960, Length=702, Percent_Identity=28.9173789173789, Blast_Score=241, Evalue=1e-63,
Organism=Homo sapiens, GI134142062, Length=729, Percent_Identity=29.0809327846365, Blast_Score=225, Evalue=8e-59,
Organism=Escherichia coli, GI1789654, Length=447, Percent_Identity=43.1767337807606, Blast_Score=341, Evalue=7e-95,
Organism=Caenorhabditis elegans, GI71987519, Length=653, Percent_Identity=41.3476263399694, Blast_Score=419, Evalue=1e-117,
Organism=Caenorhabditis elegans, GI17567343, Length=684, Percent_Identity=38.3040935672515, Blast_Score=389, Evalue=1e-108,
Organism=Caenorhabditis elegans, GI17562816, Length=448, Percent_Identity=44.8660714285714, Blast_Score=334, Evalue=8e-92,
Organism=Caenorhabditis elegans, GI133931226, Length=668, Percent_Identity=26.9461077844311, Blast_Score=208, Evalue=7e-54,
Organism=Caenorhabditis elegans, GI71997168, Length=735, Percent_Identity=26.1224489795918, Blast_Score=198, Evalue=6e-51,
Organism=Caenorhabditis elegans, GI71997163, Length=507, Percent_Identity=28.4023668639053, Blast_Score=189, Evalue=3e-48,
Organism=Saccharomyces cerevisiae, GI6319685, Length=488, Percent_Identity=38.5245901639344, Blast_Score=344, Evalue=2e-95,
Organism=Saccharomyces cerevisiae, GI6319695, Length=470, Percent_Identity=41.063829787234, Blast_Score=298, Evalue=1e-81,
Organism=Saccharomyces cerevisiae, GI6321376, Length=464, Percent_Identity=41.1637931034483, Blast_Score=295, Evalue=1e-80,
Organism=Saccharomyces cerevisiae, GI6324343, Length=720, Percent_Identity=28.3333333333333, Blast_Score=241, Evalue=3e-64,
Organism=Saccharomyces cerevisiae, GI6323863, Length=696, Percent_Identity=28.3045977011494, Blast_Score=228, Evalue=2e-60,
Organism=Drosophila melanogaster, GI24651757, Length=444, Percent_Identity=44.1441441441441, Blast_Score=368, Evalue=1e-102,
Organism=Drosophila melanogaster, GI281363050, Length=449, Percent_Identity=46.3251670378619, Blast_Score=335, Evalue=4e-92,
Organism=Drosophila melanogaster, GI24652224, Length=449, Percent_Identity=46.3251670378619, Blast_Score=335, Evalue=4e-92,
Organism=Drosophila melanogaster, GI24652222, Length=449, Percent_Identity=46.3251670378619, Blast_Score=335, Evalue=4e-92,
Organism=Drosophila melanogaster, GI24652220, Length=449, Percent_Identity=46.3251670378619, Blast_Score=335, Evalue=4e-92,
Organism=Drosophila melanogaster, GI24652218, Length=449, Percent_Identity=46.3251670378619, Blast_Score=335, Evalue=4e-92,
Organism=Drosophila melanogaster, GI24652212, Length=449, Percent_Identity=46.3251670378619, Blast_Score=335, Evalue=6e-92,
Organism=Drosophila melanogaster, GI24652210, Length=449, Percent_Identity=46.3251670378619, Blast_Score=335, Evalue=6e-92,
Organism=Drosophila melanogaster, GI24652214, Length=449, Percent_Identity=46.3251670378619, Blast_Score=335, Evalue=6e-92,
Organism=Drosophila melanogaster, GI19921944, Length=449, Percent_Identity=46.3251670378619, Blast_Score=335, Evalue=6e-92,
Organism=Drosophila melanogaster, GI24652216, Length=449, Percent_Identity=46.3251670378619, Blast_Score=335, Evalue=6e-92,
Organism=Drosophila melanogaster, GI24651759, Length=405, Percent_Identity=43.7037037037037, Blast_Score=326, Evalue=4e-89,
Organism=Drosophila melanogaster, GI161076409, Length=710, Percent_Identity=29.5774647887324, Blast_Score=255, Evalue=5e-68,
Organism=Drosophila melanogaster, GI24586458, Length=710, Percent_Identity=29.5774647887324, Blast_Score=255, Evalue=8e-68,
Organism=Drosophila melanogaster, GI161076407, Length=710, Percent_Identity=29.5774647887324, Blast_Score=255, Evalue=9e-68,
Organism=Drosophila melanogaster, GI24586460, Length=710, Percent_Identity=29.5774647887324, Blast_Score=255, Evalue=9e-68,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011761
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR001882
- InterPro:   IPR011764
- InterPro:   IPR005482
- InterPro:   IPR000089
- InterPro:   IPR005479
- InterPro:   IPR005481
- InterPro:   IPR013817
- InterPro:   IPR016185
- InterPro:   IPR011054
- InterPro:   IPR011053 [H]

Pfam domain/function: PF02785 Biotin_carb_C; PF00364 Biotin_lipoyl; PF00289 CPSase_L_chain; PF02786 CPSase_L_D2 [H]

EC number: =6.3.4.14 [H]

Molecular weight: Translated: 67455; Mature: 67324

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: PS50975 ATP_GRASP ; PS00866 CPSASE_1 ; PS00867 CPSASE_2 ; PS50979 BC ; PS50968 BIOTINYL_LIPOYL ; PS00188 BIOTIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNSLAAVLESVLVANRGEIALRVMRACRKYGVRTIAIYTDLDVDAPHVRAADDAVHVSS
CCCHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCCCCCCCHHHH
YLDIDAVVAAAVASGATAVHPGYGFLSERSAFVRAVEAAGVVFVGPPADVMDKMGRKDAA
HCCHHHHHHHHHHCCCCEECCCCCCHHHHHHHHHHHHHCCEEEECCCHHHHHHCCCHHHH
REIAVAAGVPVVPRGEDAGFPVLVKAAAGGGGKGMRVVREEADLEEAKAAAAREALAAFG
HHHHHHCCCCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHCC
DDTLLIEKYVERGRHIEVQIMADAHGHVVHLDERDCSTQRRHQKVLEEAPAPTISPEVRE
CCHHHHHHHHHCCCEEEEEEEECCCCCEEEECCCCCHHHHHHHHHHHHCCCCCCCHHHHH
LVTSSAVALAKQVGYVNAGTVEFLVDDDTGEAYFLEMNTRLQVEHPVTELIHHDLDLVLH
HHHHHHHHHHHHCCCCCCCEEEEEEECCCCCEEEEEECCEEEECCCHHHHHHCCHHHHHH
QLLVALGHPLEIEQDNVRPSGHAIEARVYAEDSFGGFLPQAGRTSIVRWPAGVRVDHALE
HHHHHHCCCCEECCCCCCCCCCEEEEEEEEECCCCCCCCCCCCCCEEECCCCCEECCCCC
PDQVVSTSYDPMLGKVIVHGPDRESARRALVDALDRTAILGLTTNVGFLRALVASEEFRD
CCHHHCCCCCCCCCEEEEECCCHHHHHHHHHHHHHCCEEEEEECCHHHHHHHHHHHHHHH
AAIDTAWLDRNSVPAPDDDLPRVFVAWVSAMLAAGHDSGQPFRADGWRSGADPAPTIVEL
HHCCHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEEC
DRPVVVDRFAGLVDGRAVRQVAAADHVLTLEVDGRVHSAVVNVQPHVAEVVHHGQRFVFE
CCCCHHHHHHHHHCCHHHHHHHHCCEEEEEEECCCEEEEEEECCHHHHHHHHCCCCEEEE
RPDVFGDHAVDVGDGAIAAPMPGTVLDVRVEPGATVVAGDVLGVLEAMKMELTLKAPFDG
CCCCCCCCCEECCCCCEECCCCCCEEEEEECCCCEEEHHHHHHHHHHHEEEEEEECCCCC
TVSQVGATIGAQVALGARLFVVEPHAEAEEEEAG
HHHHHHHHHCCCEEECEEEEEECCCCCCCCCCCC
>Mature Secondary Structure 
TNSLAAVLESVLVANRGEIALRVMRACRKYGVRTIAIYTDLDVDAPHVRAADDAVHVSS
CCHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCCCCCCCHHHH
YLDIDAVVAAAVASGATAVHPGYGFLSERSAFVRAVEAAGVVFVGPPADVMDKMGRKDAA
HCCHHHHHHHHHHCCCCEECCCCCCHHHHHHHHHHHHHCCEEEECCCHHHHHHCCCHHHH
REIAVAAGVPVVPRGEDAGFPVLVKAAAGGGGKGMRVVREEADLEEAKAAAAREALAAFG
HHHHHHCCCCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHCC
DDTLLIEKYVERGRHIEVQIMADAHGHVVHLDERDCSTQRRHQKVLEEAPAPTISPEVRE
CCHHHHHHHHHCCCEEEEEEEECCCCCEEEECCCCCHHHHHHHHHHHHCCCCCCCHHHHH
LVTSSAVALAKQVGYVNAGTVEFLVDDDTGEAYFLEMNTRLQVEHPVTELIHHDLDLVLH
HHHHHHHHHHHHCCCCCCCEEEEEEECCCCCEEEEEECCEEEECCCHHHHHHCCHHHHHH
QLLVALGHPLEIEQDNVRPSGHAIEARVYAEDSFGGFLPQAGRTSIVRWPAGVRVDHALE
HHHHHHCCCCEECCCCCCCCCCEEEEEEEEECCCCCCCCCCCCCCEEECCCCCEECCCCC
PDQVVSTSYDPMLGKVIVHGPDRESARRALVDALDRTAILGLTTNVGFLRALVASEEFRD
CCHHHCCCCCCCCCEEEEECCCHHHHHHHHHHHHHCCEEEEEECCHHHHHHHHHHHHHHH
AAIDTAWLDRNSVPAPDDDLPRVFVAWVSAMLAAGHDSGQPFRADGWRSGADPAPTIVEL
HHCCHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEEC
DRPVVVDRFAGLVDGRAVRQVAAADHVLTLEVDGRVHSAVVNVQPHVAEVVHHGQRFVFE
CCCCHHHHHHHHHCCHHHHHHHHCCEEEEEEECCCEEEEEEECCHHHHHHHHCCCCEEEE
RPDVFGDHAVDVGDGAIAAPMPGTVLDVRVEPGATVVAGDVLGVLEAMKMELTLKAPFDG
CCCCCCCCCEECCCCCEECCCCCCEEEEEECCCCEEEHHHHHHHHHHHEEEEEEECCCCC
TVSQVGATIGAQVALGARLFVVEPHAEAEEEEAG
HHHHHHHHHCCCEEECEEEEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]