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The map label for this gene is aldH [H]

Identifier: 119714309

GI number: 119714309

Start: 41511

End: 43124

Strand: Reverse

Name: aldH [H]

Synonym: Noca_0037

Alternate gene names: 119714309

Gene position: 43124-41511 (Counterclockwise)

Preceding gene: 119714310

Following gene: 119714308

Centisome position: 0.86

GC content: 74.6

Gene sequence:

>1614_bases
ATGACAACCGAGACCACCGAGACCACCGAGACCGTCACGGGCGACCAGCTCGTCGCCGGTGCGGCCACGCGCGGCTCGAG
CGGTGTCTTCCACGCAGTCGATCCGCGCACCGGCGAGGAGCTGGCGACGGCCTTCGCCGAGGCGACCGTCGCCGAGGTGG
ACCGAGCGGTCGAGGCCGCCGTGGATGCGTTCGCCTCCTTCCGTGACTGGGACGACGCGCGTCGCGCCGACCTCCTCGAC
GCGATCGCCGCGGCCCTCGTGCACGACGGTTCGGCGATCCTCTCGGCTGTGGAGGCGGAGACCGCGCTCCCCCGCGCCCG
CGCCGAGGGCGAGCTGGTCCGCACCGCCGAGCAGTTCCGCGCCTTCGCCCGGGTGCTGCGGCAGGGCTGGCACCGCGACG
CGCTCGTCGACCCGCCGGACCCGGGGGCCGTGCCCGTCCCGCGCCCCGACGTGCGCCGGATCAACGTGCCCGTCGGCCCG
GTCGCGGTGTTCGGCGCGAGCAACTTCCCCCTGGCATTCAGCACGCCGGGCGGCGACACGGCCGCCGCGCTCGCGGCCGG
CTGCCCGGTGGTGGTCAAGGGCCACCCCAGCCATCCCGCGACCAGCGAGCTGTGCGGACGTGCCATCGTGCGGGCCCTTC
GCGAGCACGACGCCCCTGCCGGCACCTTCTCCCTCCTGCAGAGCACCCGGAACGAGGTGGGCGCCGCGCTCGTGCAGCAC
CCGCAGGTGGCCGCGGTCGGCTTCACCGGGTCGGAGGCCGGCGGGCGAGCCTTGTTCGACCTCGCCTCGCGGCGACCGAC
GCCGATCCCGGTGTACGCCGAGATGGGCAGCCTGAACCCCGTCCTGGTGACCGTGGCCGCTCTCGAGGCGCGCGCGGACG
CGATCGCGCAAGGACTCTCCGGCTCCTTCCTCTTCTGCGCCGGGCAGTACTGCACCAAGCCGGGCCTCGTGCTCGTGCCC
GAGGGCCCCGCGGGCGACCGCTTCGTGGGCCTGCTCGCCACGACGGTCCGCGAGCAGGAGGCGTTGCCGGTGCTGGCCGC
CAACATCGGCAGCGCCTTCGACACCTCGGTCGGCGCGCTCGAGGCTGCTCTCGGAGACGACGCCGTGGTGCACGGGCAGG
CCCGCCGCCGGGGTCTGGAGCGCGAGGCCGCACTCGTGGTCGTGGACGCCGCGCGCGTGCGCGAGGCTCCCGATCTCCTC
GTCGAGCACTTCGGGCCGCTGTCGGTCGTGGTGCGATACGCGAGCCCCACCGACGTGCTGGACGTCATCGCGCAGGTGCC
CGGCAGCCTCACCGCCACCGTGCACGGCGAGCCCGACGACCACGACCTGGTCCGTCAGCTCCTGCCCGCGCTGGTGGAGA
AGGCCGGCCGGGTGCTGTGGAACGGATACCCGACGGGAGTGTCCGTGACGGGCGCGATGATGCACGGCGGGCCGTACCCC
TCCTCCACCTTCCCCGCGCACACCTCGGTGGGGTGGACCGCCATCCGCCGCTTCCTGCGGCCGGTCACGTTCCAGAACTT
CCCCGACGAACTGCTGCCGGCCCCGCTGCGCGCCGACAACCCCCTGGCCGCTCCCCGCCTCGTCGACGGGGCGCTGAGCA
CCGGTCCCAGCTGA

Upstream 100 bases:

>100_bases
TCCTCGCCAAGGTCGCCGCCGGGGCCCCCCTGCGGGGTACCTATCCGCCGGATGCGCCGGCCAAGGCCGAGTACCGGCGC
TGGGCCCAGGAGGAAGACGC

Downstream 100 bases:

>100_bases
CGCGATCTTCCGCGCCGGCACCACCTTCGAGGTCCCGAGGAGCACATTCATGCCCCATGTAGGCGACGCGATGATCGACG
CGATCGCGAGCGCAGGCGTC

Product: aldehyde dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 537; Mature: 536

Protein sequence:

>537_residues
MTTETTETTETVTGDQLVAGAATRGSSGVFHAVDPRTGEELATAFAEATVAEVDRAVEAAVDAFASFRDWDDARRADLLD
AIAAALVHDGSAILSAVEAETALPRARAEGELVRTAEQFRAFARVLRQGWHRDALVDPPDPGAVPVPRPDVRRINVPVGP
VAVFGASNFPLAFSTPGGDTAAALAAGCPVVVKGHPSHPATSELCGRAIVRALREHDAPAGTFSLLQSTRNEVGAALVQH
PQVAAVGFTGSEAGGRALFDLASRRPTPIPVYAEMGSLNPVLVTVAALEARADAIAQGLSGSFLFCAGQYCTKPGLVLVP
EGPAGDRFVGLLATTVREQEALPVLAANIGSAFDTSVGALEAALGDDAVVHGQARRRGLEREAALVVVDAARVREAPDLL
VEHFGPLSVVVRYASPTDVLDVIAQVPGSLTATVHGEPDDHDLVRQLLPALVEKAGRVLWNGYPTGVSVTGAMMHGGPYP
SSTFPAHTSVGWTAIRRFLRPVTFQNFPDELLPAPLRADNPLAAPRLVDGALSTGPS

Sequences:

>Translated_537_residues
MTTETTETTETVTGDQLVAGAATRGSSGVFHAVDPRTGEELATAFAEATVAEVDRAVEAAVDAFASFRDWDDARRADLLD
AIAAALVHDGSAILSAVEAETALPRARAEGELVRTAEQFRAFARVLRQGWHRDALVDPPDPGAVPVPRPDVRRINVPVGP
VAVFGASNFPLAFSTPGGDTAAALAAGCPVVVKGHPSHPATSELCGRAIVRALREHDAPAGTFSLLQSTRNEVGAALVQH
PQVAAVGFTGSEAGGRALFDLASRRPTPIPVYAEMGSLNPVLVTVAALEARADAIAQGLSGSFLFCAGQYCTKPGLVLVP
EGPAGDRFVGLLATTVREQEALPVLAANIGSAFDTSVGALEAALGDDAVVHGQARRRGLEREAALVVVDAARVREAPDLL
VEHFGPLSVVVRYASPTDVLDVIAQVPGSLTATVHGEPDDHDLVRQLLPALVEKAGRVLWNGYPTGVSVTGAMMHGGPYP
SSTFPAHTSVGWTAIRRFLRPVTFQNFPDELLPAPLRADNPLAAPRLVDGALSTGPS
>Mature_536_residues
TTETTETTETVTGDQLVAGAATRGSSGVFHAVDPRTGEELATAFAEATVAEVDRAVEAAVDAFASFRDWDDARRADLLDA
IAAALVHDGSAILSAVEAETALPRARAEGELVRTAEQFRAFARVLRQGWHRDALVDPPDPGAVPVPRPDVRRINVPVGPV
AVFGASNFPLAFSTPGGDTAAALAAGCPVVVKGHPSHPATSELCGRAIVRALREHDAPAGTFSLLQSTRNEVGAALVQHP
QVAAVGFTGSEAGGRALFDLASRRPTPIPVYAEMGSLNPVLVTVAALEARADAIAQGLSGSFLFCAGQYCTKPGLVLVPE
GPAGDRFVGLLATTVREQEALPVLAANIGSAFDTSVGALEAALGDDAVVHGQARRRGLEREAALVVVDAARVREAPDLLV
EHFGPLSVVVRYASPTDVLDVIAQVPGSLTATVHGEPDDHDLVRQLLPALVEKAGRVLWNGYPTGVSVTGAMMHGGPYPS
STFPAHTSVGWTAIRRFLRPVTFQNFPDELLPAPLRADNPLAAPRLVDGALSTGPS

Specific function: Catalyzes the oxidation of long-chain aliphatic aldehydes to acids. May be implicated in controlling luminescence as it catalyzes the oxidation of the fatty aldehyde substrate for the light-emitting reaction [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldehyde dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4507229, Length=428, Percent_Identity=25.9345794392523, Blast_Score=76, Evalue=1e-13,
Organism=Homo sapiens, GI153266822, Length=463, Percent_Identity=27.2138228941685, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI25777721, Length=437, Percent_Identity=25.629290617849, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI1788042, Length=507, Percent_Identity=28.0078895463511, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI87081896, Length=424, Percent_Identity=29.2452830188679, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI1789015, Length=406, Percent_Identity=26.3546798029557, Blast_Score=73, Evalue=6e-14,
Organism=Escherichia coli, GI1787558, Length=458, Percent_Identity=27.292576419214, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1786504, Length=311, Percent_Identity=27.6527331189711, Blast_Score=64, Evalue=3e-11,
Organism=Escherichia coli, GI1787250, Length=425, Percent_Identity=26.5882352941176, Blast_Score=64, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI71995606, Length=299, Percent_Identity=29.7658862876254, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI71995613, Length=299, Percent_Identity=29.7658862876254, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17534119, Length=441, Percent_Identity=25.6235827664399, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI25143874, Length=318, Percent_Identity=26.7295597484277, Blast_Score=72, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI25143876, Length=318, Percent_Identity=26.7295597484277, Blast_Score=72, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17551164, Length=454, Percent_Identity=24.2290748898678, Blast_Score=72, Evalue=8e-13,
Organism=Saccharomyces cerevisiae, GI6319478, Length=520, Percent_Identity=24.4230769230769, Blast_Score=87, Evalue=5e-18,
Organism=Saccharomyces cerevisiae, GI6323822, Length=315, Percent_Identity=28.2539682539683, Blast_Score=70, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24650465, Length=470, Percent_Identity=24.468085106383, Blast_Score=73, Evalue=6e-13,
Organism=Drosophila melanogaster, GI281362580, Length=354, Percent_Identity=27.1186440677966, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI62472918, Length=354, Percent_Identity=27.1186440677966, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI62472926, Length=354, Percent_Identity=27.1186440677966, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI62472936, Length=354, Percent_Identity=27.1186440677966, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI21356737, Length=354, Percent_Identity=27.1186440677966, Blast_Score=70, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016161
- InterPro:   IPR016163
- InterPro:   IPR016162
- InterPro:   IPR015590 [H]

Pfam domain/function: PF00171 Aldedh [H]

EC number: =1.2.1.4 [H]

Molecular weight: Translated: 55901; Mature: 55769

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTETTETTETVTGDQLVAGAATRGSSGVFHAVDPRTGEELATAFAEATVAEVDRAVEAA
CCCCCCCCCCCCCCCHHEECCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHH
VDAFASFRDWDDARRADLLDAIAAALVHDGSAILSAVEAETALPRARAEGELVRTAEQFR
HHHHHHHHCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHCCCHHHHHHHHHH
AFARVLRQGWHRDALVDPPDPGAVPVPRPDVRRINVPVGPVAVFGASNFPLAFSTPGGDT
HHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCEEEECCCCCCEEEECCCCCH
AAALAAGCPVVVKGHPSHPATSELCGRAIVRALREHDAPAGTFSLLQSTRNEVGAALVQH
HHHHHCCCCEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCC
PQVAAVGFTGSEAGGRALFDLASRRPTPIPVYAEMGSLNPVLVTVAALEARADAIAQGLS
CCEEEEECCCCCCCCHHHHHHHCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHCCC
GSFLFCAGQYCTKPGLVLVPEGPAGDRFVGLLATTVREQEALPVLAANIGSAFDTSVGAL
CCEEEEECHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCHHHHHCCCHHHHHHHHH
EAALGDDAVVHGQARRRGLEREAALVVVDAARVREAPDLLVEHFGPLSVVVRYASPTDVL
HHHCCCCCEEECHHHHCCCCCCCEEEEEEHHHHHCCHHHHHHCCCCHHEEEECCCCHHHH
DVIAQVPGSLTATVHGEPDDHDLVRQLLPALVEKAGRVLWNGYPTGVSVTGAMMHGGPYP
HHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCEEECCCCCCCEEEEHEECCCCCC
SSTFPAHTSVGWTAIRRFLRPVTFQNFPDELLPAPLRADNPLAAPRLVDGALSTGPS
CCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHCCCCCCCCCCCCCCHHHHHHHCCCCC
>Mature Secondary Structure 
TTETTETTETVTGDQLVAGAATRGSSGVFHAVDPRTGEELATAFAEATVAEVDRAVEAA
CCCCCCCCCCCCCCHHEECCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHH
VDAFASFRDWDDARRADLLDAIAAALVHDGSAILSAVEAETALPRARAEGELVRTAEQFR
HHHHHHHHCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHCCCHHHHHHHHHH
AFARVLRQGWHRDALVDPPDPGAVPVPRPDVRRINVPVGPVAVFGASNFPLAFSTPGGDT
HHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCEEEECCCCCCEEEECCCCCH
AAALAAGCPVVVKGHPSHPATSELCGRAIVRALREHDAPAGTFSLLQSTRNEVGAALVQH
HHHHHCCCCEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCC
PQVAAVGFTGSEAGGRALFDLASRRPTPIPVYAEMGSLNPVLVTVAALEARADAIAQGLS
CCEEEEECCCCCCCCHHHHHHHCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHCCC
GSFLFCAGQYCTKPGLVLVPEGPAGDRFVGLLATTVREQEALPVLAANIGSAFDTSVGAL
CCEEEEECHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCHHHHHCCCHHHHHHHHH
EAALGDDAVVHGQARRRGLEREAALVVVDAARVREAPDLLVEHFGPLSVVVRYASPTDVL
HHHCCCCCEEECHHHHCCCCCCCEEEEEEHHHHHCCHHHHHHCCCCHHEEEECCCCHHHH
DVIAQVPGSLTATVHGEPDDHDLVRQLLPALVEKAGRVLWNGYPTGVSVTGAMMHGGPYP
HHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCEEECCCCCCCEEEEHEECCCCCC
SSTFPAHTSVGWTAIRRFLRPVTFQNFPDELLPAPLRADNPLAAPRLVDGALSTGPS
CCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHCCCCCCCCCCCCCCHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8527447; 10903148 [H]