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The map label for this gene is cdsA [H]

Identifier: 119386703

GI number: 119386703

Start: 1134611

End: 1135465

Strand: Direct

Name: cdsA [H]

Synonym: Pden_3996

Alternate gene names: 119386703

Gene position: 1134611-1135465 (Clockwise)

Preceding gene: 119386702

Following gene: 119386704

Centisome position: 65.58

GC content: 69.59

Gene sequence:

>855_bases
ATGAGCGGGGACGGACCACAGCCGGGCCGGTTGCGCGGCGCCTTGCAGCGCGGACGCGACAAATGGGCCGATCTCTGGCC
GCGCCTTCTGTCGGGCGCGGTGCTGGCGGTGCTGGGGCTGTTGCTGCTGCTGTCCTCGGGGCTTTGGATCCGGCTGGGCG
TCTCGGCCGTCATCGGGGTGATGATGTGGGAACTGGCGCGGCTGACCGGCTGGCGCCATCCCGAATTCCGCAGCCCGCGC
CATCCGGTGCTGATCGCCATCCTGTCGGGGCTGGTGATGCTGGCCATGCTGGTGCTGCCCGGCGACTGGCCGATGGCGCT
GGCACTGGTGCCGATGATCGCCGGCTGGCACGGCACGCATGAACACGAACGCCCGGCCTATCTGCTGTTCACCCTGGCGA
TCCTGGGTGCCGGCTATGCGCTGGTGGTGATCCGCGAGGTGATGGGCCTGCCGACGCTGGCCTGGATCGTCGGCACCGTG
GTGCTGTCCGACGTGCTGGGCTATTTCATCGGCCGCAAGCTGGGCGGGCCGCGCTTCTGGCCGGCGATCAGCCCCAAGAA
GACCTGGAGCGGCACCATCGCCGGCTGGGCGGGCGCGCTGGTGCTGGCGCTGGTCCTGATGCTGGCCGGGCAGGCGCCCT
GGCCGGTCCTGGTGCTCGGCCCGCTGATCGCGCTGGCCGGGCAGTTCGGCGACATCGCGGAAAGCTGGCTCAAGCGCCGG
GTCGGGGTCAAGGACAGTTCCGATCTGATCCCCGGCCATGGCGGCGTCCTGGACCGTTTCGACGCCATGTCCGGGGCGTT
GCTCATGGCGCTGCTGCTTTTGATCGGCGATCTCTTACCCGTTATCGGAGGCTGA

Upstream 100 bases:

>100_bases
AATATGAGTTCACCCAGACGCTCTGGCCGGACTTCACGCCCGAGCATCTGGCCGAGATCCTCGACCGCTACGGGCTGCGC
GACCGGCGCTTCGGCGGCGC

Downstream 100 bases:

>100_bases
GACGATGCGCAGCATATCCGTGCTGGGCGCGACCGGGTCGGTCGGCGAAAGCGCATTCGATCTGTTGATGGGGGCCGGCG
GCCCCGAGCGCTTCCGCACC

Product: phosphatidate cytidylyltransferase

Products: NA

Alternate protein names: CDP-DAG synthase; CDP-DG synthase; CDP-diacylglycerol synthase; CDS; CDP-diglyceride pyrophosphorylase; CDP-diglyceride synthase; CTP:phosphatidate cytidylyltransferase [H]

Number of amino acids: Translated: 284; Mature: 283

Protein sequence:

>284_residues
MSGDGPQPGRLRGALQRGRDKWADLWPRLLSGAVLAVLGLLLLLSSGLWIRLGVSAVIGVMMWELARLTGWRHPEFRSPR
HPVLIAILSGLVMLAMLVLPGDWPMALALVPMIAGWHGTHEHERPAYLLFTLAILGAGYALVVIREVMGLPTLAWIVGTV
VLSDVLGYFIGRKLGGPRFWPAISPKKTWSGTIAGWAGALVLALVLMLAGQAPWPVLVLGPLIALAGQFGDIAESWLKRR
VGVKDSSDLIPGHGGVLDRFDAMSGALLMALLLLIGDLLPVIGG

Sequences:

>Translated_284_residues
MSGDGPQPGRLRGALQRGRDKWADLWPRLLSGAVLAVLGLLLLLSSGLWIRLGVSAVIGVMMWELARLTGWRHPEFRSPR
HPVLIAILSGLVMLAMLVLPGDWPMALALVPMIAGWHGTHEHERPAYLLFTLAILGAGYALVVIREVMGLPTLAWIVGTV
VLSDVLGYFIGRKLGGPRFWPAISPKKTWSGTIAGWAGALVLALVLMLAGQAPWPVLVLGPLIALAGQFGDIAESWLKRR
VGVKDSSDLIPGHGGVLDRFDAMSGALLMALLLLIGDLLPVIGG
>Mature_283_residues
SGDGPQPGRLRGALQRGRDKWADLWPRLLSGAVLAVLGLLLLLSSGLWIRLGVSAVIGVMMWELARLTGWRHPEFRSPRH
PVLIAILSGLVMLAMLVLPGDWPMALALVPMIAGWHGTHEHERPAYLLFTLAILGAGYALVVIREVMGLPTLAWIVGTVV
LSDVLGYFIGRKLGGPRFWPAISPKKTWSGTIAGWAGALVLALVLMLAGQAPWPVLVLGPLIALAGQFGDIAESWLKRRV
GVKDSSDLIPGHGGVLDRFDAMSGALLMALLLLIGDLLPVIGG

Specific function: Phospholipid biosynthesis. [C]

COG id: COG0575

COG function: function code I; CDP-diglyceride synthetase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDS family [H]

Homologues:

Organism=Escherichia coli, GI87081696, Length=117, Percent_Identity=41.025641025641, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1787677, Length=103, Percent_Identity=36.8932038834951, Blast_Score=69, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000374 [H]

Pfam domain/function: PF01148 CTP_transf_1 [H]

EC number: =2.7.7.41 [H]

Molecular weight: Translated: 30357; Mature: 30226

Theoretical pI: Translated: 10.64; Mature: 10.64

Prosite motif: PS01315 CDS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGDGPQPGRLRGALQRGRDKWADLWPRLLSGAVLAVLGLLLLLSSGLWIRLGVSAVIGV
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHH
MMWELARLTGWRHPEFRSPRHPVLIAILSGLVMLAMLVLPGDWPMALALVPMIAGWHGTH
HHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCC
EHERPAYLLFTLAILGAGYALVVIREVMGLPTLAWIVGTVVLSDVLGYFIGRKLGGPRFW
CCCCHHHHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
PAISPKKTWSGTIAGWAGALVLALVLMLAGQAPWPVLVLGPLIALAGQFGDIAESWLKRR
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHH
VGVKDSSDLIPGHGGVLDRFDAMSGALLMALLLLIGDLLPVIGG
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SGDGPQPGRLRGALQRGRDKWADLWPRLLSGAVLAVLGLLLLLSSGLWIRLGVSAVIGV
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHH
MMWELARLTGWRHPEFRSPRHPVLIAILSGLVMLAMLVLPGDWPMALALVPMIAGWHGTH
HHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCC
EHERPAYLLFTLAILGAGYALVVIREVMGLPTLAWIVGTVVLSDVLGYFIGRKLGGPRFW
CCCCHHHHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
PAISPKKTWSGTIAGWAGALVLALVLMLAGQAPWPVLVLGPLIALAGQFGDIAESWLKRR
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHH
VGVKDSSDLIPGHGGVLDRFDAMSGALLMALLLLIGDLLPVIGG
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]