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The map label for this gene is hypE [H]

Identifier: 119385834

GI number: 119385834

Start: 295803

End: 296858

Strand: Direct

Name: hypE [H]

Synonym: Pden_3112

Alternate gene names: 119385834

Gene position: 295803-296858 (Clockwise)

Preceding gene: 119385833

Following gene: 119385835

Centisome position: 17.1

GC content: 69.13

Gene sequence:

>1056_bases
ATGAACGCAATGGCTTTTGGAACCCTGCGCGACAGCCATGTGACCCTGTCGCATGGCGGTGGCGGCAAGGCGATGGCCGA
TCTGATCGAGACCGTCTTTTTTCCCGCCTTCGGCCCCGGATCGGGCGAGGATCAGGCGCGGCTGACGGCGGATGCGCTGT
GTGAACCCGGCGCGCGGCTGGCCTTGACCACCGACAGTTTCGTGGTCACGCCGCTGGAATTTCCCGGCGGCGATATCGGC
AAGCTGGCGGTCTGCGGCACGGTGAACGATCTGGCCGTCGGCGGGGCACGACCGCTGTGGCTGTCGGCGGCGTTCATTAT
CGAGGAAGGCTGCGAGATTGCGCTGTTGCAGCGCGTGGTCGCCTCGATGGCGCGTGAGGCGGCGCTGGCCGGGGTGCGGA
TCGTGACCGGCGACACCAAGGTCGTCGGGCGCGGATCGGCGGACGGGGTGTTCGTCACCACCTCGGGCGTCGGCGTGATC
CCGGCGGGGCGCGATCTGGTTGCGGCGCGGATCAGGCCGGGCGATGTCGTGCTGGTCAATGGCGTGCTGGGCGATCATGG
CGCGGCCATTCTGGCGGCGCGCGGCGATCTGGCGCTGTCGACGGATCTGGTCTCGGACTGTCAGGGGCTTGGGCATCTGA
TGGAGGCGGTGCTGGCCGCCGCCCCCGGCACCCGAGCCGCCCGCGATGCGACCCGCGGAGGGCTTGCCGCGGCGCTGAAT
GAAATGGCGCTGGCGGCAGGATGCGGCATCGAAATCAGGGAAGATGCGCTGCCCCTGCGCCCCGAGGTGCGCGGGGTCTG
CGAAATTCTTGGCCTTGATCCGCTCTATCTTGCCAATGAGGGAACCTTGGTCCTGTTCGTGCCCGAGGCCGAGGCTGAGG
CTGCGCTGTGCGCGATGCGTTCCCGCCCCGAAGGGCAGGGCGCCGCAATCATCGGCCGCGCCGTCGCCGCATCCGAGGGG
GGCGCCCATACGGCCCGTGTGCAGATGGTGACCTCCTTTGGCGGGCGCCGCATCGTCGACCGCCTCGTGGGCGAACAACT
GCCGCGGATCTGCTGA

Upstream 100 bases:

>100_bases
GATGCCGCTGGGGGCGCTGATGGTCAGTTCGGAAGGGGCCTGTGCGGCCTATTGGCAATATGGCGGTGCGCGGGTTGCAG
CGGAATAGGGCGGGCAGAAC

Downstream 100 bases:

>100_bases
AACGGACCCTTGCCGGCTTTGCGCGACCTCGGCAGCCCGGACGGGGTGCAGCGAGCCTGTTTCGTCATATTTGGCCGCTT
TTGCACCGAGGAGAAAACCC

Product: hydrogenase expression/formation protein HypE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 351; Mature: 351

Protein sequence:

>351_residues
MNAMAFGTLRDSHVTLSHGGGGKAMADLIETVFFPAFGPGSGEDQARLTADALCEPGARLALTTDSFVVTPLEFPGGDIG
KLAVCGTVNDLAVGGARPLWLSAAFIIEEGCEIALLQRVVASMAREAALAGVRIVTGDTKVVGRGSADGVFVTTSGVGVI
PAGRDLVAARIRPGDVVLVNGVLGDHGAAILAARGDLALSTDLVSDCQGLGHLMEAVLAAAPGTRAARDATRGGLAAALN
EMALAAGCGIEIREDALPLRPEVRGVCEILGLDPLYLANEGTLVLFVPEAEAEAALCAMRSRPEGQGAAIIGRAVAASEG
GAHTARVQMVTSFGGRRIVDRLVGEQLPRIC

Sequences:

>Translated_351_residues
MNAMAFGTLRDSHVTLSHGGGGKAMADLIETVFFPAFGPGSGEDQARLTADALCEPGARLALTTDSFVVTPLEFPGGDIG
KLAVCGTVNDLAVGGARPLWLSAAFIIEEGCEIALLQRVVASMAREAALAGVRIVTGDTKVVGRGSADGVFVTTSGVGVI
PAGRDLVAARIRPGDVVLVNGVLGDHGAAILAARGDLALSTDLVSDCQGLGHLMEAVLAAAPGTRAARDATRGGLAAALN
EMALAAGCGIEIREDALPLRPEVRGVCEILGLDPLYLANEGTLVLFVPEAEAEAALCAMRSRPEGQGAAIIGRAVAASEG
GAHTARVQMVTSFGGRRIVDRLVGEQLPRIC
>Mature_351_residues
MNAMAFGTLRDSHVTLSHGGGGKAMADLIETVFFPAFGPGSGEDQARLTADALCEPGARLALTTDSFVVTPLEFPGGDIG
KLAVCGTVNDLAVGGARPLWLSAAFIIEEGCEIALLQRVVASMAREAALAGVRIVTGDTKVVGRGSADGVFVTTSGVGVI
PAGRDLVAARIRPGDVVLVNGVLGDHGAAILAARGDLALSTDLVSDCQGLGHLMEAVLAAAPGTRAARDATRGGLAAALN
EMALAAGCGIEIREDALPLRPEVRGVCEILGLDPLYLANEGTLVLFVPEAEAEAALCAMRSRPEGQGAAIIGRAVAASEG
GAHTARVQMVTSFGGRRIVDRLVGEQLPRIC

Specific function: Unknown

COG id: COG0309

COG function: function code O; Hydrogenase maturation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypE family [H]

Homologues:

Organism=Escherichia coli, GI226510967, Length=343, Percent_Identity=50.4373177842566, Blast_Score=305, Evalue=2e-84,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR011854
- InterPro:   IPR016188 [H]

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C [H]

EC number: NA

Molecular weight: Translated: 35720; Mature: 35720

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAMAFGTLRDSHVTLSHGGGGKAMADLIETVFFPAFGPGSGEDQARLTADALCEPGARL
CCCEEEECCCCCEEEEEECCCCHHHHHHHHHHHCCCCCCCCCCCCHHEEHHHHCCCCCEE
ALTTDSFVVTPLEFPGGDIGKLAVCGTVNDLAVGGARPLWLSAAFIIEEGCEIALLQRVV
EEEECCEEEEEECCCCCCCCCEEEECCCHHHHCCCCCHHHHHHHHHHHCCCHHHHHHHHH
ASMAREAALAGVRIVTGDTKVVGRGSADGVFVTTSGVGVIPAGRDLVAARIRPGDVVLVN
HHHHHHHHHCCEEEEECCEEEEECCCCCCEEEEECCCEEECCCCCEEEEEECCCCEEEEE
GVLGDHGAAILAARGDLALSTDLVSDCQGLGHLMEAVLAAAPGTRAARDATRGGLAAALN
CEECCCCCEEEEECCCCEEHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCHHHHHHH
EMALAAGCGIEIREDALPLRPEVRGVCEILGLDPLYLANEGTLVLFVPEAEAEAALCAMR
HHHHHHCCCCEEECCCCCCCHHHHHHHHHHCCCCEEEECCCEEEEEECCCCHHHHHHHHH
SRPEGQGAAIIGRAVAASEGGAHTARVQMVTSFGGRRIVDRLVGEQLPRIC
CCCCCCCCEEEEEEHCCCCCCCCEEEEEEEECCCCHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MNAMAFGTLRDSHVTLSHGGGGKAMADLIETVFFPAFGPGSGEDQARLTADALCEPGARL
CCCEEEECCCCCEEEEEECCCCHHHHHHHHHHHCCCCCCCCCCCCHHEEHHHHCCCCCEE
ALTTDSFVVTPLEFPGGDIGKLAVCGTVNDLAVGGARPLWLSAAFIIEEGCEIALLQRVV
EEEECCEEEEEECCCCCCCCCEEEECCCHHHHCCCCCHHHHHHHHHHHCCCHHHHHHHHH
ASMAREAALAGVRIVTGDTKVVGRGSADGVFVTTSGVGVIPAGRDLVAARIRPGDVVLVN
HHHHHHHHHCCEEEEECCEEEEECCCCCCEEEEECCCEEECCCCCEEEEEECCCCEEEEE
GVLGDHGAAILAARGDLALSTDLVSDCQGLGHLMEAVLAAAPGTRAARDATRGGLAAALN
CEECCCCCEEEEECCCCEEHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCHHHHHHH
EMALAAGCGIEIREDALPLRPEVRGVCEILGLDPLYLANEGTLVLFVPEAEAEAALCAMR
HHHHHHCCCCEEECCCCCCCHHHHHHHHHHCCCCEEEECCCEEEEEECCCCHHHHHHHHH
SRPEGQGAAIIGRAVAASEGGAHTARVQMVTSFGGRRIVDRLVGEQLPRIC
CCCCCCCCEEEEEEHCCCCCCCCEEEEEEEECCCCHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8497190 [H]