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The map label for this gene is frr

Identifier: 119386701

GI number: 119386701

Start: 1133313

End: 1133876

Strand: Direct

Name: frr

Synonym: Pden_3994

Alternate gene names: 119386701

Gene position: 1133313-1133876 (Clockwise)

Preceding gene: 119386700

Following gene: 119386702

Centisome position: 65.51

GC content: 64.54

Gene sequence:

>564_bases
ATGTCCGACGAGATCGAGATCGACACCGACGACCTGGAGCGCCGCATGAAGGGCGCGATGGAATCCCTGCGCCATGAATT
CGCCTCGCTGCGCACCGGCCGCGCCTCGGCCAGCATGGTCGAGCCGATCATGGTCGATGCCTACGGCTCGCCCACGCCGA
TCAACCAGATCGGCACGGTGAACGTGCCCGAACCGCGCATGGTCACGATCAACATCTGGGACAAGGGCCTGGTCGGCAAG
GCCGAGAAGGCGATCCGCGAATCGGGCCTGGGCATCAACCCGCAGCTCAACGGCACCATCATCATGCTGCCGATCCCCGA
GCTGAACGAAGAGCGCCGGCGCGAACTGACCCGCGTCGCCGCGCAATATGCCGAACATGCCCGCGTCGCCATCCGCAACG
TGCGGCGCGACGGCATGGACCAGATCAAGAAGGCCAAGTCCTCGGGCATGTCCGAGGACGACCAGAAGTTCTGGGAGGGC
GCCGTGCAGGAACTGACCGACAAGATGATCGCCTCGGTGGATCAGGCGCTCGAGGCCAAGCAAGCCGAAATCATGCAGGT
CTGA

Upstream 100 bases:

>100_bases
ATACGCGCGTCCATGGGTAAAATCCCCGTATAGGCTTTGCCATGCGGGCGTGGCTCGGCTAAAAGCGGCGAAAATCACAG
CACAGAGGCCATGACCGAGC

Downstream 100 bases:

>100_bases
CGCATGGCCGAGATCGCAGCCAGCCTGTCGAAGCCCGGCGGAGGGGACCAGCGGCCCCGTCATGTCGCCATCATCATGGA
TGGCAACGGCCGCTGGGCCA

Product: ribosome recycling factor

Products: NA

Alternate protein names: RRF; Ribosome-releasing factor

Number of amino acids: Translated: 187; Mature: 186

Protein sequence:

>187_residues
MSDEIEIDTDDLERRMKGAMESLRHEFASLRTGRASASMVEPIMVDAYGSPTPINQIGTVNVPEPRMVTINIWDKGLVGK
AEKAIRESGLGINPQLNGTIIMLPIPELNEERRRELTRVAAQYAEHARVAIRNVRRDGMDQIKKAKSSGMSEDDQKFWEG
AVQELTDKMIASVDQALEAKQAEIMQV

Sequences:

>Translated_187_residues
MSDEIEIDTDDLERRMKGAMESLRHEFASLRTGRASASMVEPIMVDAYGSPTPINQIGTVNVPEPRMVTINIWDKGLVGK
AEKAIRESGLGINPQLNGTIIMLPIPELNEERRRELTRVAAQYAEHARVAIRNVRRDGMDQIKKAKSSGMSEDDQKFWEG
AVQELTDKMIASVDQALEAKQAEIMQV
>Mature_186_residues
SDEIEIDTDDLERRMKGAMESLRHEFASLRTGRASASMVEPIMVDAYGSPTPINQIGTVNVPEPRMVTINIWDKGLVGKA
EKAIRESGLGINPQLNGTIIMLPIPELNEERRRELTRVAAQYAEHARVAIRNVRRDGMDQIKKAKSSGMSEDDQKFWEGA
VQELTDKMIASVDQALEAKQAEIMQV

Specific function: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another

COG id: COG0233

COG function: function code J; Ribosome recycling factor

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RRF family

Homologues:

Organism=Homo sapiens, GI20270317, Length=180, Percent_Identity=30, Blast_Score=100, Evalue=6e-22,
Organism=Homo sapiens, GI291042689, Length=184, Percent_Identity=29.3478260869565, Blast_Score=92, Evalue=3e-19,
Organism=Escherichia coli, GI1786368, Length=177, Percent_Identity=44.0677966101695, Blast_Score=156, Evalue=7e-40,
Organism=Drosophila melanogaster, GI24661488, Length=180, Percent_Identity=24.4444444444444, Blast_Score=77, Evalue=8e-15,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): RRF_PARDP (A1B966)

Other databases:

- EMBL:   CP000490
- RefSeq:   YP_917756.1
- ProteinModelPortal:   A1B966
- SMR:   A1B966
- STRING:   A1B966
- GeneID:   4582545
- GenomeReviews:   CP000490_GR
- KEGG:   pde:Pden_3994
- eggNOG:   COG0233
- HOGENOM:   HBG533975
- OMA:   YYGAETP
- ProtClustDB:   PRK00083
- GO:   GO:0005737
- HAMAP:   MF_00040
- InterPro:   IPR002661
- InterPro:   IPR015998
- PANTHER:   PTHR20982
- PANTHER:   PTHR20982:SF3
- TIGRFAMs:   TIGR00496

Pfam domain/function: PF01765 RRF; SSF55194 Ribosome_recyc_fac

EC number: NA

Molecular weight: Translated: 20892; Mature: 20761

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.9 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
5.4 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDEIEIDTDDLERRMKGAMESLRHEFASLRTGRASASMVEPIMVDAYGSPTPINQIGTV
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHEECCCCCCCCCCCCCC
NVPEPRMVTINIWDKGLVGKAEKAIRESGLGINPQLNGTIIMLPIPELNEERRRELTRVA
CCCCCCEEEEEECCCCCCHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHH
AQYAEHARVAIRNVRRDGMDQIKKAKSSGMSEDDQKFWEGAVQELTDKMIASVDQALEAK
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QAEIMQV
HHHHHCC
>Mature Secondary Structure 
SDEIEIDTDDLERRMKGAMESLRHEFASLRTGRASASMVEPIMVDAYGSPTPINQIGTV
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHEECCCCCCCCCCCCCC
NVPEPRMVTINIWDKGLVGKAEKAIRESGLGINPQLNGTIIMLPIPELNEERRRELTRVA
CCCCCCEEEEEECCCCCCHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHH
AQYAEHARVAIRNVRRDGMDQIKKAKSSGMSEDDQKFWEGAVQELTDKMIASVDQALEAK
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QAEIMQV
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA