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The map label for this gene is ptmB [H]

Identifier: 119386261

GI number: 119386261

Start: 698668

End: 699378

Strand: Direct

Name: ptmB [H]

Synonym: Pden_3550

Alternate gene names: 119386261

Gene position: 698668-699378 (Clockwise)

Preceding gene: 119386260

Following gene: 119386262

Centisome position: 40.38

GC content: 68.35

Gene sequence:

>711_bases
ATGAAGATCGCGATTATTCCCGCCCGTGGTGGCAGCAAGCGTATTCCCCGTAAGAACATCCGTCCCTTCGGCGGCCGCCC
GATGATCGCCTGGCCGATCGCCGCCGCGCGCGACAGCGGGCTTTTCGATCATGTCATCGTCTCGACCGACGATGCCGAGA
TCGCCGAAACCGCCCTGGCCCACGGCGCCGAGGTGCCCTTTCCGCGTCCGGTCGAACTGGCCGACGACTTCACCCCCACC
CGCGCGGTGATCAATCACGCGATCCGCGCCATGGAGGAGGCCCAGGGGCGCGAGGTCACGCTGGCCTGCTGCATTTACGC
CACCTCGGGCTTTCTCGATGCCTCGGATCTCGTCGGTGCGCATGGGTTGCTGGCGGCGGAGCCGGCTGCGGGCTTCGTCT
TCGCCGCGCTGCATTTTCCGCATCCGCCCCAGCGCGCGCTGTGCCGGGGGCCAGAGGGCGGCGTCGCGATGCTGCATCCC
GAACATGCCGGAACCCGCAGCCAGGACCTCTGTGAGACCTTCCACGACGCCGCGCAGTTCTACTGGGGTCGCCGCGACGC
CTTTCTCAGCGGGGCGCCGATGTTCTCGACACTCGCCCGGCCCTGGATCCTGCCGCGCGACCGTGCGCTCGATATCGATA
CGCCCGAGGACTGGGATTGGGCCGAGCGGTTGCTGGCCTTGCGCCAAGCCGCCGGGGAAATCCCGGCATGA

Upstream 100 bases:

>100_bases
ATCCCCGCCGGGCAGGACGGTTGCCCCTTTACTTGGCCGATCCCCGGCGCATAGGTAACGGGGAGCATATCCCTTTTCAG
GCAACATCCTTTCTCCGGAC

Downstream 100 bases:

>100_bases
GCCTGCCTCCGGTCGTTTTTCGTTGCACCGCCAACGCGCGGATCGGCATGGGCCATCTGGCGCGCTGCCGCGAGATGGCG
CGGGAACTGGGCGCGCGGGG

Product: acylneuraminate cytidylyltransferase

Products: diphosphate; CMP-N-acylneuraminate

Alternate protein names: NA

Number of amino acids: Translated: 236; Mature: 236

Protein sequence:

>236_residues
MKIAIIPARGGSKRIPRKNIRPFGGRPMIAWPIAAARDSGLFDHVIVSTDDAEIAETALAHGAEVPFPRPVELADDFTPT
RAVINHAIRAMEEAQGREVTLACCIYATSGFLDASDLVGAHGLLAAEPAAGFVFAALHFPHPPQRALCRGPEGGVAMLHP
EHAGTRSQDLCETFHDAAQFYWGRRDAFLSGAPMFSTLARPWILPRDRALDIDTPEDWDWAERLLALRQAAGEIPA

Sequences:

>Translated_236_residues
MKIAIIPARGGSKRIPRKNIRPFGGRPMIAWPIAAARDSGLFDHVIVSTDDAEIAETALAHGAEVPFPRPVELADDFTPT
RAVINHAIRAMEEAQGREVTLACCIYATSGFLDASDLVGAHGLLAAEPAAGFVFAALHFPHPPQRALCRGPEGGVAMLHP
EHAGTRSQDLCETFHDAAQFYWGRRDAFLSGAPMFSTLARPWILPRDRALDIDTPEDWDWAERLLALRQAAGEIPA
>Mature_236_residues
MKIAIIPARGGSKRIPRKNIRPFGGRPMIAWPIAAARDSGLFDHVIVSTDDAEIAETALAHGAEVPFPRPVELADDFTPT
RAVINHAIRAMEEAQGREVTLACCIYATSGFLDASDLVGAHGLLAAEPAAGFVFAALHFPHPPQRALCRGPEGGVAMLHP
EHAGTRSQDLCETFHDAAQFYWGRRDAFLSGAPMFSTLARPWILPRDRALDIDTPEDWDWAERLLALRQAAGEIPA

Specific function: Required for biosynthesis of LAH modification in the post-translational modification of Campylobacter coli flagellin [H]

COG id: COG1083

COG function: function code M; CMP-N-acetylneuraminic acid synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CMP-NeuNAc synthase family [H]

Homologues:

Organism=Homo sapiens, GI8923900, Length=225, Percent_Identity=31.1111111111111, Blast_Score=74, Evalue=8e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003329 [H]

Pfam domain/function: PF02348 CTP_transf_3 [H]

EC number: 2.7.7.43

Molecular weight: Translated: 25630; Mature: 25630

Theoretical pI: Translated: 6.03; Mature: 6.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIAIIPARGGSKRIPRKNIRPFGGRPMIAWPIAAARDSGLFDHVIVSTDDAEIAETALA
CEEEEEECCCCCCCCCCCCCCCCCCCCEEEECCHHHCCCCCEEEEEEECCCHHHHHHHHH
HGAEVPFPRPVELADDFTPTRAVINHAIRAMEEAQGREVTLACCIYATSGFLDASDLVGA
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEEEEEHHCCCCCHHHHHCC
HGLLAAEPAAGFVFAALHFPHPPQRALCRGPEGGVAMLHPEHAGTRSQDLCETFHDAAQF
CCCEECCCCCCEEEEEEECCCCCHHHHHCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHH
YWGRRDAFLSGAPMFSTLARPWILPRDRALDIDTPEDWDWAERLLALRQAAGEIPA
HCCCCHHHCCCCCHHHHHHCCCCCCCCCEECCCCCCCCCHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKIAIIPARGGSKRIPRKNIRPFGGRPMIAWPIAAARDSGLFDHVIVSTDDAEIAETALA
CEEEEEECCCCCCCCCCCCCCCCCCCCEEEECCHHHCCCCCEEEEEEECCCHHHHHHHHH
HGAEVPFPRPVELADDFTPTRAVINHAIRAMEEAQGREVTLACCIYATSGFLDASDLVGA
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEEEEEHHCCCCCHHHHHCC
HGLLAAEPAAGFVFAALHFPHPPQRALCRGPEGGVAMLHPEHAGTRSQDLCETFHDAAQF
CCCEECCCCCCEEEEEEECCCCCHHHHHCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHH
YWGRRDAFLSGAPMFSTLARPWILPRDRALDIDTPEDWDWAERLLALRQAAGEIPA
HCCCCHHHCCCCCHHHHHHCCCCCCCCCEECCCCCCCCCHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: CTP; N-acylneuraminate

Specific reaction: CTP + N-acylneuraminate = diphosphate + CMP-N-acylneuraminate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8825781 [H]