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The map label for this gene is gluP [H]

Identifier: 119714290

GI number: 119714290

Start: 19941

End: 20861

Strand: Direct

Name: gluP [H]

Synonym: Noca_0018

Alternate gene names: 119714290

Gene position: 19941-20861 (Clockwise)

Preceding gene: 119714289

Following gene: 119714291

Centisome position: 0.4

GC content: 71.44

Gene sequence:

>921_bases
TTGTCCGAACACGCGACGCCCCCGGCCGGGGTGCCGACCTGCTATCGCCACCCCGGCCGCGAGGCGCACATCCGCTGCCA
GCGCTGCGACCGGCCGATCTGCCCGGACTGCATGCGCGACGCGGCCGTGGGGTTCCAGTGCCCCGAGTGCGTGGCCGAAG
GCCGCAAGAGCACCCGTGCCGGCCGCACCGCCTTCGGCGGGCTGCGGCCGGGCAACGCCGGGACGACGTCGTTCGTCCTG
ATCGGCATCAACGCCTTCGTCTGGCTGATGATCCTGGCCAGCGGGGGCAGCTCGAGCCGGGTGCTGGCCTGGCTGGAGCT
GCGGCCGAACGGGCTGTGCCTCAACGCCGCCGGCGGCTTCGACACCACCCGGGCCGTGTGCTCGGGCCGGGGCGAGTGGC
TGCCCGGTGTGTACGACGGTGCCTACTGGCAGCTGCTCACCAGCACGTTCACGCACGTCCAGCCGTTGCACATCGCGTTC
AACATGTTCGCGCTCTACGTGCTCGGCCCCCAGCTGGAGCTGGCCATCGGCCGGATCCGCTTCCTGGCGCTGTACCTGCT
CTCCGGGCTCACCGGGTCCGCGCTGGTCTACTGGGCGTCCCCGGAGTTCCAGGCCACCGTCGGCGCCTCCGGCGCGATCT
TCGGCCTGATGGGCGCGCTGCTCGTGGTGGCCTACAAGATGCGGGCGAACACCCAGCAGATCCTGATGTGGATCGGCATC
AACTTCGTCTTCACGGTGGTGGTCAGCAACATCTCCTGGCAAGGCCACCTGGGCGGGTTCCTCGGCGGCCTGGTGATCGC
CGCGATCCTCGTCTACGCCCCGCGCGGGCCGAAGCGCCCCTGGTTCCAGGTCTCCGGGCTGGTGCTGGTCGCCGCCCTCA
CCGCCGTCGCGGTCGTCCTCCGCACCGCGGCCCTCGGCTGA

Upstream 100 bases:

>100_bases
GCGATCGCCACCACGGCCACCGGTCCGGGCGACCGCCCGGCCGAGCCGGTCGTGATCGAGACCGTCGAGATCGTCCGCGG
CTGACCCAGGACCACCGAGC

Downstream 100 bases:

>100_bases
CCCGCGCCGCCCTGCGCCCCGCGGACGTCATACGGAGGGTGTCACCTGTGGCTCCGTCCGCATGACGTCCTGGGGCGAGG
GCGCAGGAGTGTGCCGGAGA

Product: rhomboid family protein

Products: NA

Alternate protein names: Intramembrane serine protease [H]

Number of amino acids: Translated: 306; Mature: 305

Protein sequence:

>306_residues
MSEHATPPAGVPTCYRHPGREAHIRCQRCDRPICPDCMRDAAVGFQCPECVAEGRKSTRAGRTAFGGLRPGNAGTTSFVL
IGINAFVWLMILASGGSSSRVLAWLELRPNGLCLNAAGGFDTTRAVCSGRGEWLPGVYDGAYWQLLTSTFTHVQPLHIAF
NMFALYVLGPQLELAIGRIRFLALYLLSGLTGSALVYWASPEFQATVGASGAIFGLMGALLVVAYKMRANTQQILMWIGI
NFVFTVVVSNISWQGHLGGFLGGLVIAAILVYAPRGPKRPWFQVSGLVLVAALTAVAVVLRTAALG

Sequences:

>Translated_306_residues
MSEHATPPAGVPTCYRHPGREAHIRCQRCDRPICPDCMRDAAVGFQCPECVAEGRKSTRAGRTAFGGLRPGNAGTTSFVL
IGINAFVWLMILASGGSSSRVLAWLELRPNGLCLNAAGGFDTTRAVCSGRGEWLPGVYDGAYWQLLTSTFTHVQPLHIAF
NMFALYVLGPQLELAIGRIRFLALYLLSGLTGSALVYWASPEFQATVGASGAIFGLMGALLVVAYKMRANTQQILMWIGI
NFVFTVVVSNISWQGHLGGFLGGLVIAAILVYAPRGPKRPWFQVSGLVLVAALTAVAVVLRTAALG
>Mature_305_residues
SEHATPPAGVPTCYRHPGREAHIRCQRCDRPICPDCMRDAAVGFQCPECVAEGRKSTRAGRTAFGGLRPGNAGTTSFVLI
GINAFVWLMILASGGSSSRVLAWLELRPNGLCLNAAGGFDTTRAVCSGRGEWLPGVYDGAYWQLLTSTFTHVQPLHIAFN
MFALYVLGPQLELAIGRIRFLALYLLSGLTGSALVYWASPEFQATVGASGAIFGLMGALLVVAYKMRANTQQILMWIGIN
FVFTVVVSNISWQGHLGGFLGGLVIAAILVYAPRGPKRPWFQVSGLVLVAALTAVAVVLRTAALG

Specific function: Rhomboid-type serine protease that catalyzes intramembrane proteolysis. Important for normal cell division and sporulation. May act as a glucose exporter [H]

COG id: COG0705

COG function: function code R; Uncharacterized membrane protein (homolog of Drosophila rhomboid)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 2 TPR repeats [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002610
- InterPro:   IPR022764
- InterPro:   IPR001440
- InterPro:   IPR013026
- InterPro:   IPR011990
- InterPro:   IPR019734 [H]

Pfam domain/function: PF01694 Rhomboid; PF00515 TPR_1 [H]

EC number: =3.4.21.105 [H]

Molecular weight: Translated: 32700; Mature: 32568

Theoretical pI: Translated: 9.34; Mature: 9.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEHATPPAGVPTCYRHPGREAHIRCQRCDRPICPDCMRDAAVGFQCPECVAEGRKSTRA
CCCCCCCCCCCCHHHCCCCCHHHHHHHHCCCCCCHHHHHHHHCCCCCHHHHHCCHHHHCC
GRTAFGGLRPGNAGTTSFVLIGINAFVWLMILASGGSSSRVLAWLELRPNGLCLNAAGGF
CCHHCCCCCCCCCCCCEEEEEHHHHHHHHHHHHCCCCCCEEEEEEEECCCCEEEECCCCC
DTTRAVCSGRGEWLPGVYDGAYWQLLTSTFTHVQPLHIAFNMFALYVLGPQLELAIGRIR
CHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHH
FLALYLLSGLTGSALVYWASPEFQATVGASGAIFGLMGALLVVAYKMRANTQQILMWIGI
HHHHHHHHCCCCCEEEEEECCCCEEECCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
NFVFTVVVSNISWQGHLGGFLGGLVIAAILVYAPRGPKRPWFQVSGLVLVAALTAVAVVL
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHH
RTAALG
HHHCCC
>Mature Secondary Structure 
SEHATPPAGVPTCYRHPGREAHIRCQRCDRPICPDCMRDAAVGFQCPECVAEGRKSTRA
CCCCCCCCCCCHHHCCCCCHHHHHHHHCCCCCCHHHHHHHHCCCCCHHHHHCCHHHHCC
GRTAFGGLRPGNAGTTSFVLIGINAFVWLMILASGGSSSRVLAWLELRPNGLCLNAAGGF
CCHHCCCCCCCCCCCCEEEEEHHHHHHHHHHHHCCCCCCEEEEEEEECCCCEEEECCCCC
DTTRAVCSGRGEWLPGVYDGAYWQLLTSTFTHVQPLHIAFNMFALYVLGPQLELAIGRIR
CHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHH
FLALYLLSGLTGSALVYWASPEFQATVGASGAIFGLMGALLVVAYKMRANTQQILMWIGI
HHHHHHHHCCCCCEEEEEECCCCEEECCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
NFVFTVVVSNISWQGHLGGFLGGLVIAAILVYAPRGPKRPWFQVSGLVLVAALTAVAVVL
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHH
RTAALG
HHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]