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The map label for this gene is hesB [H]

Identifier: 119387009

GI number: 119387009

Start: 1484284

End: 1484655

Strand: Direct

Name: hesB [H]

Synonym: Pden_4304

Alternate gene names: 119387009

Gene position: 1484284-1484655 (Clockwise)

Preceding gene: 119387006

Following gene: 119387010

Centisome position: 85.79

GC content: 65.05

Gene sequence:

>372_bases
ATGTTTTCGATCCCCGGCAAATCCCCCGTGACCATCACCCAGGCGGCCGAGCGGCAGATCGCCAGGCTCATGGCCCAGAA
ATCCGCCAGCGGGCTGCGCATCGGCCTGAAGAAGGGCGGCTGCGCCGGCATGGAATACACCATGGAACTAGCCGAAACCC
CCGCCCCGGGCGACGAGGTGGTCGAACAGGGCGAGGCGCGGGTGCTGATCGCCCCTACCGCGCAGATGTTCCTGTTCGGG
ACCGAGATCGACTATGAATCCGGCCTCTTGGAATCCGGCTTCAAGTTCCGCAACCCGAATGTCACCGACAGCTGCGGCTG
CGGCGAATCGGTCAACTTCGCCCCGCTGGAAGGCTCGCGCGCGAAAGCCTGA

Upstream 100 bases:

>100_bases
CGCTTATAGCCGCATCGGCACCCGAGTCAAGCGCCCCTGGCCCTTGAGCGGCAGCTTCGATGCCCCTAAATGAGAGACAG
CGAACATAAAAAGGCCCGAG

Downstream 100 bases:

>100_bases
GCCTTTTTGCCGCAAGTTAGCGCCCACATCGCGCCAGCCGTCTTGATCGCGGGGACCCCCCGGCCTAATCCCTGTCAGAC
CAAGACAGAGGGAGAGGCAG

Product: iron-sulfur cluster assembly accessory protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 123; Mature: 123

Protein sequence:

>123_residues
MFSIPGKSPVTITQAAERQIARLMAQKSASGLRIGLKKGGCAGMEYTMELAETPAPGDEVVEQGEARVLIAPTAQMFLFG
TEIDYESGLLESGFKFRNPNVTDSCGCGESVNFAPLEGSRAKA

Sequences:

>Translated_123_residues
MFSIPGKSPVTITQAAERQIARLMAQKSASGLRIGLKKGGCAGMEYTMELAETPAPGDEVVEQGEARVLIAPTAQMFLFG
TEIDYESGLLESGFKFRNPNVTDSCGCGESVNFAPLEGSRAKA
>Mature_123_residues
MFSIPGKSPVTITQAAERQIARLMAQKSASGLRIGLKKGGCAGMEYTMELAETPAPGDEVVEQGEARVLIAPTAQMFLFG
TEIDYESGLLESGFKFRNPNVTDSCGCGESVNFAPLEGSRAKA

Specific function: Unknown

COG id: COG0316

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hesB/iscA family [H]

Homologues:

Organism=Homo sapiens, GI52426768, Length=110, Percent_Identity=40.9090909090909, Blast_Score=93, Evalue=4e-20,
Organism=Homo sapiens, GI160420328, Length=83, Percent_Identity=34.9397590361446, Blast_Score=63, Evalue=4e-11,
Organism=Escherichia coli, GI1788877, Length=104, Percent_Identity=38.4615384615385, Blast_Score=89, Evalue=1e-19,
Organism=Escherichia coli, GI1787974, Length=102, Percent_Identity=38.2352941176471, Blast_Score=75, Evalue=2e-15,
Organism=Escherichia coli, GI1786351, Length=104, Percent_Identity=31.7307692307692, Blast_Score=66, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI193209025, Length=105, Percent_Identity=44.7619047619048, Blast_Score=97, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI25146411, Length=105, Percent_Identity=44.7619047619048, Blast_Score=97, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6323001, Length=101, Percent_Identity=34.6534653465347, Blast_Score=78, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24642263, Length=108, Percent_Identity=40.7407407407407, Blast_Score=88, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000361
- InterPro:   IPR016092
- InterPro:   IPR017870 [H]

Pfam domain/function: PF01521 Fe-S_biosyn [H]

EC number: NA

Molecular weight: Translated: 13034; Mature: 13034

Theoretical pI: Translated: 4.68; Mature: 4.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFSIPGKSPVTITQAAERQIARLMAQKSASGLRIGLKKGGCAGMEYTMELAETPAPGDEV
CCCCCCCCCEEEHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHCCCCCCHHH
VEQGEARVLIAPTAQMFLFGTEIDYESGLLESGFKFRNPNVTDSCGCGESVNFAPLEGSR
HHCCCCEEEEECCCEEEEECCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCCCC
AKA
CCC
>Mature Secondary Structure
MFSIPGKSPVTITQAAERQIARLMAQKSASGLRIGLKKGGCAGMEYTMELAETPAPGDEV
CCCCCCCCCEEEHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHCCCCCCHHH
VEQGEARVLIAPTAQMFLFGTEIDYESGLLESGFKFRNPNVTDSCGCGESVNFAPLEGSR
HHCCCCEEEEECCCEEEEECCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCCCC
AKA
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8106314 [H]