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The map label for this gene is ccdA [H]

Identifier: 119385691

GI number: 119385691

Start: 138190

End: 138933

Strand: Direct

Name: ccdA [H]

Synonym: Pden_2966

Alternate gene names: 119385691

Gene position: 138190-138933 (Clockwise)

Preceding gene: 119385690

Following gene: 119385693

Centisome position: 7.99

GC content: 68.41

Gene sequence:

>744_bases
ATGTTGGGAATCGAGCTTGCAGATGCCGCCTTCCTGCCCGCCGCGACGGTCGCGCTGCTGGCCGGGATCCTGTCCTTTCT
GTCGCCCTGCGTGCTGCCGATCGTGCCGCCCTATCTGGCCTACATGACCGGGGTCGGGGTCGGCGGGCTGAAATCGGGCG
AGCGCAGCGCCGTGGTTCCGGCGCTGTTCTTCGTCATGGGCCTGTCCACGGTGTTTCTGCTGATGGGCATGGCGGCCTCG
GCCTTCGGGCGGATGTTCCTGCAATGGCAGGACCTGCTGGCGCGCGGCGCGGGCGTGGTGGTGATCCTGCTGGGCCTGCA
TTTCCTGCATATCATCCGCATCCCCTTTCTGGATGCCGAGGCGCGCATCGACGCGCAGGAGCGGGGCGGCAGCGCGCTGG
GGGCCTATGCCCTGGGCCTGGCCTTCGCCTTTGGCTGGACGCCCTGCATCGGGCCGCAGCTCGGCATGATCCTGTCCCTG
GCCGCGACCGGCGGGGCGATGGGCAAGGGCACGGCGCTGCTGGCGGTCTATGCGCTGGGGCTGGGCATCCCCTTCCTGCT
GTCGGCCATCTTCATCAACCGCGCCATCGGCCTGATGAACCGCATCAAGCCGCATCTGAAGCTGATCGAGCGCGTCATGG
GCGGCCTGCTGGTCGTGGTCGGCGCGGCGCTGCTGACCGGAGCGTTTCCGGCCTTCGCCTATTGGCTGCTGGAGACCTTT
CCCTGGCTGGCCGCGCTGGGTTAA

Upstream 100 bases:

>100_bases
CGCGGCTGGTGGTCCCTGGGCTGATCTGTCGCAGCCTTCCACGAAAGAGTGACGGGCGCGGGGCTTTCCCGCGCCCTTTC
CTTGCGCCAAGGTGCCCGAC

Downstream 100 bases:

>100_bases
TCCCAGTTCGGCGGACGCTTTTCCAGGAATGCCTGGATGCCCTCGGCCGTGTCGGGCAGCAGCAGGTTCTCGCAGATCAC
CGCGCCCGCCGTCGCATAGG

Product: cytochrome c biogenesis protein, transmembrane region

Products: DsbDoxidized; DsbGreduced [C]

Alternate protein names: NA

Number of amino acids: Translated: 247; Mature: 247

Protein sequence:

>247_residues
MLGIELADAAFLPAATVALLAGILSFLSPCVLPIVPPYLAYMTGVGVGGLKSGERSAVVPALFFVMGLSTVFLLMGMAAS
AFGRMFLQWQDLLARGAGVVVILLGLHFLHIIRIPFLDAEARIDAQERGGSALGAYALGLAFAFGWTPCIGPQLGMILSL
AATGGAMGKGTALLAVYALGLGIPFLLSAIFINRAIGLMNRIKPHLKLIERVMGGLLVVVGAALLTGAFPAFAYWLLETF
PWLAALG

Sequences:

>Translated_247_residues
MLGIELADAAFLPAATVALLAGILSFLSPCVLPIVPPYLAYMTGVGVGGLKSGERSAVVPALFFVMGLSTVFLLMGMAAS
AFGRMFLQWQDLLARGAGVVVILLGLHFLHIIRIPFLDAEARIDAQERGGSALGAYALGLAFAFGWTPCIGPQLGMILSL
AATGGAMGKGTALLAVYALGLGIPFLLSAIFINRAIGLMNRIKPHLKLIERVMGGLLVVVGAALLTGAFPAFAYWLLETF
PWLAALG
>Mature_247_residues
MLGIELADAAFLPAATVALLAGILSFLSPCVLPIVPPYLAYMTGVGVGGLKSGERSAVVPALFFVMGLSTVFLLMGMAAS
AFGRMFLQWQDLLARGAGVVVILLGLHFLHIIRIPFLDAEARIDAQERGGSALGAYALGLAFAFGWTPCIGPQLGMILSL
AATGGAMGKGTALLAVYALGLGIPFLLSAIFINRAIGLMNRIKPHLKLIERVMGGLLVVVGAALLTGAFPAFAYWLLETF
PWLAALG

Specific function: Required for cytochrome c synthesis and stage V of sporulation. Might transfer reducing equivalents across the cytoplasmic membrane, promoting efficient disulfide bond isomerization of proteins localized on the outer surface of the membrane or in the spor

COG id: COG0785

COG function: function code O; Cytochrome c biogenesis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DsbD family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003834 [H]

Pfam domain/function: PF02683 DsbD [H]

EC number: 1.8.1.8 [C]

Molecular weight: Translated: 25727; Mature: 25727

Theoretical pI: Translated: 9.15; Mature: 9.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHCC
>Mature Secondary Structure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HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DsbGoxidized; DsbDreduced/thiol:disulfide reductase [C]

Specific reaction: DsbDreduced/thiol:disulfide reductase + DsbCoxidized = DsbDoxidized + DsbCreduced DsbGoxidized + DsbDreduced/thiol:disulfide reductase = DsbGreduced + DsbDoxidized [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]