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The map label for this gene is ffh [H]

Identifier: 119386585

GI number: 119386585

Start: 1013103

End: 1014599

Strand: Direct

Name: ffh [H]

Synonym: Pden_3878

Alternate gene names: 119386585

Gene position: 1013103-1014599 (Clockwise)

Preceding gene: 119386582

Following gene: 119386586

Centisome position: 58.56

GC content: 66.47

Gene sequence:

>1497_bases
ATGTTTGAAAACCTGTCCGACCGCCTTGGCGGCGTCTTCGACCGGCTGACCAAGCAGGGCGCGCTGTCCGAGGACGACGT
CGCCGCCGCCATGCGCGAGGTGCGCGTCGCGCTGCTCGAGGCCGATGTCTCGCTGCCCGTCGCGCGCAATTTCGTCAAGG
CGGTGACGCAGAAGGCCACGGGAGCCGCCGTCACCAAGTCGATCACGCCCGGCCAGCAGGTCGTGAAGATCGTCCATGAC
GAGCTGATCAAGGTTCTGCAGGGCGAGGGTGCGCCCGATGCGCTGCGCATCGACAACCCGCCCGCGCCGATCCTGATGGT
CGGTTTGCAGGGCTCGGGCAAGACCACCACCACGGCGAAGCTGGCCAAGCGCCTCAAGGATCGCGAGAAGAAGCGGGTGC
TGATGGCGTCGCTGGACACCAACCGCCCGGCCGCCATGGAGCAGCTGGCGATCCTGGGCCAGCAGATCGGCGTCGATACC
CTGCCCATCGTGCCGGGCGAGAATGCGGTGCAGATTGCGAAACGCGCCAAGCAGCAGGCGACGCTGGGCGGCTATGACGT
CTATATGCTCGACACCGCCGGCCGGCTGCATATCGACGAAGTGCTGATGGACGAGGTGCAGGCGGTCCGCGACGTGGCCA
GCCCGCGCGAGACGCTGCTGGTCGTCGACGGGTTGACCGGCCAGGACGCGGTGAACGTCGCGGCCGAGTTCGACGGCAAG
GTGGGCATCTCGGGCGTGGTGCTGACCCGGATGGACGGCGACGGCCGCGGCGGTGCGGCGCTGTCGATGCGCGCCGTCAC
CGGCAAGCCGATCCGCTTCGTGGGCCTGGGCGAAAAGATGGATGCGCTGGAGGCCTTCGACGCGCAGCGCATCGCCGGCC
GCATCCTCGGCATGGGCGACATCGTGGCCCTGGTCGAGAAGGCGCAGGAGGTGCTGGAGGTCGAGCAGGCCGAGCGCATG
ATGAAGCGCTTCCAGAAGGGCATGTTCAACATGAACGACCTGCGGGGCCAGCTTGAGCAGATGCTCAAGATGGGCGGCAT
GCAGTCGATCATGGGCATGATGCCCGGCATGGGCAAGATGGCCAAGCAGGCCGAGGCCGCCGGCTTCGACGACAAGGCGA
TCAAGCGCCAGATCGCGCTGATCAACTCGATGACGAAAAAGGAACGCGCCAATCCCGACCTGCTGCAGGCTAGCCGCAAG
AAGCGCATCGCGGCCGGCGCCGGCATGGAAGTGTCCGAGCTGAACAAGCTTCTGAAGATGCAGAAGCAGATGGCCGACAC
GATGAAGAAGCTGGGCAAGATGGGCAAGGGCGGGCTGCTGAAGCAAGCCATGCGCGCCATGACCGGCAAGGGCGGCGGGC
TGCCCGACATGGGCAATGTCGATCCCGAAAAGATGGCCGAGGCGACCAAGATGCTGCAGGACCCCAAGGGGCTGGGTGGG
CAGTTGGGCGGCATGAACCTGCCCGGCGGGCTCTCGGGCCTGTTCGGAAAGAAGTGA

Upstream 100 bases:

>100_bases
GCCTTGCCGGGGATCGCCCCCCGTCAGCGCGTTGCGCCCACGGGGGCGTTACTGTTTATTCGCGCCCATCCGGGCAACGG
CAACCATTGGAGGGCCGCCG

Downstream 100 bases:

>100_bases
GCGCATGATCCGGCTTGCCGACACTCCGCTGATTGCGACCGAGCGTCTGGTCCTGCGCGCGCCGCAGGCCGGCGACTGGC
CGGCATGGCGCGATTTCGCG

Product: signal recognition particle protein

Products: NA

Alternate protein names: Fifty-four homolog [H]

Number of amino acids: Translated: 498; Mature: 498

Protein sequence:

>498_residues
MFENLSDRLGGVFDRLTKQGALSEDDVAAAMREVRVALLEADVSLPVARNFVKAVTQKATGAAVTKSITPGQQVVKIVHD
ELIKVLQGEGAPDALRIDNPPAPILMVGLQGSGKTTTTAKLAKRLKDREKKRVLMASLDTNRPAAMEQLAILGQQIGVDT
LPIVPGENAVQIAKRAKQQATLGGYDVYMLDTAGRLHIDEVLMDEVQAVRDVASPRETLLVVDGLTGQDAVNVAAEFDGK
VGISGVVLTRMDGDGRGGAALSMRAVTGKPIRFVGLGEKMDALEAFDAQRIAGRILGMGDIVALVEKAQEVLEVEQAERM
MKRFQKGMFNMNDLRGQLEQMLKMGGMQSIMGMMPGMGKMAKQAEAAGFDDKAIKRQIALINSMTKKERANPDLLQASRK
KRIAAGAGMEVSELNKLLKMQKQMADTMKKLGKMGKGGLLKQAMRAMTGKGGGLPDMGNVDPEKMAEATKMLQDPKGLGG
QLGGMNLPGGLSGLFGKK

Sequences:

>Translated_498_residues
MFENLSDRLGGVFDRLTKQGALSEDDVAAAMREVRVALLEADVSLPVARNFVKAVTQKATGAAVTKSITPGQQVVKIVHD
ELIKVLQGEGAPDALRIDNPPAPILMVGLQGSGKTTTTAKLAKRLKDREKKRVLMASLDTNRPAAMEQLAILGQQIGVDT
LPIVPGENAVQIAKRAKQQATLGGYDVYMLDTAGRLHIDEVLMDEVQAVRDVASPRETLLVVDGLTGQDAVNVAAEFDGK
VGISGVVLTRMDGDGRGGAALSMRAVTGKPIRFVGLGEKMDALEAFDAQRIAGRILGMGDIVALVEKAQEVLEVEQAERM
MKRFQKGMFNMNDLRGQLEQMLKMGGMQSIMGMMPGMGKMAKQAEAAGFDDKAIKRQIALINSMTKKERANPDLLQASRK
KRIAAGAGMEVSELNKLLKMQKQMADTMKKLGKMGKGGLLKQAMRAMTGKGGGLPDMGNVDPEKMAEATKMLQDPKGLGG
QLGGMNLPGGLSGLFGKK
>Mature_498_residues
MFENLSDRLGGVFDRLTKQGALSEDDVAAAMREVRVALLEADVSLPVARNFVKAVTQKATGAAVTKSITPGQQVVKIVHD
ELIKVLQGEGAPDALRIDNPPAPILMVGLQGSGKTTTTAKLAKRLKDREKKRVLMASLDTNRPAAMEQLAILGQQIGVDT
LPIVPGENAVQIAKRAKQQATLGGYDVYMLDTAGRLHIDEVLMDEVQAVRDVASPRETLLVVDGLTGQDAVNVAAEFDGK
VGISGVVLTRMDGDGRGGAALSMRAVTGKPIRFVGLGEKMDALEAFDAQRIAGRILGMGDIVALVEKAQEVLEVEQAERM
MKRFQKGMFNMNDLRGQLEQMLKMGGMQSIMGMMPGMGKMAKQAEAAGFDDKAIKRQIALINSMTKKERANPDLLQASRK
KRIAAGAGMEVSELNKLLKMQKQMADTMKKLGKMGKGGLLKQAMRAMTGKGGGLPDMGNVDPEKMAEATKMLQDPKGLGG
QLGGMNLPGGLSGLFGKK

Specific function: Necessary for efficient export of extracytoplasmic proteins. Binds to the signal sequence when it emerges from the ribosomes [H]

COG id: COG0541

COG function: function code U; Signal recognition particle GTPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding SRP family [H]

Homologues:

Organism=Homo sapiens, GI4507215, Length=492, Percent_Identity=28.8617886178862, Blast_Score=187, Evalue=2e-47,
Organism=Homo sapiens, GI226371618, Length=392, Percent_Identity=31.3775510204082, Blast_Score=172, Evalue=5e-43,
Organism=Homo sapiens, GI23308697, Length=321, Percent_Identity=28.3489096573209, Blast_Score=102, Evalue=1e-21,
Organism=Homo sapiens, GI295424842, Length=321, Percent_Identity=28.3489096573209, Blast_Score=101, Evalue=2e-21,
Organism=Homo sapiens, GI89061728, Length=161, Percent_Identity=32.2981366459627, Blast_Score=97, Evalue=3e-20,
Organism=Escherichia coli, GI1788963, Length=420, Percent_Identity=50.9523809523809, Blast_Score=418, Evalue=1e-118,
Organism=Escherichia coli, GI1789874, Length=261, Percent_Identity=33.3333333333333, Blast_Score=132, Evalue=6e-32,
Organism=Caenorhabditis elegans, GI17539958, Length=490, Percent_Identity=29.1836734693878, Blast_Score=196, Evalue=2e-50,
Organism=Caenorhabditis elegans, GI193206261, Length=322, Percent_Identity=29.1925465838509, Blast_Score=101, Evalue=8e-22,
Organism=Saccharomyces cerevisiae, GI6325345, Length=492, Percent_Identity=30.8943089430894, Blast_Score=195, Evalue=1e-50,
Organism=Saccharomyces cerevisiae, GI6320498, Length=311, Percent_Identity=27.9742765273312, Blast_Score=84, Evalue=5e-17,
Organism=Drosophila melanogaster, GI17647949, Length=509, Percent_Identity=29.2730844793713, Blast_Score=196, Evalue=4e-50,
Organism=Drosophila melanogaster, GI24641198, Length=301, Percent_Identity=27.2425249169435, Blast_Score=96, Evalue=5e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR000897
- InterPro:   IPR013822
- InterPro:   IPR004780
- InterPro:   IPR004125 [H]

Pfam domain/function: PF00448 SRP54; PF02881 SRP54_N; PF02978 SRP_SPB [H]

EC number: NA

Molecular weight: Translated: 53190; Mature: 53190

Theoretical pI: Translated: 10.26; Mature: 10.26

Prosite motif: PS00300 SRP54

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
7.0 %Met     (Translated Protein)
7.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
7.0 %Met     (Mature Protein)
7.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFENLSDRLGGVFDRLTKQGALSEDDVAAAMREVRVALLEADVSLPVARNFVKAVTQKAT
CCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHC
GAAVTKSITPGQQVVKIVHDELIKVLQGEGAPDALRIDNPPAPILMVGLQGSGKTTTTAK
CHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCEEEEEECCCCCCHHHHH
LAKRLKDREKKRVLMASLDTNRPAAMEQLAILGQQIGVDTLPIVPGENAVQIAKRAKQQA
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHH
TLGGYDVYMLDTAGRLHIDEVLMDEVQAVRDVASPRETLLVVDGLTGQDAVNVAAEFDGK
CCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHCCCC
VGISGVVLTRMDGDGRGGAALSMRAVTGKPIRFVGLGEKMDALEAFDAQRIAGRILGMGD
CCCCEEEEEEECCCCCCCCEEEEEECCCCCEEEEECCCHHHHHHHHHHHHHHHHHCCHHH
IVALVEKAQEVLEVEQAERMMKRFQKGMFNMNDLRGQLEQMLKMGGMQSIMGMMPGMGKM
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHCCCCHHH
AKQAEAAGFDDKAIKRQIALINSMTKKERANPDLLQASRKKRIAAGAGMEVSELNKLLKM
HHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
QKQMADTMKKLGKMGKGGLLKQAMRAMTGKGGGLPDMGNVDPEKMAEATKMLQDPKGLGG
HHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCC
QLGGMNLPGGLSGLFGKK
CCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MFENLSDRLGGVFDRLTKQGALSEDDVAAAMREVRVALLEADVSLPVARNFVKAVTQKAT
CCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHC
GAAVTKSITPGQQVVKIVHDELIKVLQGEGAPDALRIDNPPAPILMVGLQGSGKTTTTAK
CHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCEEEEEECCCCCCHHHHH
LAKRLKDREKKRVLMASLDTNRPAAMEQLAILGQQIGVDTLPIVPGENAVQIAKRAKQQA
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHH
TLGGYDVYMLDTAGRLHIDEVLMDEVQAVRDVASPRETLLVVDGLTGQDAVNVAAEFDGK
CCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHCCCC
VGISGVVLTRMDGDGRGGAALSMRAVTGKPIRFVGLGEKMDALEAFDAQRIAGRILGMGD
CCCCEEEEEEECCCCCCCCEEEEEECCCCCEEEEECCCHHHHHHHHHHHHHHHHHCCHHH
IVALVEKAQEVLEVEQAERMMKRFQKGMFNMNDLRGQLEQMLKMGGMQSIMGMMPGMGKM
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHCCCCHHH
AKQAEAAGFDDKAIKRQIALINSMTKKERANPDLLQASRKKRIAAGAGMEVSELNKLLKM
HHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
QKQMADTMKKLGKMGKGGLLKQAMRAMTGKGGGLPDMGNVDPEKMAEATKMLQDPKGLGG
HHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCC
QLGGMNLPGGLSGLFGKK
CCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11557893 [H]