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The map label for this gene is mreB [H]

Identifier: 119386739

GI number: 119386739

Start: 1181383

End: 1182483

Strand: Direct

Name: mreB [H]

Synonym: Pden_4032

Alternate gene names: 119386739

Gene position: 1181383-1182483 (Clockwise)

Preceding gene: 119386737

Following gene: 119386740

Centisome position: 68.28

GC content: 67.3

Gene sequence:

>1101_bases
ATGGCCGTTCGCAAAAGGACGGCAGAAACGGCCGTCATGGCAGGGACGGCGGAAGGGGTAGTTCACATGGCCTTTGGCGG
GTTGTTTTCCACCGATATCGCGATCGACCTCGGGACCGCGAACACGCTGATCTATGTCAAGGGCAAGGGCGTCATCCTGA
ACGAGCCTTCGGTCGTCGCCTATCACGTCAAGGACGGCAAGAAGCAGGTGCTGGCCGTGGGCGAGGACGCCAAGCTGATG
CTGGGCCGCACGCCCGGCAGCATCGAGGCGATCCGGCCGATGCGCGAGGGCGTCATCGCCGATTTCGACAGCGCCGAGGA
AATGATCAAGCATTTCATCAAGAAGGTGTTCAAGCGCACCAGCTTCTCGAAGCCCAAGGTCATCGTCTGCGTGCCCCATG
GCGCCACGCCGGTCGAAAAGCGCGCCATCCGCCAGTCGGTGCTGTCGGCCGGGGCGCGCCGCGCCGGGCTGATCGCCGAG
CCGATCGCGGCCGCCATCGGCGCCGGCATGCCGATCACCGAGCCGACCGGCAGCATGGTCGTCGATATCGGCGGCGGCAC
CACCGAGGTCGCGGTGCTGTCCTTGGGCGACGTGGTCTATGCGCGTTCGGTCCGCATCGGCGGCGACCGCATGGACGATG
CGCTGATCAACTACCTGCGCCGCAACCACAACCTGCTGATCGGCGAATCCACCGCCGAGCGGGTCAAGACCAGCATCGGC
ACCGCCCGCATGCCCGACGACGGGCGCGGCGCCACGATCATGGTGCGCGGCCGCGACCTCCTGAACGGCATTCCCAAGGA
GATGGAGATCACCCAGGCCATGGTCGCCGAGGCGCTGGCCGAGCCGGTGCAGCAGATCTGCGAGGCGGTGATGGTGGCGC
TGGAGGCGACGCCGCCCGACCTGGCCGCCGATATCGTGGACCGGGGCGTGATGCTGACCGGCGGCGGCGCCATGCTGGGC
GAGCTGGACCTGGCGCTGCGCGAGCAGACCGGGCTGATGATCAGCCTGGCCGACCAGCCGATGAGCTGCGTGGCGCTTGG
CACCGGCAAGGCGCTGGAGTTCGAAAAGCAGCTGCGCCACGTGATCGACTACGACAGCTGA

Upstream 100 bases:

>100_bases
CCGCAGGACGGGACGCATCATTTTTCCGGTTTCCCCGCGCCCGGGCTCGGCCTATATGTCCAGCACCTTCGACGGGGCGA
CTCGCCGGGGCAATCGGGCA

Downstream 100 bases:

>100_bases
GCGGGTTCGGCCCATGGCGCGCAAGGGCCCAGATTACGCGGCTCCGGTCCGCCGCATCCTGGTTTCGCTGCTGGTGCTGG
TGCTGCTGGCGGTGTTCCTG

Product: rod shape-determining protein MreB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 366; Mature: 365

Protein sequence:

>366_residues
MAVRKRTAETAVMAGTAEGVVHMAFGGLFSTDIAIDLGTANTLIYVKGKGVILNEPSVVAYHVKDGKKQVLAVGEDAKLM
LGRTPGSIEAIRPMREGVIADFDSAEEMIKHFIKKVFKRTSFSKPKVIVCVPHGATPVEKRAIRQSVLSAGARRAGLIAE
PIAAAIGAGMPITEPTGSMVVDIGGGTTEVAVLSLGDVVYARSVRIGGDRMDDALINYLRRNHNLLIGESTAERVKTSIG
TARMPDDGRGATIMVRGRDLLNGIPKEMEITQAMVAEALAEPVQQICEAVMVALEATPPDLAADIVDRGVMLTGGGAMLG
ELDLALREQTGLMISLADQPMSCVALGTGKALEFEKQLRHVIDYDS

Sequences:

>Translated_366_residues
MAVRKRTAETAVMAGTAEGVVHMAFGGLFSTDIAIDLGTANTLIYVKGKGVILNEPSVVAYHVKDGKKQVLAVGEDAKLM
LGRTPGSIEAIRPMREGVIADFDSAEEMIKHFIKKVFKRTSFSKPKVIVCVPHGATPVEKRAIRQSVLSAGARRAGLIAE
PIAAAIGAGMPITEPTGSMVVDIGGGTTEVAVLSLGDVVYARSVRIGGDRMDDALINYLRRNHNLLIGESTAERVKTSIG
TARMPDDGRGATIMVRGRDLLNGIPKEMEITQAMVAEALAEPVQQICEAVMVALEATPPDLAADIVDRGVMLTGGGAMLG
ELDLALREQTGLMISLADQPMSCVALGTGKALEFEKQLRHVIDYDS
>Mature_365_residues
AVRKRTAETAVMAGTAEGVVHMAFGGLFSTDIAIDLGTANTLIYVKGKGVILNEPSVVAYHVKDGKKQVLAVGEDAKLML
GRTPGSIEAIRPMREGVIADFDSAEEMIKHFIKKVFKRTSFSKPKVIVCVPHGATPVEKRAIRQSVLSAGARRAGLIAEP
IAAAIGAGMPITEPTGSMVVDIGGGTTEVAVLSLGDVVYARSVRIGGDRMDDALINYLRRNHNLLIGESTAERVKTSIGT
ARMPDDGRGATIMVRGRDLLNGIPKEMEITQAMVAEALAEPVQQICEAVMVALEATPPDLAADIVDRGVMLTGGGAMLGE
LDLALREQTGLMISLADQPMSCVALGTGKALEFEKQLRHVIDYDS

Specific function: Involved in formation of the rod shape of the cell. May act as a negative regulator of ftsI [H]

COG id: COG1077

COG function: function code D; Actin-like ATPase involved in cell morphogenesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsA/mreB family [H]

Homologues:

Organism=Escherichia coli, GI87082236, Length=334, Percent_Identity=60.4790419161677, Blast_Score=383, Evalue=1e-107,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001023
- InterPro:   IPR004753 [H]

Pfam domain/function: PF06723 MreB_Mbl [H]

EC number: NA

Molecular weight: Translated: 38773; Mature: 38642

Theoretical pI: Translated: 6.27; Mature: 6.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVRKRTAETAVMAGTAEGVVHMAFGGLFSTDIAIDLGTANTLIYVKGKGVILNEPSVVA
CCCCHHCHHHHEEECCCCCEEEEHHCCCEECCEEEEECCCCEEEEEECCEEEECCCCEEE
YHVKDGKKQVLAVGEDAKLMLGRTPGSIEAIRPMREGVIADFDSAEEMIKHFIKKVFKRT
EEECCCCEEEEEECCCCEEEEECCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHC
SFSKPKVIVCVPHGATPVEKRAIRQSVLSAGARRAGLIAEPIAAAIGAGMPITEPTGSMV
CCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCHHCCCHHHHHHHHHCCCCCCCCCCCCEE
VDIGGGTTEVAVLSLGDVVYARSVRIGGDRMDDALINYLRRNHNLLIGESTAERVKTSIG
EEECCCCEEEEEEECCCEEEEEEEEECCCHHHHHHHHHHHCCCCEEEECCHHHHHHHHCC
TARMPDDGRGATIMVRGRDLLNGIPKEMEITQAMVAEALAEPVQQICEAVMVALEATPPD
CCCCCCCCCCCEEEEECCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
LAADIVDRGVMLTGGGAMLGELDLALREQTGLMISLADQPMSCVALGTGKALEFEKQLRH
HHHHHHHCCEEEECCCCEEHHHHHHHHHCCCEEEEECCCCCEEEEECCCCCHHHHHHHHH
VIDYDS
HHCCCC
>Mature Secondary Structure 
AVRKRTAETAVMAGTAEGVVHMAFGGLFSTDIAIDLGTANTLIYVKGKGVILNEPSVVA
CCCHHCHHHHEEECCCCCEEEEHHCCCEECCEEEEECCCCEEEEEECCEEEECCCCEEE
YHVKDGKKQVLAVGEDAKLMLGRTPGSIEAIRPMREGVIADFDSAEEMIKHFIKKVFKRT
EEECCCCEEEEEECCCCEEEEECCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHC
SFSKPKVIVCVPHGATPVEKRAIRQSVLSAGARRAGLIAEPIAAAIGAGMPITEPTGSMV
CCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCHHCCCHHHHHHHHHCCCCCCCCCCCCEE
VDIGGGTTEVAVLSLGDVVYARSVRIGGDRMDDALINYLRRNHNLLIGESTAERVKTSIG
EEECCCCEEEEEEECCCEEEEEEEEECCCHHHHHHHHHHHCCCCEEEECCHHHHHHHHCC
TARMPDDGRGATIMVRGRDLLNGIPKEMEITQAMVAEALAEPVQQICEAVMVALEATPPD
CCCCCCCCCCCEEEEECCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
LAADIVDRGVMLTGGGAMLGELDLALREQTGLMISLADQPMSCVALGTGKALEFEKQLRH
HHHHHHHCCEEEECCCCEEHHHHHHHHHCCCEEEEECCCCCEEEEECCCCCHHHHHHHHH
VIDYDS
HHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]