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The map label for this gene is yfnA [H]

Identifier: 119387039

GI number: 119387039

Start: 1513676

End: 1515139

Strand: Direct

Name: yfnA [H]

Synonym: Pden_4334

Alternate gene names: 119387039

Gene position: 1513676-1515139 (Clockwise)

Preceding gene: 119387029

Following gene: 119387044

Centisome position: 87.49

GC content: 66.46

Gene sequence:

>1464_bases
ATGACGACCGCAACAGGGACCAGGACGGAACCGGAGCAGCACACGCTCAAGCGGGTCATCGGACCCAAGCTGCTTTTGCT
TTTCATCGTGGGCGACATTCTCGGCACCGGGGTCTATGCCCTGACCGGCACCGTGGCGGGCGAGGTGGGCGGCGCGGCCT
GGGCGCCGTTCCTGGTCGCCTTTCTCGTCGCCACCATCACCGCGCTGTCCTATCTGGAACTGGTCACGCGCTATCCGCAG
GCGGCGGGTGCGGCGCTTTATGCCCATCGCGCCTTCGGCATCCATTTCCTGACCTTCCTCGTGGCCTTCACCGTCATGTG
CTCGGGGATCACTTCGGCCTCGACGGCGTCGAACGCCTTCGCGGGCTTCATGAACGACGGCTTCGGCCTGGGCTTTCGCA
AGGACGGCAGCGGCATCCTGATCATCGCGCTGGGGTTCATGGCGCTGGTCGCCGCGATCAACTTCCGCGGCGTCGGCGAA
AGCGTCAAGGCCAACGTGGTGCTGACCTGCGTCGAGCTTTCGGGCCTGCTGATGATCATCTTCATCGGCTTTTACGCCAT
GGGCCAGGGCCGGGCGGATTTCAGCGAGGTTATGATCTTCCGCTCGCCCGACGAAAAGGGCGCCTTCCTGGCGCTGACGG
CCGCGACGGCGCTGGCCTTCTTCGCCATGGTCGGTTTCGAGGATTCGGTGAACATGGCCGAGGAGGTCACGGACCCGGTC
CGCATCTTTCCCCGCATCATGCTGACCGGGCTGGGCATTACCGGGGTGATCTATGTGCTGGTGGCGATCTGCGCCGTGGC
GCTGGTGCCGGTGGGCGACCTGTCGGACCCCGACAAGGGCTCGGCGCTGACGCAGGTGGTGCGGGCGGGGGCGCCGAACT
TCCCCTTCGACAAGATCTTTCCCTTCATCGGCATGTTCGCGGTGGCGAACTCGGCGCTGATCAACATGCTGATGGCCAGC
CGGCTGCTTTACGGCCTGGCGCGGCAGGGGGTGCTGCCGCACGGGCTGGGGCTTGTGCATCGCGAACGGCGCACGCCCTG
GGTCGCGATCATCTTCACCACGCTGCTGGCCTTCGGGCTGATCTATTTCGTCGTCACCCGCTCGGACCTGCCGGCGGTCA
GCCTGCTGGGCGGCACCACGGCCCTGCTGCTGCTGTGCGTCTTTACCGTGGTCAACATCTCGCTGCTGGTGCTGCGCAAG
CGCCCGGTCGAGCGTCAGCATTTCAAGGCGCCGGGCTGGGTGCCCTGGGTCGGCGCGGCGACCTGCGCCTTTCTGGCCGG
ACCCTGGGCGCGCTCGGCCGCGCAGATGGACCAATACAAGGTGGCGGGCTGGCTGATCGGGATCGGCATCGTGCTGTGGG
CCGCGACCTATCTGTGGAACCGCGCGACACGGCACCATGTGCCGGGCGGGCTGGAGCATGTCGAGGATCTGGCCGAACAT
CACGGCGATTCGACCCGGAACTGA

Upstream 100 bases:

>100_bases
TGGGAAACAGGGCCATCGCATGCAACCGATGCGGGTTGCCCGGAAAGCGTGATGGGAGCACCCTTTCGGACACCAGCCCG
GAAACCAGGGGGGATCACAA

Downstream 100 bases:

>100_bases
TCTCCCGCGGGCCGGCGGCACCGTGGCCTAGTTCTCGCGGAAGGCGCGCGAGAGGCTGTCCTCGATCGGCTTGATCAGGT
ATTGCGCAAAGGTTCTGGCG

Product: amino acid permease-associated region

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 487; Mature: 486

Protein sequence:

>487_residues
MTTATGTRTEPEQHTLKRVIGPKLLLLFIVGDILGTGVYALTGTVAGEVGGAAWAPFLVAFLVATITALSYLELVTRYPQ
AAGAALYAHRAFGIHFLTFLVAFTVMCSGITSASTASNAFAGFMNDGFGLGFRKDGSGILIIALGFMALVAAINFRGVGE
SVKANVVLTCVELSGLLMIIFIGFYAMGQGRADFSEVMIFRSPDEKGAFLALTAATALAFFAMVGFEDSVNMAEEVTDPV
RIFPRIMLTGLGITGVIYVLVAICAVALVPVGDLSDPDKGSALTQVVRAGAPNFPFDKIFPFIGMFAVANSALINMLMAS
RLLYGLARQGVLPHGLGLVHRERRTPWVAIIFTTLLAFGLIYFVVTRSDLPAVSLLGGTTALLLLCVFTVVNISLLVLRK
RPVERQHFKAPGWVPWVGAATCAFLAGPWARSAAQMDQYKVAGWLIGIGIVLWAATYLWNRATRHHVPGGLEHVEDLAEH
HGDSTRN

Sequences:

>Translated_487_residues
MTTATGTRTEPEQHTLKRVIGPKLLLLFIVGDILGTGVYALTGTVAGEVGGAAWAPFLVAFLVATITALSYLELVTRYPQ
AAGAALYAHRAFGIHFLTFLVAFTVMCSGITSASTASNAFAGFMNDGFGLGFRKDGSGILIIALGFMALVAAINFRGVGE
SVKANVVLTCVELSGLLMIIFIGFYAMGQGRADFSEVMIFRSPDEKGAFLALTAATALAFFAMVGFEDSVNMAEEVTDPV
RIFPRIMLTGLGITGVIYVLVAICAVALVPVGDLSDPDKGSALTQVVRAGAPNFPFDKIFPFIGMFAVANSALINMLMAS
RLLYGLARQGVLPHGLGLVHRERRTPWVAIIFTTLLAFGLIYFVVTRSDLPAVSLLGGTTALLLLCVFTVVNISLLVLRK
RPVERQHFKAPGWVPWVGAATCAFLAGPWARSAAQMDQYKVAGWLIGIGIVLWAATYLWNRATRHHVPGGLEHVEDLAEH
HGDSTRN
>Mature_486_residues
TTATGTRTEPEQHTLKRVIGPKLLLLFIVGDILGTGVYALTGTVAGEVGGAAWAPFLVAFLVATITALSYLELVTRYPQA
AGAALYAHRAFGIHFLTFLVAFTVMCSGITSASTASNAFAGFMNDGFGLGFRKDGSGILIIALGFMALVAAINFRGVGES
VKANVVLTCVELSGLLMIIFIGFYAMGQGRADFSEVMIFRSPDEKGAFLALTAATALAFFAMVGFEDSVNMAEEVTDPVR
IFPRIMLTGLGITGVIYVLVAICAVALVPVGDLSDPDKGSALTQVVRAGAPNFPFDKIFPFIGMFAVANSALINMLMASR
LLYGLARQGVLPHGLGLVHRERRTPWVAIIFTTLLAFGLIYFVVTRSDLPAVSLLGGTTALLLLCVFTVVNISLLVLRKR
PVERQHFKAPGWVPWVGAATCAFLAGPWARSAAQMDQYKVAGWLIGIGIVLWAATYLWNRATRHHVPGGLEHVEDLAEHH
GDSTRN

Specific function: Probable Amino-Acid Or Metabolite Transport Protein. [C]

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Homo sapiens, GI258614003, Length=423, Percent_Identity=24.5862884160757, Blast_Score=80, Evalue=6e-15,
Organism=Homo sapiens, GI258614005, Length=423, Percent_Identity=24.5862884160757, Blast_Score=80, Evalue=6e-15,
Organism=Homo sapiens, GI258645169, Length=423, Percent_Identity=25.531914893617, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI110347453, Length=353, Percent_Identity=26.628895184136, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI4507047, Length=437, Percent_Identity=23.3409610983982, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI186910308, Length=371, Percent_Identity=26.4150943396226, Blast_Score=73, Evalue=5e-13,
Organism=Homo sapiens, GI186910306, Length=371, Percent_Identity=26.4150943396226, Blast_Score=73, Evalue=5e-13,
Organism=Homo sapiens, GI186910304, Length=371, Percent_Identity=26.4150943396226, Blast_Score=73, Evalue=5e-13,
Organism=Homo sapiens, GI114326544, Length=436, Percent_Identity=22.9357798165138, Blast_Score=73, Evalue=6e-13,
Organism=Homo sapiens, GI114326550, Length=436, Percent_Identity=22.9357798165138, Blast_Score=73, Evalue=6e-13,
Organism=Homo sapiens, GI181337167, Length=398, Percent_Identity=26.6331658291457, Blast_Score=70, Evalue=6e-12,
Organism=Homo sapiens, GI115648063, Length=372, Percent_Identity=25, Blast_Score=67, Evalue=4e-11,
Organism=Homo sapiens, GI115648022, Length=372, Percent_Identity=25, Blast_Score=67, Evalue=4e-11,
Organism=Escherichia coli, GI87081869, Length=397, Percent_Identity=24.6851385390428, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1786694, Length=336, Percent_Identity=24.4047619047619, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI87082023, Length=389, Percent_Identity=27.5064267352185, Blast_Score=70, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17533459, Length=412, Percent_Identity=25.9708737864078, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17532491, Length=424, Percent_Identity=23.3490566037736, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17531343, Length=374, Percent_Identity=24.331550802139, Blast_Score=69, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24667468, Length=430, Percent_Identity=24.6511627906977, Blast_Score=108, Evalue=8e-24,
Organism=Drosophila melanogaster, GI45550968, Length=471, Percent_Identity=26.963906581741, Blast_Score=88, Evalue=2e-17,
Organism=Drosophila melanogaster, GI19921172, Length=471, Percent_Identity=26.963906581741, Blast_Score=88, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24668806, Length=441, Percent_Identity=24.2630385487528, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI21356285, Length=441, Percent_Identity=24.2630385487528, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24668802, Length=441, Percent_Identity=24.2630385487528, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI221512776, Length=423, Percent_Identity=22.2222222222222, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24666159, Length=423, Percent_Identity=22.2222222222222, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI161077963, Length=408, Percent_Identity=24.5098039215686, Blast_Score=72, Evalue=9e-13,
Organism=Drosophila melanogaster, GI21357367, Length=436, Percent_Identity=25.2293577981651, Blast_Score=70, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR015606 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 52030; Mature: 51899

Theoretical pI: Translated: 8.47; Mature: 8.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTATGTRTEPEQHTLKRVIGPKLLLLFIVGDILGTGVYALTGTVAGEVGGAAWAPFLVA
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHH
FLVATITALSYLELVTRYPQAAGAALYAHRAFGIHFLTFLVAFTVMCSGITSASTASNAF
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
AGFMNDGFGLGFRKDGSGILIIALGFMALVAAINFRGVGESVKANVVLTCVELSGLLMII
HHHHCCCCCCCEEECCCCEEHHHHHHHHHHHHHHCCCCCCCCCCCCEEEHHHHHHHHHHH
FIGFYAMGQGRADFSEVMIFRSPDEKGAFLALTAATALAFFAMVGFEDSVNMAEEVTDPV
HHHHHHHCCCCCCHHHEEEEECCCCCCCEEHHHHHHHHHHHHHHCCCCCCCHHHHHCHHH
RIFPRIMLTGLGITGVIYVLVAICAVALVPVGDLSDPDKGSALTQVVRAGAPNFPFDKIF
HHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCCCCHHHHH
PFIGMFAVANSALINMLMASRLLYGLARQGVLPHGLGLVHRERRTPWVAIIFTTLLAFGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCCCHHHHHHHHHHHHHH
IYFVVTRSDLPAVSLLGGTTALLLLCVFTVVNISLLVLRKRPVERQHFKAPGWVPWVGAA
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCCCCHHHH
TCAFLAGPWARSAAQMDQYKVAGWLIGIGIVLWAATYLWNRATRHHVPGGLEHVEDLAEH
HHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
HGDSTRN
CCCCCCC
>Mature Secondary Structure 
TTATGTRTEPEQHTLKRVIGPKLLLLFIVGDILGTGVYALTGTVAGEVGGAAWAPFLVA
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHH
FLVATITALSYLELVTRYPQAAGAALYAHRAFGIHFLTFLVAFTVMCSGITSASTASNAF
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
AGFMNDGFGLGFRKDGSGILIIALGFMALVAAINFRGVGESVKANVVLTCVELSGLLMII
HHHHCCCCCCCEEECCCCEEHHHHHHHHHHHHHHCCCCCCCCCCCCEEEHHHHHHHHHHH
FIGFYAMGQGRADFSEVMIFRSPDEKGAFLALTAATALAFFAMVGFEDSVNMAEEVTDPV
HHHHHHHCCCCCCHHHEEEEECCCCCCCEEHHHHHHHHHHHHHHCCCCCCCHHHHHCHHH
RIFPRIMLTGLGITGVIYVLVAICAVALVPVGDLSDPDKGSALTQVVRAGAPNFPFDKIF
HHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCCCCHHHHH
PFIGMFAVANSALINMLMASRLLYGLARQGVLPHGLGLVHRERRTPWVAIIFTTLLAFGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCCCHHHHHHHHHHHHHH
IYFVVTRSDLPAVSLLGGTTALLLLCVFTVVNISLLVLRKRPVERQHFKAPGWVPWVGAA
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCCCCHHHH
TCAFLAGPWARSAAQMDQYKVAGWLIGIGIVLWAATYLWNRATRHHVPGGLEHVEDLAEH
HHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
HGDSTRN
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9141694; 9384377 [H]