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The map label for this gene is yccK [H]

Identifier: 119385964

GI number: 119385964

Start: 407264

End: 408247

Strand: Direct

Name: yccK [H]

Synonym: Pden_3242

Alternate gene names: 119385964

Gene position: 407264-408247 (Clockwise)

Preceding gene: 119385963

Following gene: 119385965

Centisome position: 23.54

GC content: 61.08

Gene sequence:

>984_bases
ATGAAAACAAGGAGGCTTGGAAGCAGCGGGCTGGAAGTCTCGGCGCTCGGTCTCGGCTGCATGGGCCTGAGCTATGGATA
TGGACAGGCCACCGGGCACGGTGATGCAATTCGTCTCATTCGCACCGCCCATGCCCGTGGTGTCACCTTTTTCGACACCG
CCGAGGCTTATGGGCCTGGTCTCAATGAGGAGATTATAGGAGAGGCGCTGCAACCCGTTCGCGAGCATGTGGTGATCGCC
ACGAAGTTCGGCTTCAGGGACGGTGTGCCAGCGAACGGTCTCGACAGCCGCCCCGAGCGCATCCGCCACGTCGCAGATGC
GGCTTTGAAACGCCTCCGGACCGATCATATCGACATCTTCTACCAGCATCGCGTCGACCCGAACGTGCCCATCGAAGATG
TGGCAGGCACGGTCAGGGACCTCATCCATGAAGGCAAGGTGCGTCACTTCGGATTGTGTGAGGCTGGCGCCGACACGATC
CGCCGTGCGCAGGCGGTGCAGCCTCTGGCAGCCTTGCAAAGCGAATATTCCATGTGGTGGCGGGAACCGGAGACCGAAAT
CCTTCCGCTTCTCGATGAGCTTGGTATCGGCTTTGTGCCGTTCGCACCGCTCGGCAAAGGATTTCTGACAGGCAAGATCG
ACCAGAACGCCACCTTTGCGAAAGACGACTTTCGGGCATCCGTGCCGCGTTTCTCGCCCGAGGCGCTCAAGGCAAATCAG
GCGCTCGTCGACGTCATCGCGTCAATCGCTTCGGACAAGAACGTGACGCCCGCGCAGATCGCGCTGGCATGGTTGCTTGG
CCAGCGACCCTATATCGTCCCGATTCCCGGCACCACCAAGCTGAATCGGCTGGACGAGAACATTGGAGCGGCAACTGTCG
CGCTGTCTTCTGACGAGATGGCGCTGATCGGCCAGTCGCTCGACGCCATCGCCGTGCGGGGCGACCGCTATCCGGCATCC
CACCAGCAATTCGTCAACCGCTGA

Upstream 100 bases:

>100_bases
CGATCAGGAACGGCGCACGCTGGAGCGGGTGACGGACTGGCTTGGGCAACGATGAGAAATCGCGCCGCAGGTCTCTGCGG
TGCAATGATGGAGAAAGACG

Downstream 100 bases:

>100_bases
GGGCGCGCCGTTCAGACGCGACCTCTCCCGAACACAAGGACAACAGACATGACAAACGAACAGAAACTGAAGATCGGGCG
GCGGGGTTTCCTGGGTGCGG

Product: aldo/keto reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 327; Mature: 327

Protein sequence:

>327_residues
MKTRRLGSSGLEVSALGLGCMGLSYGYGQATGHGDAIRLIRTAHARGVTFFDTAEAYGPGLNEEIIGEALQPVREHVVIA
TKFGFRDGVPANGLDSRPERIRHVADAALKRLRTDHIDIFYQHRVDPNVPIEDVAGTVRDLIHEGKVRHFGLCEAGADTI
RRAQAVQPLAALQSEYSMWWREPETEILPLLDELGIGFVPFAPLGKGFLTGKIDQNATFAKDDFRASVPRFSPEALKANQ
ALVDVIASIASDKNVTPAQIALAWLLGQRPYIVPIPGTTKLNRLDENIGAATVALSSDEMALIGQSLDAIAVRGDRYPAS
HQQFVNR

Sequences:

>Translated_327_residues
MKTRRLGSSGLEVSALGLGCMGLSYGYGQATGHGDAIRLIRTAHARGVTFFDTAEAYGPGLNEEIIGEALQPVREHVVIA
TKFGFRDGVPANGLDSRPERIRHVADAALKRLRTDHIDIFYQHRVDPNVPIEDVAGTVRDLIHEGKVRHFGLCEAGADTI
RRAQAVQPLAALQSEYSMWWREPETEILPLLDELGIGFVPFAPLGKGFLTGKIDQNATFAKDDFRASVPRFSPEALKANQ
ALVDVIASIASDKNVTPAQIALAWLLGQRPYIVPIPGTTKLNRLDENIGAATVALSSDEMALIGQSLDAIAVRGDRYPAS
HQQFVNR
>Mature_327_residues
MKTRRLGSSGLEVSALGLGCMGLSYGYGQATGHGDAIRLIRTAHARGVTFFDTAEAYGPGLNEEIIGEALQPVREHVVIA
TKFGFRDGVPANGLDSRPERIRHVADAALKRLRTDHIDIFYQHRVDPNVPIEDVAGTVRDLIHEGKVRHFGLCEAGADTI
RRAQAVQPLAALQSEYSMWWREPETEILPLLDELGIGFVPFAPLGKGFLTGKIDQNATFAKDDFRASVPRFSPEALKANQ
ALVDVIASIASDKNVTPAQIALAWLLGQRPYIVPIPGTTKLNRLDENIGAATVALSSDEMALIGQSLDAIAVRGDRYPAS
HQQFVNR

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436969, Length=318, Percent_Identity=30.5031446540881, Blast_Score=120, Evalue=1e-27,
Organism=Homo sapiens, GI4504825, Length=315, Percent_Identity=30.4761904761905, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI27436971, Length=310, Percent_Identity=30.3225806451613, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI27436964, Length=307, Percent_Identity=29.3159609120521, Blast_Score=116, Evalue=3e-26,
Organism=Homo sapiens, GI27436962, Length=307, Percent_Identity=28.9902280130293, Blast_Score=113, Evalue=2e-25,
Organism=Homo sapiens, GI27436966, Length=307, Percent_Identity=28.9902280130293, Blast_Score=113, Evalue=2e-25,
Organism=Homo sapiens, GI223718702, Length=195, Percent_Identity=31.2820512820513, Blast_Score=79, Evalue=6e-15,
Organism=Homo sapiens, GI41327764, Length=195, Percent_Identity=30.7692307692308, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI41152114, Length=176, Percent_Identity=31.8181818181818, Blast_Score=76, Evalue=4e-14,
Organism=Escherichia coli, GI87081735, Length=316, Percent_Identity=32.9113924050633, Blast_Score=153, Evalue=1e-38,
Organism=Escherichia coli, GI1788070, Length=329, Percent_Identity=31.6109422492401, Blast_Score=131, Evalue=5e-32,
Organism=Escherichia coli, GI1789375, Length=325, Percent_Identity=28.9230769230769, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1787674, Length=308, Percent_Identity=30.1948051948052, Blast_Score=107, Evalue=7e-25,
Organism=Escherichia coli, GI1789199, Length=348, Percent_Identity=28.448275862069, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI1788081, Length=274, Percent_Identity=24.8175182481752, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI48994888, Length=270, Percent_Identity=28.5185185185185, Blast_Score=67, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6325169, Length=340, Percent_Identity=28.2352941176471, Blast_Score=127, Evalue=3e-30,
Organism=Saccharomyces cerevisiae, GI6325384, Length=333, Percent_Identity=27.027027027027, Blast_Score=100, Evalue=5e-22,
Organism=Saccharomyces cerevisiae, GI6323998, Length=317, Percent_Identity=25.8675078864353, Blast_Score=91, Evalue=3e-19,
Organism=Saccharomyces cerevisiae, GI6319958, Length=286, Percent_Identity=24.8251748251748, Blast_Score=87, Evalue=5e-18,
Organism=Saccharomyces cerevisiae, GI6319951, Length=316, Percent_Identity=25.6329113924051, Blast_Score=86, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6322615, Length=251, Percent_Identity=24.7011952191235, Blast_Score=77, Evalue=5e-15,
Organism=Drosophila melanogaster, GI24640980, Length=347, Percent_Identity=25.0720461095101, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI45549126, Length=347, Percent_Identity=25.0720461095101, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24646159, Length=314, Percent_Identity=26.1146496815287, Blast_Score=82, Evalue=7e-16,
Organism=Drosophila melanogaster, GI24646155, Length=157, Percent_Identity=32.484076433121, Blast_Score=78, Evalue=9e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 35552; Mature: 35552

Theoretical pI: Translated: 6.61; Mature: 6.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTRRLGSSGLEVSALGLGCMGLSYGYGQATGHGDAIRLIRTAHARGVTFFDTAEAYGPG
CCCCCCCCCCCEEEEHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCEEEECHHHHCCC
LNEEIIGEALQPVREHVVIATKFGFRDGVPANGLDSRPERIRHVADAALKRLRTDHIDIF
CCHHHHHHHHHHHHHHEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHEEEE
YQHRVDPNVPIEDVAGTVRDLIHEGKVRHFGLCEAGADTIRRAQAVQPLAALQSEYSMWW
EEECCCCCCCHHHHHHHHHHHHHCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHH
REPETEILPLLDELGIGFVPFAPLGKGFLTGKIDQNATFAKDDFRASVPRFSPEALKANQ
CCCCHHHHHHHHHCCCCCCCCCCCCCCCEEECCCCCCCCCCHHHHHCCCCCCHHHHHHHH
ALVDVIASIASDKNVTPAQIALAWLLGQRPYIVPIPGTTKLNRLDENIGAATVALSSDEM
HHHHHHHHHHCCCCCCHHHHHHHHHHCCCCEEEECCCCCHHHHHHHCCCEEEEEECCCCH
ALIGQSLDAIAVRGDRYPASHQQFVNR
HHHHCCCCEEEEECCCCCCHHHHHHCC
>Mature Secondary Structure
MKTRRLGSSGLEVSALGLGCMGLSYGYGQATGHGDAIRLIRTAHARGVTFFDTAEAYGPG
CCCCCCCCCCCEEEEHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCEEEECHHHHCCC
LNEEIIGEALQPVREHVVIATKFGFRDGVPANGLDSRPERIRHVADAALKRLRTDHIDIF
CCHHHHHHHHHHHHHHEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHEEEE
YQHRVDPNVPIEDVAGTVRDLIHEGKVRHFGLCEAGADTIRRAQAVQPLAALQSEYSMWW
EEECCCCCCCHHHHHHHHHHHHHCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHH
REPETEILPLLDELGIGFVPFAPLGKGFLTGKIDQNATFAKDDFRASVPRFSPEALKANQ
CCCCHHHHHHHHHCCCCCCCCCCCCCCCEEECCCCCCCCCCHHHHHCCCCCCHHHHHHHH
ALVDVIASIASDKNVTPAQIALAWLLGQRPYIVPIPGTTKLNRLDENIGAATVALSSDEM
HHHHHHHHHHCCCCCCHHHHHHHHHHCCCCEEEECCCCCHHHHHHHCCCEEEEEECCCCH
ALIGQSLDAIAVRGDRYPASHQQFVNR
HHHHCCCCEEEEECCCCCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9274031; 9384377; 9106203 [H]