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The map label for this gene is btuB [H]

Identifier: 119387087

GI number: 119387087

Start: 1575068

End: 1576975

Strand: Direct

Name: btuB [H]

Synonym: Pden_4382

Alternate gene names: 119387087

Gene position: 1575068-1576975 (Clockwise)

Preceding gene: 119387085

Following gene: 119387088

Centisome position: 91.04

GC content: 67.19

Gene sequence:

>1908_bases
ATGTTGTTCAGAACCCCGGCTTCCCTGCTGGCCGCCACCGCCCTGCTCCTGCCCGCCGCCGCAACGGGGCAGGAAGGCCA
GGCCCCCGTCATGCTTGACCCGGTGGTCCTGTCGGGCGGGCTGTCGCCCGTCGCCGAAAGCGCCTATGGCCGGGCCTACA
GCATCCTGACCGCCGAGGATTTGCGGCAGCGCGGCTTCGTCACCGTCCAGGACGCGCTGCGCGACCTGCCCGGGCTTGCC
GTGACCTCGACCGGCGAGACCCTGACCATGGTCCGCATCCGCGGGGGCGAAGCCAATCATGTGCTGGTGCTGATCGACGG
GGTCGAGGCCAACTCTCCCGGCAACGGAGACTATGTCTTCAGCGGTCTTCTGACCGAGGATGTCGAGCGCATCGAGGTGC
TGCGCGGCCCGCAATCGACCATCTACGGCGCCAATGCCGCCGCCGGGGTGATCGCGATCACCACCCGCCGCGCCTCTGTC
CCGGGGCTGAGCTATGGCGGCGGGATCGAGATCGGCGGGCTGGGCACCCGCGCCGCCAGCGCCCATCTCCGCGCCATGGG
CGAGCGCGGCCAGATCAGCTTCTCGGCGGCGACACGCCGCACCGATGGCGAGGACGCCTCGCGCACGCCGGGCGGCGATA
CCGAGTTCAACAACCGCGAGACGCTGACCCTCGGTGGCTCCTACGACATCGCCGAGGCCGTGACCGCCGGCTTCACCCTG
CGCCGGACCTGGCAGGAATACGGCTACGACCGGGCGATCGACCCGGTGGATTCCCCCGACGACCATGTGATCGACACACC
GCACACCGCCGACCGCAACGAAACCTATGGCTCGCTCTGGATCGAGGCCGAGGCGCTGGGGGGCAGGCTGCTGAACCGCT
TCGCCGTCTCGGGCTCCAACCAGGCCACGGACCATTTCAACGACGGCGTGCCGGATTACGACGACGCCTCGCGGCTGCGG
GATTTCAGGTATACCGGCACATGGGCGCTGGACGGCGGCAATGCCCGCAATTCCGCGCAAAAGCTCAATTTCGCGGTGCA
GAAGAAGCGCGAGATCTATGAGAGCTCCTATGCACCGGGCGGCCGGTATGAGCGCGACACGAAATCGCTTGCGCTGGAAT
ATCAGGGCCAGTTCGACAACGGGATCGGCATCCAGGCCGGCCTGCGGCGCGATTTCAACGACGATTTCCGCAACGCGACC
ACCTGGAACATCGCTGGCGCATGGCAATTGCCCGATCGCGACCTGCGCCTGCGCGCGGCCGCCGGCAAGGCCATCGTCAA
TCCCACCATGTTCGAGCTTTATGGCTATGCGCCGGGCAGCTATAGCGGCAACCCGGACCTGACGCCGGAAACCAGCCGCA
GCTATGAAATCGGCGCCGACTGGAGTTTCGCAGCGGGACGGGCTGCGCTGGGGGCGACCCTGTTCACCAGCAAGGTCGAG
GACATGATCGTCGGGGCCGGCACCACCTCGCAAAACATCGCCGGCACCAGCACGCGCAAGGGGTTCGAGGCCGATCTGCA
CTATGAAGCCACCGATTGGCTGCGGCTGGGCGCGACCTATACCTATACCGACGCCCGCACGGAAGACGACGATCCCATCC
CGCGCCAGCCGCGCCACCAGCTTGGGCTGCGCGCCACGGGCGATTTTGCCGGGGGTCGCGGCTCGGCCACGGCCGATCTG
CGCTATGTCGCGGGCAATTACGACGAGGAATGGTTCAGAAGCTGGACCCCGCCCACCACCGAACTGCCCGATTTCGTGAC
CGTGAACCTGGCCGCGCAATACGACCTGACCGAAAACCTGCGCCTGACCGGCCGCGTGGTGAACCTGTTCGACAGGGATT
ATTCCGAGGCCTGGGGCTATTACGGCCAGGGCCGCACCTTCTATGCCGGCCTGACGGCGCAATGGTAG

Upstream 100 bases:

>100_bases
AGAGGTGACAGTCGCCATCCCGCGGCCGGGCTGCCCTTGGCCTTTCCGCAGGACAGTTCTGCAAATCGCGGGCCGGATCC
CGCGCTGGAAAGGCTTTGGA

Downstream 100 bases:

>100_bases
GACGGCTTTGCCTTGCCGCCTGCCTTCTGGCCGGCCTGATCCTGCCCGCCGCGGCCGAGCCGCCGCGCCGGGTGCTGTCC
GTGAACCTGTGCACCGACCA

Product: TonB-dependent receptor

Products: NA

Alternate protein names: Cobalamin receptor; Outer membrane cobalamin translocator [H]

Number of amino acids: Translated: 635; Mature: 635

Protein sequence:

>635_residues
MLFRTPASLLAATALLLPAAATGQEGQAPVMLDPVVLSGGLSPVAESAYGRAYSILTAEDLRQRGFVTVQDALRDLPGLA
VTSTGETLTMVRIRGGEANHVLVLIDGVEANSPGNGDYVFSGLLTEDVERIEVLRGPQSTIYGANAAAGVIAITTRRASV
PGLSYGGGIEIGGLGTRAASAHLRAMGERGQISFSAATRRTDGEDASRTPGGDTEFNNRETLTLGGSYDIAEAVTAGFTL
RRTWQEYGYDRAIDPVDSPDDHVIDTPHTADRNETYGSLWIEAEALGGRLLNRFAVSGSNQATDHFNDGVPDYDDASRLR
DFRYTGTWALDGGNARNSAQKLNFAVQKKREIYESSYAPGGRYERDTKSLALEYQGQFDNGIGIQAGLRRDFNDDFRNAT
TWNIAGAWQLPDRDLRLRAAAGKAIVNPTMFELYGYAPGSYSGNPDLTPETSRSYEIGADWSFAAGRAALGATLFTSKVE
DMIVGAGTTSQNIAGTSTRKGFEADLHYEATDWLRLGATYTYTDARTEDDDPIPRQPRHQLGLRATGDFAGGRGSATADL
RYVAGNYDEEWFRSWTPPTTELPDFVTVNLAAQYDLTENLRLTGRVVNLFDRDYSEAWGYYGQGRTFYAGLTAQW

Sequences:

>Translated_635_residues
MLFRTPASLLAATALLLPAAATGQEGQAPVMLDPVVLSGGLSPVAESAYGRAYSILTAEDLRQRGFVTVQDALRDLPGLA
VTSTGETLTMVRIRGGEANHVLVLIDGVEANSPGNGDYVFSGLLTEDVERIEVLRGPQSTIYGANAAAGVIAITTRRASV
PGLSYGGGIEIGGLGTRAASAHLRAMGERGQISFSAATRRTDGEDASRTPGGDTEFNNRETLTLGGSYDIAEAVTAGFTL
RRTWQEYGYDRAIDPVDSPDDHVIDTPHTADRNETYGSLWIEAEALGGRLLNRFAVSGSNQATDHFNDGVPDYDDASRLR
DFRYTGTWALDGGNARNSAQKLNFAVQKKREIYESSYAPGGRYERDTKSLALEYQGQFDNGIGIQAGLRRDFNDDFRNAT
TWNIAGAWQLPDRDLRLRAAAGKAIVNPTMFELYGYAPGSYSGNPDLTPETSRSYEIGADWSFAAGRAALGATLFTSKVE
DMIVGAGTTSQNIAGTSTRKGFEADLHYEATDWLRLGATYTYTDARTEDDDPIPRQPRHQLGLRATGDFAGGRGSATADL
RYVAGNYDEEWFRSWTPPTTELPDFVTVNLAAQYDLTENLRLTGRVVNLFDRDYSEAWGYYGQGRTFYAGLTAQW
>Mature_635_residues
MLFRTPASLLAATALLLPAAATGQEGQAPVMLDPVVLSGGLSPVAESAYGRAYSILTAEDLRQRGFVTVQDALRDLPGLA
VTSTGETLTMVRIRGGEANHVLVLIDGVEANSPGNGDYVFSGLLTEDVERIEVLRGPQSTIYGANAAAGVIAITTRRASV
PGLSYGGGIEIGGLGTRAASAHLRAMGERGQISFSAATRRTDGEDASRTPGGDTEFNNRETLTLGGSYDIAEAVTAGFTL
RRTWQEYGYDRAIDPVDSPDDHVIDTPHTADRNETYGSLWIEAEALGGRLLNRFAVSGSNQATDHFNDGVPDYDDASRLR
DFRYTGTWALDGGNARNSAQKLNFAVQKKREIYESSYAPGGRYERDTKSLALEYQGQFDNGIGIQAGLRRDFNDDFRNAT
TWNIAGAWQLPDRDLRLRAAAGKAIVNPTMFELYGYAPGSYSGNPDLTPETSRSYEIGADWSFAAGRAALGATLFTSKVE
DMIVGAGTTSQNIAGTSTRKGFEADLHYEATDWLRLGATYTYTDARTEDDDPIPRQPRHQLGLRATGDFAGGRGSATADL
RYVAGNYDEEWFRSWTPPTTELPDFVTVNLAAQYDLTENLRLTGRVVNLFDRDYSEAWGYYGQGRTFYAGLTAQW

Specific function: Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB [H]

COG id: COG4206

COG function: function code H; Outer membrane cobalamin receptor protein

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the TonB-dependent receptor family. BtuB (TC 1.B.14.3.1) subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790405, Length=603, Percent_Identity=26.6998341625207, Blast_Score=141, Evalue=1e-34,
Organism=Escherichia coli, GI1788478, Length=153, Percent_Identity=30.0653594771242, Blast_Score=86, Evalue=6e-18,

Paralogues:

None

Copy number: 100 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010101
- InterPro:   IPR010916
- InterPro:   IPR010917 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 68835; Mature: 68835

Theoretical pI: Translated: 4.58; Mature: 4.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLFRTPASLLAATALLLPAAATGQEGQAPVMLDPVVLSGGLSPVAESAYGRAYSILTAED
CCCCCHHHHHHHHHHHHCCCCCCCCCCCCEEECCEEECCCCCHHHHHHCCCEEEEEEHHH
LRQRGFVTVQDALRDLPGLAVTSTGETLTMVRIRGGEANHVLVLIDGVEANSPGNGDYVF
HHHCCCEEHHHHHHHCCCEEEECCCCEEEEEEEECCCCCEEEEEEECCCCCCCCCCCEEE
SGLLTEDVERIEVLRGPQSTIYGANAAAGVIAITTRRASVPGLSYGGGIEIGGLGTRAAS
ECHHHHHHHHHHHHCCCCHHEECCCCCCCEEEEEEECCCCCCCCCCCCEEECCCCCHHHH
AHLRAMGERGQISFSAATRRTDGEDASRTPGGDTEFNNRETLTLGGSYDIAEAVTAGFTL
HHHHHCCCCCCEEEEHHCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHCHHH
RRTWQEYGYDRAIDPVDSPDDHVIDTPHTADRNETYGSLWIEAEALGGRLLNRFAVSGSN
HHHHHHCCCCCCCCCCCCCCCCEECCCCCCCCCCCCEEEEEEEHHHHHHHHHHHHCCCCC
QATDHFNDGVPDYDDASRLRDFRYTGTWALDGGNARNSAQKLNFAVQKKREIYESSYAPG
CCCCCCCCCCCCCCCHHHHHHEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCC
GRYERDTKSLALEYQGQFDNGIGIQAGLRRDFNDDFRNATTWNIAGAWQLPDRDLRLRAA
CCCCCCCCEEEEEECCCCCCCCCCHHCCCCCCCHHHCCCEEEEEEEEEECCCCCEEEEEE
AGKAIVNPTMFELYGYAPGSYSGNPDLTPETSRSYEIGADWSFAAGRAALGATLFTSKVE
CCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCEEECCCCCCCCCHHHHHHHHHHHHHH
DMIVGAGTTSQNIAGTSTRKGFEADLHYEATDWLRLGATYTYTDARTEDDDPIPRQPRHQ
HHEEECCCCCCCCCCCCCCCCCCCEEEECCCCCEEECCEEEECCCCCCCCCCCCCCCHHH
LGLRATGDFAGGRGSATADLRYVAGNYDEEWFRSWTPPTTELPDFVTVNLAAQYDLTENL
CCCEECCCCCCCCCCCCEEEEEEECCCCHHHHHCCCCCCCCCCCEEEEEEEEEECCCCCC
RLTGRVVNLFDRDYSEAWGYYGQGRTFYAGLTAQW
EEEEEEEEHHHCCHHHHCCCCCCCEEEEEEEEECC
>Mature Secondary Structure
MLFRTPASLLAATALLLPAAATGQEGQAPVMLDPVVLSGGLSPVAESAYGRAYSILTAED
CCCCCHHHHHHHHHHHHCCCCCCCCCCCCEEECCEEECCCCCHHHHHHCCCEEEEEEHHH
LRQRGFVTVQDALRDLPGLAVTSTGETLTMVRIRGGEANHVLVLIDGVEANSPGNGDYVF
HHHCCCEEHHHHHHHCCCEEEECCCCEEEEEEEECCCCCEEEEEEECCCCCCCCCCCEEE
SGLLTEDVERIEVLRGPQSTIYGANAAAGVIAITTRRASVPGLSYGGGIEIGGLGTRAAS
ECHHHHHHHHHHHHCCCCHHEECCCCCCCEEEEEEECCCCCCCCCCCCEEECCCCCHHHH
AHLRAMGERGQISFSAATRRTDGEDASRTPGGDTEFNNRETLTLGGSYDIAEAVTAGFTL
HHHHHCCCCCCEEEEHHCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHCHHH
RRTWQEYGYDRAIDPVDSPDDHVIDTPHTADRNETYGSLWIEAEALGGRLLNRFAVSGSN
HHHHHHCCCCCCCCCCCCCCCCEECCCCCCCCCCCCEEEEEEEHHHHHHHHHHHHCCCCC
QATDHFNDGVPDYDDASRLRDFRYTGTWALDGGNARNSAQKLNFAVQKKREIYESSYAPG
CCCCCCCCCCCCCCCHHHHHHEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCC
GRYERDTKSLALEYQGQFDNGIGIQAGLRRDFNDDFRNATTWNIAGAWQLPDRDLRLRAA
CCCCCCCCEEEEEECCCCCCCCCCHHCCCCCCCHHHCCCEEEEEEEEEECCCCCEEEEEE
AGKAIVNPTMFELYGYAPGSYSGNPDLTPETSRSYEIGADWSFAAGRAALGATLFTSKVE
CCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCEEECCCCCCCCCHHHHHHHHHHHHHH
DMIVGAGTTSQNIAGTSTRKGFEADLHYEATDWLRLGATYTYTDARTEDDDPIPRQPRHQ
HHEEECCCCCCCCCCCCCCCCCCCEEEECCCCCEEECCEEEECCCCCCCCCCCCCCCHHH
LGLRATGDFAGGRGSATADLRYVAGNYDEEWFRSWTPPTTELPDFVTVNLAAQYDLTENL
CCCEECCCCCCCCCCCCEEEEEEECCCCHHHHHCCCCCCCCCCCEEEEEEEEEECCCCCC
RLTGRVVNLFDRDYSEAWGYYGQGRTFYAGLTAQW
EEEEEEEEHHHCCHHHHCCCCCCCEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11598060 [H]