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The map label for this gene is xanB [H]

Identifier: 119386745

GI number: 119386745

Start: 1188106

End: 1189533

Strand: Direct

Name: xanB [H]

Synonym: Pden_4038

Alternate gene names: 119386745

Gene position: 1188106-1189533 (Clockwise)

Preceding gene: 119386744

Following gene: 119386746

Centisome position: 68.67

GC content: 68.21

Gene sequence:

>1428_bases
ATGACGATCACCCCTGTTCTTCTGGCCGGAGGCTCGGGCACCCGGCTTTGGCCCGTCTCGCGCAAGAGTTTTCCCAAGCA
GTTCGCCCCGCTGGTGGGCGATGACAGCCTGTTCCAGGCCTCCGCCCGCCGCCTGTCAGGTCCGCGCTACGGCGCGCCGC
TGGTGATGACCAATGCCGATTTCCGCTTCATCGTCGCCGAACAGCTGGACCAGATCGGCATCGCGCCGGCGGCGATCCTG
ATCGAGCCCTCGGGCCGCAACACCGCCCCCGCGATCCTTGCCGCGGCGCTTCGCGCGGCCGAGACGGACCCCGATGCCGT
GCTGCTGGTCGCGCCGTCGGATCATGTCGTGCCCGATACCGAGGCATTCGGCCGCGCCGTCGATCTGGGCCTGCCCGCGG
CACGGGCCGGCCGCATCGTCACCTTCGGCATCACCCCCACCCGCCCCGAGACCGGCTATGGCTATATGGAGGCCGAGGGC
GGCAACGGCGGCGAAGGCCCGCTGGTGCTGAAACGCTTCGTCGAAAAGCCGGATGCCGAGAATGCGGCACGGATGATCGC
TCAGGGCGATTTCCTGTGGAACGCAGGCATCTTCCTGTTCGCCGCCCGCACCATGGTCGAGGCATTCGAAACCCATGCGC
CGGAATATCTGGGCCCCGTGCAGGCGGCGCTGACCGAGGCGCGCATGGACCTGGGTTTCCTGAGGCTTGCGCCCGAGCCC
TGGGACGGGCTGCCGGACCGCTCGGTCGACTACGCCGTGCTGGAAAAGGCCGGCAACCTGTCGGTGGTGCGCTATTCGGG
CCATTGGTCGGATCTGGGCGGCTGGGATGCGGTCTGGCACGAGATCCAGCGGGACGAACCGGCCGAGCGCGGCGCCGTGG
TGGATGGGCGCTCGACCGCGATCGACTGCGACAACGTGCTGTTGCGGGCGCAGGACGAGGGGATCGAGGTCGTCGGCATC
GGCCTTAGGGACGTGATGGTCGTGGCCACCGACGACGCCGTGCTGGTGGCCGGCATGGACCGCGCGCAGGAGGTGCGCAA
GGCGGTCAGCGCGCTCAAGGCCAAGGGCGCCCGCCAGGCCGAGCATTTCCTGCGCGATCATCGCCCCTGGGGCTGGTTCG
AGACGCTGGCGCTGGCCGACCGCTTCCAGGTCAAGCGCATCGTCGTCAATCCCGGCGCGGCGCTGTCGCTGCAATCGCAT
TTCCATCGGTCCGAGCATTGGATCGTGGTGTCCGGCACTGCGCGGGTGACGGTTGACGAGACGGTGACGCTGCTGACCGA
GAACCAGTCGATCTATGTGCCGCTGGGCGCGGTCCACCGGCTGGAAAACCCCGGCAAGGTGCCGATGGTGCTGATCGAGG
TGCAGACCGGCGTCTATCTGGGCGAAGACGATATCGTGCGCTACGAGGATGTCTATTCGCGCGGCTGA

Upstream 100 bases:

>100_bases
ATCCCGGGCATCCTGACGTTTTGCGCAACTTGCGCGCGCAGGGAAGCCGCCGGATAACGAAAGCGTATGGTAACGGCCCC
GTGCCGATGGAGCGATTTTC

Downstream 100 bases:

>100_bases
CCGCCGCTCGCGGCATCGTGCAGGGTGCGACGGCTTGCGGTGCCGACACCGGCCGTCTAACCATGGCCGGCGATGAAATG
GATGACCAAATCGCTGATCC

Product: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase

Products: NA

Alternate protein names: Mannose-6-phosphate isomerase; Phosphohexomutase; Phosphomannose isomerase; PMI; Mannose-1-phosphate guanylyl transferase; GDP-mannose pyrophosphorylase; GMP; GMPP [H]

Number of amino acids: Translated: 475; Mature: 474

Protein sequence:

>475_residues
MTITPVLLAGGSGTRLWPVSRKSFPKQFAPLVGDDSLFQASARRLSGPRYGAPLVMTNADFRFIVAEQLDQIGIAPAAIL
IEPSGRNTAPAILAAALRAAETDPDAVLLVAPSDHVVPDTEAFGRAVDLGLPAARAGRIVTFGITPTRPETGYGYMEAEG
GNGGEGPLVLKRFVEKPDAENAARMIAQGDFLWNAGIFLFAARTMVEAFETHAPEYLGPVQAALTEARMDLGFLRLAPEP
WDGLPDRSVDYAVLEKAGNLSVVRYSGHWSDLGGWDAVWHEIQRDEPAERGAVVDGRSTAIDCDNVLLRAQDEGIEVVGI
GLRDVMVVATDDAVLVAGMDRAQEVRKAVSALKAKGARQAEHFLRDHRPWGWFETLALADRFQVKRIVVNPGAALSLQSH
FHRSEHWIVVSGTARVTVDETVTLLTENQSIYVPLGAVHRLENPGKVPMVLIEVQTGVYLGEDDIVRYEDVYSRG

Sequences:

>Translated_475_residues
MTITPVLLAGGSGTRLWPVSRKSFPKQFAPLVGDDSLFQASARRLSGPRYGAPLVMTNADFRFIVAEQLDQIGIAPAAIL
IEPSGRNTAPAILAAALRAAETDPDAVLLVAPSDHVVPDTEAFGRAVDLGLPAARAGRIVTFGITPTRPETGYGYMEAEG
GNGGEGPLVLKRFVEKPDAENAARMIAQGDFLWNAGIFLFAARTMVEAFETHAPEYLGPVQAALTEARMDLGFLRLAPEP
WDGLPDRSVDYAVLEKAGNLSVVRYSGHWSDLGGWDAVWHEIQRDEPAERGAVVDGRSTAIDCDNVLLRAQDEGIEVVGI
GLRDVMVVATDDAVLVAGMDRAQEVRKAVSALKAKGARQAEHFLRDHRPWGWFETLALADRFQVKRIVVNPGAALSLQSH
FHRSEHWIVVSGTARVTVDETVTLLTENQSIYVPLGAVHRLENPGKVPMVLIEVQTGVYLGEDDIVRYEDVYSRG
>Mature_474_residues
TITPVLLAGGSGTRLWPVSRKSFPKQFAPLVGDDSLFQASARRLSGPRYGAPLVMTNADFRFIVAEQLDQIGIAPAAILI
EPSGRNTAPAILAAALRAAETDPDAVLLVAPSDHVVPDTEAFGRAVDLGLPAARAGRIVTFGITPTRPETGYGYMEAEGG
NGGEGPLVLKRFVEKPDAENAARMIAQGDFLWNAGIFLFAARTMVEAFETHAPEYLGPVQAALTEARMDLGFLRLAPEPW
DGLPDRSVDYAVLEKAGNLSVVRYSGHWSDLGGWDAVWHEIQRDEPAERGAVVDGRSTAIDCDNVLLRAQDEGIEVVGIG
LRDVMVVATDDAVLVAGMDRAQEVRKAVSALKAKGARQAEHFLRDHRPWGWFETLALADRFQVKRIVVNPGAALSLQSHF
HRSEHWIVVSGTARVTVDETVTLLTENQSIYVPLGAVHRLENPGKVPMVLIEVQTGVYLGEDDIVRYEDVYSRG

Specific function: Involved in xanthan production [H]

COG id: COG0836

COG function: function code M; Mannose-1-phosphate guanylyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mannose-6-phosphate isomerase type 2 family [H]

Homologues:

Organism=Escherichia coli, GI1788362, Length=477, Percent_Identity=45.0733752620545, Blast_Score=399, Evalue=1e-112,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011051
- InterPro:   IPR006375
- InterPro:   IPR001538
- InterPro:   IPR005835
- InterPro:   IPR014710 [H]

Pfam domain/function: PF01050 MannoseP_isomer; PF00483 NTP_transferase [H]

EC number: =5.3.1.8; =2.7.7.13 [H]

Molecular weight: Translated: 51513; Mature: 51382

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTITPVLLAGGSGTRLWPVSRKSFPKQFAPLVGDDSLFQASARRLSGPRYGAPLVMTNAD
CCCCEEEEECCCCCEEEECCHHCCCHHHCCCCCCCHHHHHHHHHCCCCCCCCCEEEECCC
FRFIVAEQLDQIGIAPAAILIEPSGRNTAPAILAAALRAAETDPDAVLLVAPSDHVVPDT
EEEEEHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCH
EAFGRAVDLGLPAARAGRIVTFGITPTRPETGYGYMEAEGGNGGEGPLVLKRFVEKPDAE
HHHCCEEECCCCCHHCCCEEEECCCCCCCCCCCCEEEECCCCCCCCHHHHHHHHCCCCHH
NAARMIAQGDFLWNAGIFLFAARTMVEAFETHAPEYLGPVQAALTEARMDLGFLRLAPEP
HHHHHHHCCCEEECCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCEEEECCCC
WDGLPDRSVDYAVLEKAGNLSVVRYSGHWSDLGGWDAVWHEIQRDEPAERGAVVDGRSTA
CCCCCCCCCCHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHHCCCCHHCCCEECCCCCE
IDCDNVLLRAQDEGIEVVGIGLRDVMVVATDDAVLVAGMDRAQEVRKAVSALKAKGARQA
EECCCEEEEECCCCEEEEEECCEEEEEEEECCEEEEECCHHHHHHHHHHHHHHHCCHHHH
EHFLRDHRPWGWFETLALADRFQVKRIVVNPGAALSLQSHFHRSEHWIVVSGTARVTVDE
HHHHHHCCCCCHHHHHHHHHHHEEEEEEECCCCEEEEHHHCCCCCCEEEEECCEEEEECC
TVTLLTENQSIYVPLGAVHRLENPGKVPMVLIEVQTGVYLGEDDIVRYEDVYSRG
EEEEEECCCEEEEECHHHHHCCCCCCCCEEEEEEECCEEECCCCCEEHHHHHCCC
>Mature Secondary Structure 
TITPVLLAGGSGTRLWPVSRKSFPKQFAPLVGDDSLFQASARRLSGPRYGAPLVMTNAD
CCCEEEEECCCCCEEEECCHHCCCHHHCCCCCCCHHHHHHHHHCCCCCCCCCEEEECCC
FRFIVAEQLDQIGIAPAAILIEPSGRNTAPAILAAALRAAETDPDAVLLVAPSDHVVPDT
EEEEEHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCH
EAFGRAVDLGLPAARAGRIVTFGITPTRPETGYGYMEAEGGNGGEGPLVLKRFVEKPDAE
HHHCCEEECCCCCHHCCCEEEECCCCCCCCCCCCEEEECCCCCCCCHHHHHHHHCCCCHH
NAARMIAQGDFLWNAGIFLFAARTMVEAFETHAPEYLGPVQAALTEARMDLGFLRLAPEP
HHHHHHHCCCEEECCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCEEEECCCC
WDGLPDRSVDYAVLEKAGNLSVVRYSGHWSDLGGWDAVWHEIQRDEPAERGAVVDGRSTA
CCCCCCCCCCHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHHCCCCHHCCCEECCCCCE
IDCDNVLLRAQDEGIEVVGIGLRDVMVVATDDAVLVAGMDRAQEVRKAVSALKAKGARQA
EECCCEEEEECCCCEEEEEECCEEEEEEEECCEEEEECCHHHHHHHHHHHHHHHCCHHHH
EHFLRDHRPWGWFETLALADRFQVKRIVVNPGAALSLQSHFHRSEHWIVVSGTARVTVDE
HHHHHHCCCCCHHHHHHHHHHHEEEEEEECCCCEEEEHHHCCCCCCEEEEECCEEEEECC
TVTLLTENQSIYVPLGAVHRLENPGKVPMVLIEVQTGVYLGEDDIVRYEDVYSRG
EEEEEECCCEEEEECHHHHHCCCCCCCCEEEEEEECCEEECCCCCEEHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1370280; 11589581 [H]