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The map label for this gene is gapB [H]

Identifier: 119387170

GI number: 119387170

Start: 1679499

End: 1680500

Strand: Direct

Name: gapB [H]

Synonym: Pden_4465

Alternate gene names: 119387170

Gene position: 1679499-1680500 (Clockwise)

Preceding gene: 119387169

Following gene: 119387172

Centisome position: 97.08

GC content: 63.97

Gene sequence:

>1002_bases
ATGGCTGTAAAGGTAGCGATCAACGGCTTTGGCCGGATCGGTCGGAACGTGCTGCGCGCGATCATCGAATCGGGACGCAA
TGATATCGAGGTCGTGGCGATCAACGACCTCGGCCCGGTCGAGACCAATGCGCATCTGCTGCGCTACGATTCGGTCCACG
GCCGCTTCCCCGCCGAGGTCAAGGTGACCGACGACTCGATCGATGTCGGCCGCGGCCCGATCAAGGTCACCGCGATCCGC
AACCCGGCCGAACTGCCCTGGGGCGACATCGACGTGATCATGGAATGCACCGGCATCTTCGCCTCCAAGGAAAAGGTGCA
GCCGCACCTGTCGACCGGAGCCAAGCGCGTGCTGATCTCGGCCCCCGGCGACAATGCCGACAAGACCATCGTCTATGGCG
TGAACCACGACACGCTGACCAAGGACGACATCGTCGTCTCGAACGCCAGCTGCACCACCAATTGCCTGTCGCCCGTCGCC
AAGGTGCTCAACGACAGCATCGGCATCGCCCGCGGCTTCATGACCACGATCCACAGCTATACCGGCGACCAGCCGACGCT
GGACACCATGCACAAGGATCTGTATCGCGCCCGCGCCGCGGCGCTATCGATGATCCCGACCTCGACCGGCGCGGCCAAGG
CCGTGGGCCTGGTGCTGCCGGAGCTCAAGGGCAGGCTGGACGGCGTCGCGATCCGCGTGCCGACCCCGAACGTCTCGGTC
GTGGACCTGGTCTTCGAAGCCGCCCGCGACACCTCGGTCGAAGAGATCAACGAAGCGATCCGCACCGCCGCCAACGGTTC
GCTGAAGGGCATCCTAGGCTATACCGACGAGCCGCTGGTTTCCTCGGACTTCAACCACGATTCGCACAGCTCGGTCTTCC
ACATGGACCAGACCAAGGTGATGGAGGGCCGGCTTTGCCGCATCCTGACCTGGTATGACAACGAGTGGGGCTTCTCGAAC
CGCATGTCCGACACCGCGGTCGCCATGGGCAAGCTGATCTGA

Upstream 100 bases:

>100_bases
TTTGGCCGAGTTTCCGCCCCAAGGGGTTTCAGGCATTTGCATTCCCCCGGCGATGCGGGCTATTTGCAGCGCGGAACATC
ATCAGCGGCGGAGGAAACCT

Downstream 100 bases:

>100_bases
GCCCCGTGACTCGGACGTGAAAAGCGAAACGCGCCCCCGGTAAACGGGGGCGCGTTTTCACATCCGGCCCAGGGCCGCGG
CAGGCGCCTTCAGTCCTTGC

Product: glyceraldehyde-3-phosphate dehydrogenase, type I

Products: NA

Alternate protein names: GAPDH [H]

Number of amino acids: Translated: 333; Mature: 332

Protein sequence:

>333_residues
MAVKVAINGFGRIGRNVLRAIIESGRNDIEVVAINDLGPVETNAHLLRYDSVHGRFPAEVKVTDDSIDVGRGPIKVTAIR
NPAELPWGDIDVIMECTGIFASKEKVQPHLSTGAKRVLISAPGDNADKTIVYGVNHDTLTKDDIVVSNASCTTNCLSPVA
KVLNDSIGIARGFMTTIHSYTGDQPTLDTMHKDLYRARAAALSMIPTSTGAAKAVGLVLPELKGRLDGVAIRVPTPNVSV
VDLVFEAARDTSVEEINEAIRTAANGSLKGILGYTDEPLVSSDFNHDSHSSVFHMDQTKVMEGRLCRILTWYDNEWGFSN
RMSDTAVAMGKLI

Sequences:

>Translated_333_residues
MAVKVAINGFGRIGRNVLRAIIESGRNDIEVVAINDLGPVETNAHLLRYDSVHGRFPAEVKVTDDSIDVGRGPIKVTAIR
NPAELPWGDIDVIMECTGIFASKEKVQPHLSTGAKRVLISAPGDNADKTIVYGVNHDTLTKDDIVVSNASCTTNCLSPVA
KVLNDSIGIARGFMTTIHSYTGDQPTLDTMHKDLYRARAAALSMIPTSTGAAKAVGLVLPELKGRLDGVAIRVPTPNVSV
VDLVFEAARDTSVEEINEAIRTAANGSLKGILGYTDEPLVSSDFNHDSHSSVFHMDQTKVMEGRLCRILTWYDNEWGFSN
RMSDTAVAMGKLI
>Mature_332_residues
AVKVAINGFGRIGRNVLRAIIESGRNDIEVVAINDLGPVETNAHLLRYDSVHGRFPAEVKVTDDSIDVGRGPIKVTAIRN
PAELPWGDIDVIMECTGIFASKEKVQPHLSTGAKRVLISAPGDNADKTIVYGVNHDTLTKDDIVVSNASCTTNCLSPVAK
VLNDSIGIARGFMTTIHSYTGDQPTLDTMHKDLYRARAAALSMIPTSTGAAKAVGLVLPELKGRLDGVAIRVPTPNVSVV
DLVFEAARDTSVEEINEAIRTAANGSLKGILGYTDEPLVSSDFNHDSHSSVFHMDQTKVMEGRLCRILTWYDNEWGFSNR
MSDTAVAMGKLI

Specific function: Could Play A Role In Pyridoxal 5'-Phosphate Synthesis. [C]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7669492, Length=331, Percent_Identity=45.9214501510574, Blast_Score=296, Evalue=1e-80,
Organism=Homo sapiens, GI7657116, Length=326, Percent_Identity=44.7852760736196, Blast_Score=276, Evalue=2e-74,
Organism=Escherichia coli, GI1789295, Length=336, Percent_Identity=48.5119047619048, Blast_Score=327, Evalue=8e-91,
Organism=Escherichia coli, GI1788079, Length=327, Percent_Identity=48.9296636085627, Blast_Score=313, Evalue=1e-86,
Organism=Caenorhabditis elegans, GI17534677, Length=330, Percent_Identity=46.969696969697, Blast_Score=294, Evalue=3e-80,
Organism=Caenorhabditis elegans, GI17534679, Length=330, Percent_Identity=46.6666666666667, Blast_Score=294, Evalue=5e-80,
Organism=Caenorhabditis elegans, GI32566163, Length=330, Percent_Identity=46.969696969697, Blast_Score=290, Evalue=6e-79,
Organism=Caenorhabditis elegans, GI17568413, Length=330, Percent_Identity=46.969696969697, Blast_Score=290, Evalue=7e-79,
Organism=Saccharomyces cerevisiae, GI6321631, Length=328, Percent_Identity=49.390243902439, Blast_Score=310, Evalue=3e-85,
Organism=Saccharomyces cerevisiae, GI6322409, Length=328, Percent_Identity=48.1707317073171, Blast_Score=308, Evalue=1e-84,
Organism=Saccharomyces cerevisiae, GI6322468, Length=328, Percent_Identity=48.4756097560976, Blast_Score=304, Evalue=1e-83,
Organism=Drosophila melanogaster, GI17933600, Length=325, Percent_Identity=49.5384615384615, Blast_Score=295, Evalue=2e-80,
Organism=Drosophila melanogaster, GI18110149, Length=325, Percent_Identity=49.5384615384615, Blast_Score=295, Evalue=2e-80,
Organism=Drosophila melanogaster, GI85725000, Length=325, Percent_Identity=47.6923076923077, Blast_Score=288, Evalue=4e-78,
Organism=Drosophila melanogaster, GI22023983, Length=325, Percent_Identity=47.6923076923077, Blast_Score=288, Evalue=4e-78,
Organism=Drosophila melanogaster, GI19922412, Length=325, Percent_Identity=42.1538461538462, Blast_Score=260, Evalue=8e-70,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006424
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.12 [H]

Molecular weight: Translated: 35925; Mature: 35794

Theoretical pI: Translated: 6.04; Mature: 6.04

Prosite motif: PS00071 GAPDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVKVAINGFGRIGRNVLRAIIESGRNDIEVVAINDLGPVETNAHLLRYDSVHGRFPAEV
CEEEEEECCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCEEEEECCCCCCCCCEE
KVTDDSIDVGRGPIKVTAIRNPAELPWGDIDVIMECTGIFASKEKVQPHLSTGAKRVLIS
EEECCCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHCHHHCCCCCCCCCEEEEEE
APGDNADKTIVYGVNHDTLTKDDIVVSNASCTTNCLSPVAKVLNDSIGIARGFMTTIHSY
CCCCCCCCEEEEECCCCCCCCCCEEEECCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHC
TGDQPTLDTMHKDLYRARAAALSMIPTSTGAAKAVGLVLPELKGRLDGVAIRVPTPNVSV
CCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCEEEEECCCCCHH
VDLVFEAARDTSVEEINEAIRTAANGSLKGILGYTDEPLVSSDFNHDSHSSVFHMDQTKV
HHHHHHHHCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCCEEECCHHHH
MEGRLCRILTWYDNEWGFSNRMSDTAVAMGKLI
HCCCEEEEEEEECCCCCCCCCCCHHHHHHHCCC
>Mature Secondary Structure 
AVKVAINGFGRIGRNVLRAIIESGRNDIEVVAINDLGPVETNAHLLRYDSVHGRFPAEV
EEEEEECCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCEEEEECCCCCCCCCEE
KVTDDSIDVGRGPIKVTAIRNPAELPWGDIDVIMECTGIFASKEKVQPHLSTGAKRVLIS
EEECCCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHCHHHCCCCCCCCCEEEEEE
APGDNADKTIVYGVNHDTLTKDDIVVSNASCTTNCLSPVAKVLNDSIGIARGFMTTIHSY
CCCCCCCCEEEEECCCCCCCCCCEEEECCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHC
TGDQPTLDTMHKDLYRARAAALSMIPTSTGAAKAVGLVLPELKGRLDGVAIRVPTPNVSV
CCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCEEEEECCCCCHH
VDLVFEAARDTSVEEINEAIRTAANGSLKGILGYTDEPLVSSDFNHDSHSSVFHMDQTKV
HHHHHHHHCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCCEEECCHHHH
MEGRLCRILTWYDNEWGFSNRMSDTAVAMGKLI
HCCCEEEEEEEECCCCCCCCCCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1939098 [H]