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The map label for this gene is ftsW [H]

Identifier: 119714297

GI number: 119714297

Start: 28365

End: 29771

Strand: Reverse

Name: ftsW [H]

Synonym: Noca_0025

Alternate gene names: 119714297

Gene position: 29771-28365 (Counterclockwise)

Preceding gene: 119714298

Following gene: 119714296

Centisome position: 0.6

GC content: 71.07

Gene sequence:

>1407_bases
ATGTCCCAGACGTCCTCCAGCCTGATGGGGTTCGTGCACCGCCGCCGCCGGGGTGCCGAGCTGTTCCTGCTGATCCTCGC
GCTGGCCGTCGGCATCGGCGCGTACGCCGCCGTCGGCCTCGGCGTGGACCAGGAGGTCCCCGCGGACCTGATCGGCTACG
GCAGCTGGTTGGCCGCGCTGGTGATCGCCGCCCACGTGGTGATCCGGTTCGTCGCGCCGTACGCCGACCCGGTGCTGCTG
CCCGTCGTGGCCGCCCTGAACGGCCTCGGACTGGCGGTGATCCACCGGCTCGACCTCGCCAAGGCCGAGGCCGGCAACTT
CCACGGCTACGCCCAGCAGCAGCTGACCTGGATGACGCTCGGCGTGGTGCTGTTCGTCATCACGCTCCTCGCGCTGCGCG
ACCACCGGGTGCTCCAGCGGTTCACCTACACCAGCGGGCTCGCCGCGATCGTGCTGCTCCTGCTGCCGATGCTGCCCGGC
ATCGGGCGCACCATCAACGGCGCCCGGATCTGGATCCACCTCGGCCCGTTCAGCTTCCAGCCCGGCGAGGTCGCCAAGGT
GCTGCTGGTCGTCACCTTCGCCGGCTACCTGGTGCTGCACCGCGACGCGCTCGCGCTGGCCGGCCGGCGGGTGCTGTTCG
TCGACCTCCCCCGCGGCCGCGACCTCGGCCCGATCCTCGTGATGTGGGCGGTCAGCCTCGGCATCCTGGTCCGCCAGCAG
GACCTCGGCTCGAGCCTGCTGTTCTTCGGGCTGTTCCTGGTGATGCTCTACGTGGCCACCGAGCGGGGCGGCTGGCTGGT
GGTCGGCGCCCTGATGTTCGCGGGCGGCGCGACCGCGGCGTACTACCTCTTCCCCCACGTCCAGGTGCGCTTCGACATCT
GGCTGCACCCGTTCGACTACTACAACAAGAACGGCGACCAGGCCTTCCAGCCGGTCGAGGCGCAGTTCGGCATGGGTTGG
GGCGGCCTGATCGGCCGCGGCTTCGGCGACGGCGACCCCAACCGGGTGCCGTTCGCGGAGTCCGACTTCATCGTCGCCGC
GATCGGCGAGGAGCTCGGCCTGACCGCGGTCATCGCGGTGGTCCTCCTCTACGGGCTGATCGTCGAGCGGGCCCTGCGCA
CGGCGCTGATCTGCCGCGACGGCTTCGGCAAGCTGCTGTCCACCGGCCTCGGCAGCGTGTTCGCGCTCCAGGTGTTCGTG
GTGGTCGGCGGGGTGACCAGCCTGATCCCGCTGACCGGGCTCACCACGCCGTTCCTCTCGTACGGCGGCTCCTCGCTGGT
GGCGAACTGGGTGATCGTCGCGATCCTGCTGCGGATCTCCGACCAGGCCCGCCGCCCCACACCGCAGCTCTCCGACGACA
CCGCCGCGATCGGCGACGACGCCACCCAGGTGGTGCGCCTGTCGTGA

Upstream 100 bases:

>100_bases
TCCGCGAGGGCATCGCCTACGACAATCTCGAGGACGCCGAGCAGAAGGTCCGCGACCTCGCCGCCCGGCAGTCCCCCGCC
TCCGAGAGCTCGGCCGGCTG

Downstream 100 bases:

>100_bases
ACAAGCCGATCCGGACGATCTCGATGTTCTGCCTGCTGCTGTTCCTGGCGCTGATGCTGAACGCGACCTACCTGCAGTAC
TGGAAGGCCGGCCGGCTCAA

Product: cell cycle protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 468; Mature: 467

Protein sequence:

>468_residues
MSQTSSSLMGFVHRRRRGAELFLLILALAVGIGAYAAVGLGVDQEVPADLIGYGSWLAALVIAAHVVIRFVAPYADPVLL
PVVAALNGLGLAVIHRLDLAKAEAGNFHGYAQQQLTWMTLGVVLFVITLLALRDHRVLQRFTYTSGLAAIVLLLLPMLPG
IGRTINGARIWIHLGPFSFQPGEVAKVLLVVTFAGYLVLHRDALALAGRRVLFVDLPRGRDLGPILVMWAVSLGILVRQQ
DLGSSLLFFGLFLVMLYVATERGGWLVVGALMFAGGATAAYYLFPHVQVRFDIWLHPFDYYNKNGDQAFQPVEAQFGMGW
GGLIGRGFGDGDPNRVPFAESDFIVAAIGEELGLTAVIAVVLLYGLIVERALRTALICRDGFGKLLSTGLGSVFALQVFV
VVGGVTSLIPLTGLTTPFLSYGGSSLVANWVIVAILLRISDQARRPTPQLSDDTAAIGDDATQVVRLS

Sequences:

>Translated_468_residues
MSQTSSSLMGFVHRRRRGAELFLLILALAVGIGAYAAVGLGVDQEVPADLIGYGSWLAALVIAAHVVIRFVAPYADPVLL
PVVAALNGLGLAVIHRLDLAKAEAGNFHGYAQQQLTWMTLGVVLFVITLLALRDHRVLQRFTYTSGLAAIVLLLLPMLPG
IGRTINGARIWIHLGPFSFQPGEVAKVLLVVTFAGYLVLHRDALALAGRRVLFVDLPRGRDLGPILVMWAVSLGILVRQQ
DLGSSLLFFGLFLVMLYVATERGGWLVVGALMFAGGATAAYYLFPHVQVRFDIWLHPFDYYNKNGDQAFQPVEAQFGMGW
GGLIGRGFGDGDPNRVPFAESDFIVAAIGEELGLTAVIAVVLLYGLIVERALRTALICRDGFGKLLSTGLGSVFALQVFV
VVGGVTSLIPLTGLTTPFLSYGGSSLVANWVIVAILLRISDQARRPTPQLSDDTAAIGDDATQVVRLS
>Mature_467_residues
SQTSSSLMGFVHRRRRGAELFLLILALAVGIGAYAAVGLGVDQEVPADLIGYGSWLAALVIAAHVVIRFVAPYADPVLLP
VVAALNGLGLAVIHRLDLAKAEAGNFHGYAQQQLTWMTLGVVLFVITLLALRDHRVLQRFTYTSGLAAIVLLLLPMLPGI
GRTINGARIWIHLGPFSFQPGEVAKVLLVVTFAGYLVLHRDALALAGRRVLFVDLPRGRDLGPILVMWAVSLGILVRQQD
LGSSLLFFGLFLVMLYVATERGGWLVVGALMFAGGATAAYYLFPHVQVRFDIWLHPFDYYNKNGDQAFQPVEAQFGMGWG
GLIGRGFGDGDPNRVPFAESDFIVAAIGEELGLTAVIAVVLLYGLIVERALRTALICRDGFGKLLSTGLGSVFALQVFVV
VGGVTSLIPLTGLTTPFLSYGGSSLVANWVIVAILLRISDQARRPTPQLSDDTAAIGDDATQVVRLS

Specific function: This is a septum-peptidoglycan biosynthetic protein, involved in cell wall formation. Plays a role in the stabilization of the ftsZ ring during cell division [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786277, Length=350, Percent_Identity=30, Blast_Score=113, Evalue=3e-26,
Organism=Escherichia coli, GI1786853, Length=331, Percent_Identity=26.5861027190332, Blast_Score=84, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 50214; Mature: 50083

Theoretical pI: Translated: 8.41; Mature: 8.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQTSSSLMGFVHRRRRGAELFLLILALAVGIGAYAAVGLGVDQEVPADLIGYGSWLAAL
CCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHH
VIAAHVVIRFVAPYADPVLLPVVAALNGLGLAVIHRLDLAKAEAGNFHGYAQQQLTWMTL
HHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHH
GVVLFVITLLALRDHRVLQRFTYTSGLAAIVLLLLPMLPGIGRTINGARIWIHLGPFSFQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCC
PGEVAKVLLVVTFAGYLVLHRDALALAGRRVLFVDLPRGRDLGPILVMWAVSLGILVRQQ
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHH
DLGSSLLFFGLFLVMLYVATERGGWLVVGALMFAGGATAAYYLFPHVQVRFDIWLHPFDY
HCCCHHHHHHHHHHHHHHHCCCCCEEEEHHHHHCCCCCEEEEEECCEEEEEEEEECCHHH
YNKNGDQAFQPVEAQFGMGWGGLIGRGFGDGDPNRVPFAESDFIVAAIGEELGLTAVIAV
HCCCCCCCCCCHHHHCCCCCHHHHCCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHH
VLLYGLIVERALRTALICRDGFGKLLSTGLGSVFALQVFVVVGGVTSLIPLTGLTTPFLS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
YGGSSLVANWVIVAILLRISDQARRPTPQLSDDTAAIGDDATQVVRLS
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEECC
>Mature Secondary Structure 
SQTSSSLMGFVHRRRRGAELFLLILALAVGIGAYAAVGLGVDQEVPADLIGYGSWLAAL
CCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHH
VIAAHVVIRFVAPYADPVLLPVVAALNGLGLAVIHRLDLAKAEAGNFHGYAQQQLTWMTL
HHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHH
GVVLFVITLLALRDHRVLQRFTYTSGLAAIVLLLLPMLPGIGRTINGARIWIHLGPFSFQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCC
PGEVAKVLLVVTFAGYLVLHRDALALAGRRVLFVDLPRGRDLGPILVMWAVSLGILVRQQ
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHH
DLGSSLLFFGLFLVMLYVATERGGWLVVGALMFAGGATAAYYLFPHVQVRFDIWLHPFDY
HCCCHHHHHHHHHHHHHHHCCCCCEEEEHHHHHCCCCCEEEEEECCEEEEEEEEECCHHH
YNKNGDQAFQPVEAQFGMGWGGLIGRGFGDGDPNRVPFAESDFIVAAIGEELGLTAVIAV
HCCCCCCCCCCHHHHCCCCCHHHHCCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHH
VLLYGLIVERALRTALICRDGFGKLLSTGLGSVFALQVFVVVGGVTSLIPLTGLTTPFLS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
YGGSSLVANWVIVAILLRISDQARRPTPQLSDDTAAIGDDATQVVRLS
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]