| Definition | Nocardioides sp. JS614 chromosome, complete genome. |
|---|---|
| Accession | NC_008699 |
| Length | 4,985,871 |
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The map label for this gene is pstP [H]
Identifier: 119714298
GI number: 119714298
Start: 29771
End: 31087
Strand: Reverse
Name: pstP [H]
Synonym: Noca_0026
Alternate gene names: 119714298
Gene position: 31087-29771 (Counterclockwise)
Preceding gene: 119714299
Following gene: 119714297
Centisome position: 0.62
GC content: 74.26
Gene sequence:
>1317_bases ATGACCGACACGCCAGCAGCGGCGCCGAGCCTGCGCCTGCGGTTCGCCGCGATCTCCGACGTCGGGCGGGTCCGCAAGGA CAACCAGGACTCCGGGTACGTCGGCCCGTGGCTGGTCGCGGTCTGCGACGGCGTCGGCGGCGCGGCCCGCGGTGACATCG CCTCCAGCACCGCGATCGCCCAGCTGCGGCGGCTCGACGTGTCCCCGAGCGGCGAGTCCGCCGACGACCTGCTCACCAAG GTCGCCGGCGCCCTGCACCGGGCCCACGAGCGGATCAACGAGCTCGCCGCCGAGGACCCCGCACTCGACGGCACCAGCAC CACCGCGACGGTCGCGCTCTTCGACGGCGCGCGGGTCGCGATGGGCCACGTCGGCGACAGCCGGGCCTACCTGTTCCGCG ACGGCGAGATCACCCGGCTCACCTCCGACCACACCTTCGTGCAGACCCTGATCGACGAGGGCCGGATCACCGAGGCCGAG GCCCGGGTCCACCCGCACCGCAACCTGATCCTCAACGCCCTGGGTGGTCCCGGCGACGTCGAGCCCGACCTCTTCATGAT CGAGCTGGCGCCGAAGGACCGGCTGCTGCTGTGCAGCGACGGCGCCAGCGGGGTCCTCGACGACGACCGGCTGGCCGACA TCCTCGCCACCGGGAGCCCGGAGTTCGCCTCGGTCGAGCTGGTCCGCGCCAGCCTCGAGGCCGGCAGCTCCGACAACGTC ACCTGCCTGGTCGCCGACGCCGTCGACGCCGCCGAGCCGCCCGGCCCCGGCGAGGCGGAGGAGCCGGTGCTGGTCGGCGC GGCCGCCGAGCGGCGCCTGCACCGCCAGCGCGGCGGCATGGGCAGCCTGTTCCGCGGCCACCGGTCGGGCGACACCGGCG AGCTCGAGCCGGTGCAGGCCGAGATCCTCGACCTGCCCTACGCGATCACCGCCGACCCGATCGACCCGGAGGAGGCGCGC TACGCGCCGCGCCCGCCGCGCCGCTTCGTGTGGCTCAAGCGGCTGCTGACGCTCGTGCTCCTGGTCGGCCTCGCCTGGGT CGGCATCGCCGCCGCCTGGTCGTGGACCCAGGGGCAGTACTACGTCGGCGAGCAGGACGGCACGGTCGTCATCTTCCGCG GCGTCAACACCGAGCTGGCCGGCCTCTCGCTCTCCGAGCCCTATGAGAGCTCGGACGTCGAGCTGGACCGGCTCGGCGAG GTCGAGGCCGACCGGGTCCGCGAGGGCATCGCCTACGACAATCTCGAGGACGCCGAGCAGAAGGTCCGCGACCTCGCCGC CCGGCAGTCCCCCGCCTCCGAGAGCTCGGCCGGCTGA
Upstream 100 bases:
>100_bases ACGTACGTCGGCACCGTCCGCATCACCCAACCCACCACGATCACGCTCGGCACCCAGGTCCGGATCGGCAAGACGATCCT GGAGCTCAGGAAGTAGCGCG
Downstream 100 bases:
>100_bases TGTCCCAGACGTCCTCCAGCCTGATGGGGTTCGTGCACCGCCGCCGCCGGGGTGCCGAGCTGTTCCTGCTGATCCTCGCG CTGGCCGTCGGCATCGGCGC
Product: protein phosphatase 2C domain-containing protein
Products: NA
Alternate protein names: Mycobacterial Ser/Thr phosphatase; Mstp; Possible serine/threonine phosphatase Ppp [H]
Number of amino acids: Translated: 438; Mature: 437
Protein sequence:
>438_residues MTDTPAAAPSLRLRFAAISDVGRVRKDNQDSGYVGPWLVAVCDGVGGAARGDIASSTAIAQLRRLDVSPSGESADDLLTK VAGALHRAHERINELAAEDPALDGTSTTATVALFDGARVAMGHVGDSRAYLFRDGEITRLTSDHTFVQTLIDEGRITEAE ARVHPHRNLILNALGGPGDVEPDLFMIELAPKDRLLLCSDGASGVLDDDRLADILATGSPEFASVELVRASLEAGSSDNV TCLVADAVDAAEPPGPGEAEEPVLVGAAAERRLHRQRGGMGSLFRGHRSGDTGELEPVQAEILDLPYAITADPIDPEEAR YAPRPPRRFVWLKRLLTLVLLVGLAWVGIAAAWSWTQGQYYVGEQDGTVVIFRGVNTELAGLSLSEPYESSDVELDRLGE VEADRVREGIAYDNLEDAEQKVRDLAARQSPASESSAG
Sequences:
>Translated_438_residues MTDTPAAAPSLRLRFAAISDVGRVRKDNQDSGYVGPWLVAVCDGVGGAARGDIASSTAIAQLRRLDVSPSGESADDLLTK VAGALHRAHERINELAAEDPALDGTSTTATVALFDGARVAMGHVGDSRAYLFRDGEITRLTSDHTFVQTLIDEGRITEAE ARVHPHRNLILNALGGPGDVEPDLFMIELAPKDRLLLCSDGASGVLDDDRLADILATGSPEFASVELVRASLEAGSSDNV TCLVADAVDAAEPPGPGEAEEPVLVGAAAERRLHRQRGGMGSLFRGHRSGDTGELEPVQAEILDLPYAITADPIDPEEAR YAPRPPRRFVWLKRLLTLVLLVGLAWVGIAAAWSWTQGQYYVGEQDGTVVIFRGVNTELAGLSLSEPYESSDVELDRLGE VEADRVREGIAYDNLEDAEQKVRDLAARQSPASESSAG >Mature_437_residues TDTPAAAPSLRLRFAAISDVGRVRKDNQDSGYVGPWLVAVCDGVGGAARGDIASSTAIAQLRRLDVSPSGESADDLLTKV AGALHRAHERINELAAEDPALDGTSTTATVALFDGARVAMGHVGDSRAYLFRDGEITRLTSDHTFVQTLIDEGRITEAEA RVHPHRNLILNALGGPGDVEPDLFMIELAPKDRLLLCSDGASGVLDDDRLADILATGSPEFASVELVRASLEAGSSDNVT CLVADAVDAAEPPGPGEAEEPVLVGAAAERRLHRQRGGMGSLFRGHRSGDTGELEPVQAEILDLPYAITADPIDPEEARY APRPPRRFVWLKRLLTLVLLVGLAWVGIAAAWSWTQGQYYVGEQDGTVVIFRGVNTELAGLSLSEPYESSDVELDRLGEV EADRVREGIAYDNLEDAEQKVRDLAARQSPASESSAG
Specific function: The only predicted protein phosphatase in M.tuberculosis, it dephosphorylates at least 5 protein kinases (pknA, pknB, pknD, pknE and pknF) and the penicillin-binding protein PBPA [H]
COG id: COG0631
COG function: function code T; Serine/threonine protein phosphatase
Gene ontology:
Cell location: Cell membrane; Single-pass membrane protein (Potential). Note=May be localized to the outside of the cell [H]
Metaboloic importance: NA
Operon status: Not Known
Operon components: None
Similarity: Contains 1 PP2C-like domain [H]
Homologues:
None
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR015655 - InterPro: IPR001932 - InterPro: IPR014045 [H]
Pfam domain/function: PF00481 PP2C [H]
EC number: =3.1.3.16 [H]
Molecular weight: Translated: 46673; Mature: 46542
Theoretical pI: Translated: 4.33; Mature: 4.33
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.7 %Cys (Translated Protein) 0.9 %Met (Translated Protein) 1.6 %Cys+Met (Translated Protein) 0.7 %Cys (Mature Protein) 0.7 %Met (Mature Protein) 1.4 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MTDTPAAAPSLRLRFAAISDVGRVRKDNQDSGYVGPWLVAVCDGVGGAARGDIASSTAIA CCCCCCCCCCCEEEEHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCCCCCCCHHHHHHH QLRRLDVSPSGESADDLLTKVAGALHRAHERINELAAEDPALDGTSTTATVALFDGARVA HHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCEEE MGHVGDSRAYLFRDGEITRLTSDHTFVQTLIDEGRITEAEARVHPHRNLILNALGGPGDV EECCCCCCEEEEECCCEEEEECCHHHHHHHHCCCCCCCHHHHCCCCCCEEEEECCCCCCC EPDLFMIELAPKDRLLLCSDGASGVLDDDRLADILATGSPEFASVELVRASLEAGSSDNV CCCEEEEEECCCCCEEEECCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCE TCLVADAVDAAEPPGPGEAEEPVLVGAAAERRLHRQRGGMGSLFRGHRSGDTGELEPVQA EEEEECCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHCCCCCHHHHCCCCCCCCCCCHHHH EILDLPYAITADPIDPEEARYAPRPPRRFVWLKRLLTLVLLVGLAWVGIAAAWSWTQGQY HHHCCCEEEECCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCEE YVGEQDGTVVIFRGVNTELAGLSLSEPYESSDVELDRLGEVEADRVREGIAYDNLEDAEQ EECCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCHHHCCCCCHHHHHHCCCCCCHHHHHH KVRDLAARQSPASESSAG HHHHHHHHCCCCCCCCCC >Mature Secondary Structure TDTPAAAPSLRLRFAAISDVGRVRKDNQDSGYVGPWLVAVCDGVGGAARGDIASSTAIA CCCCCCCCCCEEEEHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCCCCCCCHHHHHHH QLRRLDVSPSGESADDLLTKVAGALHRAHERINELAAEDPALDGTSTTATVALFDGARVA HHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCEEE MGHVGDSRAYLFRDGEITRLTSDHTFVQTLIDEGRITEAEARVHPHRNLILNALGGPGDV EECCCCCCEEEEECCCEEEEECCHHHHHHHHCCCCCCCHHHHCCCCCCEEEEECCCCCCC EPDLFMIELAPKDRLLLCSDGASGVLDDDRLADILATGSPEFASVELVRASLEAGSSDNV CCCEEEEEECCCCCEEEECCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCE TCLVADAVDAAEPPGPGEAEEPVLVGAAAERRLHRQRGGMGSLFRGHRSGDTGELEPVQA EEEEECCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHCCCCCHHHHCCCCCCCCCCCHHHH EILDLPYAITADPIDPEEARYAPRPPRRFVWLKRLLTLVLLVGLAWVGIAAAWSWTQGQY HHHCCCEEEECCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCEE YVGEQDGTVVIFRGVNTELAGLSLSEPYESSDVELDRLGEVEADRVREGIAYDNLEDAEQ EECCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCHHHCCCCCHHHHHHCCCCCCHHHHHH KVRDLAARQSPASESSAG HHHHHHHHCCCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 9634230; 12218036 [H]